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IL163611A0 - Preparation of n-methyl-3-hydrocy-3-(2-thienyl) propylamine via novel thiophene derivatives containing carbamete groups as - Google Patents

Preparation of n-methyl-3-hydrocy-3-(2-thienyl) propylamine via novel thiophene derivatives containing carbamete groups as

Info

Publication number
IL163611A0
IL163611A0 IL16361103A IL16361103A IL163611A0 IL 163611 A0 IL163611 A0 IL 163611A0 IL 16361103 A IL16361103 A IL 16361103A IL 16361103 A IL16361103 A IL 16361103A IL 163611 A0 IL163611 A0 IL 163611A0
Authority
IL
Israel
Prior art keywords
carbamete
hydrocy
thienyl
methyl
groups
Prior art date
Application number
IL16361103A
Other languages
English (en)
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of IL163611A0 publication Critical patent/IL163611A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL16361103A 2002-02-22 2003-01-30 Preparation of n-methyl-3-hydrocy-3-(2-thienyl) propylamine via novel thiophene derivatives containing carbamete groups as IL163611A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10207586A DE10207586A1 (de) 2002-02-22 2002-02-22 Herstellung von N-Methyl-3-hydroxy-3-(2-thienyl)propanamin über neue carbamatgruppenhaltige Thiophenderivate als Zwischenprodukte
PCT/EP2003/000910 WO2003070720A1 (en) 2002-02-22 2003-01-30 Preparation of n-methyl-3-hydroxy- 3-(2-thienyl)propylamine via novel thiophene derivatives containing carbamate groups as intermediates

Publications (1)

Publication Number Publication Date
IL163611A0 true IL163611A0 (en) 2005-12-18

Family

ID=27740334

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16361103A IL163611A0 (en) 2002-02-22 2003-01-30 Preparation of n-methyl-3-hydrocy-3-(2-thienyl) propylamine via novel thiophene derivatives containing carbamete groups as

Country Status (11)

Country Link
US (1) US20050171360A1 (xx)
EP (1) EP1476439A1 (xx)
JP (1) JP2005519077A (xx)
KR (1) KR20040096593A (xx)
AU (1) AU2003206800A1 (xx)
CA (1) CA2477082A1 (xx)
DE (1) DE10207586A1 (xx)
HR (1) HRP20040744A2 (xx)
IL (1) IL163611A0 (xx)
PL (1) PL370432A1 (xx)
WO (1) WO2003070720A1 (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060167278A1 (en) * 2002-05-20 2006-07-27 Mitsubishi Rayon Co. Ltd. Propanolamine derivatives, process for preparation of 3-n-methylamino-1-(2-thienyl)-1-propanols and process for preparation of propanolamine derivatives
EP1566383A1 (en) * 2004-02-19 2005-08-24 Lonza AG Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols
SI1720852T1 (sl) * 2004-02-19 2012-11-30 Lonza Ag Postopek za pripravo enantiomerno čistih substituiranih aminoalkoholov
CZ297560B6 (cs) * 2004-10-26 2007-02-07 Zentiva, A. S. Zpusob výroby hydrochloridu (S)-N-methyl-3-(1-naftyloxy)-3-(2-thienyl)propylaminu (duloxetinu)
EP1874754A1 (en) * 2005-03-14 2008-01-09 Teva Pharmaceutical Industries Ltd Pure duloxetine hydrochloride
JPWO2006104249A1 (ja) * 2005-03-29 2008-09-11 日本ゼオン株式会社 １−（２−チエニル）−３−アルキルアミノプロピルアルコールの製造方法
MY148074A (en) 2005-05-10 2013-02-28 Novartis Ag Pharmaceutical compositions comprising imatinib and a release retardant
EP1838692A2 (en) 2005-09-22 2007-10-03 Teva Pharmaceutical Industries Ltd Dnt-maleate and methods of preparation thereof
US20070281989A1 (en) * 2006-05-31 2007-12-06 Santiago Ini Process for preparing duloxetine and intermediates thereof
EP1899317A2 (en) * 2006-04-17 2008-03-19 Teva Pharmaceutical Industries Ltd Enantiomers of n,n-dimethyl-3-(2-thienyl)-3-hydroxypropanamine borane as intermediates in the synthesis of duloxetine
WO2008004191A2 (en) 2006-07-03 2008-01-10 Ranbaxy Laboratories Limited Process for the preparation of enantiomerically pure salts of n-methyl-3- ( 1-naphthaleneoxy) -3- (2-thienyl) propanamine
CN101657438A (zh) * 2006-12-22 2010-02-24 斯索恩有限公司 制备度洛西汀和相关化合物的方法
US8148549B2 (en) * 2009-03-12 2012-04-03 Sci Pharmtech, Inc. Preparation of (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl) propylamine using optically active methylhydroxylaminopropanol compound as an intermediate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2042346A1 (en) * 1990-05-17 1991-11-18 Michael Alexander Staszak Chiral synthesis of 1-aryl-3-aminopropan-1-ols

Also Published As

Publication number Publication date
PL370432A1 (en) 2005-05-30
WO2003070720A1 (en) 2003-08-28
HRP20040744A2 (en) 2004-12-31
DE10207586A1 (de) 2003-09-11
EP1476439A1 (en) 2004-11-17
US20050171360A1 (en) 2005-08-04
JP2005519077A (ja) 2005-06-30
KR20040096593A (ko) 2004-11-16
CA2477082A1 (en) 2003-08-28
AU2003206800A1 (en) 2003-09-09

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