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IL162527A0 - Novel fluorene carboxylic acid esters, methods forthe production thereof, and use of the same as pharmaceuticals - Google Patents

Novel fluorene carboxylic acid esters, methods forthe production thereof, and use of the same as pharmaceuticals

Info

Publication number
IL162527A0
IL162527A0 IL16252703A IL16252703A IL162527A0 IL 162527 A0 IL162527 A0 IL 162527A0 IL 16252703 A IL16252703 A IL 16252703A IL 16252703 A IL16252703 A IL 16252703A IL 162527 A0 IL162527 A0 IL 162527A0
Authority
IL
Israel
Prior art keywords
pharmaceuticals
carboxylic acid
same
acid esters
forthe production
Prior art date
Application number
IL16252703A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL162527A0 publication Critical patent/IL162527A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • C07D451/12Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/06Anti-spasmodics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • C07D451/10Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL16252703A 2002-01-31 2003-01-21 Novel fluorene carboxylic acid esters, methods forthe production thereof, and use of the same as pharmaceuticals IL162527A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10203741A DE10203741A1 (de) 2002-01-31 2002-01-31 Neue Fluorencarbonsäureester, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
PCT/EP2003/000534 WO2003064419A1 (fr) 2002-01-31 2003-01-21 Nouveaux esters d'acide carboxylique de fluorene, procede permettant de les produire et leur utilisation comme medicaments

Publications (1)

Publication Number Publication Date
IL162527A0 true IL162527A0 (en) 2005-11-20

Family

ID=27588159

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16252703A IL162527A0 (en) 2002-01-31 2003-01-21 Novel fluorene carboxylic acid esters, methods forthe production thereof, and use of the same as pharmaceuticals

Country Status (28)

Country Link
EP (2) EP1561751A1 (fr)
JP (1) JP4484522B2 (fr)
KR (1) KR100950869B1 (fr)
CN (1) CN100348598C (fr)
AR (1) AR038379A1 (fr)
AT (1) ATE299880T1 (fr)
AU (1) AU2003210172C1 (fr)
BR (1) BR0307294A (fr)
CA (1) CA2472149C (fr)
DE (2) DE10203741A1 (fr)
EA (1) EA006966B1 (fr)
EC (1) ECSP045209A (fr)
ES (1) ES2245443T3 (fr)
HR (1) HRP20040690B1 (fr)
IL (1) IL162527A0 (fr)
ME (1) MEP43408A (fr)
MX (1) MXPA04007245A (fr)
MY (1) MY134582A (fr)
NO (1) NO328929B1 (fr)
NZ (1) NZ534784A (fr)
PE (1) PE20031029A1 (fr)
PL (1) PL209037B1 (fr)
PT (1) PT1472251E (fr)
RS (1) RS50918B (fr)
TW (1) TWI352077B (fr)
UA (1) UA78544C2 (fr)
UY (1) UY27633A1 (fr)
WO (1) WO2003064419A1 (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1651208A1 (fr) * 2003-07-28 2006-05-03 Boehringer Ingelheim International GmbH Medicaments comprenant des inhibiteurs de pde iv et un nouvel anticholinergique, et leur utilisation pour le traitement de troubles respiratoires
ES2326320T3 (es) * 2003-07-28 2009-10-07 Boehringer Ingelheim International Gmbh Medicamentos para inhalacion que comprenden esteroides y nuevo ester del acido fluorencarboxilico.
EP1651221B1 (fr) * 2003-07-28 2009-01-14 Boehringer Ingelheim International Gmbh Medicaments pour inhalation comportant des agents a activite betamimetique et anticholinergique
EP1651224B1 (fr) * 2003-07-31 2011-10-05 Boehringer Ingelheim International GmbH Medicaments pour inhalation comportant un agent a activite anticholinergique et un betamimetique
DE102004001607A1 (de) * 2004-01-09 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen auf der Basis von Scopin- oder Tropensäureestern mit EGFR-Kinase-Hemmern
EP1718301A1 (fr) * 2004-02-20 2006-11-08 Boehringer Ingelheim International GmbH Compositions pharmaceutiques a base d'anticholinergiques et de pegsunercept
US7507745B2 (en) * 2004-02-20 2009-03-24 Boehringer Ingelheim International Gmbh Pharmaceutical compositions based on fluorenecarboxylic acid esters and soluble TNF receptor fusion proteins
DE102004016179A1 (de) * 2004-03-30 2005-10-20 Boehringer Ingelheim Pharma Verbindungen zur Behandlung von proliferativen Prozessen
US20060034776A1 (en) * 2004-08-10 2006-02-16 Boehringer Ingelheim International Gmbh Inhalable medicaments containing a new anticholinergic, corticosteroids, and betamimetics
DE102004038885A1 (de) * 2004-08-10 2006-02-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
ES2322148T3 (es) * 2004-08-11 2009-06-17 BOEHRINGER INGELHEIM PHARMA GMBH &amp; CO. KG Medicamentos que contienen anticolinergicos para el tratamiento en las vias urinarias.
DE102005001297A1 (de) * 2005-01-12 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
WO2006087316A1 (fr) * 2005-02-16 2006-08-24 Boehringer Ingelheim International Gmbh Compositions pharmaceutiques comprenant des anticholinergiques et de l’etiprednol
WO2006094924A2 (fr) * 2005-03-09 2006-09-14 Boehringer Ingelheim International Gmbh Nouvelles compositions pharmaceutiques a base d'anticholinergiques et d'inhibiteurs de pde 5
WO2006128847A2 (fr) * 2005-05-31 2006-12-07 Boehringer Ingelheim International Gmbh Nouvelles combinaisons medicamenteuses pour le traitement de maladies respiratoires
DE102005030733A1 (de) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
US7423146B2 (en) 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
EP2051714B1 (fr) 2006-08-07 2011-04-13 Boehringer Ingelheim International GmbH Combinaisons de médicaments pour le traitement des infections des voies respiratoires
UY30550A1 (es) 2006-08-22 2008-03-31 Boehringer Ingelheim Int Nuevos beta-agonistas enantioméricamente puros, procedimientos para su preparacion y su uso como medicamentos
EP1925296A1 (fr) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Formule de poudre stable contenant un nouveau anticholinergique
EP1997819A1 (fr) * 2007-05-25 2008-12-03 Boehringer Ingelheim Pharma GmbH & Co. KG Procédé destiné à la fabrication d'esters de scopine
ES2569359T3 (es) 2007-07-06 2016-05-10 Vectura Delivery Devices Limited Inhalador
EP2180892A2 (fr) * 2007-07-18 2010-05-05 Boehringer Ingelheim International GmbH Combinaisons contenant telmisartan et un agent anticholinergique comme le tiotropium ou un sel de glycopyrrionium pour le traitement de maladies respiratoires comme le bpco ou l'asthma
EP2082766A1 (fr) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Formation d'une spirale de bande alvéolée
EP2082768A1 (fr) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhalateur
EP2082767A1 (fr) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhalateur
EP2082772A1 (fr) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhalateur
EP2082771A1 (fr) 2008-01-24 2009-07-29 Vectura Delivery Devices Limited Inhalateur
EP2093219A1 (fr) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Forme de sel à énantiomère pur et cristalline d'un bêtamimétique et son utilisation comme médicament
GB0918450D0 (en) 2009-10-21 2009-12-09 Innovata Ltd Composition
CN102876318B (zh) * 2012-09-28 2014-07-16 宁波大学 一种芴羧酸酯荧光材料及其制备方法
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
KR20200067170A (ko) 2017-10-05 2020-06-11 풀크럼 쎄러퓨틱스, 인코포레이티드 FSHD의 치료를 위하여 DUX4 및 하류 유전자 발현을 저감시키는 p38 키나제 저해제

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2221828A (en) * 1936-04-25 1940-11-19 Merck & Co Inc Esters of amino alcohols with 9-hydroxyfluorene-9-carboxylic acid and processes for their production
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
NO328929B1 (no) 2010-06-21
PT1472251E (pt) 2005-10-31
CN100348598C (zh) 2007-11-14
PL209037B1 (pl) 2011-07-29
JP2005516067A (ja) 2005-06-02
EP1561751A1 (fr) 2005-08-10
MEP43408A (en) 2011-02-10
DE10203741A1 (de) 2003-08-14
EP1472251B1 (fr) 2005-07-20
CA2472149A1 (fr) 2003-08-07
ECSP045209A (es) 2004-09-28
RS50918B (sr) 2010-08-31
HK1082376A1 (en) 2006-05-04
JP4484522B2 (ja) 2010-06-16
KR20040081166A (ko) 2004-09-20
MXPA04007245A (es) 2004-10-29
CN1625557A (zh) 2005-06-08
AR038379A1 (es) 2005-01-12
HRP20040690A2 (en) 2005-10-31
MY134582A (en) 2007-12-31
RS65604A (sr) 2006-12-15
KR100950869B1 (ko) 2010-04-06
EP1472251A1 (fr) 2004-11-03
TWI352077B (en) 2011-11-11
ES2245443T3 (es) 2006-01-01
EA006966B1 (ru) 2006-06-30
PL369396A1 (en) 2005-04-18
TW200302817A (en) 2003-08-16
NO20043612L (no) 2004-08-30
HRP20040690B1 (en) 2012-09-30
WO2003064419A1 (fr) 2003-08-07
EA200400878A1 (ru) 2005-02-24
DE50300813D1 (de) 2005-08-25
NZ534784A (en) 2005-08-26
CA2472149C (fr) 2011-01-11
AU2003210172B2 (en) 2009-04-02
BR0307294A (pt) 2004-12-21
ATE299880T1 (de) 2005-08-15
AU2003210172C1 (en) 2009-09-24
UY27633A1 (es) 2003-08-29
UA78544C2 (uk) 2007-04-10
PE20031029A1 (es) 2004-01-27

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