IL161348A0 - Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]piperidine derivatives and their use as selective non-peptide delta opioid agonists - Google Patents

Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]piperidine derivatives and their use as selective non-peptide delta opioid agonists

Info

Publication number: IL161348A0
Authority: IL; Israel
Prior art keywords: imidazol; phenyl; piperidine derivatives; novel substituted; opioid agonists
Prior art date: 2001-10-15

Application number

IL16134802A

Other languages

English (en)

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-15

Filing date

2002-10-10

Publication date

2004-09-27

2002-10-10 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2004-09-27 Publication of IL161348A0 publication Critical patent/IL161348A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Nutrition Science (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL16134802A 2001-10-15 2002-10-10 Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]piperidine derivatives and their use as selective non-peptide delta opioid agonists IL161348A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01203926		2001-10-15
PCT/EP2002/011372 WO2003033486A1 (en)	2001-10-15	2002-10-10	Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]-piperidine derivatives and their use as selective non-peptide delta opioid agonists

Publications (1)

Publication Number	Publication Date
IL161348A0 true IL161348A0 (en)	2004-09-27

Family

ID=8181080

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL16134802A IL161348A0 (en)	2001-10-15	2002-10-10	Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]piperidine derivatives and their use as selective non-peptide delta opioid agonists
IL161348A IL161348A (en)	2001-10-15	2004-04-13	Substituted 4- phenyl-4-[1h - imidazol-2-yl] piperidine derivatives and their use for the preparation of pharmaceutical compositions

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL161348A IL161348A (en)	2001-10-15	2004-04-13	Substituted 4- phenyl-4-[1h - imidazol-2-yl] piperidine derivatives and their use for the preparation of pharmaceutical compositions

Country Status (26)

Country	Link
US (2)	US7282508B2 (zh)
EP (1)	EP1438304B1 (zh)
JP (1)	JP4417108B2 (zh)
KR (1)	KR100898562B1 (zh)
CN (1)	CN100354273C (zh)
AR (1)	AR037506A1 (zh)
AT (1)	ATE347549T1 (zh)
AU (1)	AU2002346994B2 (zh)
BR (1)	BR0213327A (zh)
CA (1)	CA2462953C (zh)
CY (1)	CY1106356T1 (zh)
DE (1)	DE60216627T2 (zh)
EA (1)	EA006507B1 (zh)
ES (1)	ES2278065T3 (zh)
HR (1)	HRP20040324A2 (zh)
HU (1)	HUP0600447A3 (zh)
IL (2)	IL161348A0 (zh)
MX (1)	MXPA04003479A (zh)
MY (1)	MY137356A (zh)
NO (1)	NO327602B1 (zh)
NZ (1)	NZ531679A (zh)
PL (1)	PL367967A1 (zh)
PT (1)	PT1438304E (zh)
UA (1)	UA76224C2 (zh)
WO (1)	WO2003033486A1 (zh)
ZA (1)	ZA200402818B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL370371A1 (en) *	2001-10-15	2005-05-16	Janssen Pharmaceutica N.V.	Substituted 4-phenyl-4-(1h-imidazol-2-yl)-piperidine derivatives for reducing ischaemic damage
TW200403058A (en) *	2002-04-19	2004-03-01	Bristol Myers Squibb Co	Heterocyclo inhibitors of potassium channel function
EP1501825A2 (en)	2002-05-08	2005-02-02	Neurogen Corporation	Substituted imidazolylmethyl pyridine and pyrazine derivatives: gaba a receptor ligands
US20060128752A1 (en) *	2002-07-03	2006-06-15	Giuseppe Alvaro	Chemical compounds
CL2004000754A1 (es) *	2003-04-11	2005-02-25	Janssen Pharmaceutica Nv	Uso de compuestos derivados de 4-fenil-4-(1h-imidazol-2-il)piperidina, como agonistas delta-opioides no peptidicos, para preparar un medicamento util en prevenir o tratar trastornos del sistema nervioso central.
AU2004278414B2 (en)	2003-10-01	2012-05-24	Adolor Corporation	Spirocyclic heterocyclic derivatives and methods of their use
CN1950342B (zh) *	2004-03-15	2012-09-26	詹森药业有限公司	作为阿片受体调节剂的新化合物
AU2013205089B2 (en) *	2004-03-15	2013-12-19	Janssen Pharmaceutica, N.V.	Novel compounds as opioid receptor modulators
US7598261B2 (en)	2005-03-31	2009-10-06	Adolor Corporation	Spirocyclic heterocyclic derivatives and methods of their use
US7576207B2 (en)	2006-04-06	2009-08-18	Adolor Corporation	Spirocyclic heterocyclic derivatives and methods of their use
WO2008033299A2 (en)	2006-09-12	2008-03-20	Adolor Corporation	Use of n-containing spirocompounds for the enhancement of cognitive function
IT1396951B1 (it)	2009-12-18	2012-12-20	Neuroscienze Pharmaness S C A R L	Composti farmaceutici
US9675587B2 (en)	2013-03-14	2017-06-13	Allergan Holdings Unlimited Company	Opioid receptor modulator dosage formulations
TWI652264B (zh) *	2013-09-26	2019-03-01	東麗股份有限公司	Cyclic amine derivatives and their medical uses
WO2019079578A1 (en)	2017-10-19	2019-04-25	Amgen Inc.	BENZIMIDAZOLE DERIVATIVES AND USES THEREOF
US20240308960A1 (en) *	2021-05-26	2024-09-19	Sumitomo Pharma Co., Ltd.	Phenyl urea derivative

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JP2985322B2 (ja)	1991-03-01	1999-11-29	東レ株式会社	イソキノリン誘導体およびその医薬用途
US5354863A (en) *	1992-01-21	1994-10-11	G. D. Searle & Co.	Opioid agonist compounds
GB9202238D0 (en)	1992-02-03	1992-03-18	Wellcome Found	Compounds
CN1043641C (zh)	1993-08-06	1999-06-16	史密丝克莱恩比彻姆制药股份公司	氢化异喹啉衍生物
US5618934A (en)	1994-05-17	1997-04-08	Merck & Co., Inc.	Boronic acid compound
AU4458996A (en)	1995-01-20	1996-08-07	Nippon Shinyaku Co. Ltd.	Ethylamine derivatives and drugs
IT1307327B1 (it)	1995-09-12	2001-10-30	Smithkline Beecham Spa	Derivati idroisochinolinici sostituiti
TW548271B (en)	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv)	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
DE19805370A1 (de)	1997-03-14	1998-09-17	Gruenenthal Gmbh	Substituierte Aminoverbindungen und ihre Verwendung als analgetisch wirksame Substanzen
GB9709972D0 (en)	1997-05-19	1997-07-09	Pfizer Ltd	Tetrazoles
SI1144411T1 (en) *	1998-12-19	2005-10-31	Janssen Pharmaceutica N.V.	Antihistaminic spiro compounds
EP1038872A1 (en) *	1999-02-22	2000-09-27	Pfizer Products Inc.	4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands
JP2005231995A (ja)	1999-12-22	2005-09-02	Meiji Seika Kaisha Ltd	オピオイドδ受容体アゴニスト／アンタゴニストとして有用なスピロ化合物

2002
- 2002-10-10 UA UA20040503667A patent/UA76224C2/uk unknown
- 2002-10-10 EP EP02782881A patent/EP1438304B1/en not_active Expired - Lifetime
- 2002-10-10 HR HR20040324A patent/HRP20040324A2/xx not_active Application Discontinuation
- 2002-10-10 AU AU2002346994A patent/AU2002346994B2/en not_active Ceased
- 2002-10-10 US US10/491,379 patent/US7282508B2/en not_active Expired - Fee Related
- 2002-10-10 DE DE60216627T patent/DE60216627T2/de not_active Expired - Lifetime
- 2002-10-10 IL IL16134802A patent/IL161348A0/xx unknown
- 2002-10-10 ES ES02782881T patent/ES2278065T3/es not_active Expired - Lifetime
- 2002-10-10 CA CA2462953A patent/CA2462953C/en not_active Expired - Lifetime
- 2002-10-10 AT AT02782881T patent/ATE347549T1/de active
- 2002-10-10 WO PCT/EP2002/011372 patent/WO2003033486A1/en not_active Ceased
- 2002-10-10 PT PT02782881T patent/PT1438304E/pt unknown
- 2002-10-10 KR KR1020047002381A patent/KR100898562B1/ko not_active Expired - Fee Related
- 2002-10-10 NZ NZ531679A patent/NZ531679A/en not_active IP Right Cessation
- 2002-10-10 MX MXPA04003479A patent/MXPA04003479A/es active IP Right Grant
- 2002-10-10 PL PL02367967A patent/PL367967A1/xx unknown
- 2002-10-10 CN CNB028203275A patent/CN100354273C/zh not_active Expired - Fee Related
- 2002-10-10 BR BR0213327-0A patent/BR0213327A/pt not_active IP Right Cessation
- 2002-10-10 EA EA200400545A patent/EA006507B1/ru not_active IP Right Cessation
- 2002-10-10 JP JP2003536226A patent/JP4417108B2/ja not_active Expired - Fee Related
- 2002-10-10 HU HU0600447A patent/HUP0600447A3/hu unknown
- 2002-10-11 AR ARP020103837A patent/AR037506A1/es unknown
- 2002-10-11 MY MYPI20023800A patent/MY137356A/en unknown
2004
- 2004-04-13 ZA ZA2004/02818A patent/ZA200402818B/en unknown
- 2004-04-13 IL IL161348A patent/IL161348A/en not_active IP Right Cessation
- 2004-04-22 NO NO20041666A patent/NO327602B1/no not_active IP Right Cessation
2007
- 2007-03-06 CY CY20071100311T patent/CY1106356T1/el unknown
- 2007-05-25 US US11/753,830 patent/US20080096925A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PL367967A1 (en)	2005-03-07
EA006507B1 (ru)	2005-12-29
CN1568321A (zh)	2005-01-19
DE60216627T2 (de)	2007-09-20
ZA200402818B (en)	2005-06-29
JP4417108B2 (ja)	2010-02-17
US20040260096A1 (en)	2004-12-23
US20080096925A1 (en)	2008-04-24
BR0213327A (pt)	2004-10-13
NZ531679A (en)	2005-02-25
CA2462953C (en)	2011-01-04
NO327602B1 (no)	2009-08-31
HUP0600447A3 (en)	2008-03-28
WO2003033486A1 (en)	2003-04-24
NO20041666L (no)	2004-04-22
DE60216627D1 (de)	2007-01-18
ES2278065T3 (es)	2007-08-01
MY137356A (en)	2009-01-30
CY1106356T1 (el)	2011-10-12
EA200400545A1 (ru)	2004-08-26
KR20050035121A (ko)	2005-04-15
IL161348A (en)	2010-11-30
UA76224C2 (en)	2006-07-17
EP1438304A1 (en)	2004-07-21
MXPA04003479A (es)	2004-07-30
AR037506A1 (es)	2004-11-17
KR100898562B1 (ko)	2009-05-20
PT1438304E (pt)	2007-03-30
ATE347549T1 (de)	2006-12-15
EP1438304B1 (en)	2006-12-06
HUP0600447A2 (en)	2006-09-28
HRP20040324A2 (en)	2005-04-30
CN100354273C (zh)	2007-12-12
JP2005505625A (ja)	2005-02-24
US7282508B2 (en)	2007-10-16
CA2462953A1 (en)	2003-04-24
AU2002346994B2 (en)	2007-09-06

Publication	Publication Date	Title
IL161348A0 (en)	2004-09-27	Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]piperidine derivatives and their use as selective non-peptide delta opioid agonists
IL159697A0 (en)	2004-06-20	Substituted anilinic piperidines as mch selective antagonists
IL145742A0 (en)	2002-07-25	Piperidine derivatives useful as ccr5 antagonists
IL181957A0 (en)	2009-02-11	Pyrimidine-4-one derivatives as ldl-pla2 inhibitors
IL151919A0 (en)	2003-04-10	Imidazopyridine derivatives and triazolpyrimidine derivatives
EP1427415A4 (en)	2005-11-02	COMPOUNDS CONTAINING LACTAM AND DERIVATIVES AS FACTOR XA INHIBITORS
IL160060A0 (en)	2004-06-20	Piperidine derivatives useful as ccr5 antagonists
AU7392101A (en)	2001-10-23	8-quinolinxanthine and 8-isoquinolinxanthine derivatives as pde 5 inhibitors
AU2001242744A1 (en)	2001-12-13	Diphenylalkylamine derivatives useful as opioid delta receptor ligands
AU2002227919A1 (en)	2002-06-03	Novel sulfonamide-substituted pyrazolopyridine derivatives
IL151093A0 (en)	2003-04-10	Derivatives of quinoline as alpha-2 antagonists
PL368732A1 (en)	2005-04-04	C-14 oxidation of morphine derivatives
AU2003297608A1 (en)	2004-06-18	High concentration formulations of opioids and opioid derivatives
IL158056A0 (en)	2004-03-28	Chemical derivatives and their use as anti-telomerase agent
GB0026578D0 (en)	2000-12-13	Heterocyclic derivatives useful as pharmaceutical agents
HRP20040671A2 (en)	2005-08-31	Imidazoquinoline derivatives
AU2001271018A1 (en)	2002-01-14	Gpr14 antagonist
AU2002224772A1 (en)	2002-04-22	Morphinoid derivatives as delta-opioid agonists and antagonists
IL150862A0 (en)	2003-02-12	Heterocyclic amide derivatives
AU2002352388A1 (en)	2003-06-30	N-aroyl cyclic amine derivatives and their use as orxin receptor antagonist
IL142810A0 (en)	2002-03-10	Pharmaceutical uses for fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
HK1085734A (zh)	2006-09-01	二芳基亚甲基哌啶衍生物及其作为δ阿片受体激动剂的用途
GB0203197D0 (en)	2002-03-27	Delta opioid agonists
HK1056170A (zh)	2004-02-06	吡嗪喹恶啉衍生物作为血清基显效药及拮抗药
GB0104583D0 (en)	2001-04-11	Piperidine derivatives