IL157167A0 - Sensitization of chemotherapeutic agent resistant neoplastic cells with reovirus - Google Patents
Sensitization of chemotherapeutic agent resistant neoplastic cells with reovirusInfo
- Publication number
- IL157167A0 IL157167A0 IL15716702A IL15716702A IL157167A0 IL 157167 A0 IL157167 A0 IL 157167A0 IL 15716702 A IL15716702 A IL 15716702A IL 15716702 A IL15716702 A IL 15716702A IL 157167 A0 IL157167 A0 IL 157167A0
- Authority
- IL
- Israel
- Prior art keywords
- reovirus
- sensitization
- chemotherapeutic agent
- neoplastic cells
- agent resistant
- Prior art date
Links
- 241000702263 Reovirus sp. Species 0.000 title 1
- 206010070834 Sensitisation Diseases 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229940127089 cytotoxic agent Drugs 0.000 title 1
- 210000005170 neoplastic cell Anatomy 0.000 title 1
- 230000008313 sensitization Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/765—Reovirus; Rotavirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
- C12N2720/12232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Inorganic Chemistry (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27036301P | 2001-02-20 | 2001-02-20 | |
| PCT/CA2002/000201 WO2002066040A2 (en) | 2001-02-20 | 2002-02-19 | Sensitization of chemotherapeutic agent resistant neoplastic cells with reovirus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL157167A0 true IL157167A0 (en) | 2004-02-08 |
Family
ID=23031034
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15716702A IL157167A0 (en) | 2001-02-20 | 2002-02-19 | Sensitization of chemotherapeutic agent resistant neoplastic cells with reovirus |
| IL157167A IL157167A (en) | 2001-02-20 | 2003-07-30 | Reovirus medicinal product and antitumor for the treatment or prevention of cancer and commercial packaging containing the reovirus and antitumor |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL157167A IL157167A (en) | 2001-02-20 | 2003-07-30 | Reovirus medicinal product and antitumor for the treatment or prevention of cancer and commercial packaging containing the reovirus and antitumor |
Country Status (15)
| Country | Link |
|---|---|
| US (5) | US7264798B2 (es) |
| EP (2) | EP2314301A3 (es) |
| JP (3) | JP4951194B2 (es) |
| AR (1) | AR035227A1 (es) |
| AT (1) | ATE516807T1 (es) |
| AU (2) | AU2002234453B2 (es) |
| BR (1) | BR0207691A (es) |
| CA (1) | CA2437468C (es) |
| DK (1) | DK1361884T3 (es) |
| ES (1) | ES2367768T3 (es) |
| IL (2) | IL157167A0 (es) |
| MX (1) | MXPA03007486A (es) |
| NZ (2) | NZ527399A (es) |
| WO (1) | WO2002066040A2 (es) |
| ZA (1) | ZA200305875B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
| US6136307A (en) | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
| AR035227A1 (es) | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
| WO2003094939A1 (en) | 2002-05-10 | 2003-11-20 | Oncolytics Biotech Inc. | Sensitization of neoplastic cells to radiation therapy with oncolytic viruses |
| WO2004096126A2 (en) * | 2003-04-25 | 2004-11-11 | Wellstat Biologics Corporation | Treating hepatocellular carcinomas using therapeutic viruses |
| EP1644492B1 (en) | 2003-06-18 | 2009-01-07 | Genelux Corporation | Modified recombinant vaccinia viruses, uses thereof |
| CA2562904C (en) * | 2004-04-27 | 2013-07-02 | Wellstat Biologics Corporation | Cancer treatment using viruses and camptothecins |
| WO2005112966A1 (en) * | 2004-05-21 | 2005-12-01 | Orison Biotechnology Inc. | Combined therapy with a herbal extract and a reovirus for killing neoplastic cells in a subject |
| KR20080039344A (ko) * | 2005-07-14 | 2008-05-07 | 웰스테트 바이올로직스 코포레이션 | 바이러스, 플루오로피리미딘 및 캄토테신을 이용한 암치료방법 |
| US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
| WO2007099401A2 (en) * | 2005-08-01 | 2007-09-07 | University Technologies International, Inc. | Oncolytic attenuated reoviruses for treatment of proliferative disorders |
| ES2335308T3 (es) * | 2005-11-24 | 2010-03-24 | AICURIS GMBH & CO. KG | Parapoxvirus en combinacion con agentes quimioterapeuticos clasicos como bioquimoteparia para el tratamiento del cancer. |
| WO2008100292A2 (en) | 2006-10-16 | 2008-08-21 | Genelux Corporation | Modified vaccinia virus strains for use in diagnostic and therapeutic methods |
| US8168661B2 (en) * | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8178564B2 (en) * | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US20110033528A1 (en) * | 2009-08-05 | 2011-02-10 | Poniard Pharmaceuticals, Inc. | Stabilized picoplatin oral dosage form |
| US10369171B2 (en) | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
| WO2008150496A2 (en) * | 2007-05-31 | 2008-12-11 | Genelux Corporation | Assay for sensitivity to chemotherapeutic agents |
| US20100260832A1 (en) * | 2007-06-27 | 2010-10-14 | Poniard Pharmaceuticals, Inc. | Combination therapy for ovarian cancer |
| TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
| JP2010533718A (ja) * | 2007-07-18 | 2010-10-28 | ジェネラックス・コーポレイション | 腫瘍溶解性ウイルス治療に付随する副作用の処置もしくは改善用医薬の製造における化学治療剤の使用 |
| AU2008316276A1 (en) * | 2007-10-22 | 2009-04-30 | Oncolytics Biotech Inc. | Treatment regime for proliferative disorders |
| CN102006875A (zh) * | 2008-02-08 | 2011-04-06 | 帕纳德制药公司 | 吡铂和贝伐单抗治疗结直肠癌的用途 |
| EP2300023A2 (en) * | 2008-05-16 | 2011-03-30 | Genelux Corporation | Microorganisms for preventing and treating neoplasms accompanying cellular therapy |
| KR101585702B1 (ko) * | 2008-05-22 | 2016-01-15 | 제일약품주식회사 | 종양파괴 바이러스 요법에 대한 과다증식성 세포의 종양 억제인자-기초된 민감성 |
| EP2296679A4 (en) * | 2008-05-27 | 2012-03-21 | Oncolytics Biotech Inc | SUPPRESSION OF PRODUCTION OF PRO-INFLAMMATORY CYTOKINES DURING ONCOLYTIC REOVIRUS THERAPY |
| EP2296678A4 (en) * | 2008-05-27 | 2012-03-21 | Oncolytics Biotech Inc | MODULATION OF INTERSTITIAL PRESSURE AND ONCOLYTIC VIRUS RELIEF AND DISTRIBUTION |
| WO2013163724A1 (en) * | 2012-04-30 | 2013-11-07 | Oncolytics Biotech Inc. | Protecting modified viruses from neutralizing antibodies using the reovirus sigma 1 protein |
| MX389560B (es) | 2014-10-24 | 2025-03-20 | Calidi Biotherapeutics Nevada Inc | Enfoque de inmunoterapias de combinación para el tratamiento del cancer. |
| CN104881181B (zh) * | 2015-05-27 | 2019-07-26 | 联想(北京)有限公司 | 显示方法及电子设备 |
| CA3177862A1 (en) | 2018-11-06 | 2020-05-14 | Calidi Biotherapeutics, Inc. | Enhanced systems for cell-mediated oncolytic viral therapy |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0931830B1 (en) | 1993-02-16 | 2001-03-07 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and phophylaxis of neoplasia |
| WO1994025627A1 (en) | 1993-04-30 | 1994-11-10 | Lorence Robert M | Methods of treating and detecting cancer using viruses |
| US5776743A (en) | 1994-09-06 | 1998-07-07 | La Jolla Cancer Research Foundation | Method of sensitizing tumor cells with adenovirus E1A |
| US6136307A (en) | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
| US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
| US6110461A (en) | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
| NZ503664A (en) | 1997-10-09 | 2002-08-28 | Pro Virus Inc | A method for purifying an RNA virus comprising generating a clonal virus and purifying the clonal virus by ultracentrifugation without pelleting |
| US6428968B1 (en) * | 1999-03-15 | 2002-08-06 | The Trustees Of The University Of Pennsylvania | Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject |
| WO2001035970A1 (en) * | 1999-11-12 | 2001-05-25 | Oncolytics Biotech Inc. | Viruses for the treatment of cellular proliferative disorders |
| AR035227A1 (es) * | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
| US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
-
2002
- 2002-02-12 AR ARP020100466A patent/AR035227A1/es unknown
- 2002-02-15 US US10/076,074 patent/US7264798B2/en not_active Expired - Lifetime
- 2002-02-19 WO PCT/CA2002/000201 patent/WO2002066040A2/en not_active Ceased
- 2002-02-19 EP EP10013901A patent/EP2314301A3/en not_active Withdrawn
- 2002-02-19 DK DK02701122.0T patent/DK1361884T3/da active
- 2002-02-19 AU AU2002234453A patent/AU2002234453B2/en not_active Expired
- 2002-02-19 JP JP2002565598A patent/JP4951194B2/ja not_active Expired - Lifetime
- 2002-02-19 NZ NZ527399A patent/NZ527399A/en unknown
- 2002-02-19 EP EP02701122A patent/EP1361884B1/en not_active Expired - Lifetime
- 2002-02-19 ES ES02701122T patent/ES2367768T3/es not_active Expired - Lifetime
- 2002-02-19 IL IL15716702A patent/IL157167A0/xx unknown
- 2002-02-19 NZ NZ537709A patent/NZ537709A/en unknown
- 2002-02-19 CA CA002437468A patent/CA2437468C/en not_active Expired - Lifetime
- 2002-02-19 AT AT02701122T patent/ATE516807T1/de not_active IP Right Cessation
- 2002-02-19 BR BR0207691-8A patent/BR0207691A/pt not_active IP Right Cessation
- 2002-02-19 MX MXPA03007486A patent/MXPA03007486A/es active IP Right Grant
-
2003
- 2003-07-30 ZA ZA200305875A patent/ZA200305875B/en unknown
- 2003-07-30 IL IL157167A patent/IL157167A/en active IP Right Grant
-
2007
- 2007-05-31 US US11/809,293 patent/US7608257B2/en not_active Expired - Lifetime
- 2007-08-16 AU AU2007207860A patent/AU2007207860B2/en not_active Expired
-
2008
- 2008-02-18 JP JP2008036723A patent/JP2008120837A/ja not_active Withdrawn
-
2009
- 2009-09-08 US US12/555,453 patent/US7964187B2/en not_active Expired - Fee Related
-
2011
- 2011-05-17 US US13/109,631 patent/US20110243890A1/en not_active Abandoned
-
2012
- 2012-01-13 JP JP2012005027A patent/JP2012072192A/ja active Pending
- 2012-09-24 US US13/625,259 patent/US8658158B2/en not_active Expired - Lifetime
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