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IL155937A0 - Imidazole and benzimidazole derivatives and pharmaceutical compositions containing the same - Google Patents

Imidazole and benzimidazole derivatives and pharmaceutical compositions containing the same

Info

Publication number
IL155937A0
IL155937A0 IL15593701A IL15593701A IL155937A0 IL 155937 A0 IL155937 A0 IL 155937A0 IL 15593701 A IL15593701 A IL 15593701A IL 15593701 A IL15593701 A IL 15593701A IL 155937 A0 IL155937 A0 IL 155937A0
Authority
IL
Israel
Prior art keywords
imidazole
same
pharmaceutical compositions
compositions containing
benzimidazole derivatives
Prior art date
Application number
IL15593701A
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of IL155937A0 publication Critical patent/IL155937A0/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
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    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
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  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
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IL15593701A 2000-11-21 2001-11-19 Imidazole and benzimidazole derivatives and pharmaceutical compositions containing the same IL155937A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25225200P 2000-11-21 2000-11-21
PCT/US2001/047688 WO2002042278A2 (en) 2000-11-21 2001-11-19 Imidazole and benzimidazole caspase inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
IL155937A0 true IL155937A0 (en) 2003-12-23

Family

ID=22955229

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15593701A IL155937A0 (en) 2000-11-21 2001-11-19 Imidazole and benzimidazole derivatives and pharmaceutical compositions containing the same

Country Status (27)

Country Link
US (1) US7205327B2 (en)
EP (1) EP1341767B1 (en)
JP (2) JP4349802B2 (en)
KR (1) KR20040020042A (en)
CN (1) CN1298707C (en)
AP (1) AP2003002811A0 (en)
AT (1) ATE359274T1 (en)
AU (1) AU2002232541A1 (en)
BG (1) BG107841A (en)
BR (1) BR0115546A (en)
CA (1) CA2429630A1 (en)
CO (1) CO7250442A2 (en)
CZ (1) CZ20031730A3 (en)
DE (1) DE60127860T2 (en)
EA (1) EA200300601A1 (en)
ES (1) ES2283456T3 (en)
HR (1) HRP20030494A2 (en)
HU (1) HUP0301870A3 (en)
IL (1) IL155937A0 (en)
IS (1) IS6822A (en)
MX (1) MXPA03004459A (en)
NO (1) NO20032270L (en)
NZ (1) NZ526420A (en)
PL (1) PL362612A1 (en)
SK (1) SK7792003A3 (en)
WO (1) WO2002042278A2 (en)
ZA (1) ZA200303895B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011350A1 (en) 2000-05-19 2002-01-15 Vertex Pharma PROPHARMAC OF AN INHIBITOR OF INTERLEUKIN-1ß CONVERTER ENZYME (ICE)
AU2003211052A1 (en) * 2002-02-11 2003-09-04 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
EP1499898A2 (en) 2002-04-19 2005-01-26 Vertex Pharmaceuticals Incorporated Regulation of tnf-alpha
US20060217299A1 (en) * 2003-02-24 2006-09-28 Hirofumi Doi Degradation inhibitor for hepatitis b virus x interacting protein
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