IL143092A0 - Stabilization of macrolides - Google Patents

Stabilization of macrolides

Info

Publication number: IL143092A0
Authority: IL; Israel
Prior art keywords: macrolides; stabilization
Prior art date: 1998-12-07

Application number

IL14309299A

Other languages

English (en)

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-07

Filing date

1999-12-06

Publication date

2002-04-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26314797&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL143092(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-12-06 Application filed by Novartis Ag filed Critical Novartis Ag

2002-04-21 Publication of IL143092A0 publication Critical patent/IL143092A0/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)

IL14309299A 1998-12-07 1999-12-06 Stabilization of macrolides IL143092A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9826882.4A GB9826882D0 (en)	1998-12-07	1998-12-07	Organic compounds
GBGB9904934.8A GB9904934D0 (en)	1998-12-07	1999-03-04	Organic compounds
PCT/EP1999/009521 WO2000033878A2 (en)	1998-12-07	1999-12-06	Stabilization of macrolides

Publications (1)

Publication Number	Publication Date
IL143092A0 true IL143092A0 (en)	2002-04-21

Family

ID=26314797

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14309299A IL143092A0 (en)	1998-12-07	1999-12-06	Stabilization of macrolides

Country Status (38)

Country	Link
US (5)	US6605613B2 (cs)
EP (4)	EP2279751A3 (cs)
JP (3)	JP3805625B2 (cs)
KR (2)	KR100695834B1 (cs)
CN (2)	CN1876657B (cs)
AR (3)	AR026102A1 (cs)
AT (1)	ATE365051T1 (cs)
AU (1)	AU759219B2 (cs)
BE (1)	BE1012869A3 (cs)
BR (1)	BR9915986A (cs)
CA (3)	CA2732620C (cs)
CO (1)	CO4980847A1 (cs)
CY (1)	CY1106870T1 (cs)
CZ (2)	CZ302210B6 (cs)
DE (1)	DE69936352T3 (cs)
DK (1)	DK1137439T4 (cs)
ES (1)	ES2288033T5 (cs)
FR (1)	FR2786771B1 (cs)
GB (2)	GB9826882D0 (cs)
HK (1)	HK1038889B (cs)
HU (2)	HU230174B1 (cs)
ID (1)	ID29250A (cs)
IL (1)	IL143092A0 (cs)
IT (1)	IT1319701B1 (cs)
MY (2)	MY120594A (cs)
NO (2)	NO332698B1 (cs)
NZ (2)	NZ511936A (cs)
PE (1)	PE20001333A1 (cs)
PL (2)	PL196627B1 (cs)
PT (1)	PT1137439E (cs)
RU (1)	RU2243769C2 (cs)
SG (1)	SG151072A1 (cs)
SI (1)	SI1137439T2 (cs)
SK (2)	SK286688B6 (cs)
TR (2)	TR200201428T2 (cs)
TW (2)	TWI248938B (cs)
WO (1)	WO2000033878A2 (cs)
ZA (1)	ZA200104360B (cs)

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US20070032853A1 (en)	2002-03-27	2007-02-08	Hossainy Syed F	40-O-(2-hydroxy)ethyl-rapamycin coated stent
US7452692B2 (en)	2002-02-13	2008-11-18	Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság	Method for extracting a macrolide from biomatter
HRP20040765A2 (en)	2002-02-13	2005-02-28	Biogal Gyogyszergyar Rt.	Method for extracting a macrolide from biomatter
TWI307277B (en) *	2002-07-30	2009-03-11	Wyeth Corp	Parenteral formulations
ES2229975T1 (es)	2003-03-31	2005-05-01	Teva Gyogyszergyar Reszvenytarsasag	Cristalizacion y purificacion de macrolidos.
US20050118344A1 (en)	2003-12-01	2005-06-02	Pacetti Stephen D.	Temperature controlled crimping
PL1558622T3 (pl)	2003-07-24	2008-06-30	Teva Gyogyszergyar Zartkoerueen Muekoedoe Reszvenytarsasag	Sposób oczyszczania makrolidów
CN1882338A (zh)	2003-09-18	2006-12-20	马库赛特公司	经巩膜递送
US9114198B2 (en) *	2003-11-19	2015-08-25	Advanced Cardiovascular Systems, Inc.	Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
KR20060126701A (ko) *	2003-12-10	2006-12-08	애크럭스 디디에스 피티와이 리미티드	경피 또는 국소 약물 전달에 따른 원치않는 효과의치료방법
US8551512B2 (en)	2004-03-22	2013-10-08	Advanced Cardiovascular Systems, Inc.	Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
KR20070083839A (ko) *	2004-09-29	2007-08-24	코디스 코포레이션	안정한 무정형 라파마이신 유사 화합물의 약학적 투약 형태
HUE027352T2 (en)	2005-02-09	2016-09-28	Santen Pharmaceutical Co Ltd	Liquid formulations for the treatment of diseases or conditions
AR058283A1 (es) *	2005-12-07	2008-01-30	Wyeth Corp	Metodos para la preparacion de rapamicina cristalina y para la medicion de la cristalinidad de los compuestos de rapamicina utilizando calorimetria diferencial de barrido
US7700614B2 (en) *	2005-12-14	2010-04-20	Abbott Laboratories	One pot synthesis of tetrazole derivatives of rapamycin
WO2007075621A1 (en) *	2005-12-20	2007-07-05	Wyeth	Control of cci-779 dosage form stability through control of drug substance impurities
BRPI0707612B8 (pt) *	2006-02-09	2021-05-25	Macusight Inc	vaso lacrado e formulações líquidas contidas no mesmo
AU2007230964B2 (en)	2006-03-23	2012-07-19	Santen Pharmaceutical Co., Ltd.	Formulations and methods for vascular permeability-related diseases or conditions
WO2011151704A2 (en)	2010-06-02	2011-12-08	Fresenius Kabi Oncology Ltd.	Stable pharmaceutical compositions of rapamycin esters
CN103025753A (zh) *	2010-06-07	2013-04-03	泰立克公司	晶体盐酸依泽替米贝非溶剂化物
EP2601201B1 (en) *	2010-08-04	2014-09-24	Meril Life Sciences Pvt. Ltd.	Process for preparation of novel 42-0-(heteroalkoxyalkyl) rapamycin compounds with anti-proliferative properties"
CA2818225C (en)	2010-11-19	2016-10-25	Biocon Limited	Processes for preparation of everolimus and intermediates thereof
EP2717884A1 (en)	2011-06-06	2014-04-16	Chevron Phillips Chemical Company LP	Use of metallocene compounds for cancer treatment
WO2013022201A1 (en) *	2011-08-11	2013-02-14	Dong-A Pharm. Co., Ltd.	Process of preparing a stabilized and solubilized formulation of sirolimus derivatives
US9610385B2 (en)	2013-03-07	2017-04-04	Abbott Cardiovascular Systems Inc.	Method of fabricating an implantable medical device comprising a rapamycin derivative
IN2013MU02532A (cs)	2013-07-31	2015-06-26	Sahajanand Medical Technologies Pvt Ltd
CN104721158B (zh) *	2013-12-24	2018-01-30	正大天晴药业集团股份有限公司	一种稳定的依维莫司片剂
CN104892632B (zh) *	2015-06-03	2017-12-26	道中道（菏泽）制药有限公司	一种晶体形式的依维莫司及其制备方法
EP3329916A4 (en)	2015-07-28	2019-03-20	Nippon Kayaku Kabushiki Kaisha	PHARMACEUTICAL COMPOSITION COMPRISING RAPAMYCIN OR A DERIVATIVE THEREOF, AND PROCESS FOR PRODUCING THE SAME
US20190015513A1 (en) *	2015-08-28	2019-01-17	Nippon Kayaku Kabushiki Kaisha	Pharmaceutical composition comprising rapamycin or derivative thereof
EP3351245A4 (en) *	2015-09-18	2019-05-22	Nippon Kayaku Kabushiki Kaisha	PHARMACEUTICAL COMPOSITION COMPRISING RAPAMYCIN OR A DERIVATIVE THEREOF
WO2017129772A1 (en)	2016-01-29	2017-08-03	Xellia Phamaceuticals Aps	Stable pharmaceutical compositions of temsirolimus
WO2017204215A1 (ja)	2016-05-27	2017-11-30	日本化薬株式会社	ラパマイシン又はその誘導体を含有する医薬組成物
KR102051806B1 (ko) *	2018-01-12	2019-12-04	주식회사 종근당	에베로리무스를 포함하는 안정화된 약제학적 제제
CN115667271A (zh) *	2020-03-27	2023-01-31	波士顿科学国际有限公司	用于使药物结晶的方法
JP2023028473A (ja) *	2021-08-19	2023-03-03	日本マイクロバイオファーマ株式会社	エベロリムスの製造方法

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US3996355A (en)	1975-01-02	1976-12-07	American Home Products Corporation	Permanent suspension pharmaceutical dosage form
US4049128A (en)	1976-11-18	1977-09-20	Westinghouse Air Brake Company	Control system for automatic railway car coupler
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JPH04230389A (ja)	1990-07-16	1992-08-19	American Home Prod Corp	ラパマイシン誘導体
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DE69333995T2 (de)	1992-10-13	2006-10-19	Wyeth	Carbamate von Rapamycin
RU2181054C2 (ru) *	1994-11-02	2002-04-10	Новартис Аг	Микроэмульсионный предконцентрат
ES2187660T3 (es)	1995-06-09	2003-06-16	Novartis Ag	Derivados de rapamicina.
BE1009856A5 (fr) *	1995-07-14	1997-10-07	Sandoz Sa	Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
EP0956034B1 (en) *	1996-07-30	2002-08-21	Novartis AG	Pharmaceutical compositions for the treatment of transplant rejection, autoimmune or inflammatory conditions comprising cyclosporin a and 40-0-(2-hydroxyethyl)-rapamycin
US6362264B1 (en) *	1996-12-20	2002-03-26	Ck Witco Corporation	Stabilizer for food contact and medical grade PVC
WO1998033482A1 (en)	1997-02-04	1998-08-06	Abbott Laboratories	Pain reducing parenteral liposome formulation

1998
- 1998-12-07 GB GBGB9826882.4A patent/GB9826882D0/en not_active Ceased
1999
- 1999-03-04 GB GBGB9904934.8A patent/GB9904934D0/en not_active Ceased
- 1999-11-29 CO CO99074905A patent/CO4980847A1/es unknown
- 1999-12-02 IT IT1999MI002520A patent/IT1319701B1/it active
- 1999-12-03 AR ARP990106171A patent/AR026102A1/es active IP Right Grant
- 1999-12-03 PE PE1999001209A patent/PE20001333A1/es not_active IP Right Cessation
- 1999-12-03 FR FR9915256A patent/FR2786771B1/fr not_active Expired - Lifetime
- 1999-12-04 TW TW088121250A patent/TWI248938B/zh not_active IP Right Cessation
- 1999-12-04 TW TW094104943A patent/TWI270550B/zh not_active IP Right Cessation
- 1999-12-06 ID IDW00200101156A patent/ID29250A/id unknown
- 1999-12-06 RU RU2001118266/15A patent/RU2243769C2/ru active
- 1999-12-06 SG SG200302502-0A patent/SG151072A1/en unknown
- 1999-12-06 EP EP10179096A patent/EP2279751A3/en not_active Withdrawn
- 1999-12-06 CN CN2006100798040A patent/CN1876657B/zh not_active Expired - Lifetime
- 1999-12-06 NZ NZ511936A patent/NZ511936A/en not_active IP Right Cessation
- 1999-12-06 HU HU1300289A patent/HU230174B1/hu unknown
- 1999-12-06 BR BR9915986-4A patent/BR9915986A/pt not_active Application Discontinuation
- 1999-12-06 HU HU0104489A patent/HU228939B1/hu unknown
- 1999-12-06 PT PT99959381T patent/PT1137439E/pt unknown
- 1999-12-06 JP JP2000586368A patent/JP3805625B2/ja not_active Expired - Lifetime
- 1999-12-06 TR TR2002/01428T patent/TR200201428T2/xx unknown
- 1999-12-06 CN CNB998141240A patent/CN1261163C/zh not_active Expired - Lifetime
- 1999-12-06 AT AT99959381T patent/ATE365051T1/de active
- 1999-12-06 PL PL348333A patent/PL196627B1/pl unknown
- 1999-12-06 ES ES99959381T patent/ES2288033T5/es not_active Expired - Lifetime
- 1999-12-06 CZ CZ20050170A patent/CZ302210B6/cs not_active IP Right Cessation
- 1999-12-06 CA CA2732620A patent/CA2732620C/en not_active Expired - Lifetime
- 1999-12-06 IL IL14309299A patent/IL143092A0/xx not_active IP Right Cessation
- 1999-12-06 SI SI9930985T patent/SI1137439T2/sl unknown
- 1999-12-06 PL PL380082A patent/PL208854B1/pl unknown
- 1999-12-06 SK SK766-2001A patent/SK286688B6/sk not_active IP Right Cessation
- 1999-12-06 CA CA002651609A patent/CA2651609A1/en not_active Abandoned
- 1999-12-06 DE DE69936352T patent/DE69936352T3/de not_active Expired - Lifetime
- 1999-12-06 KR KR1020017007009A patent/KR100695834B1/ko not_active Expired - Lifetime
- 1999-12-06 SK SK5032-2008A patent/SK287325B6/sk not_active IP Right Cessation
- 1999-12-06 WO PCT/EP1999/009521 patent/WO2000033878A2/en not_active Ceased
- 1999-12-06 DK DK99959381.7T patent/DK1137439T4/da active
- 1999-12-06 TR TR2001/01416T patent/TR200101416T2/xx unknown
- 1999-12-06 EP EP06122628A patent/EP1743657A3/en not_active Ceased
- 1999-12-06 CA CA2351580A patent/CA2351580C/en not_active Expired - Lifetime
- 1999-12-06 AU AU16573/00A patent/AU759219B2/en not_active Expired
- 1999-12-06 EP EP99959381A patent/EP1137439B2/en not_active Expired - Lifetime
- 1999-12-06 EP EP10179099A patent/EP2269651A3/en not_active Withdrawn
- 1999-12-06 CZ CZ20012001A patent/CZ303006B6/cs not_active IP Right Cessation
- 1999-12-06 HK HK02100663.4A patent/HK1038889B/en not_active IP Right Cessation
- 1999-12-06 KR KR1020067017352A patent/KR20060096477A/ko not_active Ceased
- 1999-12-07 MY MYPI99005309A patent/MY120594A/en unknown
- 1999-12-07 BE BE9900799A patent/BE1012869A3/fr not_active IP Right Cessation
- 1999-12-07 MY MYPI20043386A patent/MY127579A/en unknown
2001
- 2001-05-16 NO NO20012424A patent/NO332698B1/no not_active IP Right Cessation
- 2001-05-28 ZA ZA200104360A patent/ZA200104360B/en unknown
- 2001-05-29 US US09/866,977 patent/US6605613B2/en not_active Expired - Lifetime
2003
- 2003-03-21 US US10/393,795 patent/US6852729B2/en not_active Expired - Lifetime
- 2003-08-25 NZ NZ527781A patent/NZ527781A/en not_active IP Right Cessation
2004
- 2004-12-23 US US11/020,860 patent/US7297703B2/en not_active Expired - Lifetime
2005
- 2005-02-28 AR ARP050100744A patent/AR048073A2/es active IP Right Grant
- 2005-04-01 JP JP2005106512A patent/JP5043308B2/ja not_active Expired - Lifetime
- 2005-12-28 JP JP2005378514A patent/JP5165199B2/ja not_active Expired - Lifetime
2006
- 2006-05-04 AR ARP060101807A patent/AR054444A2/es active IP Right Grant
2007
- 2007-09-14 CY CY20071101192T patent/CY1106870T1/el unknown
- 2007-10-11 US US11/973,927 patent/US7572804B2/en not_active Expired - Fee Related
2009
- 2009-07-06 US US12/497,728 patent/US7741338B2/en not_active Expired - Fee Related
2012
- 2012-10-01 NO NO20121113A patent/NO334612B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
FR2786771B1 (fr)	2002-12-27
WO2000033878A2 (en)	2000-06-15
EP1137439A2 (en)	2001-10-04
CN1876657A (zh)	2006-12-13
US20080161334A1 (en)	2008-07-03
GB9826882D0 (en)	1999-01-27
EP2279751A2 (en)	2011-02-02
HUP0104489A3 (en)	2004-05-28
DE69936352T3 (de)	2012-05-03
CA2351580C (en)	2012-03-20
SI1137439T2 (sl)	2012-05-31
ZA200104360B (en)	2002-01-16
TW200540179A (en)	2005-12-16
DE69936352T2 (de)	2008-02-14
DK1137439T4 (da)	2012-03-19
CN1876657B (zh)	2013-01-09
AR048073A2 (es)	2006-03-29
SK7662001A3 (en)	2001-12-03
ITMI992520A0 (it)	1999-12-02
DE69936352D1 (de)	2007-08-02
US7741338B2 (en)	2010-06-22
US20020032213A1 (en)	2002-03-14
JP3805625B2 (ja)	2006-08-02
AR026102A1 (es)	2003-01-29
ES2288033T5 (es)	2012-04-10
US7297703B2 (en)	2007-11-20
CY1106870T1 (el)	2012-09-26
DK1137439T3 (da)	2007-09-10
JP5165199B2 (ja)	2013-03-21
PT1137439E (pt)	2007-09-25
KR20010101128A (ko)	2001-11-14
AU1657300A (en)	2000-06-26
US20030191148A1 (en)	2003-10-09
SK286688B6 (sk)	2009-03-05
HU230174B1 (hu)	2015-09-28
PL196627B1 (pl)	2008-01-31
HK1038889B (en)	2008-01-25
US7572804B2 (en)	2009-08-11
EP1137439B2 (en)	2011-11-23
KR20060096477A (ko)	2006-09-11
ATE365051T1 (de)	2007-07-15
US6852729B2 (en)	2005-02-08
AR054444A2 (es)	2007-06-27
SK287325B6 (sk)	2010-07-07
NZ527781A (en)	2004-11-26
HK1038889A1 (en)	2002-04-04
BE1012869A3 (fr)	2001-04-03
WO2000033878A3 (en)	2000-11-02
BR9915986A (pt)	2001-09-04
ID29250A (id)	2001-08-16
IT1319701B1 (it)	2003-10-27
FR2786771A1 (fr)	2000-06-09
CZ302210B6 (cs)	2010-12-22
ES2288033T3 (es)	2007-12-16
MY120594A (en)	2005-11-30
TR200201428T2 (tr)	2002-12-23
PL348333A1 (en)	2002-05-20
EP1743657A2 (en)	2007-01-17
KR100695834B1 (ko)	2007-03-19
PL208854B1 (pl)	2011-06-30
CA2351580A1 (en)	2000-06-15
EP2269651A3 (en)	2011-03-09
ITMI992520A1 (it)	2001-06-02
EP1743657A3 (en)	2007-03-28
CO4980847A1 (es)	2000-11-27
EP2269651A2 (en)	2011-01-05
RU2243769C2 (ru)	2005-01-10
US20050107418A1 (en)	2005-05-19
GB9904934D0 (en)	1999-04-28
JP2005200429A (ja)	2005-07-28
SI1137439T1 (sl)	2008-06-30
NZ511936A (en)	2003-10-31
TR200101416T2 (tr)	2002-01-21
US6605613B2 (en)	2003-08-12
NO332698B1 (no)	2012-12-10
NO20012424D0 (no)	2001-05-16
JP5043308B2 (ja)	2012-10-10
CZ303006B6 (cs)	2012-02-22
US20090270441A1 (en)	2009-10-29
EP1137439B1 (en)	2007-06-20
AU759219B2 (en)	2003-04-10
CA2651609A1 (en)	2000-06-15
TWI248938B (en)	2006-02-11
SG151072A1 (en)	2009-06-29
JP2002531527A (ja)	2002-09-24
CA2732620C (en)	2013-08-06
CN1374872A (zh)	2002-10-16
MY127579A (en)	2006-12-29
NO20012424L (no)	2001-05-16
JP2006111637A (ja)	2006-04-27
HU228939B1 (en)	2013-07-29
TWI270550B (en)	2007-01-11
PE20001333A1 (es)	2000-12-12
CA2732620A1 (en)	2000-06-15
NO334612B1 (no)	2014-04-22
CZ20012001A3 (cs)	2001-09-12
NO20121113L (no)	2001-05-16
EP2279751A3 (en)	2011-02-16
HUP0104489A2 (hu)	2002-03-28
CN1261163C (zh)	2006-06-28

Publication	Publication Date	Title
IL143092A0 (en)	2002-04-21	Stabilization of macrolides
IL137024A0 (en)	2001-06-14	Novel macrolides
PL341647A1 (en)	2001-04-23	Novel derivatives of erythromycin
PL346544A1 (en)	2002-02-11	Crystalline forms of eto2
PL340290A1 (en)	2001-01-29	2-halogeno-6-0-substituted derivatives of ketolide
TW364383U (en)	1999-07-11	Improvement on structure of wrist-ball
SG83724A1 (en)	2001-10-16	Novel polyene macrolide compounds and uses
PL342733A1 (en)	2001-07-02	Biocement of improved properties
TW399818U (en)	2000-07-21	Structure of connector
HUP9902855A3 (en)	2001-04-28	Preparation of sterol- and stanol-esters
AU2003200370A1 (en)	2003-04-17	Stabilization of macrolides
TW371522U (en)	1999-10-01	Card-rejection mechanism of connector
AU3898299A (en)	1999-11-29	Thermal treatment wall
TW398188U (en)	2000-07-11	Improved structure of de-hooker
TW354479U (en)	1999-03-11	Improvement of earpick
GB2346031B (en)	2003-06-25	Adaption of cabling
GB9914540D0 (en)	1999-08-25	Colonicure or RKH colone
TW355988U (en)	1999-04-11	Improved structure for inserting-hook of curtain
TW428810U (en)	2001-04-01	Improved structure of plug
TW433622U (en)	2001-05-01	Improved structure of plug
GB9820641D0 (en)	1998-11-18	Stabilisation of peroxidases
GB9818178D0 (en)	1998-10-14	Curtain walls
TW380759U (en)	2000-01-21	Structure of extended plug
TW392981U (en)	2000-06-01	Improvement of connector
GB9826768D0 (en)	1999-01-27	Improvements relating to stabilising devices

Legal Events

Date	Code	Title
2006-02-21	EXTN	Extension order renewed
2006-08-01	FF	Patent granted
2013-11-28	KB	Patent renewed
2017-12-31	KB	Patent renewed
2020-07-30	EXP	Patent expired