IL142929A0 - Local delivery of drugs to the colon for local treatment of colonic diseases - Google Patents
Local delivery of drugs to the colon for local treatment of colonic diseasesInfo
- Publication number
- IL142929A0 IL142929A0 IL14292999A IL14292999A IL142929A0 IL 142929 A0 IL142929 A0 IL 142929A0 IL 14292999 A IL14292999 A IL 14292999A IL 14292999 A IL14292999 A IL 14292999A IL 142929 A0 IL142929 A0 IL 142929A0
- Authority
- IL
- Israel
- Prior art keywords
- local
- colon
- drugs
- colonic diseases
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/190,127 US6231888B1 (en) | 1996-01-18 | 1998-11-12 | Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps |
| PCT/IL1999/000607 WO2000028974A1 (en) | 1998-11-12 | 1999-11-12 | Local delivery of drugs to the colon for local treatment of colonic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL142929A0 true IL142929A0 (en) | 2002-04-21 |
Family
ID=22700115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14292999A IL142929A0 (en) | 1998-11-12 | 1999-11-12 | Local delivery of drugs to the colon for local treatment of colonic diseases |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6231888B1 (en) |
| EP (1) | EP1131058A1 (en) |
| AU (1) | AU1175000A (en) |
| IL (1) | IL142929A0 (en) |
| WO (1) | WO2000028974A1 (en) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022683B1 (en) * | 1998-05-13 | 2006-04-04 | Carrington Laboratories, Inc. | Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation |
| US6531152B1 (en) * | 1998-09-30 | 2003-03-11 | Dexcel Pharma Technologies Ltd. | Immediate release gastrointestinal drug delivery system |
| US8236352B2 (en) * | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
| US8293277B2 (en) * | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| US20040013613A1 (en) * | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
| AU6283299A (en) * | 1998-10-01 | 2000-04-17 | Elan Pharma International Limited | Controlled release nanoparticulate compositions |
| BR9916871A (en) * | 1998-11-27 | 2001-08-21 | Kanji Takada | Oral formulation for gastrointestinal drug delivery |
| US20040115134A1 (en) * | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
| US6432979B1 (en) * | 1999-08-12 | 2002-08-13 | American Cyanamid Company | Method of treating or inhibiting colonic polyps and colorectal cancer |
| SE0000774D0 (en) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
| SE0000773D0 (en) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
| WO2001078721A1 (en) * | 2000-04-13 | 2001-10-25 | Mayo Foundation For Medical Education And Research | Aβ42 LOWERING AGENTS |
| WO2001078626A1 (en) * | 2000-04-13 | 2001-10-25 | Sts Biopolymers, Inc. | Targeted therapeutic agent release devices and methods of making and using the same |
| US6761901B1 (en) | 2000-05-02 | 2004-07-13 | Enzrel Inc. | Liposome drug delivery |
| US20040156872A1 (en) * | 2000-05-18 | 2004-08-12 | Elan Pharma International Ltd. | Novel nimesulide compositions |
| CN1285333C (en) * | 2000-06-07 | 2006-11-22 | 张昊 | Colon-releasing oral preparation and its preparing method |
| US6689760B1 (en) | 2000-07-10 | 2004-02-10 | Enzrel Inc. | Anti-mycobacterial compositions |
| US6455073B1 (en) | 2000-07-10 | 2002-09-24 | Enzrel, Inc. | Covalent microparticle-drug conjugates for biological targeting |
| US20040152672A1 (en) * | 2000-08-09 | 2004-08-05 | Carson Dennis A. | Indole compounds useful for the treatment of cancer |
| RU2178300C1 (en) * | 2000-08-17 | 2002-01-20 | Омская государственная медицинская академия | Method to treat polyposis of large intestine |
| US7198795B2 (en) | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
| CA2359812C (en) | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
| US6932861B2 (en) | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| US6777000B2 (en) * | 2001-02-28 | 2004-08-17 | Carrington Laboratories, Inc. | In-situ gel formation of pectin |
| US7494669B2 (en) * | 2001-02-28 | 2009-02-24 | Carrington Laboratories, Inc. | Delivery of physiological agents with in-situ gels comprising anionic polysaccharides |
| US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
| DE60237087D1 (en) * | 2001-06-01 | 2010-09-02 | Pozen Inc | PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAID |
| SE0102993D0 (en) | 2001-09-07 | 2001-09-07 | Astrazeneca Ab | New self emulsifying drug delivery system |
| US7550156B2 (en) * | 2001-11-23 | 2009-06-23 | Rohm And Haas Company | Optimised pellet formulations |
| EP1314776B1 (en) * | 2001-11-23 | 2007-05-23 | Rohm And Haas Company | Optimised pellet formulations |
| WO2003053402A1 (en) * | 2001-12-20 | 2003-07-03 | Pharmacia Corporation | Zero-order sustained released dosage forms and method of making the same |
| WO2003059288A2 (en) * | 2002-01-09 | 2003-07-24 | Enzrel, Inc. | Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds |
| US20040101566A1 (en) * | 2002-02-04 | 2004-05-27 | Elan Pharma International Limited | Novel benzoyl peroxide compositions |
| EP1428528A1 (en) * | 2002-09-27 | 2004-06-16 | Tiense Suikerraffinaderij N.V. | Synergistic combinations of dietary fiber and NSAIDs for the treatment of cancer |
| CA2501324A1 (en) * | 2002-10-30 | 2004-05-21 | Pharmacia Corporation | Oral extended release tablets and methods of making and using the same |
| EP1603548A4 (en) * | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS |
| ES2213485B1 (en) * | 2003-02-13 | 2005-12-16 | Almirall Prodesfarma, S.A. | DERIVATIVES OF 2-FENILPIRAN-4-ONA. |
| ES2214130B1 (en) * | 2003-02-13 | 2005-12-01 | Almirall Prodesfarma, S.A. | 2-3'-BIPIRIDINES. |
| ES2214129B1 (en) * | 2003-02-13 | 2005-12-01 | Almirall Prodesfarma, S.A. | 3-FENILFURAN-2-ONAS. |
| CA2523339A1 (en) * | 2003-04-25 | 2004-11-11 | Kouki Bussan Yugenkaisha | Agent for preventing and healing constipation |
| US20040248858A1 (en) * | 2003-06-09 | 2004-12-09 | Parghi Kaumil H. | Cure for cancer |
| WO2005065069A2 (en) * | 2003-07-11 | 2005-07-21 | Myriad Genetics, Inc. | Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease |
| CA2534241C (en) * | 2003-07-31 | 2012-05-29 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treating, preventing and/or ameliorating cancers, the onset of cancers or the symptoms of cancers |
| SI21638A (en) * | 2003-11-12 | 2005-06-30 | LEK farmacevtska dru�ba d.d. | A pharmaceutical formulation with controlled release of ketoprofen |
| NZ549661A (en) | 2004-02-06 | 2010-07-30 | Pharmatel R & D Pty Ltd As Tru | Use of aminosalicylates in diarrhoea-predominant irritable bowel syndrome |
| WO2005086909A2 (en) * | 2004-03-08 | 2005-09-22 | Mayo Foundation For Medical Education And Research | Protein kinase c iota |
| WO2006001877A2 (en) * | 2004-04-13 | 2006-01-05 | Myriad Genetics, Inc. | Combination treatment for neurodegenerative disorders comprising r-flurbiprofen |
| KR20070004036A (en) * | 2004-04-29 | 2007-01-05 | 키스톤 리테이닝 월 시스템스, 아이엔씨 | Veneers for Walls, Retaining Walls and Others |
| CA2467894A1 (en) * | 2004-05-20 | 2005-11-20 | Medical Futures Inc. | A composition for prevention and treatment of colon adenomas |
| US20080306029A1 (en) * | 2004-05-28 | 2008-12-11 | Salix Pharmaceuticals, Inc. | Prevention, Treatment, and Amelioration of Radiation Induced Enteritis |
| US8377906B2 (en) * | 2004-06-04 | 2013-02-19 | Ethicon, Inc. | Compositions and methods for preventing or reducing postoperative ileus and gastric stasis |
| US8129359B2 (en) | 2004-06-04 | 2012-03-06 | Ethicon, Inc. | Composition and method for treating post-surgical pain |
| BRPI0514303A (en) * | 2004-08-11 | 2008-06-10 | Myriad Genetics Inc | pharmaceutical composition and method for treating neurodegenerative disorders |
| WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| WO2006102439A2 (en) * | 2005-03-23 | 2006-09-28 | Florida Atlantic University | Treatment or prevention of cancer and precancerous disorders |
| US20060280795A1 (en) * | 2005-06-08 | 2006-12-14 | Dexcel Pharma Technologies, Ltd. | Specific time-delayed burst profile delivery system |
| BRPI0613611A2 (en) * | 2005-07-22 | 2011-01-18 | Myriad Genetics Inc | high concentration drug formulations and dosage forms |
| US8921344B2 (en) * | 2006-11-03 | 2014-12-30 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| US7452872B2 (en) | 2005-08-24 | 2008-11-18 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| JP2009506067A (en) * | 2005-08-24 | 2009-02-12 | サリックス ファーマシューティカルズ， インコーポレイテッド | Formulation of balsalazide and its manufacture and use |
| EP2035008B1 (en) | 2006-06-13 | 2011-11-23 | Ethicon, Incorporated | Compositions and methods for preventing or reducing postoperative ileus and gastric stasis in mammals |
| EP2046119A2 (en) * | 2006-07-07 | 2009-04-15 | Myriad Genetics, Inc. | Treatment of psychiatric disorders |
| US20100055173A1 (en) * | 2006-10-10 | 2010-03-04 | Adel Penhasi | Release of statins in the intestine |
| US20090036414A1 (en) * | 2007-08-02 | 2009-02-05 | Mutual Pharmaceutical Company, Inc. | Mesalamine Formulations |
| US20090043317A1 (en) * | 2007-08-08 | 2009-02-12 | Cavanaugh Brian J | Method and apparatus for delivery of a ligating suture |
| BRPI0918492A2 (en) | 2008-09-09 | 2015-12-01 | Astrazeneca Ab | use of naproxen, or pharmaceutically acceptable salt thereof, and esomeprazole, or pharmaceutically acceptable salt thereof |
| ES2425762T3 (en) | 2008-10-27 | 2013-10-17 | Roquette Freres | Water insoluble polymer: film coatings based on modified starch derivatives for colon-directed release |
| WO2010056741A2 (en) * | 2008-11-12 | 2010-05-20 | Auspex Pharmaceuticals, Inc. | Phenylacetic acid inhibitors of cyclooxygenase |
| EP2445499A4 (en) | 2009-06-25 | 2013-02-27 | Astrazeneca Ab | METHOD FOR THE TREATMENT OF A PATIENT AT RISK OF DEVELOPING A ULCERE ASSOCIATED WITH NSAID |
| EA021112B1 (en) * | 2009-06-25 | 2015-04-30 | Поузен Инк. | Method for treating pain and/or inflammation in a patient in need of aspirin therapy |
| US20130115280A1 (en) | 2010-07-29 | 2013-05-09 | Cosmo Technologies Ltd | Pharmaceutical and/or dietary compositions based on sort chain fatty acids |
| US9433583B2 (en) | 2011-04-22 | 2016-09-06 | Frank J. Farrell | Colon vitamin |
| CA2860231A1 (en) | 2011-12-28 | 2013-07-04 | Pozen Inc. | Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid |
| MA40687A (en) * | 2014-04-10 | 2017-03-28 | Ifom Fondazione St Firc Di Oncologia Molecolare | VASCULAR MALFORMATION TREATMENT METHODS AND COMPOSITIONS |
| US10182993B2 (en) | 2015-04-06 | 2019-01-22 | Patheon Softgels Inc. | Compositions for colonic delivery of drugs |
| US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| WO2018090266A1 (en) * | 2016-11-17 | 2018-05-24 | 上海交通大学医学院 | Oral colon-targeted delivery system and preparation method and application thereof |
| JP2020512624A (en) * | 2017-03-07 | 2020-04-23 | アニヴァイヴ ライフサイエンシーズ インコーポレイテッド | Drug discovery platform |
| US20220072013A1 (en) | 2018-12-21 | 2022-03-10 | Ca*Tx, Inc. | Pharmaceutical Combinations for the Treatment of Cancer |
| KR20220046623A (en) | 2019-08-12 | 2022-04-14 | 메사추세츠 인스티튜트 오브 테크놀로지 | Articles and methods for administration of therapeutic agents |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3921636A (en) | 1973-01-15 | 1975-11-25 | Alza Corp | Novel drug delivery device |
| US4107288A (en) | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| JPS5186117A (en) | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
| GB1538075A (en) | 1975-03-24 | 1979-01-10 | Champion Paper Co Ltd | Formation of microcapsules by interfacial cross-linking and microcapsules produced thereby |
| US4277364A (en) | 1975-12-22 | 1981-07-07 | The United States Of America As Represented By The Secretary Of Agriculture | Encapsulation by entrapment |
| US4344857A (en) | 1975-12-22 | 1982-08-17 | The United States Of America As Represented By The Secretary Of Agriculture | Encapsulation by entrapment |
| US4169804A (en) | 1976-08-19 | 1979-10-02 | Minnesota Mining And Manufacturing Company | Magnetically responsive composite microparticle |
| DE2712161C2 (en) | 1977-03-19 | 1983-01-05 | Blendax-Werke R. Schneider Gmbh & Co, 6500 Mainz | Dental and oral care products |
| US4307717A (en) | 1977-11-07 | 1981-12-29 | Lectec Corporation | Sterile improved bandage containing a medicament |
| US4279812A (en) | 1979-09-12 | 1981-07-21 | Seton Company | Process for preparing macromolecular biologically active collagen |
| JPS5911563B2 (en) | 1980-02-27 | 1984-03-16 | 日本原子力研究所 | Method for manufacturing multilayer sustained release composites |
| US4348384A (en) | 1980-10-17 | 1982-09-07 | Dainippon Pharmaceutical Co., Ltd. | Pharmaceutical composition for oral administration containing coagulation factor VIII or IX |
| US4349530A (en) | 1980-12-11 | 1982-09-14 | The Ohio State University | Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal |
| US4442655A (en) | 1981-06-25 | 1984-04-17 | Serapharm Michael Stroetmann | Fibrinogen-containing dry preparation, manufacture and use thereof |
| JPS59222406A (en) | 1983-06-01 | 1984-12-14 | Teijin Ltd | Pharmaceutical preparation for remedying periodontosis and its preparation |
| CA1196863A (en) | 1983-06-08 | 1985-11-19 | Mattheus F.A. Goosen | Slow release injectable insulin composition |
| DE3463211D1 (en) | 1983-07-01 | 1987-05-21 | Battelle Memorial Institute | Biodegradable polypeptide and its use in the sustained release of medicaments |
| MX163953B (en) | 1984-03-27 | 1992-07-03 | Univ New Jersey Med | PROCEDURE FOR PREPARING A BIODEGRADABLE COLLAGEN MATRIX |
| US4619913A (en) | 1984-05-29 | 1986-10-28 | Matrix Pharmaceuticals, Inc. | Treatments employing drug-containing matrices for introduction into cellular lesion areas |
| US4678516A (en) | 1984-10-09 | 1987-07-07 | The Dow Chemical Company | Sustained release dosage form based on highly plasticized cellulose ether gels |
| US4568536A (en) | 1985-02-08 | 1986-02-04 | Ethicon, Inc. | Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition |
| US4794002A (en) | 1985-11-01 | 1988-12-27 | Monsanto Company | Modified polymeric surfaces and process for preparing same |
| US4803075A (en) | 1986-06-25 | 1989-02-07 | Collagen Corporation | Injectable implant composition having improved intrudability |
| GB8926639D0 (en) | 1989-11-24 | 1990-01-17 | Agricultural & Food Res | Delayed release formulations |
| IL98087A (en) | 1990-05-04 | 1996-11-14 | Perio Prod Ltd | Colonic drug delivery system |
| SE9002339L (en) | 1990-07-04 | 1992-01-05 | Kabi Pharmacia Ab | THERAPEUTIC COMPOSITION AND PROCEDURE FOR ITS PREPARATION |
| AU659106B2 (en) | 1990-11-06 | 1995-05-11 | Fgn, Inc. | Method for treating colonic polyps by the use of esters and amides of substituted phenyl and pyridyl amino carboxylates |
| AU650914B2 (en) | 1990-11-06 | 1994-07-07 | Fgn, Inc. | Esters and amides of substituted phenyl acetic acids |
| AU659107B2 (en) | 1990-11-06 | 1995-05-11 | Fgn, Inc. | Method for treating colonic polyps by the use of esters and amides of substituted fused ring phenyl acetic acids |
| AU658373B2 (en) | 1990-11-06 | 1995-04-13 | Fgn, Inc. | Esters and amides of substituted pyrrole acetic acids |
| AU650689B2 (en) | 1990-11-06 | 1994-06-30 | Fgn, Inc. | Esters and amides of substituted indenyl acetic acids |
| US5422121A (en) | 1990-11-14 | 1995-06-06 | Rohm Gmbh | Oral dosage unit form |
| AU650720B2 (en) | 1991-03-08 | 1994-06-30 | Fgn, Inc. | Method for treating patients with precancerous lesions by administering substituted sulfonyl indenyl acetic and propionic acids and esters thereof |
| US5401774A (en) | 1991-03-08 | 1995-03-28 | University Of Arizona | Method for treating patients with precancerous lesions by administering substituted sulfonyl idenyl acetic and propionic acids and esters to patients with lesions sensitive to such compounds |
| AU2140492A (en) | 1991-05-14 | 1992-12-30 | Biopure Corporation | Use of hemoglobin in a method for the treatment of tumors with chemotherapeutic agents |
| DE4236025A1 (en) | 1992-10-24 | 1994-04-28 | Merck Patent Gmbh | Oral dosage forms |
| US5656290A (en) | 1993-02-26 | 1997-08-12 | The Procter & Gamble Company | Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery |
| US5686105A (en) | 1993-10-19 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
| US5651983A (en) | 1993-02-26 | 1997-07-29 | The Procter & Gamble Company | Bisacodyl dosage form for colonic delivery |
| JP3725542B2 (en) | 1993-10-19 | 2005-12-14 | 大正製薬株式会社 | Picosulfate dosage form |
| US5514663A (en) | 1993-10-19 | 1996-05-07 | The Procter & Gamble Company | Senna dosage form |
| US5498608A (en) | 1994-01-07 | 1996-03-12 | Salix Pharmaceuticals | Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents |
| US5464633A (en) | 1994-05-24 | 1995-11-07 | Jagotec Ag | Pharmaceutical tablets releasing the active substance after a definite period of time |
| US5622948A (en) | 1994-12-01 | 1997-04-22 | Syntex (U.S.A.) Inc. | Pyrrole pyridazine and pyridazinone anti-inflammatory agents |
| US5686106A (en) | 1995-05-17 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form for colonic delivery |
| DE19680594D2 (en) | 1995-07-20 | 1997-09-18 | Uwe Juergens | Use of a non-steroidal anti-inflammatory drug for topical and systemic treatment of acute and chronic polypoid rhinosinusitis |
| US5840332A (en) | 1996-01-18 | 1998-11-24 | Perio Products Ltd. | Gastrointestinal drug delivery system |
| US5795909A (en) | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| ES2198756T3 (en) * | 1997-10-09 | 2004-02-01 | Dexcel Pharma Technologies Ltd. | ADMINISTRATION SYSTEM OF TOTAL RELEASE PHARMACOS DELAYED IN THE GASTROINTESTINAL TRACT. |
-
1998
- 1998-11-12 US US09/190,127 patent/US6231888B1/en not_active Expired - Fee Related
-
1999
- 1999-11-12 AU AU11750/00A patent/AU1175000A/en not_active Abandoned
- 1999-11-12 IL IL14292999A patent/IL142929A0/en active IP Right Grant
- 1999-11-12 EP EP99972097A patent/EP1131058A1/en not_active Withdrawn
- 1999-11-12 WO PCT/IL1999/000607 patent/WO2000028974A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US6231888B1 (en) | 2001-05-15 |
| WO2000028974A1 (en) | 2000-05-25 |
| AU1175000A (en) | 2000-06-05 |
| EP1131058A1 (en) | 2001-09-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL142929A0 (en) | Local delivery of drugs to the colon for local treatment of colonic diseases | |
| PL354540A1 (en) | Drugs for the treatment of malignant tumours | |
| IL149224A0 (en) | Hydrogen-driven drug dosage form | |
| IL196301A0 (en) | Medicament for the treatment of hapatitis c | |
| HUP0004286A3 (en) | Use of quinazoline derivatives for producing pharmaceutical compositions for treating colonic polyps | |
| PL342515A1 (en) | Drug administering device | |
| HUP0103856A3 (en) | Pharmaceutical composition for the treatment of acute disorders | |
| IL147217A0 (en) | New spirooxindole derivatives and pharmaceutical compositions containing the same for treatment of pain | |
| AU2001276860A1 (en) | Medicaments for chemotherapeutic treatment of disease | |
| HUP0104963A3 (en) | Compositions for the treatment of skin diseases | |
| HUP0001084A3 (en) | Modified release oral pharmaceutical composition containing 5-asa for the treatment of bowel diseases | |
| AU7728698A (en) | Oral formulations for treatment of bacteria-induced diseases of the colon | |
| IL147946A0 (en) | Treatment of inflammatory or malignant disease using dnazymes | |
| AU1751997A (en) | Targeted delivery of drugs to the lower gastrointestinal tract | |
| HUP0201667A3 (en) | Oral form of administration | |
| GB2333042B (en) | Colonic delivery of weak acid drugs | |
| IL121647A0 (en) | Pharmaceutical compositions for the treatment of ocular inflammations comprising dexamethasone palmitate | |
| EP1114642A4 (en) | Drugs for periodontal diseases | |
| ZA984650B (en) | Intratumoral administration of triphenylethylenes for the treatment of cancer | |
| AU6274101A (en) | Medicines for the prevention and treatment of neurodegenerative diseases | |
| IL141339A0 (en) | Liquid pharmaceutical for oral delivery | |
| PL325509A1 (en) | Therapeutic agent for oral administration | |
| HUP0000569A3 (en) | Use of equilenin for producing pharmaceutical compositions for the treatment of free radical induced disease states | |
| GC0000176A (en) | Pharmaceutical combination preparations for the treatment of cardiac disorders | |
| HUP0104491A3 (en) | Use of amtolmetin guacyl for the production of anti-inflammatory drugs for intestinal inflammations |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| FF | Patent granted | ||
| KB | Patent renewed |