IL149402A0 - Arylamine derivatives and their use as anti-telomerase agent - Google Patents

Arylamine derivatives and their use as anti-telomerase agent

Info

Publication number: IL149402A0
Authority: IL; Israel
Prior art keywords: arylamine derivatives; telomerase agent; telomerase; agent; concerns
Prior art date: 1999-11-29

Application number

IL14940200A

Other languages

English (en)

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-29

Filing date

2000-11-27

Publication date

2002-11-10

1999-11-29 Priority claimed from FR9915031A external-priority patent/FR2801588B1/fr

2000-11-27 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2002-11-10 Publication of IL149402A0 publication Critical patent/IL149402A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Quinoline Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL14940200A 1999-11-29 2000-11-27 Arylamine derivatives and their use as anti-telomerase agent IL149402A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9915031A FR2801588B1 (fr)	1999-11-29	1999-11-29	Derives chimiques et leur application comme agent antitelomerase
FR0010561		2000-08-11
PCT/FR2000/003310 WO2001040218A1 (fr)	1999-11-29	2000-11-27	Derives arylamines et leur application comme agent antitelomerase

Publications (1)

Publication Number	Publication Date
IL149402A0 true IL149402A0 (en)	2002-11-10

Family

ID=26212577

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14940200A IL149402A0 (en)	1999-11-29	2000-11-27	Arylamine derivatives and their use as anti-telomerase agent

Country Status (27)

Country	Link
EP (1)	EP1244650B1 (xx)
JP (1)	JP2003515604A (xx)
KR (1)	KR20020058043A (xx)
CN (1)	CN1402722A (xx)
AT (1)	ATE243692T1 (xx)
AU (1)	AU2179001A (xx)
BG (1)	BG106753A (xx)
BR (1)	BR0015992A (xx)
CA (1)	CA2392507A1 (xx)
CO (1)	CO5251431A1 (xx)
CZ (1)	CZ20021849A3 (xx)
DE (1)	DE60003583T2 (xx)
DK (1)	DK1244650T3 (xx)
EA (1)	EA200200616A1 (xx)
EE (1)	EE200200263A (xx)
ES (1)	ES2202206T3 (xx)
HU (1)	HUP0204429A2 (xx)
IL (1)	IL149402A0 (xx)
MX (1)	MXPA02005276A (xx)
NO (1)	NO20022528L (xx)
PE (1)	PE20010912A1 (xx)
PL (1)	PL355667A1 (xx)
PT (1)	PT1244650E (xx)
SK (1)	SK7402002A3 (xx)
UY (1)	UY26456A1 (xx)
WO (1)	WO2001040218A1 (xx)
YU (1)	YU38102A (xx)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2386218A1 (en)	1999-10-07	2001-04-12	Amgen Inc.	Triazine kinase inhibitors
AU2001228638A1 (en)	2000-01-28	2001-08-07	Astrazeneca Ab	Chemical compounds
AU2001237041B9 (en)	2000-02-17	2005-07-28	Amgen Inc.	Kinase inhibitors
AU2001282268A1 (en) *	2000-08-08	2002-02-18	Aventis Pharma S.A.	Phenantridine derivatives and their use as anti-telomerase agent
CA2432000C (en)	2000-12-21	2011-03-15	Glaxo Group Limited	Pyrimidineamines as angiogenesis modulators
FR2821355A1 (fr) *	2001-02-23	2002-08-30	Aventis Pharma Sa	Derives chimiques et leur application comme agent antitelomerase
FR2822468B1 (fr) *	2001-03-23	2008-06-20	Aventis Pharma Sa	Derives chimiques et leur application comme agent anti-telomerase
US6887873B2 (en)	2001-03-23	2005-05-03	Aventis Pharma S.A.	Triazine derivatives and their application as antitelomerase agents
CO5380035A1 (es) *	2001-03-23	2004-03-31	Aventis Pharma Sa	Derivados quimicos y su aplicacion como agente antitelomerasa
AU2002314252A1 (en) *	2001-05-28	2002-12-09	Aventis Pharma S.A.	Chemical derivatives and the use thereof as an anti-telomerase agent
US7115617B2 (en) *	2001-08-22	2006-10-03	Amgen Inc.	Amino-substituted pyrimidinyl derivatives and methods of use
US6939874B2 (en) *	2001-08-22	2005-09-06	Amgen Inc.	Substituted pyrimidinyl derivatives and methods of use
US7132423B2 (en)	2001-09-21	2006-11-07	Reddy Us Therapeutics, Inc.	Methods and compositions of novel triazine compounds
US7112587B2 (en)	2001-09-21	2006-09-26	Reddy Us Therapeutics, Inc.	Methods and compositions of novel triazine compounds
US7173032B2 (en)	2001-09-21	2007-02-06	Reddy Us Therapeutics, Inc.	Methods and compositions of novel triazine compounds
US7163943B2 (en)	2001-09-21	2007-01-16	Reddy Us Therapeutics, Inc.	Methods and compositions of novel triazine compounds
US7169785B2 (en)	2001-09-21	2007-01-30	Reddy Us Therapeutics, Inc.	Methods and compositions of novel triazine compounds
US7084156B2 (en)	2001-11-27	2006-08-01	Merck & Co., Inc.	2-Aminoquinoline compounds
MXPA05001883A (es) *	2002-09-10	2005-06-03	Pharmacia Italia Spa	Derivados de piridina sustituidos como agentes antitumorales.
AU2003275726A1 (en) *	2002-10-24	2004-05-13	Chong Kun Dang Pharmaceutical Corp.	2 - substituted heterocyclic compounds and antitumor composition comprising the same
FR2850970B1 (fr) *	2003-02-07	2006-07-07	Aventis Pharma Sa	Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique
US7517890B2 (en) *	2003-11-20	2009-04-14	Children's Hospital Medical Center	GTPase inhibitors and methods of use
US7335770B2 (en)	2004-03-24	2008-02-26	Reddy U5 Therapeutics, Inc.	Triazine compounds and their analogs, compositions, and methods
EP1940965B1 (en) *	2005-10-28	2014-03-26	Almac Sciences (Scotland) Limited	Novel fluorescent dyes and uses thereof
US7713987B2 (en)	2005-12-06	2010-05-11	Rigel Pharmaceuticals, Inc.	Pyrimidine-2,4-diamines and their uses
KR100761869B1 (ko) *	2006-07-07	2007-10-04	김현기	트리아진 유도체 화합물 및 이를 포함하는 암 치료용조성물
EP2441757A1 (en) *	2006-07-31	2012-04-18	Praecis Pharmaceuticals Incorporated	Aurora kinase inhibitors from an encoded small molecule library
JP5325517B2 (ja) *	2007-10-12	2013-10-23	住友化学株式会社	ジベンゾオキセピン化合物の精製方法
JP2009102249A (ja) *	2007-10-22	2009-05-14	Sumitomo Chemical Co Ltd	ジベンゾオキセピン化合物の結晶の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9206768D0 (en) *	1992-03-27	1992-05-13	Jarman Michael	New compounds for use in the treatment of cancer
US5770613A (en) *	1995-09-29	1998-06-23	Geron Corporation	Telomerase inhibitors
JPH1160573A (ja) *	1997-08-22	1999-03-02	Nippon Kayaku Co Ltd	トリアジン誘導体及びテロメラーゼ阻害剤
WO1999040087A2 (en) *	1998-02-04	1999-08-12	The Board Of Regents, The University Of Texas System	Inhibition of human telomerase by a g-quadruplex-interaction compound
DE19812879A1 (de) *	1998-03-24	1999-09-30	Bayer Ag	Substituierte 2,4-Diamino-1,3,5-triazine

2000
- 2000-11-27 KR KR1020027006786A patent/KR20020058043A/ko not_active Withdrawn
- 2000-11-27 DK DK00985339T patent/DK1244650T3/da active
- 2000-11-27 AT AT00985339T patent/ATE243692T1/de not_active IP Right Cessation
- 2000-11-27 JP JP2001541902A patent/JP2003515604A/ja not_active Withdrawn
- 2000-11-27 SK SK740-2002A patent/SK7402002A3/sk unknown
- 2000-11-27 CZ CZ20021849A patent/CZ20021849A3/cs unknown
- 2000-11-27 YU YU38102A patent/YU38102A/sh unknown
- 2000-11-27 DE DE60003583T patent/DE60003583T2/de not_active Expired - Fee Related
- 2000-11-27 EP EP00985339A patent/EP1244650B1/fr not_active Expired - Lifetime
- 2000-11-27 CN CN00816440A patent/CN1402722A/zh active Pending
- 2000-11-27 EA EA200200616A patent/EA200200616A1/ru unknown
- 2000-11-27 PT PT00985339T patent/PT1244650E/pt unknown
- 2000-11-27 MX MXPA02005276A patent/MXPA02005276A/es unknown
- 2000-11-27 BR BR0015992-1A patent/BR0015992A/pt not_active IP Right Cessation
- 2000-11-27 CA CA002392507A patent/CA2392507A1/fr not_active Abandoned
- 2000-11-27 PL PL00355667A patent/PL355667A1/xx not_active Application Discontinuation
- 2000-11-27 IL IL14940200A patent/IL149402A0/xx unknown
- 2000-11-27 HU HU0204429A patent/HUP0204429A2/hu unknown
- 2000-11-27 EE EEP200200263A patent/EE200200263A/xx unknown
- 2000-11-27 WO PCT/FR2000/003310 patent/WO2001040218A1/fr not_active Ceased
- 2000-11-27 ES ES00985339T patent/ES2202206T3/es not_active Expired - Lifetime
- 2000-11-27 AU AU21790/01A patent/AU2179001A/en not_active Abandoned
- 2000-11-28 PE PE2000001265A patent/PE20010912A1/es not_active Application Discontinuation
- 2000-11-28 UY UY26456A patent/UY26456A1/es not_active Application Discontinuation
- 2000-11-28 CO CO00090981A patent/CO5251431A1/es not_active Application Discontinuation
2002
- 2002-05-28 NO NO20022528A patent/NO20022528L/no not_active Application Discontinuation
- 2002-05-29 BG BG106753A patent/BG106753A/bg unknown

Also Published As

Publication number	Publication date
EP1244650B1 (fr)	2003-06-25
EP1244650A1 (fr)	2002-10-02
YU38102A (sh)	2004-12-31
DE60003583T2 (de)	2004-05-13
KR20020058043A (ko)	2002-07-12
BR0015992A (pt)	2002-08-06
EE200200263A (et)	2003-06-16
HUP0204429A2 (hu)	2003-04-28
PE20010912A1 (es)	2001-09-01
NO20022528D0 (no)	2002-05-28
ATE243692T1 (de)	2003-07-15
WO2001040218A1 (fr)	2001-06-07
BG106753A (bg)	2003-02-28
EA200200616A1 (ru)	2002-10-31
CA2392507A1 (fr)	2001-06-07
AU2179001A (en)	2001-06-12
CO5251431A1 (es)	2003-02-28
CZ20021849A3 (cs)	2002-08-14
UY26456A1 (es)	2001-06-29
JP2003515604A (ja)	2003-05-07
NO20022528L (no)	2002-05-28
PT1244650E (pt)	2003-11-28
ES2202206T3 (es)	2004-04-01
CN1402722A (zh)	2003-03-12
DE60003583D1 (de)	2003-07-31
PL355667A1 (en)	2004-05-04
DK1244650T3 (da)	2003-10-20
MXPA02005276A (es)	2002-11-07
SK7402002A3 (en)	2002-11-06

Publication	Publication Date	Title
IL149402A0 (en)	2002-11-10	Arylamine derivatives and their use as anti-telomerase agent
DE60112974D1 (en)	2005-09-29	Carbolinderivate
BG108269A (en)	2004-12-30	Pyrazolopyrimidines as therapeutic agents
WO2002096903A3 (fr)	2003-04-17	Derives chimiques et leur application comme agent antitelomerase
BG108268A (en)	2005-04-30	Pyrazolopyrimidines as therapeutic agents
DE60216233D1 (en)	2007-01-04	Carbolinderivate
MXPA06000247A (es)	2006-03-30	Tetrahidro-1h-pirazolo[3,4-c]piridinas sustituidas composiciones que las contienen y su utilizacion.
GB9514473D0 (en)	1995-09-13	Chemical compounds
BG106586A (en)	2003-01-31	Pyrazolopyramidines as therapeutic agents
AU6048201A (en)	2001-12-17	Quinazoline derivatives for the treatment of tumours
MXPA02012076A (es)	2003-06-06	Compuestos quimicos.
ATE231872T1 (de)	2003-02-15	Thiazolopyrimidinderivate
MXPA02012659A (es)	2003-09-22	Derivados de pirazindiona condensados.
HUP0500424A2 (en)	2007-02-28	Combination therapy for the treatment of cancer
WO2002070469A3 (en)	2004-03-04	Selective pde3b inhibitors and use of the same in therapy
SE9904377D0 (sv)	1999-12-01	Pharmaceutical combinations
MY130957A (en)	2007-07-31	Triazine derivatives and their application as antitelomerase agents
MXPA03002909A (es)	2003-09-10	Compuestos quimicos.
GB0018951D0 (en)	2000-09-20	Novel compounds
IL165086A0 (en)	2005-12-18	Cyanoguanidine prodrugs
MXPA02012472A (es)	2004-01-26	Compuestos quimicos.
MXPA03003971A (es)	2004-02-12	Derivados de indol como inhibidores de pde5.
GB0027705D0 (en)	2000-12-27	Novel compounds
MXPA04005226A (es)	2004-10-11	1,3-diarilprop-2-en-1-onas, composiciones que las contienen y su utilizacion.
HRP20020262A2 (en)	2004-04-30	Substituted pyrroles as antiproliferative agents for the treatment of cancer