IL146162A0 - Macrolide compounds for the treatment of dry eye - Google Patents
Macrolide compounds for the treatment of dry eyeInfo
- Publication number
- IL146162A0 IL146162A0 IL14616200A IL14616200A IL146162A0 IL 146162 A0 IL146162 A0 IL 146162A0 IL 14616200 A IL14616200 A IL 14616200A IL 14616200 A IL14616200 A IL 14616200A IL 146162 A0 IL146162 A0 IL 146162A0
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- dry eye
- macrolide compounds
- macrolide
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13200999P | 1999-04-30 | 1999-04-30 | |
| PCT/JP2000/002756 WO2000066122A1 (en) | 1999-04-30 | 2000-04-26 | Use of macrolide compounds for the treatment of dry eye |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL146162A0 true IL146162A0 (en) | 2002-07-25 |
Family
ID=22452015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14616200A IL146162A0 (en) | 1999-04-30 | 2000-04-26 | Macrolide compounds for the treatment of dry eye |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1173177B2 (es) |
| JP (2) | JP5036934B2 (es) |
| KR (1) | KR20020015316A (es) |
| CN (1) | CN1190194C (es) |
| AR (1) | AR023807A1 (es) |
| AT (1) | ATE281167T1 (es) |
| AU (1) | AU777915B2 (es) |
| BR (1) | BR0011225A (es) |
| CA (1) | CA2372448A1 (es) |
| CZ (1) | CZ20013769A3 (es) |
| DE (1) | DE60015516T2 (es) |
| ES (1) | ES2232439T3 (es) |
| HK (2) | HK1043321B (es) |
| HU (1) | HUP0200864A3 (es) |
| IL (1) | IL146162A0 (es) |
| MX (1) | MXPA01010988A (es) |
| NO (1) | NO20015288D0 (es) |
| NZ (1) | NZ515339A (es) |
| PT (1) | PT1173177E (es) |
| TR (1) | TR200103119T2 (es) |
| TW (1) | TWI230066B (es) |
| WO (1) | WO2000066122A1 (es) |
| ZA (1) | ZA200108905B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ20013769A3 (cs) * | 1999-04-30 | 2002-03-13 | Sucampo Ag | Činidlo pro léčbu suchého oka |
| US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
| EP1406700A1 (en) | 2001-07-06 | 2004-04-14 | Sucampo AG | Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent |
| TWI324925B (en) * | 2001-08-23 | 2010-05-21 | Novartis Ag | Ophthalmic composition |
| AR038628A1 (es) * | 2002-03-04 | 2005-01-19 | Novartis Ag | Composicion oftalmica |
| JP2005536531A (ja) * | 2002-08-09 | 2005-12-02 | スキャンポ ファーマシューティカルズ、インコーポレイテッド | アレルギー性疾患を処置する為のfk506誘導体を含む医薬組成物及びその使用 |
| US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| WO2004062669A1 (en) * | 2003-01-16 | 2004-07-29 | Sucampo Ag | Use of a macrolide compound for treating dry eye |
| US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
| US7083802B2 (en) * | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| CA2539324A1 (en) | 2003-09-18 | 2005-03-31 | Macusight, Inc. | Transscleral delivery |
| US7083803B2 (en) | 2003-09-19 | 2006-08-01 | Advanced Ocular Systems Limited | Ocular solutions |
| US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
| WO2005032534A1 (ja) | 2003-10-06 | 2005-04-14 | Ophtecs Corporation | 涙液異常の治療のための眼科用組成物 |
| GB2438544A (en) | 2005-02-09 | 2007-11-28 | Cooper Internat Corp | Liquid formulations for treatment of diseases or conditions |
| EP1904056B1 (en) | 2005-07-18 | 2009-04-29 | Minu, L.L.C. | Use of a macrolide to restore corneal sensation |
| JP5528708B2 (ja) | 2006-02-09 | 2014-06-25 | 参天製薬株式会社 | 安定な製剤ならびにそれらを調製および使用する方法 |
| AU2007230964B2 (en) | 2006-03-23 | 2012-07-19 | Santen Pharmaceutical Co., Ltd. | Formulations and methods for vascular permeability-related diseases or conditions |
| EP2335735A1 (en) * | 2009-12-14 | 2011-06-22 | Novaliq GmbH | Pharmaceutical composition for treatment of dry eye syndrome |
| KR20200069261A (ko) * | 2017-05-30 | 2020-06-16 | 엑시모어 엘티디. | 항생제 마크로라이드를 전달하는 안구건조증을 치료하기 위한 조성물 및 방법 |
| EP3691654A4 (en) | 2017-09-25 | 2021-11-24 | Surface Pharmaceuticals, Inc. | OPHTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF EYE SURFACE DISEASES |
| SG11202106967QA (en) | 2018-12-27 | 2021-07-29 | Surface Ophthalmics Inc | Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease |
| US12440510B2 (en) | 2021-05-10 | 2025-10-14 | Surface Ophthalmics, Inc. | Use of chondroitin sulfate for relieving ocular pain |
| CN117979951A (zh) | 2021-05-10 | 2024-05-03 | 瑟菲斯眼科股份有限公司 | 一种用于缓解眼部疼痛的硫酸软骨素的用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69016515T2 (de) * | 1989-07-05 | 1995-06-08 | Fujisawa Pharmaceutical Co | Wässriges flüssiges Mittel zur äusserlichen Anwendung. |
| US5514686A (en) * | 1991-04-26 | 1996-05-07 | Fujisawa Pharmaceutical Co., Ltd. | Use of macrolide compounds for eye diseases |
| IL102414A (en) * | 1991-07-25 | 1996-08-04 | Univ Louisville Res Found | Medicinal preparations for the treatment of ocular inflammation, containing rapamycin |
| AR004480A1 (es) * | 1995-04-06 | 1998-12-16 | Amico Derin C D | Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen |
| GB9601120D0 (en) * | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
| US6673807B1 (en) * | 1998-04-06 | 2004-01-06 | Fujisawa Pharmaceutical Co., Ltd. | Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins |
| WO1999055332A1 (en) * | 1998-04-27 | 1999-11-04 | Fujisawa Pharmaceutical Co., Ltd. | Medicinal compositions |
| US6376517B1 (en) * | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
| CZ20013769A3 (cs) * | 1999-04-30 | 2002-03-13 | Sucampo Ag | Činidlo pro léčbu suchého oka |
-
2000
- 2000-04-26 CZ CZ20013769A patent/CZ20013769A3/cs unknown
- 2000-04-26 BR BR0011225-9A patent/BR0011225A/pt not_active IP Right Cessation
- 2000-04-26 CN CNB008067686A patent/CN1190194C/zh not_active Expired - Fee Related
- 2000-04-26 WO PCT/JP2000/002756 patent/WO2000066122A1/en not_active Ceased
- 2000-04-26 CA CA002372448A patent/CA2372448A1/en not_active Abandoned
- 2000-04-26 HK HK02105192.3A patent/HK1043321B/en not_active IP Right Cessation
- 2000-04-26 AT AT00921047T patent/ATE281167T1/de active
- 2000-04-26 EP EP00921047.7A patent/EP1173177B2/en not_active Expired - Lifetime
- 2000-04-26 AU AU41429/00A patent/AU777915B2/en not_active Ceased
- 2000-04-26 TW TW089107899A patent/TWI230066B/zh not_active IP Right Cessation
- 2000-04-26 TR TR2001/03119T patent/TR200103119T2/xx unknown
- 2000-04-26 ES ES00921047T patent/ES2232439T3/es not_active Expired - Lifetime
- 2000-04-26 PT PT00921047T patent/PT1173177E/pt unknown
- 2000-04-26 MX MXPA01010988A patent/MXPA01010988A/es active IP Right Grant
- 2000-04-26 DE DE60015516T patent/DE60015516T2/de not_active Expired - Lifetime
- 2000-04-26 HK HK02107726.4A patent/HK1046099A1/zh unknown
- 2000-04-26 KR KR1020017013768A patent/KR20020015316A/ko not_active Ceased
- 2000-04-26 NZ NZ515339A patent/NZ515339A/xx unknown
- 2000-04-26 JP JP2000615007A patent/JP5036934B2/ja not_active Expired - Fee Related
- 2000-04-26 HU HU0200864A patent/HUP0200864A3/hu unknown
- 2000-04-26 IL IL14616200A patent/IL146162A0/xx unknown
- 2000-04-28 AR ARP000102060A patent/AR023807A1/es not_active Application Discontinuation
-
2001
- 2001-10-29 NO NO20015288A patent/NO20015288D0/no not_active Application Discontinuation
- 2001-10-29 ZA ZA200108905A patent/ZA200108905B/xx unknown
-
2012
- 2012-02-03 JP JP2012022420A patent/JP2012116857A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1190194C (zh) | 2005-02-23 |
| NZ515339A (en) | 2004-02-27 |
| ZA200108905B (en) | 2002-12-24 |
| EP1173177B1 (en) | 2004-11-03 |
| NO20015288L (no) | 2001-10-29 |
| CZ20013769A3 (cs) | 2002-03-13 |
| ES2232439T3 (es) | 2005-06-01 |
| PT1173177E (pt) | 2005-03-31 |
| CN1353608A (zh) | 2002-06-12 |
| ATE281167T1 (de) | 2004-11-15 |
| KR20020015316A (ko) | 2002-02-27 |
| JP2012116857A (ja) | 2012-06-21 |
| HUP0200864A3 (en) | 2004-07-28 |
| HK1046099A1 (zh) | 2002-12-27 |
| HK1043321A1 (en) | 2002-09-13 |
| AU4142900A (en) | 2000-11-17 |
| NO20015288D0 (no) | 2001-10-29 |
| EP1173177A1 (en) | 2002-01-23 |
| CA2372448A1 (en) | 2000-11-09 |
| MXPA01010988A (es) | 2004-04-21 |
| JP5036934B2 (ja) | 2012-09-26 |
| BR0011225A (pt) | 2002-03-19 |
| HUP0200864A2 (hu) | 2002-07-29 |
| AU777915B2 (en) | 2004-11-04 |
| HK1043321B (en) | 2005-07-15 |
| WO2000066122A1 (en) | 2000-11-09 |
| TR200103119T2 (tr) | 2002-04-22 |
| TWI230066B (en) | 2005-04-01 |
| JP2002543132A (ja) | 2002-12-17 |
| DE60015516T2 (de) | 2005-12-01 |
| DE60015516D1 (de) | 2004-12-09 |
| EP1173177B2 (en) | 2014-03-05 |
| AR023807A1 (es) | 2002-09-04 |
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