IL145406A0 - Melanocortin receptor ligands - Google Patents
Melanocortin receptor ligandsInfo
- Publication number
- IL145406A0 IL145406A0 IL14540600A IL14540600A IL145406A0 IL 145406 A0 IL145406 A0 IL 145406A0 IL 14540600 A IL14540600 A IL 14540600A IL 14540600 A IL14540600 A IL 14540600A IL 145406 A0 IL145406 A0 IL 145406A0
- Authority
- IL
- Israel
- Prior art keywords
- receptor ligands
- melanocortin receptor
- melanocortin
- ligands
- receptor
- Prior art date
Links
- 102000004378 Melanocortin Receptors Human genes 0.000 title 1
- 108090000950 Melanocortin Receptors Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
- C07K14/685—Alpha-melanotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/68—Melanocyte-stimulating hormone [MSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pregnancy & Childbirth (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12667399P | 1999-03-29 | 1999-03-29 | |
| PCT/US2000/007473 WO2000058361A1 (fr) | 1999-03-29 | 2000-03-21 | Ligands du recepteur de melanocortine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL145406A0 true IL145406A0 (en) | 2002-06-30 |
Family
ID=22426131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14540600A IL145406A0 (en) | 1999-03-29 | 2000-03-21 | Melanocortin receptor ligands |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US6613874B1 (fr) |
| EP (1) | EP1165613B1 (fr) |
| JP (1) | JP2002542159A (fr) |
| KR (2) | KR100519201B1 (fr) |
| CN (1) | CN1249086C (fr) |
| AR (1) | AR023201A1 (fr) |
| AT (1) | ATE393783T1 (fr) |
| AU (1) | AU763510B2 (fr) |
| BR (1) | BR0009497A (fr) |
| CA (1) | CA2368431C (fr) |
| CO (1) | CO5170531A1 (fr) |
| CZ (1) | CZ20013407A3 (fr) |
| DE (1) | DE60038734T2 (fr) |
| DK (1) | DK1165613T3 (fr) |
| ES (1) | ES2304345T3 (fr) |
| HK (1) | HK1044954B (fr) |
| HU (1) | HUP0202203A3 (fr) |
| ID (1) | ID30262A (fr) |
| IL (1) | IL145406A0 (fr) |
| MA (1) | MA25403A1 (fr) |
| MX (1) | MXPA01009881A (fr) |
| MY (1) | MY126585A (fr) |
| NO (1) | NO20014568L (fr) |
| NZ (1) | NZ514141A (fr) |
| PE (1) | PE20001641A1 (fr) |
| PL (1) | PL350095A1 (fr) |
| PT (1) | PT1165613E (fr) |
| RU (1) | RU2213098C2 (fr) |
| SA (1) | SA00210192B1 (fr) |
| SK (1) | SK13082001A3 (fr) |
| TR (1) | TR200102765T2 (fr) |
| TW (1) | TWI250990B (fr) |
| WO (1) | WO2000058361A1 (fr) |
| ZA (1) | ZA200107411B (fr) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
| JP2003505435A (ja) | 1999-06-04 | 2003-02-12 | メルク エンド カムパニー インコーポレーテッド | メラノコルチン−4受容体ゴニストとしての置換ピペリジン |
| US7235625B2 (en) | 1999-06-29 | 2007-06-26 | Palatin Technologies, Inc. | Multiple agent therapy for sexual dysfunction |
| JP2003534240A (ja) * | 2000-01-18 | 2003-11-18 | メルク エンド カムパニー インコーポレーテッド | 強力な選択的メラノコルチン−4受容体アンタゴニストとなる環状ペプチド |
| AU2001284026B2 (en) | 2000-08-30 | 2007-03-01 | F. Hoffmann-La Roche Ag | Cyclic peptides having melanocortin-4 receptor agonist activity |
| HUP0303085A2 (hu) * | 2000-09-27 | 2003-12-29 | The Procter & Gamble Co. | Melanokortin receptor ligandumok és ezeket tartalmazó gyógyszerkészítmények |
| AU2002238106A1 (en) | 2001-02-13 | 2002-08-28 | Palatin Technologies, Inc. | Melanocortin metallopeptides for treatment of sexual dysfunction |
| US7342089B2 (en) * | 2001-07-11 | 2008-03-11 | Palatin Technologies, Inc. | Cyclic peptides for treatment for cachexia |
| AU2002322466B2 (en) | 2001-07-11 | 2007-08-30 | Palatin Technologies, Inc. | Linear and cyclic melanocortin receptor-specific peptides |
| US7345144B2 (en) * | 2001-07-11 | 2008-03-18 | Palatin Technologies, Inc. | Cyclic peptides for treatment of cachexia |
| US20030195187A1 (en) * | 2002-02-04 | 2003-10-16 | Chiron Corporation | Guanidino compounds |
| US7034004B2 (en) * | 2002-05-07 | 2006-04-25 | University Of Florida | Peptides and methods for the control of obesity |
| US7323462B2 (en) | 2002-12-10 | 2008-01-29 | Pfizer Inc. | Morpholine dopamine agonists |
| JP2006527773A (ja) * | 2003-06-19 | 2006-12-07 | イーライ リリー アンド カンパニー | メラノコルチン受容体4(mc4)作用薬とその用途 |
| EP1644022A1 (fr) * | 2003-06-19 | 2006-04-12 | Eli Lilly And Company | Utilisation de peptides agonistes du recepteur de la melanocortine-3 (mc3r) |
| KR20060089874A (ko) * | 2003-09-30 | 2006-08-09 | 노보 노르디스크 에이/에스 | 신규 멜라노코르틴 수용체 작용제 |
| CN107090025A (zh) * | 2003-11-05 | 2017-08-25 | 达纳-法伯癌症研究所股份有限公司 | 稳定的α螺旋肽及其用途 |
| AU2015201062B2 (en) * | 2003-11-05 | 2017-03-09 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| ES2397241T3 (es) | 2004-01-21 | 2013-03-05 | Novo Nordisk Health Care Ag | Conjugación de péptidos mediante transglutaminasa |
| US6974187B2 (en) * | 2004-01-28 | 2005-12-13 | Tachi-S Co., Ltd. | Vehicle seat structure |
| CA2557739A1 (fr) * | 2004-03-29 | 2005-11-03 | Eli Lilly And Company | Utilisations de peptides agonistes du recepteur de la melanocortine 4 (mc4r) administres par perfusion continue |
| WO2006041769A2 (fr) * | 2004-10-05 | 2006-04-20 | Merck & Co., Inc. | Procedes de traitement d'un abus d'une substance d'une addiction a cette substance |
| WO2006060873A1 (fr) * | 2004-12-09 | 2006-06-15 | Prince Henry's Institute Of Medical Research | Procede de restauration de la fonction reproductrice |
| WO2006073772A1 (fr) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Peptides agonistes de mc4r ou de mc3r lies a un polyethyleneglycol |
| WO2006073771A2 (fr) * | 2005-01-05 | 2006-07-13 | Eli Lilly And Company | Peptides d'agonistes mc4r ou mc3r lies au polyethyleneglycol |
| US20070021433A1 (en) | 2005-06-03 | 2007-01-25 | Jian-Qiang Fan | Pharmacological chaperones for treating obesity |
| US7754691B1 (en) | 2005-07-07 | 2010-07-13 | Palatin Technologies, Inc. | Linear melanocortin receptor-specific peptides for cachexia |
| AU2006269321A1 (en) * | 2005-07-08 | 2007-01-18 | Ipsen Pharma S.A.S. | Ligands of melanocortin receptors |
| HUE031731T2 (en) * | 2005-07-08 | 2017-07-28 | Ipsen Pharma | Melanocortin receptor ligands |
| EP1968995A1 (fr) * | 2005-12-30 | 2008-09-17 | F. Hoffmann-la Roche AG | Procede de synthese de peptides contenant arginine |
| JP5444523B2 (ja) | 2006-06-09 | 2014-03-19 | シンアクト ファーマ アンパーツゼルスカブ | フェニルピロールアミノグアニヂン誘導体 |
| US7981998B2 (en) | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| WO2008076904A1 (fr) * | 2006-12-14 | 2008-06-26 | Aileron Therapeutics, Inc. | Systèmes de macrocyclisation bis-sulfhydryle |
| WO2008095063A1 (fr) | 2007-01-31 | 2008-08-07 | Dana-Farber Cancer Institute, Inc. | Peptides p53 stabilisés et utilisations de ceux-ci |
| EP2564862B1 (fr) | 2007-02-23 | 2017-08-02 | Aileron Therapeutics, Inc. | Acides aminés substitués pour la préparation de peptides macrocycliques réticulés avec de triazole |
| ES2430067T3 (es) | 2007-03-28 | 2013-11-18 | President And Fellows Of Harvard College | Polipéptidos cosidos |
| JP5250026B2 (ja) | 2007-05-25 | 2013-07-31 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | ヒダントインで修飾したメラノコルチン受容体リガンド |
| CN101980718A (zh) * | 2008-02-08 | 2011-02-23 | 爱勒让治疗公司 | 治疗性的拟肽大环化合物 |
| US20110144303A1 (en) * | 2008-04-08 | 2011-06-16 | Aileron Therapeutics, Inc. | Biologically Active Peptidomimetic Macrocycles |
| EP2310407A4 (fr) * | 2008-04-08 | 2011-09-14 | Aileron Therapeutics Inc | Macrocycles peptidomimétiques biologiquement actifs |
| UY31877A (es) * | 2008-06-09 | 2010-01-29 | Palatin Technologies Inc | Péptidos específicos de los receptores de melanocortina para el tratamiento de la obesidad / 669 |
| AU2009257631B2 (en) | 2008-06-09 | 2014-07-24 | Palatin Technologies, Inc. | Melanocortin receptor-specific peptides for treatment of sexual dysfunction |
| WO2010011313A2 (fr) * | 2008-07-23 | 2010-01-28 | President And Fellows Of Harvard College | Ligature de polypeptides agrafés |
| EP2342221B1 (fr) | 2008-09-22 | 2018-11-07 | Aileron Therapeutics, Inc. | Procédés pour préparer des compositions de polypeptide purifié |
| BRPI1006139A2 (pt) | 2009-01-14 | 2017-05-30 | Aileron Therapeutics Inc | macrociclos peptidomiméticos |
| AU2010259008C1 (en) | 2009-06-08 | 2016-04-21 | Palatin Technologies, Inc. | Melanocortin receptor-specific peptides |
| UY32690A (es) | 2009-06-08 | 2011-01-31 | Astrazeneca Ab | Péptidos específicos para receptores de melanocortina |
| EP2440572B1 (fr) | 2009-06-08 | 2017-04-05 | Palatin Technologies, Inc. | Peptides spécifiques des récepteurs aux mélanocortines à pont lactame |
| CA2768299C (fr) | 2009-07-13 | 2018-03-20 | President And Fellows Of Harvard College | Peptides bifonctionnels inseres et leurs utilisations |
| CN102712675A (zh) | 2009-09-22 | 2012-10-03 | 爱勒让治疗公司 | 拟肽大环化合物 |
| RU2012125033A (ru) * | 2009-11-16 | 2014-01-20 | Ипсен Фарма С.А.С. | СПОСОБ СИНТЕЗА Ас-Arg-ЦИКЛО(Cys-D-Ala-His-D-Phe-Arg-Trp-Cys)-NH2 |
| CA2781405A1 (fr) | 2009-11-23 | 2011-05-26 | Palatin Technologies, Inc. | Peptides lineaires specifiques du recepteur de la melanocortine-1 |
| CA2781402C (fr) | 2009-11-23 | 2017-03-21 | Palatin Technologies, Inc. | Peptides cycliques specifiques du recepteur de la melanocortine-1 |
| CN101824415A (zh) * | 2010-03-31 | 2010-09-08 | 华东师范大学 | 黑素皮质1型受体基因的snp及其应用 |
| DK2603600T3 (da) | 2010-08-13 | 2019-03-04 | Aileron Therapeutics Inc | Peptidomimetiske makrocyklusser |
| US8957026B2 (en) | 2010-09-22 | 2015-02-17 | President And Fellows Of Harvard College | Beta-catenin targeting peptides and uses thereof |
| US9018395B2 (en) | 2011-01-27 | 2015-04-28 | Université de Montréal | Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators |
| US9487562B2 (en) | 2011-06-17 | 2016-11-08 | President And Fellows Of Harvard College | Stabilized polypeptides as regulators of RAB GTPase function |
| CA2852468A1 (fr) | 2011-10-18 | 2013-04-25 | Aileron Therapeutics, Inc. | Macrocycles peptidomimetiques |
| SG10201606775YA (en) | 2012-02-15 | 2016-10-28 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
| HK1205454A1 (en) | 2012-02-15 | 2015-12-18 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| WO2014052647A2 (fr) | 2012-09-26 | 2014-04-03 | President And Fellows Of Harvard College | Peptides agrafés bloqués par la proline et leurs utilisations |
| CA2887285A1 (fr) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Acides amines disubstitues et procedes de preparation et d'utilisation de ceux-ci |
| CN110105434B (zh) | 2013-03-13 | 2024-09-17 | 哈佛大学的校长及成员们 | 钉合且缝合的多肽及其用途 |
| BR112015031277A2 (pt) | 2013-06-14 | 2017-09-19 | Harvard College | Moduladores do receptor de insulina de polipeptídeos estabilizados, análogos de insulina, composições farmacêuticas compreendendo os referidos polipeptídeos e métodos de preparação e usos dos mesmos |
| CA2949535C (fr) | 2014-05-21 | 2023-09-12 | President And Fellows Of Harvard College | Peptides inhibiteurs de ras et leurs utilisations |
| JP2017533889A (ja) | 2014-09-24 | 2017-11-16 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | ペプチド模倣大環状分子およびその使用 |
| SG10201902598VA (en) | 2014-09-24 | 2019-04-29 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and formulations thereof |
| JP2018516844A (ja) | 2015-03-20 | 2018-06-28 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | ペプチド模倣大環状分子およびその使用 |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| EP3347372A4 (fr) | 2015-09-10 | 2019-09-04 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques en tant que modulateurs de mcl-1 |
| EP4119140B1 (fr) | 2019-05-10 | 2025-06-25 | SynAct Pharma ApS | Dérivés de phénylpyrrole aminoguanidine en combinaison avec le méthotrexate pour le traitement des maladies arthritiques |
| CN110681362B (zh) * | 2019-09-26 | 2020-09-11 | 浙江大学 | 以羧基和吲哚基为功能基团的混合模式层析介质 |
| US11590209B2 (en) | 2020-01-21 | 2023-02-28 | Palatin Technologies, Inc. | Use of bremelanotide in patients with controlled hypertension |
| US11932628B2 (en) | 2021-01-04 | 2024-03-19 | Regents Of The University Of Minnesota | Selective small molecule peptidomimetic melanocortin ligands |
| EP4684835A2 (fr) | 2021-06-21 | 2026-01-28 | SynAct Pharma ApS | Sels de phényl pyrrole aminoguanidine et formulations associées |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5462927A (en) | 1985-04-30 | 1995-10-31 | The Administrators Of The Tulane Educational Fund | Peptides aiding nerve regeneration |
| DE3851002T2 (de) | 1987-05-22 | 1995-02-02 | University Patents, Inc., Westport, Conn. | Lineare und zyklische Analoge von alpha-MSH-Fragmenten mit ausserordentlicher Wirkung. |
| WO1989002897A1 (fr) | 1987-09-24 | 1989-04-06 | The Administrators Of The Tulane Educational Fund | Peptides a usage therapeutique |
| ZA908610B (en) | 1989-11-03 | 1991-08-28 | Univ Tulane | Peptides aiding nerve regeneration |
| CA2061246A1 (fr) | 1991-02-15 | 1992-08-16 | Mitsuhiro Wakimasu | Peptides, leur production et leur utilisation |
| DE69220861T2 (de) | 1991-08-13 | 1997-11-20 | Takeda Chemical Industries Ltd | Zyklische Peptide und ihre Verwendung |
| RU2096415C1 (ru) * | 1991-09-30 | 1997-11-20 | Дзе Дюпон Мерк Фармасьютикал Компани | Циклические пептиды или их фармацевтически приемлемые соли, фармацевтическая композиция |
| EP0552417B1 (fr) | 1991-11-19 | 1999-07-07 | Takeda Chemical Industries, Ltd. | Peptides cycliques et leurs utilisations |
| EP0547317A1 (fr) | 1991-12-19 | 1993-06-23 | Takeda Chemical Industries, Ltd. | Antagonistes d'endothéline |
| DE9203901U1 (de) | 1992-03-24 | 1992-07-16 | Croon & Lucke Maschinenfabrik Gmbh, 7947 Mengen | Gestell zum Lagern von flächigen Werkstücken |
| US5569741A (en) | 1992-07-27 | 1996-10-29 | Biomeasure, Inc. | Cyclic octapeptide neuromedin B receptor antagonists |
| ES2162822T3 (es) | 1992-07-27 | 2002-01-16 | Univ Tulane | Utilizacion de octapeptidos para el tratamiento de enfermedades asociadas con el receptor de neuromedina b. |
| AU673731B2 (en) | 1993-06-03 | 1996-11-21 | Banyu Pharmaceutical Co., Ltd. | Novel endothelin antagonistic peptide |
| EP0714909A1 (fr) | 1994-12-01 | 1996-06-05 | Takeda Chemical Industries, Ltd. | Composition pour la prévention et le traitement de maladies de la circulation pulmonaire |
| US5731408A (en) * | 1995-04-10 | 1998-03-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Peptides having potent antagonist and agonist bioactivities at melanocortin receptors |
| US6054556A (en) * | 1995-04-10 | 2000-04-25 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Melanocortin receptor antagonists and agonists |
| EP0822939A1 (fr) | 1995-04-28 | 1998-02-11 | Takeda Chemical Industries, Ltd. | Antagonistes des recepteurs lh-rh pentapeptidiques cycliques |
| US5817750A (en) | 1995-08-28 | 1998-10-06 | La Jolla Cancer Research Foundation | Structural mimics of RGD-binding sites |
| ATE233098T1 (de) | 1996-06-11 | 2003-03-15 | Novartis Ag | Kombination eines somatostatin analogs und eines rapamycins |
| JP3947228B2 (ja) | 1996-06-25 | 2007-07-18 | 株式会社日清製粉グループ本社 | 環状デプシペプチドおよびこれを有効成分とする医薬 |
| EP0815870A3 (fr) | 1996-06-27 | 2000-05-03 | Takeda Chemical Industries, Ltd. | Composition de prophylaxie et de traitement d'infarction cérébrale |
| US5770380A (en) | 1996-09-13 | 1998-06-23 | University Of Pittsburgh | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold |
| IT1288388B1 (it) | 1996-11-19 | 1998-09-22 | Angeletti P Ist Richerche Bio | Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia |
| CA2275442A1 (fr) | 1996-12-17 | 1998-06-25 | Quadrant Holdings Cambridge Limited | Melanocortines |
| SE9700620D0 (sv) * | 1997-02-21 | 1997-02-21 | Wapharm Ab | Cykliska peptider med selektivitet för MSH-receptor subtyper |
| GB9827500D0 (en) | 1998-12-14 | 1999-02-10 | Wapharm Ab | Compounds for control of eating, growth and body weight |
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2000
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- 2000-03-21 ES ES00919500T patent/ES2304345T3/es not_active Expired - Lifetime
- 2000-03-21 CZ CZ20013407A patent/CZ20013407A3/cs unknown
- 2000-03-21 SK SK1308-2001A patent/SK13082001A3/sk unknown
- 2000-03-21 EP EP00919500A patent/EP1165613B1/fr not_active Expired - Lifetime
- 2000-03-21 ID IDW00200102111A patent/ID30262A/id unknown
- 2000-03-21 NZ NZ514141A patent/NZ514141A/xx unknown
- 2000-03-21 PL PL00350095A patent/PL350095A1/xx not_active Application Discontinuation
- 2000-03-21 HK HK02104687.8A patent/HK1044954B/en not_active IP Right Cessation
- 2000-03-21 CA CA002368431A patent/CA2368431C/fr not_active Expired - Fee Related
- 2000-03-21 TR TR2001/02765T patent/TR200102765T2/xx unknown
- 2000-03-21 BR BR0009497-8A patent/BR0009497A/pt not_active IP Right Cessation
- 2000-03-21 AU AU40179/00A patent/AU763510B2/en not_active Ceased
- 2000-03-21 JP JP2000608653A patent/JP2002542159A/ja active Pending
- 2000-03-21 PT PT00919500T patent/PT1165613E/pt unknown
- 2000-03-21 KR KR1020047019303A patent/KR100558131B1/ko not_active Expired - Fee Related
- 2000-03-21 DE DE60038734T patent/DE60038734T2/de not_active Expired - Fee Related
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- 2000-03-21 WO PCT/US2000/007473 patent/WO2000058361A1/fr not_active Ceased
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- 2000-03-28 CO CO00022068A patent/CO5170531A1/es not_active Application Discontinuation
- 2000-03-28 TW TW089105726A patent/TWI250990B/zh not_active IP Right Cessation
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- 2000-03-29 PE PE2000000267A patent/PE20001641A1/es not_active Application Discontinuation
- 2000-03-29 US US09/537,789 patent/US6613874B1/en not_active Expired - Fee Related
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2001
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- 2001-09-26 MA MA26340A patent/MA25403A1/fr unknown
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2003
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