IL132279A0 - Prevention of breast cancer with selective estrogen receptor modulators - Google Patents
Prevention of breast cancer with selective estrogen receptor modulatorsInfo
- Publication number
- IL132279A0 IL132279A0 IL13227998A IL13227998A IL132279A0 IL 132279 A0 IL132279 A0 IL 132279A0 IL 13227998 A IL13227998 A IL 13227998A IL 13227998 A IL13227998 A IL 13227998A IL 132279 A0 IL132279 A0 IL 132279A0
- Authority
- IL
- Israel
- Prior art keywords
- prevention
- breast cancer
- estrogen receptor
- receptor modulators
- selective estrogen
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title 1
- 208000026310 Breast neoplasm Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 239000000333 selective estrogen receptor modulator Substances 0.000 title 1
- 229940095743 selective estrogen receptor modulator Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4311897P | 1997-04-09 | 1997-04-09 | |
| PCT/US1998/006989 WO1998045286A1 (en) | 1997-04-09 | 1998-04-07 | Prevention of breast cancer with selective estrogen receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL132279A0 true IL132279A0 (en) | 2001-03-19 |
Family
ID=21925594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13227998A IL132279A0 (en) | 1997-04-09 | 1998-04-07 | Prevention of breast cancer with selective estrogen receptor modulators |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0975628A4 (en) |
| JP (1) | JP2001518897A (en) |
| KR (1) | KR20010006215A (en) |
| CN (1) | CN1259945A (en) |
| AU (1) | AU6957398A (en) |
| CA (1) | CA2286207A1 (en) |
| EA (1) | EA199900910A1 (en) |
| HU (1) | HUP0001845A2 (en) |
| ID (1) | ID23653A (en) |
| IL (1) | IL132279A0 (en) |
| NO (1) | NO994902L (en) |
| PL (1) | PL336206A1 (en) |
| TR (1) | TR199903244T2 (en) |
| WO (1) | WO1998045286A1 (en) |
| ZA (1) | ZA982818B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6653479B1 (en) | 1999-07-29 | 2003-11-25 | Eli Lilly And Company | Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride |
| US6610706B1 (en) | 1999-07-29 | 2003-08-26 | Eli Lilly And Company | Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride |
| NZ585389A (en) | 2007-10-16 | 2011-10-28 | Repros Therapeutics Inc | Trans-clomiphene for metabolic syndrome |
| ES2681023T3 (en) | 2012-02-29 | 2018-09-11 | Repros Therapeutics Inc. | Combination therapy to treat androgen deficit |
| ES2671516T3 (en) | 2013-02-19 | 2018-06-06 | Novartis Ag | Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders |
| GB201311888D0 (en) * | 2013-07-03 | 2013-08-14 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| US11633382B2 (en) | 2015-11-10 | 2023-04-25 | Paracrine Therapeutics Ab | Treatment of ER-negative breast cancer with an PDGF-CC inhibitor and anti-estrogen |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5510357A (en) * | 1995-02-28 | 1996-04-23 | Eli Lilly And Company | Benzothiophene compounds as anti-estrogenic agents |
| JP3989569B2 (en) * | 1995-02-28 | 2007-10-10 | イーライ リリー アンド カンパニー | Benzothiophene compounds, intermediates, compositions and methods |
| US5731342A (en) * | 1996-02-22 | 1998-03-24 | Eli Lilly And Company | Benzothiophenes, formulations containing same, and methods |
-
1998
- 1998-04-02 ZA ZA9802818A patent/ZA982818B/en unknown
- 1998-04-07 CN CN98805957A patent/CN1259945A/en active Pending
- 1998-04-07 IL IL13227998A patent/IL132279A0/en unknown
- 1998-04-07 EA EA199900910A patent/EA199900910A1/en unknown
- 1998-04-07 AU AU69573/98A patent/AU6957398A/en not_active Abandoned
- 1998-04-07 EP EP98915368A patent/EP0975628A4/en not_active Withdrawn
- 1998-04-07 TR TR1999/03244T patent/TR199903244T2/en unknown
- 1998-04-07 PL PL98336206A patent/PL336206A1/en unknown
- 1998-04-07 HU HU0001845A patent/HUP0001845A2/en unknown
- 1998-04-07 CA CA002286207A patent/CA2286207A1/en not_active Abandoned
- 1998-04-07 ID IDW991189A patent/ID23653A/en unknown
- 1998-04-07 KR KR1019997009295A patent/KR20010006215A/en not_active Withdrawn
- 1998-04-07 WO PCT/US1998/006989 patent/WO1998045286A1/en not_active Ceased
- 1998-04-07 JP JP54309098A patent/JP2001518897A/en active Pending
-
1999
- 1999-10-08 NO NO994902A patent/NO994902L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ID23653A (en) | 2000-05-11 |
| KR20010006215A (en) | 2001-01-26 |
| CN1259945A (en) | 2000-07-12 |
| EA199900910A1 (en) | 2000-04-24 |
| NO994902L (en) | 1999-12-07 |
| PL336206A1 (en) | 2000-06-05 |
| WO1998045286A1 (en) | 1998-10-15 |
| NO994902D0 (en) | 1999-10-08 |
| AU6957398A (en) | 1998-10-30 |
| ZA982818B (en) | 1999-10-04 |
| CA2286207A1 (en) | 1998-10-15 |
| EP0975628A4 (en) | 2001-03-21 |
| JP2001518897A (en) | 2001-10-16 |
| HUP0001845A2 (en) | 2001-06-28 |
| TR199903244T2 (en) | 2000-05-22 |
| EP0975628A1 (en) | 2000-02-02 |
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