IL132153A0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number: IL132153A0
Authority: IL; Israel
Prior art keywords: pct; date; novel compounds; sec; pub
Prior art date: 1997-04-15

Application number

IL13215398A

Other languages

English (en)

Original Assignee

Astra Pharma Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-15

Filing date

1998-04-07

Publication date

2001-03-19

1998-04-07 Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod

2001-03-19 Publication of IL132153A0 publication Critical patent/IL132153A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Orthopedic Medicine & Surgery (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
AIDS & HIV (AREA)
Oncology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Use Of Switch Circuits For Exchanges And Methods Of Control Of Multiplex Exchanges (AREA)

IL13215398A 1997-04-15 1998-04-07 Novel compounds IL132153A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9701398A SE9701398D0 (sv)	1997-04-15	1997-04-15	Novel compounds
PCT/SE1998/000640 WO1998046606A1 (en)	1997-04-15	1998-04-07	Novel compounds

Publications (1)

Publication Number	Publication Date
IL132153A0 true IL132153A0 (en)	2001-03-19

Family

ID=20406576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13215398A IL132153A0 (en)	1997-04-15	1998-04-07	Novel compounds

Country Status (21)

Country	Link
US (1)	US6028074A (pt)
EP (1)	EP0975636B1 (pt)
JP (1)	JP2001520645A (pt)
KR (1)	KR20010006350A (pt)
CN (1)	CN1259951A (pt)
AT (1)	ATE245648T1 (pt)
AU (1)	AU733066B2 (pt)
BR (1)	BR9808540A (pt)
CA (1)	CA2286078A1 (pt)
DE (1)	DE69816608T2 (pt)
EE (1)	EE9900465A (pt)
HU (1)	HUP0002104A3 (pt)
ID (1)	ID22746A (pt)
IL (1)	IL132153A0 (pt)
IS (1)	IS5198A (pt)
NO (1)	NO995006D0 (pt)
PL (1)	PL336230A1 (pt)
SE (1)	SE9701398D0 (pt)
SK (1)	SK135699A3 (pt)
TR (1)	TR199902538T2 (pt)
WO (1)	WO1998046606A1 (pt)

Families Citing this family (52)

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SE9801399D0 (sv)	1998-04-21	1998-04-21	Astra Pharma Prod	Method and apparatus for filling containers
GC0000177A (en) *	1998-12-17	2006-03-29	Smithkline Beecham	Thrombopoietin mimetics
CY2010012I2 (el)	2000-05-25	2020-05-29	Novartis Ag	Μιμητικα θρομβοποιητινης
JP2004527541A (ja)	2001-03-01	2004-09-09	スミスクライン・ビーチャム・コーポレイション	トロンボポエチン模倣物
CA2459161A1 (en)	2001-08-31	2003-03-13	The Rockefeller University	Phosphodiesterase activity and regulation of phosphodiesterase 1b-mediated signaling in brain
AR040083A1 (es)	2002-05-22	2005-03-16	Smithkline Beecham Corp	Compuesto bis-(monoetanolamina) del acido 3'-[(2z)-[1-(3,4-dimetilfenil) -1,5-dihidro-3-metil-5-oxo-4h-pirazol-4-iliden] hidrazino] -2'-hidroxi-[1,1'-bifenil]-3-carboxilico, procedimiento para prepararlo, composicion farmaceutica que lo comprende, procedimiento para preparar dicha composicion farmac
TW200526638A (en)	2003-10-22	2005-08-16	Smithkline Beecham Corp	2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline
WO2006127918A2 (en) *	2005-05-24	2006-11-30	Ott David M	Personal care and medicinal products incorporating bound organosulfur groups
CN101248050B (zh)	2005-06-06	2013-07-17	武田药品工业株式会社	有机化合物
MX2008015489A (es)	2006-06-06	2009-01-13	Intra Cellular Therapies Inc	Compuestos organicos.
WO2008063505A1 (en)	2006-11-13	2008-05-29	Intra-Cellular Therapies, Inc.	Organic compounds
US9006258B2 (en)	2006-12-05	2015-04-14	Intra-Cellular Therapies, Inc.	Method of treating female sexual dysfunction with a PDE1 inhibitor
ECSP077628A (es)	2007-05-03	2008-12-30	Smithkline Beechman Corp	Nueva composición farmacéutica
KR20120012831A (ko)	2007-12-06	2012-02-10	인트라-셀룰라 써래피스, 인코퍼레이티드.	유기 화합물
CN101969774A (zh) *	2007-12-06	2011-02-09	细胞内治疗公司	有机化合物
US8633180B2 (en)	2008-12-06	2014-01-21	Intra-Cellular Therapies, Inc.	Organic compounds
EA201170768A1 (ru)	2008-12-06	2012-05-30	Интра-Селлулар Терапиз, Инк.	Органические соединения
US8859564B2 (en) *	2008-12-06	2014-10-14	Intra-Cellular Therapies, Inc.	Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione derivatives useful as inhibitors of phosphodiesterase 1
MX2011005933A (es)	2008-12-06	2011-12-16	Intra Cellular Therapies Inc	Compuestos organicos.
JP5784501B2 (ja)	2008-12-06	2015-09-24	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	有機化合物
WO2010065153A1 (en)	2008-12-06	2010-06-10	Intra-Cellular Therapies, Inc.	Organic compounds
EP2400970A4 (en)	2009-02-25	2012-07-18	Intra Cellular Therapies Inc	PDE-1-HEMMER FOR EYE DRESSING
BRPI1013559A2 (pt) *	2009-03-23	2016-04-12	Glenmark Pharmaceuticals Sa	compostos, composição farmacêutica, método de tratamento de doença ou condição associada à função trpa1 e respectivos usos
SG184766A1 (en)	2009-03-23	2012-10-30	Glenmark Pharmaceuticals Sa	Isothiazolo-pyrimidinedione derivatives as trpa1 modulators
US8623880B2 (en)	2009-03-23	2014-01-07	Glenmark Pharmaceuticals S.A.	Fused pyrimidine-dione derivatives as TRPA1 modulators
CN102361874A (zh)	2009-03-23	2012-02-22	格兰马克药品股份有限公司	作为trpa1调节剂的呋喃并嘧啶二酮衍生物
WO2010132127A1 (en)	2009-05-13	2010-11-18	Intra-Cellular Therapies, Inc.	Organic compounds
AU2010254046C1 (en)	2009-05-29	2014-03-06	Novartis Ag	Methods of administration of thrombopoietin agonist compounds
WO2011016861A2 (en)	2009-08-05	2011-02-10	Intra-Cellular Therapies, Inc.	Novel regulatory proteins and inhibitors
TW201206937A (en)	2010-05-31	2012-02-16	Intra Cellular Therapies Inc	Organic compounds
EP2590657A4 (en)	2010-05-31	2014-02-12	Intra Cellular Therapies Inc	ORGANIC CONNECTIONS
EP2576551A4 (en)	2010-05-31	2014-04-16	Intra Cellular Therapies Inc	ORGANIC CONNECTIONS
EP2575817A4 (en)	2010-05-31	2014-01-08	Intra Cellular Therapies Inc	ORGANIC CONNECTIONS
WO2012171016A1 (en)	2011-06-10	2012-12-13	Intra-Cellular Therapies, Inc.	Organic compounds
IN2014MN02467A (pt)	2012-06-08	2015-07-10	Glenmark Pharmaceuticals Sa
US9801882B2 (en)	2013-02-17	2017-10-31	Intra-Cellular Therapies, Inc.	Phosphodiesterase-1 inhibitors and their use in treatment of cardiovascular diseases
PL2970279T3 (pl)	2013-03-15	2021-05-31	Intra-Cellular Therapies, Inc.	Związki organiczne
EP2968338B1 (en)	2013-03-15	2019-01-09	Intra-Cellular Therapies, Inc.	Pde1 inhibitors for use in the treatment and/or prevention of cns injuries, and pns diseases, disorders or injuries
JP6696904B2 (ja)	2014-01-08	2020-05-20	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	製剤および医薬組成物
WO2015196186A1 (en)	2014-06-20	2015-12-23	Intra-Cellular Therapies, Inc.	Organic compounds
EP3177627B1 (en)	2014-08-07	2019-07-24	Intra-Cellular Therapies, Inc.	Imidazo[1,2-a]-pyrazolo[4,3-e]-pyrimidin-4-one derivatives with pde1 inhibiting activity
US10285992B2 (en)	2014-08-07	2019-05-14	Intra-Cellular Therapies, Inc.	Combinations of PDE1 inhibitors and NEP inhibitors and associated methods
US9546175B2 (en)	2014-08-07	2017-01-17	Intra-Cellular Therapies, Inc.	Organic compounds
JP6596080B2 (ja)	2014-09-17	2019-10-23	イントラ−セルラー・セラピーズ・インコーポレイテッド	化合物および方法
HK1243935A1 (zh)	2014-12-06	2018-07-27	Intra-Cellular Therapies, Inc.	有机化合物
WO2016090380A1 (en)	2014-12-06	2016-06-09	Intra-Cellular Therapies, Inc.	Organic compounds
WO2017172795A1 (en)	2016-03-28	2017-10-05	Intra-Cellular Therapies, Inc.	Novel compositions and methods
JP6964099B2 (ja) *	2016-06-23	2021-11-10	エフ.ホフマン−ラロシュアーゲーF. Hoffmann−La Roche Aktiengesellschaft	新規［１，２，３］トリアゾロ［４，５−ｄ］ピリミジン誘導体
US11291666B2 (en)	2016-09-12	2022-04-05	Intra-Cellular Therapies, Inc.	Uses
EP3746081A4 (en)	2018-01-31	2021-10-27	Intra-Cellular Therapies, Inc.	Novel uses
US12410175B2 (en)	2019-09-03	2025-09-09	Intra-Cellular Therapies, Inc.	Compounds
US12364695B2 (en)	2020-06-02	2025-07-22	Intra-Cellular Therapies, Inc.	Methods of treating inflammatory disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1982003626A1 (en) *	1981-04-22	1982-10-28	Gauri Kailash Kumar	New derivatives of pyrazolo(3,4-d)pyrimidine,preparation method thereof and remedy containing them
US4603203A (en) *	1983-12-14	1986-07-29	Takeda Chemical Industries, Ltd.	3-aminopyrazolo[3,4-d]pyrimidine derivatives and production thereof
EP0237289A3 (en) *	1986-03-14	1988-07-27	Takeda Chemical Industries, Ltd.	Pyrazolo [3,4-d] pyrimidine derivatives, their production and use
JP2862374B2 (ja) *	1992-12-17	1999-03-03	フアイザー・インコーポレイテツド	Ｃｒｆアンタゴニスト活性を有するピラゾール及びピラゾロピリミジン
TW444018B (en) *	1992-12-17	2001-07-01	Pfizer	Pyrazolopyrimidines

1997
- 1997-04-15 SE SE9701398A patent/SE9701398D0/xx unknown
1998
- 1998-04-07 CN CN98806075A patent/CN1259951A/zh active Pending
- 1998-04-07 IL IL13215398A patent/IL132153A0/xx unknown
- 1998-04-07 PL PL98336230A patent/PL336230A1/xx unknown
- 1998-04-07 CA CA002286078A patent/CA2286078A1/en not_active Abandoned
- 1998-04-07 HU HU0002104A patent/HUP0002104A3/hu unknown
- 1998-04-07 EE EEP199900465A patent/EE9900465A/xx unknown
- 1998-04-07 AU AU70909/98A patent/AU733066B2/en not_active Ceased
- 1998-04-07 TR TR1999/02538T patent/TR199902538T2/xx unknown
- 1998-04-07 WO PCT/SE1998/000640 patent/WO1998046606A1/en not_active Ceased
- 1998-04-07 JP JP54380398A patent/JP2001520645A/ja not_active Ceased
- 1998-04-07 ID IDW991207A patent/ID22746A/id unknown
- 1998-04-07 EP EP98917859A patent/EP0975636B1/en not_active Expired - Lifetime
- 1998-04-07 KR KR1019997009435A patent/KR20010006350A/ko not_active Withdrawn
- 1998-04-07 SK SK1356-99A patent/SK135699A3/sk unknown
- 1998-04-07 BR BR9808540-9A patent/BR9808540A/pt not_active IP Right Cessation
- 1998-04-07 DE DE69816608T patent/DE69816608T2/de not_active Expired - Fee Related
- 1998-04-07 AT AT98917859T patent/ATE245648T1/de not_active IP Right Cessation
- 1998-08-07 US US09/068,304 patent/US6028074A/en not_active Expired - Fee Related
1999
- 1999-09-27 IS IS5198A patent/IS5198A/is unknown
- 1999-10-14 NO NO995006A patent/NO995006D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ID22746A (id)	1999-12-09
IS5198A (is)	1999-09-27
CN1259951A (zh)	2000-07-12
NO995006L (no)	1999-10-14
TR199902538T2 (xx)	2000-02-21
HUP0002104A3 (en)	2002-03-28
SK135699A3 (en)	2000-05-16
EP0975636B1 (en)	2003-07-23
KR20010006350A (ko)	2001-01-26
EP0975636A1 (en)	2000-02-02
PL336230A1 (en)	2000-06-19
US6028074A (en)	2000-02-22
NO995006D0 (no)	1999-10-14
CA2286078A1 (en)	1998-10-22
EE9900465A (et)	2000-04-17
SE9701398D0 (sv)	1997-04-15
JP2001520645A (ja)	2001-10-30
HUP0002104A2 (hu)	2001-01-29
WO1998046606A1 (en)	1998-10-22
AU733066B2 (en)	2001-05-03
BR9808540A (pt)	2000-05-23
ATE245648T1 (de)	2003-08-15
DE69816608D1 (de)	2003-08-28
AU7090998A (en)	1998-11-11
DE69816608T2 (de)	2004-04-15

Publication	Publication Date	Title
IL132153A0 (en)	2001-03-19	Novel compounds
PL340836A1 (en)	2001-02-26	Novel compounds
PL337126A1 (en)	2000-07-31	Novel compounds
IS5082A (is)	1999-06-14	Pýrróló[3,4-D]pýrimídínon-afleiður og notkun þeirra sem lyfja
UA66801C2 (uk)	2004-06-15	Триазоло[4,5-d]піримідинові сполуки, спосіб їх одержання (варіанти), фармацевтична композиція на їх основі та спосіб лікування порушень агрегації тромбоцитів
HUT75776A (en)	1997-05-28	Pyrazolo and pyrrolopyridines, their using, pharmaceutical compositions containing them and intermediates
PL338518A1 (en)	2000-11-06	Novel compounds
IL108520A (en)	1997-09-30	2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a\| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IL134111A0 (en)	2001-04-30	Triazolo [4,5-d] pyrimidine compounds, their use anovel compounds s medicaments, compositions containing them and processes for their preparation
ATE251908T1 (de)	2003-11-15	Zusammensetzung zur behandlung sexueller funktionsstörungen die phosphodiesterase-5 inhibitoren enthaltend
GR3034354T3 (en)	2000-12-29	IMIDAZO 1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF
ATE251162T1 (de)	2003-10-15	Triazolo(4,5-d)pyrimidin-verbindungen
AU3862997A (en)	1998-02-20	Stable derivatives of ubiquinole, processes for their production and pharmaceutical use thereof
IL88726A0 (en)	1989-07-31	Dihydrothienobenzodiazepinone derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof
HU9503099D0 (en)	1995-12-28	New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components
AU7436098A (en)	1998-11-13	Use of mizolastine for preparing a medicine for treating inflammation