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IL131986A0 - Shuffling of heterologous dna sequences - Google Patents

Shuffling of heterologous dna sequences

Info

Publication number
IL131986A0
IL131986A0 IL13198698A IL13198698A IL131986A0 IL 131986 A0 IL131986 A0 IL 131986A0 IL 13198698 A IL13198698 A IL 13198698A IL 13198698 A IL13198698 A IL 13198698A IL 131986 A0 IL131986 A0 IL 131986A0
Authority
IL
Israel
Prior art keywords
shuffling
conserved region
fragments
interest
identification
Prior art date
Application number
IL13198698A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26063733&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL131986(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL131986A0 publication Critical patent/IL131986A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13198698A 1997-03-18 1998-03-18 Shuffling of heterologous dna sequences IL131986A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK30497 1997-03-18
DK43297 1997-04-17
PCT/DK1998/000105 WO1998041623A1 (en) 1997-03-18 1998-03-18 Shuffling of heterologous dna sequences

Publications (1)

Publication Number Publication Date
IL131986A0 true IL131986A0 (en) 2001-03-19

Family

ID=26063733

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13198698A IL131986A0 (en) 1997-03-18 1998-03-18 Shuffling of heterologous dna sequences

Country Status (10)

Country Link
EP (1) EP1015575B1 (de)
JP (1) JP2001516216A (de)
AT (1) ATE468394T1 (de)
AU (1) AU738461B2 (de)
CA (1) CA2284097A1 (de)
DE (1) DE69841674D1 (de)
DK (1) DK1015575T3 (de)
IL (1) IL131986A0 (de)
NZ (1) NZ337910A (de)
WO (1) WO1998041623A1 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995017B1 (en) 1994-02-17 2006-02-07 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US20060257890A1 (en) 1996-05-20 2006-11-16 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
US7148054B2 (en) 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
EP0977869B2 (de) 1997-04-09 2008-11-12 Danisco A/S Lipase und verwendung davon zur verbesserung von teigen und backwaren
CA2313380C (en) 1997-12-08 2008-12-30 California Institute Of Technology Method for creating polynucleotide and polypeptide sequences
US7390619B1 (en) 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
EP1073670A1 (de) 1998-05-01 2001-02-07 Maxygen, Inc. Optimierung der schädlingsresistenz-gene durch dns-durchmischung
US7153655B2 (en) 1998-06-16 2006-12-26 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
US6846655B1 (en) 1998-06-29 2005-01-25 Phylos, Inc. Methods for generating highly diverse libraries
EP1104459A1 (de) 1998-08-12 2001-06-06 Maxygen, Inc. Dna-shuffling von monooxygenase genen für die herstellung von industriellen chemikalien
US6500639B2 (en) 1998-10-07 2002-12-31 Maxygen, Inc. DNA shuffling to produce nucleic acids for mycotoxin detoxification
EP1129184A1 (de) 1998-11-10 2001-09-05 Maxygen, Inc. Modifizierte adp-glukose pyrophosphorylase zur verbesserung und optimierung des phenotyps von pflanzen
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US6917882B2 (en) 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
US7024312B1 (en) 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
WO2000042561A2 (en) 1999-01-19 2000-07-20 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
IL144657A0 (en) 1999-02-11 2002-06-30 Maxygen Inc High throughput mass spectrometry
US6531316B1 (en) 1999-03-05 2003-03-11 Maxyag, Inc. Encryption of traits using split gene sequences and engineered genetic elements
WO2000061731A2 (en) * 1999-04-13 2000-10-19 Maxygen, Inc. Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
US7430477B2 (en) 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
US7115712B1 (en) 1999-12-02 2006-10-03 Maxygen, Inc. Cytokine polypeptides
EP1276900A2 (de) 2000-01-11 2003-01-22 Maxygen, Inc. Integrierte systeme und verfahren zur generierung und screening der diversität
US6248541B1 (en) 2000-04-21 2001-06-19 Genencor International, Inc. Screening under nutrient limited conditions
US6534292B1 (en) 2000-05-08 2003-03-18 Genencor International, Inc. Methods for forming recombined nucleic acids
US20020045175A1 (en) * 2000-05-23 2002-04-18 Zhen-Gang Wang Gene recombination and hybrid protein development
AU2001272978A1 (en) 2000-06-23 2002-01-08 Maxygen, Inc. Novel co-stimulatory molecules
WO2002000897A2 (en) 2000-06-23 2002-01-03 Maxygen, Inc. Novel chimeric promoters
AU2001267333A1 (en) 2000-06-26 2002-01-08 Novozymes A/S Lipolytic enzyme
US6994963B1 (en) 2000-07-10 2006-02-07 Ambion, Inc. Methods for recombinatorial nucleic acid synthesis
US6858422B2 (en) 2000-07-13 2005-02-22 Codexis, Inc. Lipase genes
AUPQ974900A0 (en) * 2000-08-29 2000-09-21 Macquarie Research Limited Degenerate oligonucleotide gene-shuffling
US6582914B1 (en) 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
US6958213B2 (en) 2000-12-12 2005-10-25 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function
NZ528260A (en) 2001-05-18 2005-09-30 Danisco Method of improving dough and bread quality with the addition of an enzyme that hydrolyses a glycolipid and a phospholipid and incapable of hydrolysing a triglyceride or monoglyceride
ES2533923T3 (es) 2001-06-26 2015-04-16 Novozymes A/S Polipéptidos con actividad de celobiohidrolasa I y polinucleótidos que codifican los mismos
DK1409667T4 (da) 2001-07-23 2009-09-07 Dsm Ip Assets Bv Fremgangsm der til at fremstilling varierende polynucleotider
AU2003230027A1 (en) 2002-05-17 2003-12-02 Alligator Bioscience Ab A method for in vitro molecular evolution of protein function
EP1578964B2 (de) 2002-12-20 2013-09-04 Novozymes A/S Polypeptide mit cellobiohydrolase ii-aktivität und dafür kodierende polynucleotide
ES2534903T3 (es) 2002-12-20 2015-04-30 Novozymes A/S Variantes de galactanasas
MXPA05007653A (es) 2003-01-17 2005-09-30 Danisco Metodo.
DK2228440T3 (da) 2003-05-02 2013-01-02 Novozymes Inc Varianter af beta-glucosidaser
EP2617826B1 (de) 2003-08-25 2015-08-12 Novozymes Inc. Varianten von Glycosidhydrolasen
US7892808B2 (en) 2003-10-10 2011-02-22 Norozymes A/S Protease variants
WO2005080559A1 (en) 2004-02-25 2005-09-01 Novozymes A/S Fungall cell wall degrading enzyme
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
CA2565888C (en) 2004-05-27 2014-10-14 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a dna library
EP2267108A1 (de) 2004-07-16 2010-12-29 Danisco A/S Enzymatisches Ölentschleimungsverfahren
CN107667177A (zh) 2015-04-07 2018-02-06 诺维信公司 用于选择具有增强活性的酶的方法
US20180355404A1 (en) 2015-04-07 2018-12-13 Novozymes A/S Methods for selecting enzymes having lipase activity
EP3440207A1 (de) 2016-04-07 2019-02-13 Novozymes A/S Verfahren zur auswahl von enzymen mit proteaseaktivität

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination

Also Published As

Publication number Publication date
WO1998041623A1 (en) 1998-09-24
NZ337910A (en) 2001-10-26
EP1015575A1 (de) 2000-07-05
AU738461B2 (en) 2001-09-20
CA2284097A1 (en) 1998-09-24
DK1015575T3 (da) 2010-08-23
EP1015575B1 (de) 2010-05-19
JP2001516216A (ja) 2001-09-25
AU6611698A (en) 1998-10-12
DE69841674D1 (de) 2010-07-01
ATE468394T1 (de) 2010-06-15

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