IL130535A0 - Novel compounds with analgesic effect - Google Patents

Novel compounds with analgesic effect

Info

Publication number: IL130535A0
Authority: IL; Israel
Prior art keywords: novel compounds; analgesic effect; analgesic; effect; novel
Prior art date: 1996-12-20

Application number

IL13053597A

Other languages

English (en)

Original Assignee

Astra Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-20

Filing date

1997-12-09

Publication date

2000-06-01

1996-12-20 Priority claimed from SE9604785A external-priority patent/SE9604785D0/xx

1997-07-01 Priority claimed from SE9702535A external-priority patent/SE9702535D0/xx

1997-12-09 Application filed by Astra Pharma Inc filed Critical Astra Pharma Inc

2000-06-01 Publication of IL130535A0 publication Critical patent/IL130535A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL13053597A 1996-12-20 1997-12-09 Novel compounds with analgesic effect IL130535A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
SE9604785A SE9604785D0 (sv)	1996-12-20	1996-12-20	New compounds
SE9702535A SE9702535D0 (sv)	1997-07-01	1997-07-01	New compounds
PCT/SE1997/002050 WO1998028275A1 (en)	1996-12-20	1997-12-09	Novel compounds with analgesic effect

Publications (1)

Publication Number	Publication Date
IL130535A0 true IL130535A0 (en)	2000-06-01

Family

ID=26662830

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL13053597A IL130535A0 (en)	1996-12-20	1997-12-09	Novel compounds with analgesic effect
IL130535A IL130535A (en)	1996-12-20	1999-06-17	New compounds with an analgesic effect

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL130535A IL130535A (en)	1996-12-20	1999-06-17	New compounds with an analgesic effect

Country Status (28)

Country	Link
US (5)	US6187792B1 (et)
EP (1)	EP0946511B1 (et)
JP (1)	JP4324652B2 (et)
KR (1)	KR100549144B1 (et)
CN (2)	CN1146540C (et)
AR (1)	AR010376A1 (et)
AT (1)	ATE296288T1 (et)
AU (1)	AU737999B2 (et)
BR (1)	BR9714055B1 (et)
CA (1)	CA2274074C (et)
CZ (1)	CZ295557B6 (et)
DE (1)	DE69733362T2 (et)
EE (1)	EE03824B1 (et)
ES (1)	ES2241060T3 (et)
HU (1)	HU226724B1 (et)
ID (1)	ID22074A (et)
IL (2)	IL130535A0 (et)
IS (1)	IS2210B (et)
MY (1)	MY119403A (et)
NO (1)	NO313670B1 (et)
NZ (1)	NZ336029A (et)
PL (1)	PL189196B1 (et)
PT (1)	PT946511E (et)
RU (1)	RU2193029C2 (et)
SK (1)	SK283211B6 (et)
TR (1)	TR199901417T2 (et)
TW (1)	TW548271B (et)
WO (1)	WO1998028275A1 (et)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
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SE9504661D0 (sv)	1995-12-22	1995-12-22	Astra Pharma Inc	New compounds
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TW548271B (en) *	1996-12-20	2003-08-21	Astra Pharma Inc	Novel piperidine derivatives having an exocyclic double bond with analgesic effects
US6436959B1 (en)	1998-12-23	2002-08-20	Ortho-Mcneil Pharmaceutical, Inc.	4-[aryl(piperidin-4-yl)]aminobenzamides
US6635661B2 (en)	2000-05-25	2003-10-21	Sepracor Inc.	Heterocyclic analgesic compounds and methods of use thereof
WO2000071518A2 (en) *	1999-05-25	2000-11-30	Sepracor, Inc.	Heterocyclic analgesic compounds and their use
US6677332B1 (en)	1999-05-25	2004-01-13	Sepracor, Inc.	Heterocyclic analgesic compounds and methods of use thereof
US7361666B2 (en)	1999-05-25	2008-04-22	Sepracor, Inc.	Heterocyclic analgesic compounds and methods of use thereof
SE9904674D0 (sv)	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
SE9904673D0 (sv)	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
CA2395471A1 (en)	1999-12-22	2001-06-28	Ortho-Mcneil Pharmaceutical, Inc.	4-[aryl(8-azabicyclo[3.2.1]octan-3-yl)]aminobenzoic acid derivatives
AU2001232319B2 (en) *	2000-02-18	2005-01-13	Meiji Seika Kaisha, Ltd.	Phenoxyalkylamine derivates useful as opioid delta receptor ligands
US6552036B2 (en)	2000-03-03	2003-04-22	Ortho-Mcneil Pharmaceutical, Inc.	3-(Diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives
AU2001242744B2 (en)	2000-03-24	2005-07-21	Meiji Seika Kaisha Ltd	Diphenylalkylamine derivatives useful as opioid delta receptor ligands
SE0001209D0 (sv)	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
SE0001207D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
SE0001208D0 (sv) *	2000-04-04	2000-04-04	Astrazeneca Canada Inc	Novel compounds
AU2001216218A1 (en)	2000-05-25	2001-12-11	Sepracor, Inc.	Heterocyclic analgesic compounds and method of use thereof
WO2002048122A2 (en) *	2000-12-14	2002-06-20	Ortho-Mcneil Pharmaceutical, Inc.	Benzamidine derivatives
SE0101765D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101770D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101766D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101769D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101771D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101768D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101773D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101767D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
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SE0103313D0 (sv) *	2001-10-03	2001-10-03	Astrazeneca Ab	Novel compounds
ATE347549T1 (de)	2001-10-15	2006-12-15	Janssen Pharmaceutica Nv	Neue substituierte 4-phenyl-4-(1h-imidazo-2-yl)- piperidin-derivate und ihre anwendung als selective delta-opioid-agonisten
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SE0301441D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301443D0 (sv) *	2003-05-16	2003-05-16	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
RU2005136524A (ru) *	2003-05-16	2006-06-27	Астразенека Аб (Se)	Производные диарилметилиденпиперидина, способы их получения и их применение
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SE0400026D0 (sv) *	2004-01-09	2004-01-09	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0400025D0 (sv) *	2004-01-09	2004-01-09	Astrazeneca Ab	Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
WO2005075472A1 (en) *	2004-02-03	2005-08-18	Janssen Pharmaceutica, N.V.	3-(diheteroarylnethylene)-8-azabicyclo[3.2.1]octane and 3-(aryl)(heteroaryl)methylene)-8-azabicyclo[3.2.1]octane derivatives
HRP20120343T1 (hr)	2004-08-02	2012-05-31	Astrazeneca Ab	Derivati diarilmetil piperazina, njihovi pripravci i njihova uporaba
CA2574768A1 (en)	2004-08-05	2006-02-05	Janssen Pharmaceutica N.V.	Tricyclic delta-opioid modulators
SE0402485D0 (sv) *	2004-10-13	2004-10-13	Astrazeneca Ab	Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt
AU2005319060A1 (en)	2004-12-22	2006-06-29	Janssen Pharmaceutica N.V.	Tricyclic delta-opioid modulators
CA2592464A1 (en) *	2004-12-22	2006-06-29	Janssen Pharmaceutica N.V.	Tricyclic .delta.-opioid modulators
CA2594347A1 (en)	2005-01-06	2006-07-13	Janssen Pharmaceutica N.V.	Tricyclic d-opioid modulators
US7557875B2 (en)	2005-03-22	2009-07-07	Industrial Technology Research Institute	High performance flexible display with improved mechanical properties having electrically modulated material mixed with binder material in a ratio between 6:1 and 0.5:1
AU2006236622B2 (en) *	2005-04-14	2011-09-22	Versi Group Llc	Compositions of novel opioid compounds and method of use thereof
CN101243079A (zh)	2005-06-16	2008-08-13	詹森药业有限公司	三环阿片调节剂
US7576207B2 (en)	2006-04-06	2009-08-18	Adolor Corporation	Spirocyclic heterocyclic derivatives and methods of their use
AU2007292346B2 (en) *	2006-09-06	2014-02-06	Smith & Nephew, Inc.	Implants with transition surfaces and related processes
MY148880A (en)	2006-10-20	2013-06-14	Astrazeneca Ab	N-(2-hydroxyethyl)-n-methyl-4-(quinolin-8-yl(1-(thiazol-4-ylmethyl)piperidin-4-ylidene)methyl)benzamide, the process of making it as well as its use for the treatment of pain, anxiety and depression
CN101910097B (zh) *	2007-12-06	2013-09-18	国际壳牌研究有限公司	制备亚烷基二醇的方法和反应器
SMT202000371T1 (it) *	2014-12-19	2020-09-10	Pharmnovo Ab	Derivati della piperidina diarilmetilidene e loro uso come agonisti dei recettori degli oppioidi delta
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1997
- 1997-12-08 TW TW086118465A patent/TW548271B/zh not_active IP Right Cessation
- 1997-12-09 SK SK762-99A patent/SK283211B6/sk not_active IP Right Cessation
- 1997-12-09 WO PCT/SE1997/002050 patent/WO1998028275A1/en not_active Ceased
- 1997-12-09 AU AU53512/98A patent/AU737999B2/en not_active Ceased
- 1997-12-09 US US09/029,633 patent/US6187792B1/en not_active Expired - Lifetime
- 1997-12-09 CN CNB971818142A patent/CN1146540C/zh not_active Expired - Fee Related
- 1997-12-09 CA CA002274074A patent/CA2274074C/en not_active Expired - Fee Related
- 1997-12-09 DE DE69733362T patent/DE69733362T2/de not_active Expired - Lifetime
- 1997-12-09 RU RU99115750/04A patent/RU2193029C2/ru not_active IP Right Cessation
- 1997-12-09 EP EP97950538A patent/EP0946511B1/en not_active Expired - Lifetime
- 1997-12-09 AT AT97950538T patent/ATE296288T1/de not_active IP Right Cessation
- 1997-12-09 CZ CZ19992199A patent/CZ295557B6/cs not_active IP Right Cessation
- 1997-12-09 NZ NZ336029A patent/NZ336029A/en unknown
- 1997-12-09 ES ES97950538T patent/ES2241060T3/es not_active Expired - Lifetime
- 1997-12-09 TR TR1999/01417T patent/TR199901417T2/xx unknown
- 1997-12-09 JP JP52866998A patent/JP4324652B2/ja not_active Expired - Fee Related
- 1997-12-09 IL IL13053597A patent/IL130535A0/xx active IP Right Grant
- 1997-12-09 BR BRPI9714055-4A patent/BR9714055B1/pt not_active IP Right Cessation
- 1997-12-09 CN CNB2004100082366A patent/CN100519528C/zh not_active Expired - Fee Related
- 1997-12-09 KR KR1019997005585A patent/KR100549144B1/ko not_active Expired - Fee Related
- 1997-12-09 HU HU0000610A patent/HU226724B1/hu not_active IP Right Cessation
- 1997-12-09 PT PT97950538T patent/PT946511E/pt unknown
- 1997-12-09 PL PL97334374A patent/PL189196B1/pl not_active IP Right Cessation
- 1997-12-09 ID IDW990508A patent/ID22074A/id unknown
- 1997-12-09 EE EEP199900256A patent/EE03824B1/et not_active IP Right Cessation
- 1997-12-19 AR ARP970106074A patent/AR010376A1/es active IP Right Grant
- 1997-12-19 MY MYPI97006173A patent/MY119403A/en unknown
1999
- 1999-06-07 IS IS5071A patent/IS2210B/is unknown
- 1999-06-17 IL IL130535A patent/IL130535A/en not_active IP Right Cessation
- 1999-06-18 NO NO19993022A patent/NO313670B1/no not_active IP Right Cessation
2001
- 2001-01-18 US US09/761,833 patent/US6455545B2/en not_active Expired - Fee Related
2002
- 2002-08-19 US US10/222,990 patent/US6693117B2/en not_active Expired - Fee Related
2003
- 2003-12-09 US US10/730,265 patent/US7312336B2/en not_active Expired - Fee Related
2007
- 2007-12-05 US US11/951,014 patent/US20080176903A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US6693117B2 (en)	2004-02-17
CA2274074C (en)	2006-07-11
SK283211B6 (sk)	2003-03-04
IL130535A (en)	2006-04-10
DE69733362T2 (de)	2006-02-02
BR9714055A (pt)	2000-05-09
CZ219999A3 (cs)	1999-11-17
ES2241060T3 (es)	2005-10-16
DE69733362D1 (de)	2005-06-30
HK1022689A1 (en)	2000-08-18
RU2193029C2 (ru)	2002-11-20
TR199901417T2 (xx)	1999-10-21
ID22074A (id)	1999-09-02
MY119403A (en)	2005-05-31
ATE296288T1 (de)	2005-06-15
CN100519528C (zh)	2009-07-29
CN1246111A (zh)	2000-03-01
KR100549144B1 (ko)	2006-02-03
US6455545B2 (en)	2002-09-24
US6187792B1 (en)	2001-02-13
US20010021715A1 (en)	2001-09-13
NO993022D0 (no)	1999-06-18
EP0946511A1 (en)	1999-10-06
EE03824B1 (et)	2002-08-15
US20030149023A1 (en)	2003-08-07
JP4324652B2 (ja)	2009-09-02
HU226724B1 (en)	2009-08-28
US20080176903A1 (en)	2008-07-24
CN1146540C (zh)	2004-04-21
EP0946511B1 (en)	2005-05-25
NO313670B1 (no)	2002-11-11
PL334374A1 (en)	2000-02-28
NO993022L (no)	1999-08-20
KR20000069599A (ko)	2000-11-25
AU737999B2 (en)	2001-09-06
US7312336B2 (en)	2007-12-25
IS5071A (is)	1999-06-07
CN1524852A (zh)	2004-09-01
CA2274074A1 (en)	1998-07-02
CZ295557B6 (cs)	2005-08-17
SK76299A3 (en)	1999-11-08
BR9714055B1 (pt)	2010-02-23
PL189196B1 (pl)	2005-07-29
WO1998028275A1 (en)	1998-07-02
NZ336029A (en)	2001-03-30
US20040171612A1 (en)	2004-09-02
IS2210B (is)	2007-02-15
JP2001507350A (ja)	2001-06-05
AU5351298A (en)	1998-07-17
PT946511E (pt)	2005-09-30
HUP0000610A2 (hu)	2000-09-28
EE9900256A (et)	1999-12-15
TW548271B (en)	2003-08-21
AR010376A1 (es)	2000-06-07
HUP0000610A3 (en)	2000-10-30

Publication	Publication Date	Title
IL130535A0 (en)	2000-06-01	Novel compounds with analgesic effect
IL130536A0 (en)	2000-06-01	Novel compounds with analgesic effect
EG25688A (en)	2012-05-20	Novel compounds with analgesic effect
PL324170A1 (en)	1998-05-11	Novel pharmaceutic composition having analgesic effect
EP0914330A4 (en)	2002-01-09	NEW TYPE COMPOUNDS
EP0961618A4 (en)	2002-07-17	NEW COMPOUNDS
EP0909181A4 (en)	1999-11-03	NEW COMPOUNDS
GB9601067D0 (en)	1996-03-20	Novel compounds
EP0904105A4 (en)	1999-10-20	NEW COMPOUNDS
PT799819E (pt)	2003-01-31	Compostos de 1-dimetilaminometil-2-fenilcicloalc-2-eno com efeito analgesico
HUP0003636A3 (en)	2001-12-28	Analgesic combination
AP9701047A0 (en)	1997-07-31	Novel compounds
ZA9610355B (en)	1997-06-23	Novel compounds with analgesic effect
GB9600955D0 (en)	1996-03-20	Novel compounds
GB9604045D0 (en)	1996-04-24	Novel compounds
GB9601041D0 (en)	1996-03-20	Novel compounds
AP9701037A0 (en)	1997-07-31	Novel compounds
GB9601069D0 (en)	1996-03-20	Novel compounds
EP0954525A4 (en)	2001-09-12	NEW CONNECTIONS
SI0946510T1 (en)	2004-12-31	Novel compounds with analgesic effect
SI0946511T1 (en)	2005-10-31	Novel compounds with analgesic effect
ZA9711059B (en)	1998-06-22	Novel compounds with analgesic effect.
GB9601068D0 (en)	1996-03-20	Novel compounds
EP0907377A4 (en)	2001-11-21	NEW CONNECTIONS
GB9601066D0 (en)	1996-03-20	Novel compounds

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2006-09-05	FF	Patent granted
2006-10-04	KB	Patent renewed
2008-01-06	KB	Patent renewed