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IL139865A0 - A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same - Google Patents

A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same

Info

Publication number
IL139865A0
IL139865A0 IL13986599A IL13986599A IL139865A0 IL 139865 A0 IL139865 A0 IL 139865A0 IL 13986599 A IL13986599 A IL 13986599A IL 13986599 A IL13986599 A IL 13986599A IL 139865 A0 IL139865 A0 IL 139865A0
Authority
IL
Israel
Prior art keywords
same
pharmaceutical compositions
compositions containing
selective glucocorticoid
glucocorticoid antagonist
Prior art date
Application number
IL13986599A
Original Assignee
Karobio Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9812314.4A external-priority patent/GB9812314D0/en
Priority claimed from GBGB9815149.1A external-priority patent/GB9815149D0/en
Application filed by Karobio Ab filed Critical Karobio Ab
Publication of IL139865A0 publication Critical patent/IL139865A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13986599A 1998-06-08 1999-06-07 A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same IL139865A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9812314.4A GB9812314D0 (en) 1998-06-08 1998-06-08 Treatment of diabetes
GBGB9815149.1A GB9815149D0 (en) 1998-07-13 1998-07-13 Treatment of diabetes
PCT/IB1999/001175 WO1999063976A2 (en) 1998-06-08 1999-06-07 Liver-selective glucocorticoid antagonist for treating diabetes

Publications (1)

Publication Number Publication Date
IL139865A0 true IL139865A0 (en) 2002-02-10

Family

ID=26313822

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13986599A IL139865A0 (en) 1998-06-08 1999-06-07 A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same

Country Status (7)

Country Link
EP (1) EP1143948A3 (en)
JP (1) JP2002527355A (en)
KR (1) KR20010052431A (en)
AU (1) AU751569B2 (en)
CA (1) CA2334116A1 (en)
IL (1) IL139865A0 (en)
WO (1) WO1999063976A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9816935D0 (en) * 1998-08-05 1998-09-30 Karobio Ab Novel glucocortoid and thyroid receptor ligands for the treatment of metabolic disorders
GB9907048D0 (en) * 1999-03-27 1999-05-19 Karobio Ab Novel glucocorticoid receptor ligands for the treatment of meta bolic disorders
GB9928805D0 (en) * 1999-12-07 2000-02-02 Karobio Ab Compounds active at the Glucocorticoid and Thyroid Hormone Receptors
EP1201660B1 (en) 2000-10-30 2005-08-31 Pfizer Products Inc. Glucocorticoid receptor modulators
GB0029102D0 (en) * 2000-11-29 2001-01-10 Karobio Ab Compounds active at the glucocorticoid receptor
GB0029100D0 (en) * 2000-11-29 2001-01-10 Karobio Ab Compounds active at the glucocorticoid receptor
MXPA03005328A (en) * 2000-12-20 2004-12-03 Boehringer Ingelheim Pharma Dissociated glucocorticoid receptor antagonists for the treatment of clucocorticoid associated side-effect.
MXPA03007261A (en) * 2001-02-14 2006-03-09 Abbott Lab Glucocorticoid receptor modulators.
US6583180B2 (en) 2001-02-14 2003-06-24 Abbott Laboratories Glucocorticoid receptor modulators
EP1285927A3 (en) 2001-08-16 2005-06-29 Schering Aktiengesellschaft Use of glucocorticoid antagonists for the prevention and treatment of diseases of the male reproductive system
WO2003059253A2 (en) * 2001-12-21 2003-07-24 Smithkline Beecham Corporation Compositions and methods for altering glucose production
KR101022977B1 (en) 2002-03-26 2011-03-18 베링거 인겔하임 파마슈티칼즈, 인코포레이티드 Glucocorticoid mimetics, preparation methods thereof, pharmaceutical compositions and uses thereof
US7186864B2 (en) 2002-05-29 2007-03-06 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7074806B2 (en) 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US8097606B2 (en) 2003-07-23 2012-01-17 Corcept Therapeutics, Inc. Antiglucocorticoids for the treatment of catatonia
US7527829B2 (en) 2003-07-31 2009-05-05 Soken Chemical & Engineering Co., Ltd. Fluid colloid crystal and process for producing three-dimensional aligned particle mass therefrom
UY28526A1 (en) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma GLUCOCORTICOID MIMETICS, METHODS OF PREPARATION PHARMACEUTICAL COMPOSITIONS AND USES OF THE SAME
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
US7741361B2 (en) 2004-12-27 2010-06-22 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
JP2010512331A (en) 2006-12-06 2010-04-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Glucocorticoid mimetics, methods for their production, pharmaceutical compositions, and uses thereof
ATE541846T1 (en) 2008-06-06 2012-02-15 Boehringer Ingelheim Int GLUCOCORTICOID MIMETICS, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITIONS AND APPLICATIONS THEREOF
US8138189B2 (en) * 2009-03-26 2012-03-20 Hoffman-La Roche Inc. Substituted benzene compounds as modulators of the glucocorticoid receptor
JP2013500962A (en) 2009-07-31 2013-01-10 カディラ ヘルスケア リミティド Novel compounds as modulators of glucocorticoid receptors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374148A (en) * 1980-10-21 1983-02-15 Pfizer Inc. Carboxylic acid therapeutic agents
AU5729098A (en) * 1996-12-24 1998-07-17 Zymogenetics Inc. Treatment agents and methods for treating type ii diabetes and symptoms of type ii diabetes

Also Published As

Publication number Publication date
WO1999063976A3 (en) 2001-12-20
EP1143948A2 (en) 2001-10-17
KR20010052431A (en) 2001-06-25
CA2334116A1 (en) 1999-12-16
WO1999063976A2 (en) 1999-12-16
AU751569B2 (en) 2002-08-22
AU4160699A (en) 1999-12-30
JP2002527355A (en) 2002-08-27
EP1143948A3 (en) 2002-09-11

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