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IL138747A0 - G-protein fusion receptors and chimeric gabab receptors - Google Patents

G-protein fusion receptors and chimeric gabab receptors

Info

Publication number
IL138747A0
IL138747A0 IL13874799A IL13874799A IL138747A0 IL 138747 A0 IL138747 A0 IL 138747A0 IL 13874799 A IL13874799 A IL 13874799A IL 13874799 A IL13874799 A IL 13874799A IL 138747 A0 IL138747 A0 IL 138747A0
Authority
IL
Israel
Prior art keywords
receptors
protein fusion
chimeric
gabab
chimeric gabab
Prior art date
Application number
IL13874799A
Original Assignee
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Pharma Inc filed Critical Nps Pharma Inc
Publication of IL138747A0 publication Critical patent/IL138747A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4722—G-proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13874799A 1998-04-03 1999-04-02 G-protein fusion receptors and chimeric gabab receptors IL138747A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8067198P 1998-04-03 1998-04-03
PCT/US1999/007333 WO1999051641A1 (en) 1998-04-03 1999-04-02 G-protein fusion receptors and chimeric gabab receptors

Publications (1)

Publication Number Publication Date
IL138747A0 true IL138747A0 (en) 2001-10-31

Family

ID=22158879

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13874799A IL138747A0 (en) 1998-04-03 1999-04-02 G-protein fusion receptors and chimeric gabab receptors

Country Status (6)

Country Link
EP (1) EP1066325A1 (en)
JP (1) JP2002510480A (en)
AU (1) AU768422B2 (en)
CA (1) CA2325334A1 (en)
IL (1) IL138747A0 (en)
WO (1) WO1999051641A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7262280B1 (en) 1998-04-03 2007-08-28 Nps Pharmaceuticals, Inc. G-protein fusion receptors and constructs encoding same
ATE343634T1 (en) * 1998-09-07 2006-11-15 Glaxo Group Ltd GABA B RECEPTOR SUBTYPES GABA B-R1C AND GABA B-R2 AND THEIR HETERODIMERS
EP1112363A1 (en) * 1998-09-14 2001-07-04 BASF-LYNX Bioscience AG Metabotropic gaba receptor complex issued from the central nervous system
US6534287B1 (en) * 1999-10-25 2003-03-18 Nps Pharmaceuticals, Inc. Human metabotropic glutamate receptor
AU2002213016A1 (en) * 2000-10-03 2002-04-15 Nps Pharmaceuticals, Inc. G-protein fusion receptors and chimeric gabab receptors
CN104277106B (en) * 2013-07-03 2018-04-20 深圳大学 Mammalian cell directional guide method based on g protein coupled receptor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69132546T2 (en) * 1990-09-13 2001-10-04 Duke University, Durham EXPRESSION OF RECEPTORS COUPLED TO G-PROTEIN IN YEAST
CA2200606A1 (en) * 1995-07-26 1997-02-13 Nps Pharmaceuticals, Inc. Chimeric receptors and methods for identifying compounds active at metabotropic glutamate receptors and the use of such compounds in the treatment of neurological disorders and diseases
US6084084A (en) * 1996-02-21 2000-07-04 Nps Pharmaceuticals, Inc. Human metabotropic glutamate receptor
CA2254862A1 (en) * 1996-05-30 1997-12-11 Novartis Ag Metabotropic gaba[b] receptors, receptor-specific ligands and their uses
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
US6221609B1 (en) * 1996-07-03 2001-04-24 Eli Lilly And Company Isolate nucleic acid encoding human MGLUR8
WO1999020751A1 (en) * 1997-10-17 1999-04-29 Synaptic Pharmaceutical Corporation Dna encoding a gababr2 polypeptide and uses thereof

Also Published As

Publication number Publication date
CA2325334A1 (en) 1999-10-14
JP2002510480A (en) 2002-04-09
WO1999051641A1 (en) 1999-10-14
EP1066325A1 (en) 2001-01-10
AU768422B2 (en) 2003-12-11
AU3380199A (en) 1999-10-25

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