IL137608A0 - Use of 2-amino-6- trifluoromethoxy-benzothiazole for preventing or treating cerebellum dysfunction - Google Patents
Use of 2-amino-6- trifluoromethoxy-benzothiazole for preventing or treating cerebellum dysfunctionInfo
- Publication number
- IL137608A0 IL137608A0 IL13760899A IL13760899A IL137608A0 IL 137608 A0 IL137608 A0 IL 137608A0 IL 13760899 A IL13760899 A IL 13760899A IL 13760899 A IL13760899 A IL 13760899A IL 137608 A0 IL137608 A0 IL 137608A0
- Authority
- IL
- Israel
- Prior art keywords
- benzothiazole
- trifluoromethoxy
- amino
- treating
- preventing
- Prior art date
Links
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 2
- 210000001638 cerebellum Anatomy 0.000 title 1
- 230000004064 dysfunction Effects 0.000 title 1
- 206010008025 Cerebellar ataxia Diseases 0.000 abstract 1
- 208000015879 Cerebellar disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960004181 riluzole Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9801402A FR2774592B1 (fr) | 1998-02-06 | 1998-02-06 | Application du 2-amino-6-trifluoromethoxybenzothiazole pour la prevention ou le traitement des dysfonctionnements du cervelet |
| PCT/FR1999/000230 WO1999039710A1 (fr) | 1998-02-06 | 1999-02-03 | Application du 2-amino-6- trifluoromethoxy- benzothiazole pour la prevention ou le traitement des dysfonctionnements du cervelet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137608A0 true IL137608A0 (en) | 2001-07-24 |
Family
ID=9522673
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13760899A IL137608A0 (en) | 1998-02-06 | 1999-02-03 | Use of 2-amino-6- trifluoromethoxy-benzothiazole for preventing or treating cerebellum dysfunction |
| IL137608A IL137608A (en) | 1998-02-06 | 2000-07-31 | Use of 2-amino-6-trifluoromethoxy-benzothiazole in the preparation of drugs for the prevention or treatment of dysfunction of the serum |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL137608A IL137608A (en) | 1998-02-06 | 2000-07-31 | Use of 2-amino-6-trifluoromethoxy-benzothiazole in the preparation of drugs for the prevention or treatment of dysfunction of the serum |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6245791B1 (xx) |
| EP (1) | EP1052989B1 (xx) |
| JP (1) | JP5127092B2 (xx) |
| KR (1) | KR100574378B1 (xx) |
| AT (1) | ATE245982T1 (xx) |
| AU (1) | AU761978B2 (xx) |
| CA (1) | CA2319686C (xx) |
| DE (1) | DE69909970T2 (xx) |
| DK (1) | DK1052989T3 (xx) |
| EA (1) | EA002676B1 (xx) |
| ES (1) | ES2199541T3 (xx) |
| FR (1) | FR2774592B1 (xx) |
| IL (2) | IL137608A0 (xx) |
| NO (1) | NO327819B1 (xx) |
| NZ (1) | NZ506124A (xx) |
| PT (1) | PT1052989E (xx) |
| WO (1) | WO1999039710A1 (xx) |
| ZA (1) | ZA99740B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60041365D1 (de) * | 1999-06-04 | 2009-02-26 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Verwendung von Riluzol zur Behandlung Multipler Sklerose |
| AU2016226463B2 (en) * | 2015-03-03 | 2020-06-25 | Biohaven Pharmaceutical Holding Company Ltd. | Riluzole prodrugs and their use |
| FI3706739T3 (fi) * | 2017-11-12 | 2024-12-27 | Biohaven Therapeutics Ltd | Rilutsoliaihiolääkkeiden käyttö ataksioiden hoitamiseksi |
| US12364687B2 (en) * | 2018-05-27 | 2025-07-22 | Biohaven Therapeutics Ltd. | Use of riluzole oral disintegrating tablets for treating diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68901859T2 (de) * | 1988-12-15 | 1993-01-14 | Rhone Poulenc Sante | 2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung. |
| FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
| FR2702148B1 (fr) * | 1993-03-05 | 1995-04-07 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement du neuro-sida. |
| FR2714828B1 (fr) * | 1994-01-12 | 1996-02-02 | Rhone Poulenc Rorer Sa | Application du riluzole dans le traitement des maladies mitochondriales. |
| FR2726271B1 (fr) * | 1994-10-26 | 1996-12-06 | Rhone Poulenc Rorer Sa | Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole |
-
1998
- 1998-02-06 FR FR9801402A patent/FR2774592B1/fr not_active Expired - Fee Related
-
1999
- 1999-01-29 ZA ZA9900740A patent/ZA99740B/xx unknown
- 1999-02-03 ES ES99901703T patent/ES2199541T3/es not_active Expired - Lifetime
- 1999-02-03 EA EA200000816A patent/EA002676B1/ru not_active IP Right Cessation
- 1999-02-03 DE DE69909970T patent/DE69909970T2/de not_active Expired - Lifetime
- 1999-02-03 CA CA002319686A patent/CA2319686C/fr not_active Expired - Lifetime
- 1999-02-03 WO PCT/FR1999/000230 patent/WO1999039710A1/fr not_active Ceased
- 1999-02-03 AT AT99901703T patent/ATE245982T1/de active
- 1999-02-03 JP JP2000530209A patent/JP5127092B2/ja not_active Expired - Lifetime
- 1999-02-03 EP EP99901703A patent/EP1052989B1/fr not_active Expired - Lifetime
- 1999-02-03 KR KR1020007008545A patent/KR100574378B1/ko not_active Expired - Fee Related
- 1999-02-03 DK DK99901703T patent/DK1052989T3/da active
- 1999-02-03 NZ NZ506124A patent/NZ506124A/en not_active IP Right Cessation
- 1999-02-03 PT PT99901703T patent/PT1052989E/pt unknown
- 1999-02-03 AU AU21711/99A patent/AU761978B2/en not_active Expired
- 1999-02-03 IL IL13760899A patent/IL137608A0/xx active IP Right Grant
-
2000
- 2000-07-24 NO NO20003785A patent/NO327819B1/no not_active IP Right Cessation
- 2000-07-31 IL IL137608A patent/IL137608A/en not_active IP Right Cessation
- 2000-08-03 US US09/631,798 patent/US6245791B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU761978B2 (en) | 2003-06-12 |
| CA2319686C (fr) | 2009-06-23 |
| ES2199541T3 (es) | 2004-02-16 |
| IL137608A (en) | 2006-09-05 |
| EP1052989A1 (fr) | 2000-11-22 |
| AU2171199A (en) | 1999-08-23 |
| KR20010040671A (ko) | 2001-05-15 |
| ATE245982T1 (de) | 2003-08-15 |
| CA2319686A1 (fr) | 1999-08-12 |
| DK1052989T3 (da) | 2003-11-17 |
| FR2774592B1 (fr) | 2000-03-17 |
| PT1052989E (pt) | 2003-12-31 |
| NO20003785D0 (no) | 2000-07-24 |
| FR2774592A1 (fr) | 1999-08-13 |
| US6245791B1 (en) | 2001-06-12 |
| NO20003785L (no) | 2000-07-24 |
| ZA99740B (en) | 1999-08-02 |
| NO327819B1 (no) | 2009-09-28 |
| EA200000816A1 (ru) | 2001-02-26 |
| NZ506124A (en) | 2003-07-25 |
| JP2002502819A (ja) | 2002-01-29 |
| KR100574378B1 (ko) | 2006-04-26 |
| WO1999039710A1 (fr) | 1999-08-12 |
| DE69909970D1 (de) | 2003-09-04 |
| DE69909970T2 (de) | 2004-05-27 |
| EA002676B1 (ru) | 2002-08-29 |
| JP5127092B2 (ja) | 2013-01-23 |
| EP1052989B1 (fr) | 2003-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |