IL136659A - New antiarrhythmic compounds and pharmaceuticals containing them - Google Patents
New antiarrhythmic compounds and pharmaceuticals containing themInfo
- Publication number
- IL136659A IL136659A IL13665998A IL13665998A IL136659A IL 136659 A IL136659 A IL 136659A IL 13665998 A IL13665998 A IL 13665998A IL 13665998 A IL13665998 A IL 13665998A IL 136659 A IL136659 A IL 136659A
- Authority
- IL
- Israel
- Prior art keywords
- ethyl
- compounds
- methyl
- dimethylphenoxy
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/20—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9702411A HUP9702411A2 (hu) | 1997-12-11 | 1997-12-11 | Fenoxi-alkil-amin-származékok és a vegyületeket tartalmazó antiaritmiás hatású gyógyszerkészítmények |
| PCT/HU1998/000101 WO1999029655A1 (en) | 1997-12-11 | 1998-12-10 | Novel antiarrhythmic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL136659A0 IL136659A0 (en) | 2001-06-14 |
| IL136659A true IL136659A (en) | 2004-08-31 |
Family
ID=89995855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13665998A IL136659A (en) | 1997-12-11 | 1998-12-10 | New antiarrhythmic compounds and pharmaceuticals containing them |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6265445B1 (pt) |
| EP (1) | EP1037871B1 (pt) |
| JP (1) | JP2001525388A (pt) |
| KR (1) | KR100576905B1 (pt) |
| CN (1) | CN1140498C (pt) |
| AT (1) | ATE220058T1 (pt) |
| AU (1) | AU738672B2 (pt) |
| BR (1) | BR9814270A (pt) |
| CA (1) | CA2313191A1 (pt) |
| DE (1) | DE69806411T2 (pt) |
| DK (1) | DK1037871T3 (pt) |
| ES (1) | ES2179547T3 (pt) |
| HU (1) | HUP9702411A2 (pt) |
| IL (1) | IL136659A (pt) |
| NO (1) | NO20002946L (pt) |
| NZ (1) | NZ504982A (pt) |
| PL (1) | PL190788B1 (pt) |
| PT (1) | PT1037871E (pt) |
| RU (1) | RU2193024C2 (pt) |
| SK (1) | SK284284B6 (pt) |
| UA (1) | UA61979C2 (pt) |
| WO (1) | WO1999029655A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19956786A1 (de) * | 1999-11-25 | 2001-05-31 | Basf Ag | Verfahren zur Herstellung optisch aktiver Amine |
| US20030119406A1 (en) | 2001-12-20 | 2003-06-26 | Abuto Francis Paul | Targeted on-line stabilized absorbent structures |
| WO2003091205A1 (fr) * | 2002-04-26 | 2003-11-06 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Sulfamidophenylalkylamines, production et utilisation de ces dernieres |
| CN102603543B (zh) * | 2012-04-09 | 2014-07-02 | 佛山普正医药科技有限公司 | 一种盐酸美西律的生产方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD146749A3 (de) * | 1977-12-01 | 1981-03-04 | Dieter Lehmann | Verfahren zur herstellung von phenoxyalkanolamin-derivaten |
| EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
| NO179246C (no) * | 1991-11-20 | 1996-09-04 | Sankyo Co | Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav |
| JPH06107614A (ja) * | 1992-09-26 | 1994-04-19 | Arakusu:Kk | アリールスルホン酸アミド類またはアリールカルボン酸アミド類及びそれらの薬剤として許容される酸付加塩及びその製造法並びにそれを有効成分とする抗消化性潰瘍剤 |
-
1997
- 1997-12-11 HU HU9702411A patent/HUP9702411A2/hu unknown
-
1998
- 1998-10-12 UA UA2000063362A patent/UA61979C2/uk unknown
- 1998-12-10 SK SK879-2000A patent/SK284284B6/sk not_active IP Right Cessation
- 1998-12-10 AT AT98961331T patent/ATE220058T1/de not_active IP Right Cessation
- 1998-12-10 NZ NZ504982A patent/NZ504982A/en unknown
- 1998-12-10 JP JP2000524252A patent/JP2001525388A/ja active Pending
- 1998-12-10 IL IL13665998A patent/IL136659A/en not_active IP Right Cessation
- 1998-12-10 WO PCT/HU1998/000101 patent/WO1999029655A1/en not_active Ceased
- 1998-12-10 DE DE69806411T patent/DE69806411T2/de not_active Expired - Lifetime
- 1998-12-10 RU RU2000118325/04A patent/RU2193024C2/ru not_active IP Right Cessation
- 1998-12-10 CA CA002313191A patent/CA2313191A1/en not_active Abandoned
- 1998-12-10 DK DK98961331T patent/DK1037871T3/da active
- 1998-12-10 BR BR9814270-4A patent/BR9814270A/pt not_active Application Discontinuation
- 1998-12-10 KR KR1020007006348A patent/KR100576905B1/ko not_active Expired - Fee Related
- 1998-12-10 US US09/555,602 patent/US6265445B1/en not_active Expired - Fee Related
- 1998-12-10 ES ES98961331T patent/ES2179547T3/es not_active Expired - Lifetime
- 1998-12-10 AU AU16789/99A patent/AU738672B2/en not_active Ceased
- 1998-12-10 EP EP98961331A patent/EP1037871B1/en not_active Expired - Lifetime
- 1998-12-10 PL PL341107A patent/PL190788B1/pl not_active IP Right Cessation
- 1998-12-10 PT PT98961331T patent/PT1037871E/pt unknown
- 1998-12-10 CN CNB988135779A patent/CN1140498C/zh not_active Expired - Fee Related
-
2000
- 2000-06-08 NO NO20002946A patent/NO20002946L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1284941A (zh) | 2001-02-21 |
| NO20002946L (no) | 2000-08-07 |
| PL190788B1 (pl) | 2006-01-31 |
| AU738672B2 (en) | 2001-09-20 |
| KR20010032996A (ko) | 2001-04-25 |
| DE69806411D1 (de) | 2002-08-08 |
| IL136659A0 (en) | 2001-06-14 |
| EP1037871B1 (en) | 2002-07-03 |
| AU1678999A (en) | 1999-06-28 |
| UA61979C2 (en) | 2003-12-15 |
| EP1037871A1 (en) | 2000-09-27 |
| WO1999029655A1 (en) | 1999-06-17 |
| RU2193024C2 (ru) | 2002-11-20 |
| CA2313191A1 (en) | 1999-06-17 |
| BR9814270A (pt) | 2001-10-16 |
| HK1033937A1 (en) | 2001-10-05 |
| HUP9702411A2 (hu) | 2000-03-28 |
| HU9702411D0 (en) | 1998-03-02 |
| JP2001525388A (ja) | 2001-12-11 |
| US6265445B1 (en) | 2001-07-24 |
| NZ504982A (en) | 2002-07-26 |
| KR100576905B1 (ko) | 2006-05-03 |
| PT1037871E (pt) | 2002-11-29 |
| SK284284B6 (sk) | 2005-01-03 |
| CN1140498C (zh) | 2004-03-03 |
| SK8792000A3 (en) | 2001-02-12 |
| PL341107A1 (en) | 2001-03-26 |
| NO20002946D0 (no) | 2000-06-08 |
| ATE220058T1 (de) | 2002-07-15 |
| DE69806411T2 (de) | 2003-03-20 |
| ES2179547T3 (es) | 2003-01-16 |
| DK1037871T3 (da) | 2002-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |