IL134437A0 - Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same - Google Patents
Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing sameInfo
- Publication number
- IL134437A0 IL134437A0 IL13443798A IL13443798A IL134437A0 IL 134437 A0 IL134437 A0 IL 134437A0 IL 13443798 A IL13443798 A IL 13443798A IL 13443798 A IL13443798 A IL 13443798A IL 134437 A0 IL134437 A0 IL 134437A0
- Authority
- IL
- Israel
- Prior art keywords
- optically pure
- preparing same
- synthesis intermediate
- camptothecin analogues
- analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9710785A FR2768431B1 (en) | 1997-08-29 | 1997-08-29 | NOVEL OPTICALLY PURE CAMPTOTHECIN ANALOGS, A NEW OPTICALLY PURE SYNTHESIS INTERMEDIATE AND PROCESS FOR PREPARING THE SAME |
| PCT/FR1998/001768 WO1999011646A1 (en) | 1997-08-29 | 1998-08-07 | Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL134437A0 true IL134437A0 (en) | 2001-04-30 |
Family
ID=9510590
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13443798A IL134437A0 (en) | 1997-08-29 | 1998-08-07 | Optically pure camptothecin analogues, optically pure synthesis intermediate and method for preparing same |
| IL134437A IL134437A (en) | 1997-08-29 | 2000-02-08 | Optically pure homocamptothecin derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL134437A IL134437A (en) | 1997-08-29 | 2000-02-08 | Optically pure homocamptothecin derivatives |
Country Status (25)
| Country | Link |
|---|---|
| EP (2) | EP1378512A1 (en) |
| JP (1) | JP2001514261A (en) |
| KR (1) | KR100570254B1 (en) |
| CN (3) | CN1104434C (en) |
| AR (1) | AR016856A1 (en) |
| AT (1) | ATE253069T1 (en) |
| AU (1) | AU760863B2 (en) |
| BR (1) | BR9811405A (en) |
| CA (1) | CA2301739C (en) |
| CZ (1) | CZ297896B6 (en) |
| DE (1) | DE69819340T2 (en) |
| DK (1) | DK1007527T3 (en) |
| ES (1) | ES2209196T3 (en) |
| FR (1) | FR2768431B1 (en) |
| HR (1) | HRP20000110A2 (en) |
| HU (1) | HUP0003429A3 (en) |
| IL (2) | IL134437A0 (en) |
| NO (1) | NO324882B1 (en) |
| NZ (1) | NZ502862A (en) |
| PL (1) | PL195289B1 (en) |
| PT (1) | PT1007527E (en) |
| RU (1) | RU2233283C2 (en) |
| TW (1) | TW419479B (en) |
| WO (1) | WO1999011646A1 (en) |
| ZA (1) | ZA987445B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2790261B1 (en) | 1999-02-26 | 2004-09-10 | Sod Conseils Rech Applic | NOVEL OPTICALLY PURE CAMPTOTHECIN ANALOGS AND PROCESSES FOR THEIR PREPARATION |
| US6207832B1 (en) | 1999-04-09 | 2001-03-27 | University Of Pittsburgh | Camptothecin analogs and methods of preparation thereof |
| US6372906B1 (en) | 2001-04-12 | 2002-04-16 | University Of Pittsburgh | Synthesis of silyl camptothecins and silyl homocamptothecins |
| US6723853B2 (en) | 2001-08-27 | 2004-04-20 | University Of Pittsburgh | Intermediates and methods of preparation of intermediates in the enantiomeric synthesis of (20R)homocamptothecins and the enantiomeric synthesis of (20R)homocamptothecins |
| CN100408582C (en) * | 2004-02-12 | 2008-08-06 | 中国人民解放军第二军医大学 | Homocamptothecin compound and its preparation method and use |
| EP1794127A1 (en) * | 2004-09-21 | 2007-06-13 | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) | Novel processes for the production of useful intermediates |
| CN100465175C (en) * | 2005-11-29 | 2009-03-04 | 中国人民解放军第二军医大学 | 7-position substituted homocamptothecin compound and its use as medicine |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3008226B2 (en) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | Hexacyclic compounds |
| US5459269A (en) * | 1992-06-18 | 1995-10-17 | North Carolina State University | 14-halo-camptothecins |
| FR2757514B1 (en) * | 1996-12-20 | 1999-02-12 | Sod Conseils Rech Applic | NOVEL CAMPTOTHECIN ANALOGS, PREPARATION METHODS, USE THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| EP0835258B1 (en) * | 1995-06-21 | 2002-09-25 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Novel camptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues |
-
1997
- 1997-08-29 FR FR9710785A patent/FR2768431B1/en not_active Expired - Fee Related
-
1998
- 1998-08-07 PT PT98941567T patent/PT1007527E/en unknown
- 1998-08-07 AU AU89896/98A patent/AU760863B2/en not_active Ceased
- 1998-08-07 NZ NZ502862A patent/NZ502862A/en unknown
- 1998-08-07 WO PCT/FR1998/001768 patent/WO1999011646A1/en not_active Ceased
- 1998-08-07 RU RU2000107822/04A patent/RU2233283C2/en not_active IP Right Cessation
- 1998-08-07 IL IL13443798A patent/IL134437A0/en active IP Right Grant
- 1998-08-07 DE DE69819340T patent/DE69819340T2/en not_active Expired - Lifetime
- 1998-08-07 EP EP03077049A patent/EP1378512A1/en not_active Withdrawn
- 1998-08-07 BR BR9811405-0A patent/BR9811405A/en not_active Application Discontinuation
- 1998-08-07 HU HU0003429A patent/HUP0003429A3/en unknown
- 1998-08-07 ES ES98941567T patent/ES2209196T3/en not_active Expired - Lifetime
- 1998-08-07 CN CN98808720A patent/CN1104434C/en not_active Expired - Lifetime
- 1998-08-07 HR HR20000110A patent/HRP20000110A2/en not_active Application Discontinuation
- 1998-08-07 KR KR1020007002034A patent/KR100570254B1/en not_active Expired - Fee Related
- 1998-08-07 PL PL98338835A patent/PL195289B1/en not_active IP Right Cessation
- 1998-08-07 AT AT98941567T patent/ATE253069T1/en active
- 1998-08-07 JP JP2000508685A patent/JP2001514261A/en active Pending
- 1998-08-07 CN CNB031021662A patent/CN1195758C/en not_active Expired - Fee Related
- 1998-08-07 DK DK98941567T patent/DK1007527T3/en active
- 1998-08-07 CZ CZ20000711A patent/CZ297896B6/en not_active IP Right Cessation
- 1998-08-07 EP EP98941567A patent/EP1007527B1/en not_active Expired - Lifetime
- 1998-08-07 CA CA002301739A patent/CA2301739C/en not_active Expired - Fee Related
- 1998-08-18 ZA ZA987445A patent/ZA987445B/en unknown
- 1998-08-19 TW TW087113646A patent/TW419479B/en not_active IP Right Cessation
- 1998-08-21 AR ARP980104157A patent/AR016856A1/en active IP Right Grant
-
2000
- 2000-02-08 IL IL134437A patent/IL134437A/en not_active IP Right Cessation
- 2000-02-28 NO NO20000995A patent/NO324882B1/en not_active IP Right Cessation
-
2003
- 2003-02-08 CN CN03102165A patent/CN1440972A/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |