IL128597A - An electrochemical detector integrated on tiny capillary chips with insulating parts movement in a charged solution - Google Patents

An electrochemical detector integrated on tiny capillary chips with insulating parts movement in a charged solution

Info

Publication number: IL128597A
Authority: IL; Israel
Prior art keywords: channel; thin film; electrode; capillary electrophoresis; electrophoresis chip
Prior art date: 1996-08-26

Application number

IL12859797A

Other languages

English (en)

Hebrew (he)

Other versions

IL128597A0 (en

Original Assignee

Univ California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-26

Filing date

1997-08-26

Publication date

2001-11-25

1996-08-26 Priority claimed from US08/703,394 external-priority patent/US5906723A/en

1997-08-26 Application filed by Univ California filed Critical Univ California

2000-01-31 Publication of IL128597A0 publication Critical patent/IL128597A0/xx

2001-11-25 Publication of IL128597A publication Critical patent/IL128597A/en

Links

238000005251 capillar electrophoresis Methods 0.000 title claims abstract description 59
238000000926 separation method Methods 0.000 claims abstract description 81
239000010409 thin film Substances 0.000 claims abstract description 45
238000001514 detection method Methods 0.000 claims abstract description 40
238000001962 electrophoresis Methods 0.000 claims abstract description 31
239000000758 substrate Substances 0.000 claims abstract description 18
238000006479 redox reaction Methods 0.000 claims abstract description 4
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VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
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QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 description 2
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SXGZJKUKBWWHRA-UHFFFAOYSA-N 2-(N-morpholiniumyl)ethanesulfonate Chemical compound [O-]S(=O)(=O)CC[NH+]1CCOCC1 SXGZJKUKBWWHRA-UHFFFAOYSA-N 0.000 description 1
HCAJQHYUCKICQH-VPENINKCSA-N 8-Oxo-7,8-dihydro-2'-deoxyguanosine Chemical compound C1=2NC(N)=NC(=O)C=2NC(=O)N1[C@H]1C[C@H](O)[C@@H](CO)O1 HCAJQHYUCKICQH-VPENINKCSA-N 0.000 description 1
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OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
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PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
229910052737 gold Inorganic materials 0.000 description 1
239000010931 gold Substances 0.000 description 1
XEOCKQIQXJNTER-UHFFFAOYSA-N gold palladium platinum Chemical compound [Pd].[Pd].[Pd].[Pd].[Pd].[Pt].[Pt].[Pt].[Pt].[Pt].[Pt].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au] XEOCKQIQXJNTER-UHFFFAOYSA-N 0.000 description 1
239000000383 hazardous chemical Substances 0.000 description 1
230000036541 health Effects 0.000 description 1
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238000006460 hydrolysis reaction Methods 0.000 description 1
235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
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238000001727 in vivo Methods 0.000 description 1
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238000009830 intercalation Methods 0.000 description 1
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LNQCJIZJBYZCME-UHFFFAOYSA-N iron(2+);1,10-phenanthroline Chemical compound [Fe+2].C1=CN=C2C3=NC=CC=C3C=CC2=C1.C1=CN=C2C3=NC=CC=C3C=CC2=C1.C1=CN=C2C3=NC=CC=C3C=CC2=C1 LNQCJIZJBYZCME-UHFFFAOYSA-N 0.000 description 1
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238000004544 sputter deposition Methods 0.000 description 1
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PIEPQKCYPFFYMG-UHFFFAOYSA-N tris acetate Chemical compound CC(O)=O.OCC(N)(CO)CO PIEPQKCYPFFYMG-UHFFFAOYSA-N 0.000 description 1
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Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/4473—Arrangements for investigating the separated zones, e.g. localising zones by electric means
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Electrochemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Dispersion Chemistry (AREA)
Investigating Or Analysing Biological Materials (AREA)
Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)

IL12859797A 1996-08-26 1997-08-26 An electrochemical detector integrated on tiny capillary chips with insulating parts movement in a charged solution IL128597A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/703,394 US5906723A (en)	1996-08-26	1996-08-26	Electrochemical detector integrated on microfabricated capillary electrophoresis chips
US08/916,557 US6045676A (en)	1996-08-26	1997-08-22	Electrochemical detector integrated on microfabricated capilliary electrophoresis chips
PCT/US1997/015006 WO1998009161A1 (fr)	1996-08-26	1997-08-26	Detecteur electrochimique integre a des puces pour electrophorese capillaire fabriquees par micro-usinage

Publications (2)

Publication Number	Publication Date
IL128597A0 IL128597A0 (en)	2000-01-31
IL128597A true IL128597A (en)	2001-11-25

Family

ID=27107131

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12859797A IL128597A (en)	1996-08-26	1997-08-26	An electrochemical detector integrated on tiny capillary chips with insulating parts movement in a charged solution

Country Status (10)

Country	Link
US (1)	US6045676A (fr)
EP (1)	EP0922218A1 (fr)
JP (1)	JP3474581B2 (fr)
KR (1)	KR100316437B1 (fr)
CN (1)	CN1235674A (fr)
AU (1)	AU714163B2 (fr)
CA (1)	CA2263859C (fr)
IL (1)	IL128597A (fr)
NZ (1)	NZ334181A (fr)
WO (1)	WO1998009161A1 (fr)

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1997
- 1997-08-22 US US08/916,557 patent/US6045676A/en not_active Expired - Lifetime
- 1997-08-26 NZ NZ334181A patent/NZ334181A/xx unknown
- 1997-08-26 AU AU40905/97A patent/AU714163B2/en not_active Ceased
- 1997-08-26 IL IL12859797A patent/IL128597A/en not_active IP Right Cessation
- 1997-08-26 EP EP97938617A patent/EP0922218A1/fr not_active Withdrawn
- 1997-08-26 CA CA002263859A patent/CA2263859C/fr not_active Expired - Fee Related
- 1997-08-26 JP JP51184298A patent/JP3474581B2/ja not_active Expired - Fee Related
- 1997-08-26 CN CN97197445A patent/CN1235674A/zh active Pending
- 1997-08-26 WO PCT/US1997/015006 patent/WO1998009161A1/fr not_active Ceased
- 1997-08-26 KR KR1019997001418A patent/KR100316437B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU714163B2 (en)	1999-12-23
EP0922218A1 (fr)	1999-06-16
US6045676A (en)	2000-04-04
IL128597A0 (en)	2000-01-31
JP3474581B2 (ja)	2003-12-08
CN1235674A (zh)	1999-11-17
WO1998009161A1 (fr)	1998-03-05
JP2001527637A (ja)	2001-12-25
NZ334181A (en)	2000-09-29
KR20000035802A (ko)	2000-06-26
CA2263859C (fr)	2003-07-01
CA2263859A1 (fr)	1998-03-05
KR100316437B1 (ko)	2001-12-12
AU4090597A (en)	1998-03-19

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