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IL125907A0 - Aminotetralin derivatives and compositions and method of use thereof - Google Patents

Aminotetralin derivatives and compositions and method of use thereof

Info

Publication number
IL125907A0
IL125907A0 IL12590797A IL12590797A IL125907A0 IL 125907 A0 IL125907 A0 IL 125907A0 IL 12590797 A IL12590797 A IL 12590797A IL 12590797 A IL12590797 A IL 12590797A IL 125907 A0 IL125907 A0 IL 125907A0
Authority
IL
Israel
Prior art keywords
hydrogen
compositions
aminotetralin derivatives
alkoxy
halogen
Prior art date
Application number
IL12590797A
Other languages
English (en)
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of IL125907A0 publication Critical patent/IL125907A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL12590797A 1996-03-01 1997-02-25 Aminotetralin derivatives and compositions and method of use thereof IL125907A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1264096P 1996-03-01 1996-03-01
PCT/GB1997/000516 WO1997031887A1 (en) 1996-03-01 1997-02-25 Aminotetralin derivatives and compositions and method of use thereof

Publications (1)

Publication Number Publication Date
IL125907A0 true IL125907A0 (en) 1999-04-11

Family

ID=21755962

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12590797A IL125907A0 (en) 1996-03-01 1997-02-25 Aminotetralin derivatives and compositions and method of use thereof

Country Status (14)

Country Link
US (1) US5807897A (ja)
EP (1) EP0883599B1 (ja)
JP (1) JP4083221B2 (ja)
KR (1) KR19990087369A (ja)
CN (1) CN1212682A (ja)
AT (1) ATE218535T1 (ja)
AU (1) AU733264B2 (ja)
DE (1) DE69713067T2 (ja)
IL (1) IL125907A0 (ja)
NO (1) NO983990L (ja)
NZ (1) NZ330974A (ja)
TW (1) TW409113B (ja)
WO (1) WO1997031887A1 (ja)
ZA (1) ZA971670B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726736D0 (en) * 1997-12-18 1998-02-18 Zeneca Ltd Chemical compounds
WO2000039105A1 (en) * 1998-12-24 2000-07-06 Astrazeneca Ab 1,4-diazacycloheptane derivatives useful in the treatment of neurological disorders
GB9914015D0 (en) * 1999-06-17 1999-08-18 Zeneca Ltd Chemical compounds
GB9914025D0 (en) * 1999-06-17 1999-08-18 Zeneca Ltd Chemical compounds
GB9914024D0 (en) * 1999-06-17 1999-08-18 Zeneca Ltd Chemical compounds
EP1658277B1 (en) * 2003-08-18 2012-04-04 H. Lundbeck A/S Succinate and malonate salt of trans-4-(ir,3s)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and the use as a medicament
TWI453198B (zh) * 2005-02-16 2014-09-21 Lundbeck & Co As H 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s）-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法
TWI376373B (en) * 2005-02-16 2012-11-11 Lundbeck & Co As H Crystalline base of a pharmaceutical compound
CA2722374A1 (en) * 2008-05-07 2009-11-12 H. Lundbeck A/S Method for treating cognitive deficits
CN102170884A (zh) * 2008-10-03 2011-08-31 H.隆德贝克有限公司 口服制剂
EP4351548A4 (en) 2021-06-08 2025-04-30 ATAI Therapeutics, Inc. Dimethoxyphenylalkylamine activators of serotonin receptors
JP2024547131A (ja) 2021-12-27 2024-12-26 エーティーエーアイ セラピューティクス，インコーポレイテッド セロトニン受容体のアミノテトラリン活性化剤
US12343319B2 (en) 2023-05-01 2025-07-01 Atai Therapeutics, Inc. Compositions and methods for treatment of diseases and disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320148A (en) * 1980-11-24 1982-03-16 Smithkline Corporation 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
SE8904127D0 (sv) * 1989-12-07 1989-12-07 Astra Ab New biocyclic amino-substituted compounds
EP0450238A1 (en) * 1990-03-30 1991-10-09 Merrell Dow Pharmaceuticals Inc. Novel compounds for the treatment of migraine

Also Published As

Publication number Publication date
NZ330974A (en) 2000-05-26
ZA971670B (en) 1997-09-01
NO983990D0 (no) 1998-08-31
CN1212682A (zh) 1999-03-31
DE69713067T2 (de) 2002-12-19
AU1887997A (en) 1997-09-16
JP2000506137A (ja) 2000-05-23
WO1997031887A1 (en) 1997-09-04
EP0883599A1 (en) 1998-12-16
KR19990087369A (ko) 1999-12-27
EP0883599B1 (en) 2002-06-05
DE69713067D1 (de) 2002-07-11
TW409113B (en) 2000-10-21
NO983990L (no) 1998-08-31
ATE218535T1 (de) 2002-06-15
JP4083221B2 (ja) 2008-04-30
US5807897A (en) 1998-09-15
AU733264B2 (en) 2001-05-10

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