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IL125340A0 - Novel immunophilin ligands with antiasthmatic and immunosuppressive action - Google Patents

Novel immunophilin ligands with antiasthmatic and immunosuppressive action

Info

Publication number
IL125340A0
IL125340A0 IL12534097A IL12534097A IL125340A0 IL 125340 A0 IL125340 A0 IL 125340A0 IL 12534097 A IL12534097 A IL 12534097A IL 12534097 A IL12534097 A IL 12534097A IL 125340 A0 IL125340 A0 IL 125340A0
Authority
IL
Israel
Prior art keywords
antiasthmatic
novel
immunosuppressive action
immunophilin ligands
immunophilin
Prior art date
Application number
IL12534097A
Other languages
English (en)
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of IL125340A0 publication Critical patent/IL125340A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12534097A 1996-04-25 1997-04-04 Novel immunophilin ligands with antiasthmatic and immunosuppressive action IL125340A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19616509A DE19616509A1 (de) 1996-04-25 1996-04-25 Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva
PCT/EP1997/001681 WO1997041148A1 (de) 1996-04-25 1997-04-04 Spezifische immunophilin-liganden als antiasthmatika, immunsuppressiva

Publications (1)

Publication Number Publication Date
IL125340A0 true IL125340A0 (en) 1999-03-12

Family

ID=7792406

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12534097A IL125340A0 (en) 1996-04-25 1997-04-04 Novel immunophilin ligands with antiasthmatic and immunosuppressive action

Country Status (20)

Country Link
US (1) US6258815B1 (is)
EP (1) EP0896580A1 (is)
JP (1) JP3102895B2 (is)
KR (1) KR20000065003A (is)
CN (1) CN1214690A (is)
AU (1) AU719840B2 (is)
BR (1) BR9708869A (is)
CA (1) CA2203466A1 (is)
CZ (1) CZ297298A3 (is)
DE (1) DE19616509A1 (is)
HU (1) HUP9901588A3 (is)
IL (1) IL125340A0 (is)
IS (1) IS4808A (is)
NO (1) NO984647L (is)
NZ (1) NZ331180A (is)
PL (1) PL329560A1 (is)
SK (1) SK143998A3 (is)
TR (1) TR199801949T2 (is)
WO (1) WO1997041148A1 (is)
ZA (1) ZA973121B (is)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19742263A1 (de) * 1997-09-25 1999-04-01 Asta Medica Ag Neue spezifische Immunophilin-Liganden als Antiasthmatika, Antiallergika, Antirheumatika, Immunsuppressiva, Antipsoriatika, Neuroprotektiva
US6251932B1 (en) 1998-09-25 2001-06-26 Asta Medica Ag Immunophilin ligands
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
CN112022846B (zh) * 2020-09-23 2021-10-08 吕奔 一种吲哚啉衍生物在制备治疗脓毒症药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2585709B1 (fr) 1985-08-05 1987-10-02 Adir Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE3742431A1 (de) * 1987-12-15 1989-07-13 Hoechst Ag Neue derivate cyclischer aminosaeuren, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung
JPH0712045B2 (ja) 1988-03-02 1995-02-08 株式会社東海理化電機製作所 電流検出素子
US5192773A (en) * 1990-07-02 1993-03-09 Vertex Pharmaceuticals, Inc. Immunosuppressive compounds
FR2681864B1 (fr) 1991-09-27 1995-03-31 Adir Nouveaux derives bicycliques azotes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
JP3810097B2 (ja) * 1993-01-15 2006-08-16 明治製菓株式会社 ピロリジン−2−イルカルボニル複素環式化合物誘導体
FR2703050B1 (fr) * 1993-03-24 1995-04-28 Adir Nouveaux dérivés bicycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
US6258815B1 (en) 2001-07-10
CA2203466A1 (en) 1997-10-25
TR199801949T2 (xx) 1999-02-22
NO984647D0 (no) 1998-10-05
EP0896580A1 (de) 1999-02-17
JP2000500776A (ja) 2000-01-25
KR20000065003A (ko) 2000-11-06
DE19616509A1 (de) 1998-01-15
CN1214690A (zh) 1999-04-21
WO1997041148A1 (de) 1997-11-06
IS4808A (is) 1998-07-24
BR9708869A (pt) 1999-08-03
NO984647L (no) 1998-10-05
JP3102895B2 (ja) 2000-10-23
AU2508297A (en) 1997-11-19
NZ331180A (en) 2000-04-28
ZA973121B (en) 1997-11-05
HUP9901588A2 (hu) 1999-08-30
AU719840B2 (en) 2000-05-18
PL329560A1 (en) 1999-03-29
CZ297298A3 (cs) 1999-03-17
SK143998A3 (en) 1999-08-06
HUP9901588A3 (en) 2000-06-28

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