IL111928A - Long acting poorly soluble salts of peptides and pharmaceutical compositions containing them - Google Patents

Long acting poorly soluble salts of peptides and pharmaceutical compositions containing them

Info

Publication number: IL111928A
Authority: IL; Israel
Prior art keywords: soluble salts; poorly soluble; peptides; pharmaceutical compositions; compositions containing
Prior art date: 1993-12-09

Application number

IL11192894A

Other languages

English (en)

Other versions

IL111928A0 (en

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-09

Filing date

1994-12-08

Publication date

1999-11-30

1994-12-08 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

1995-03-15 Publication of IL111928A0 publication Critical patent/IL111928A0/xx

1996-06-10 Priority claimed from US08/661,017 external-priority patent/US5773032A/en

1999-11-30 Publication of IL111928A publication Critical patent/IL111928A/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
- A61K38/105—Bombesin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL11192894A 1993-12-09 1994-12-08 Long acting poorly soluble salts of peptides and pharmaceutical compositions containing them IL111928A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4342092A DE4342092B4 (de)	1993-12-09	1993-12-09	Langwirkende Injektionssuspension und Verfahren zur Herstellung
US08/661,017 US5773032A (en)	1993-12-09	1996-06-10	Long-acting injection suspensions and a process for their preparation

Publications (2)

Publication Number	Publication Date
IL111928A0 IL111928A0 (en)	1995-03-15
IL111928A true IL111928A (en)	1999-11-30

Family

ID=25931926

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL11192894A IL111928A (en)	1993-12-09	1994-12-08	Long acting poorly soluble salts of peptides and pharmaceutical compositions containing them

Country Status (26)

Country	Link
EP (1)	EP0732934B1 (de)
JP (1)	JPH09509145A (de)
CN (2)	CN1248732C (de)
AT (1)	ATE310530T1 (de)
AU (1)	AU677748B2 (de)
BR (1)	BR9408272A (de)
CZ (1)	CZ291025B6 (de)
DE (1)	DE4342092B4 (de)
DK (1)	DK0732934T3 (de)
EE (1)	EE03224B1 (de)
EG (1)	EG20787A (de)
ES (1)	ES2251715T3 (de)
FI (1)	FI116121B (de)
HR (1)	HRP940978B1 (de)
HU (1)	HU217081B (de)
IL (1)	IL111928A (de)
LV (1)	LV11596B (de)
NO (1)	NO318984B1 (de)
NZ (1)	NZ277239A (de)
PL (1)	PL186929B1 (de)
RO (1)	RO119343B1 (de)
RS (1)	RS49511B (de)
RU (1)	RU2152222C1 (de)
SK (2)	SK284981B6 (de)
WO (1)	WO1995015767A1 (de)
ZA (1)	ZA949798B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6828415B2 (en) *	1993-02-19	2004-12-07	Zentaris Gmbh	Oligopeptide lyophilisate, their preparation and use
UA44722C2 (uk) *	1993-12-09	2002-03-15	Аста Медіка Акціенгезельшафт	Лікарський засіб пролонгованої дії для зниження рівня тестостерону
WO1998032423A1 (en) *	1997-01-29	1998-07-30	Takeda Chemical Industries, Ltd.	Sustained-release microspheres, their production and use
DE10040700A1 (de) *	2000-08-17	2002-02-28	Asta Medica Ag	Salze von biologisch aktiven Peptiden, ihre Herstellung und Verwendung
WO2002047722A1 (en) *	2000-12-15	2002-06-20	Takeda Chemical Industries, Ltd.	Medicinal compositions of nonpeptidyl gonadotropin-releasing hormone agonist or antagonist, process for producing the same and use thereof
TWI332407B (en)	2001-06-29	2010-11-01	Takeda Chemical Industries Ltd	Controlled release composition and method of producting the same
US7098305B2 (en) *	2001-09-06	2006-08-29	Ardana Bioscience Limited	Sustained release of microcrystalline peptide suspensions
EP1674082A1 (de)	2004-12-22	2006-06-28	Zentaris GmbH	Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel
AR064381A1 (es)	2006-12-18	2009-04-01	Takeda Pharmaceutical	Composicion de liberacion sostenida y metodos para producirla
JP5486690B2 (ja)	2009-11-16	2014-05-07	イプセンファルマソシエテパールアクシオンサンプリフィエ	メラノコルチン受容体リガンドの医薬組成物
CN102504018A (zh) *	2011-10-28	2012-06-20	沈阳药科大学	可持续释放的蜂毒肽帕莫酸盐及其制剂
AU2017242867B9 (en) *	2016-03-29	2019-07-04	Shanghai Synergy Pharmaceutical Sciences Co., Ltd	Vortioxetine pamoic acid salt and crystal form thereof
CN108969478A (zh) *	2018-08-29	2018-12-11	江南大学	一种美金刚难溶盐缓释注射剂及其制备方法
CN110003195B (zh) *	2019-05-21	2020-05-26	湖北中医药大学	鲁拉西酮晶体及其制备方法和在注射给药系统中的应用
CN112569340A (zh) *	2020-12-31	2021-03-30	苏州素仕生物科技有限公司	一种无菌布舍瑞林注射液及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3852422A (en) *	1971-06-26	1974-12-03	Serono Ist Farm	Long-active gonadotropins
NZ181036A (en) *	1975-06-12	1978-12-18	A Schally	Luteinising hormone releasing hormone analogues and intermediates therefor
GB2209937B (en) *	1987-09-21	1991-07-03	Depiopharm S A	Water insoluble polypeptides
FR2647677B1 (fr) *	1989-05-31	1991-09-27	Roussel Uclaf	Nouvelles micro-proteines, procede de preparation et application a titre de medicaments de ces nouvelles micro-proteines
CH679207A5 (de) *	1989-07-28	1992-01-15	Debiopharm Sa
CH683149A5 (fr) *	1991-07-22	1994-01-31	Debio Rech Pharma Sa	Procédé pour la préparation de microsphères en matériau polymère biodégradable.

1993
- 1993-12-09 DE DE4342092A patent/DE4342092B4/de not_active Expired - Fee Related
1994
- 1994-11-25 SK SK5090-2005A patent/SK284981B6/sk not_active IP Right Cessation
- 1994-11-25 JP JP7515921A patent/JPH09509145A/ja not_active Ceased
- 1994-11-25 ES ES95903282T patent/ES2251715T3/es not_active Expired - Lifetime
- 1994-11-25 EE EE9600061A patent/EE03224B1/xx not_active IP Right Cessation
- 1994-11-25 HU HU9601584A patent/HU217081B/hu not_active IP Right Cessation
- 1994-11-25 SK SK667-96A patent/SK284980B6/sk not_active IP Right Cessation
- 1994-11-25 CN CNB021593949A patent/CN1248732C/zh not_active Expired - Fee Related
- 1994-11-25 CZ CZ19961420A patent/CZ291025B6/cs not_active IP Right Cessation
- 1994-11-25 WO PCT/EP1994/003904 patent/WO1995015767A1/en not_active Ceased
- 1994-11-25 EP EP95903282A patent/EP0732934B1/de not_active Expired - Lifetime
- 1994-11-25 RU RU96115021/14A patent/RU2152222C1/ru not_active IP Right Cessation
- 1994-11-25 BR BR9408272A patent/BR9408272A/pt not_active Application Discontinuation
- 1994-11-25 NZ NZ277239A patent/NZ277239A/en not_active IP Right Cessation
- 1994-11-25 RO RO96-01143A patent/RO119343B1/ro unknown
- 1994-11-25 AT AT95903282T patent/ATE310530T1/de not_active IP Right Cessation
- 1994-11-25 DK DK95903282T patent/DK0732934T3/da active
- 1994-11-25 CN CNB941944050A patent/CN1136916C/zh not_active Expired - Fee Related
- 1994-11-25 PL PL94314913A patent/PL186929B1/pl not_active IP Right Cessation
- 1994-11-25 AU AU12199/95A patent/AU677748B2/en not_active Ceased
- 1994-12-07 EG EG77194A patent/EG20787A/xx active
- 1994-12-08 RS YU72194A patent/RS49511B/sr unknown
- 1994-12-08 ZA ZA949798A patent/ZA949798B/xx unknown
- 1994-12-08 IL IL11192894A patent/IL111928A/xx not_active IP Right Cessation
- 1994-12-08 HR HR940978A patent/HRP940978B1/xx not_active IP Right Cessation
1996
- 1996-05-09 NO NO19961877A patent/NO318984B1/no not_active IP Right Cessation
- 1996-06-06 FI FI962354A patent/FI116121B/fi not_active IP Right Cessation
- 1996-07-09 LV LVP-96-226A patent/LV11596B/en unknown

Also Published As

Publication number	Publication date
LV11596A (lv)	1996-12-20
EE03224B1 (et)	1999-10-15
EP0732934B1 (de)	2005-11-23
AU1219995A (en)	1995-06-27
CN1494919A (zh)	2004-05-12
CZ291025B6 (cs)	2002-12-11
IL111928A0 (en)	1995-03-15
PL186929B1 (pl)	2004-04-30
ES2251715T3 (es)	2006-05-01
AU677748B2 (en)	1997-05-01
HRP940978B1 (en)	2006-08-31
DE4342092B4 (de)	2007-01-11
JPH09509145A (ja)	1997-09-16
NO961877D0 (no)	1996-05-09
FI962354A0 (fi)	1996-06-06
FI116121B (fi)	2005-09-30
YU72194A (sh)	1997-03-07
CN1248732C (zh)	2006-04-05
FI962354L (fi)	1996-06-06
NO318984B1 (no)	2005-05-30
HU9601584D0 (en)	1996-08-28
DE4342092A1 (de)	1995-06-14
WO1995015767A1 (en)	1995-06-15
CN1136779A (zh)	1996-11-27
LV11596B (en)	1997-06-20
RU2152222C1 (ru)	2000-07-10
EP0732934A1 (de)	1996-09-25
CZ142096A3 (en)	1996-12-11
RO119343B1 (ro)	2004-08-30
DK0732934T3 (da)	2006-03-27
BR9408272A (pt)	1996-12-17
NZ277239A (en)	1997-03-24
HK1063746A1 (en)	2005-01-14
SK66796A3 (en)	1997-08-06
ZA949798B (en)	1995-08-18
CN1136916C (zh)	2004-02-04
EG20787A (en)	2000-02-29
NO961877L (no)	1996-05-09
SK284981B6 (sk)	2006-03-02
PL314913A1 (en)	1996-09-30
SK284980B6 (sk)	2006-03-02
HRP940978A2 (en)	1997-02-28
HU217081B (hu)	1999-11-29
RS49511B (sr)	2006-10-27
ATE310530T1 (de)	2005-12-15
HUT75712A (en)	1997-05-28

Publication	Publication Date	Title
IL111928A (en)	1999-11-30	Long acting poorly soluble salts of peptides and pharmaceutical compositions containing them
EP2016950A8 (de)	2009-07-01	Pharmazeutische Zusammensetzung mit einem Exedin-4-Peptid
CA2203033A1 (en)	1996-05-02	Compounds and compositions for delivering active agents
CA2153584A1 (en)	1995-05-18	Cytokine restraining agents
AP9901702A0 (en)	1999-12-31	LH-RH peptide analogues their uses and pharmaceutical compositions containing them
FR2688422B1 (de)	1995-03-10
GR3029791T3 (en)	1999-06-30	Improved immunogenic compositions against human gastrin 17
MY107381A (en)	1995-11-30	Pharmaceutical compositions comprising cyclosporins.
CA2189250A1 (en)	1996-09-12	Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels
AU6819294A (en)	1994-11-08	Oral drug delivery compositions and methods
CA2338358A1 (en)	2000-02-10	Compounds and compositions for delivering active agents
CA2177772A1 (en)	1996-12-08	Pharmaceutical compositions containing irbesartan
CA2354034A1 (en)	2000-06-15	Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period
ATE146360T1 (de)	1997-01-15	Gonadotropin enthaltende gefriergetrocknete troepfen
CA2178592A1 (en)	1995-06-15	Long-acting injection suspensions and a process for their preparation
TW327602B (en)	1998-03-01	A pharmaceutical composition of an ophthalmic suspension containing difluprednate
CA2273272A1 (en)	1999-04-15	Immediate release drug delivery forms
CA2185883A1 (en)	1995-09-28	The use of dimeticone as a transport and carrier system and/or drug delivery system
ZA9710254B (en)	1998-05-28	LH-RH peptide analogues, their uses and pharmaceutical composition containing them.
TR199800954T2 (xx)	1998-10-21	Y�ksek i�erikli famsiklovir tabletleri.
MY119896A (en)	2005-08-30	Long-acting injection suspensions and a process for their preparation.
BG102514A (en)	1999-04-30	New lh-rh-antagonists of improved effect
AU7533394A (en)	1995-02-28	Antiacid pharmaceutical composition in the form of a suspension based on sucralphate gel

Legal Events

Date	Code	Title
2000-06-01	FF	Patent granted
2000-08-31	KB	Patent renewed
2002-06-30	HP	Change in proprietorship
2005-02-20	KB	Patent renewed
2009-06-15	KB	Patent renewed
2013-07-31	MM9K	Patent not in force due to non-payment of renewal fees