IL109870A - PROCESS FOR PREPARING CRYSTALLINE b-LACTAM MONOHYDRATE - Google Patents

PROCESS FOR PREPARING CRYSTALLINE b-LACTAM MONOHYDRATE

Info

Publication number: IL109870A
Authority: IL; Israel
Prior art keywords: crystal; monohydrate; crystalline; compound; dmf
Prior art date: 1993-06-04

Application number

IL109870A

Other languages

English (en)

Other versions

IL109870A0 (en

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-04

Filing date

1994-06-02

Publication date

1998-06-15

1994-06-02 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1994-10-07 Publication of IL109870A0 publication Critical patent/IL109870A0/xx

1998-06-15 Publication of IL109870A publication Critical patent/IL109870A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cephalosporin Compounds (AREA)

IL109870A 1993-06-04 1994-06-02 PROCESS FOR PREPARING CRYSTALLINE b-LACTAM MONOHYDRATE IL109870A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/071,552 US5352782A (en)	1993-06-04	1993-06-04	Process for preparing crystalline β-lactam monohydrate

Publications (2)

Publication Number	Publication Date
IL109870A0 IL109870A0 (en)	1994-10-07
IL109870A true IL109870A (en)	1998-06-15

Family

ID=22102062

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL109870A IL109870A (en)	1993-06-04	1994-06-02	PROCESS FOR PREPARING CRYSTALLINE b-LACTAM MONOHYDRATE

Country Status (29)

Country	Link
US (1)	US5352782A (es)
EP (1)	EP0627431B1 (es)
JP (1)	JPH06345761A (es)
KR (1)	KR950000702A (es)
CN (1)	CN1045296C (es)
AT (1)	ATE156129T1 (es)
AU (1)	AU682503B2 (es)
BR (1)	BR9402150A (es)
CA (1)	CA2125000A1 (es)
CO (1)	CO4230099A1 (es)
CZ (1)	CZ284225B6 (es)
DE (1)	DE69404560T2 (es)
DK (1)	DK0627431T3 (es)
ES (1)	ES2105524T3 (es)
FI (1)	FI942632A7 (es)
GR (1)	GR3024989T3 (es)
HU (1)	HU217067B (es)
IL (1)	IL109870A (es)
MY (1)	MY110725A (es)
NO (1)	NO307052B1 (es)
NZ (1)	NZ260652A (es)
PE (1)	PE13295A1 (es)
PH (1)	PH30184A (es)
PL (1)	PL174535B1 (es)
RU (1)	RU2130456C1 (es)
TW (1)	TW449596B (es)
UA (1)	UA34440C2 (es)
YU (1)	YU33494A (es)
ZA (1)	ZA943826B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5399686A (en) *	1993-06-04	1995-03-21	Eli Lilly And Company	Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5550231A (en) *	1993-06-15	1996-08-27	Eli Lilly And Company	Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5580977A (en) *	1995-03-01	1996-12-03	Eli Lilly And Company	Process for preparing loracarbef monohydrate
AU2003283624A1 (en) *	2002-11-21	2004-06-15	Ranbaxy Laboratories Limited	Monohydrate solvates of loracarbef

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3502663A (en) *	1969-04-21	1970-03-24	Lilly Co Eli	Crystalline cephalosporin,method for its manufacture
US3531481A (en) *	1969-04-21	1970-09-29	Lilly Co Eli	Method for manufacture of crystalline cephalosporin
ZA887409B (en) *	1987-10-06	1990-06-27	Lilly Co Eli	Crystalline beta-lactam hydrate
CA2002596A1 (en) *	1988-11-14	1990-05-14	Thomas M. Eckrich	Hydrates of b-lactam antibiotic
CA2002597C (en) *	1988-11-14	1999-03-23	Thomas M. Eckrich	Solvates of b-lactam antibiotic
US4977257A (en) *	1988-11-14	1990-12-11	Eli Lilly And Company	DMF solvates of a β-lactam antibiotic
CA2034592C (en) *	1990-01-26	2001-06-05	Ralph R. Pfeiffer	Crystalline hydrochloride of new beta-lactam antibiotic and process therefor

1993
- 1993-06-04 US US08/071,552 patent/US5352782A/en not_active Expired - Lifetime
1994
- 1994-06-01 CZ CZ941341A patent/CZ284225B6/cs not_active IP Right Cessation
- 1994-06-01 BR BR9402150A patent/BR9402150A/pt not_active Application Discontinuation
- 1994-06-01 DK DK94303946.1T patent/DK0627431T3/da active
- 1994-06-01 NZ NZ260652A patent/NZ260652A/en unknown
- 1994-06-01 ZA ZA943826A patent/ZA943826B/xx unknown
- 1994-06-01 PL PL94303677A patent/PL174535B1/pl unknown
- 1994-06-01 TW TW083105007A patent/TW449596B/zh not_active IP Right Cessation
- 1994-06-01 AT AT94303946T patent/ATE156129T1/de not_active IP Right Cessation
- 1994-06-01 EP EP94303946A patent/EP0627431B1/en not_active Expired - Lifetime
- 1994-06-01 DE DE69404560T patent/DE69404560T2/de not_active Expired - Fee Related
- 1994-06-01 ES ES94303946T patent/ES2105524T3/es not_active Expired - Lifetime
- 1994-06-01 PE PE1994243645A patent/PE13295A1/es not_active Application Discontinuation
- 1994-06-02 UA UA94005240A patent/UA34440C2/uk unknown
- 1994-06-02 CO CO94023736A patent/CO4230099A1/es unknown
- 1994-06-02 CA CA002125000A patent/CA2125000A1/en not_active Abandoned
- 1994-06-02 IL IL109870A patent/IL109870A/en not_active IP Right Cessation
- 1994-06-02 KR KR1019940012341A patent/KR950000702A/ko not_active Abandoned
- 1994-06-02 NO NO942049A patent/NO307052B1/no not_active IP Right Cessation
- 1994-06-02 AU AU64517/94A patent/AU682503B2/en not_active Ceased
- 1994-06-02 MY MYPI94001409A patent/MY110725A/en unknown
- 1994-06-02 PH PH48387A patent/PH30184A/en unknown
- 1994-06-03 HU HU9401674A patent/HU217067B/hu not_active IP Right Cessation
- 1994-06-03 CN CN94106983A patent/CN1045296C/zh not_active Expired - Fee Related
- 1994-06-03 JP JP6122282A patent/JPH06345761A/ja active Pending
- 1994-06-03 FI FI942632A patent/FI942632A7/fi unknown
- 1994-06-03 YU YU33494A patent/YU33494A/sh unknown
- 1994-06-03 RU RU94019423A patent/RU2130456C1/ru active
1997
- 1997-10-09 GR GR970402632T patent/GR3024989T3/el unknown

Also Published As

Publication number	Publication date
HUT67975A (en)	1995-05-29
NO942049L (no)	1994-12-05
HU9401674D0 (en)	1994-09-28
DE69404560D1 (de)	1997-09-04
AU6451794A (en)	1994-12-08
CN1045296C (zh)	1999-09-29
NO942049D0 (no)	1994-06-02
BR9402150A (pt)	1994-12-27
PL303677A1 (en)	1995-01-09
FI942632L (fi)	1994-12-05
PH30184A (en)	1997-01-21
CO4230099A1 (es)	1995-10-19
ES2105524T3 (es)	1997-10-16
AU682503B2 (en)	1997-10-09
PE13295A1 (es)	1995-05-24
CA2125000A1 (en)	1994-12-05
CZ284225B6 (cs)	1998-09-16
RU2130456C1 (ru)	1999-05-20
FI942632A0 (fi)	1994-06-03
JPH06345761A (ja)	1994-12-20
CN1097755A (zh)	1995-01-25
CZ134194A3 (en)	1994-12-15
NO307052B1 (no)	2000-01-31
RU94019423A (ru)	1996-04-20
MY110725A (en)	1999-01-30
IL109870A0 (en)	1994-10-07
ATE156129T1 (de)	1997-08-15
EP0627431A1 (en)	1994-12-07
US5352782A (en)	1994-10-04
HU217067B (hu)	1999-11-29
TW449596B (en)	2001-08-11
PL174535B1 (pl)	1998-08-31
UA34440C2 (uk)	2001-03-15
YU33494A (sh)	1996-10-18
DK0627431T3 (da)	1997-08-25
NZ260652A (en)	1995-09-26
DE69404560T2 (de)	1997-12-18
KR950000702A (ko)	1995-01-03
ZA943826B (en)	1995-12-01
GR3024989T3 (en)	1998-01-30
EP0627431B1 (en)	1997-07-30
FI942632A7 (fi)	1994-12-05

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Legal Events

Date	Code	Title
1998-11-26	FF	Patent granted
1999-04-11	KB	Patent renewed
2005-07-25	MM9K	Patent not in force due to non-payment of renewal fees