IE872951L - Composition for use in hypertension - Google Patents
Composition for use in hypertensionInfo
- Publication number
- IE872951L IE872951L IE872951A IE295187A IE872951L IE 872951 L IE872951 L IE 872951L IE 872951 A IE872951 A IE 872951A IE 295187 A IE295187 A IE 295187A IE 872951 L IE872951 L IE 872951L
- Authority
- IE
- Ireland
- Prior art keywords
- hypertension
- composition
- ca1314222c
- dithia
- azaspiro
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title abstract 2
- 239000005541 ACE inhibitor Substances 0.000 abstract 1
- 229940127291 Calcium channel antagonist Drugs 0.000 abstract 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
- 239000000480 calcium channel blocker Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A pharmaceutical composition for use against hypertension and congestive heart failure containing a) A calcium antagonist and b) the ACE-inhibitor 7-(N-¢1-(S)-Ethoxycarbonyl-3-phenylpropyl!-(S)-alanyl)-1,4-dithia-7-azaspiro-¢4,4!nonane-8-(S)-carboxylic acid.
[CA1314222C]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868626217A GB8626217D0 (en) | 1986-11-03 | 1986-11-03 | Pharmaceutical compositions |
| GB878713349A GB8713349D0 (en) | 1987-06-08 | 1987-06-08 | Pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE872951L true IE872951L (en) | 1988-05-03 |
| IE60496B1 IE60496B1 (en) | 1994-07-27 |
Family
ID=26291485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE295187A IE60496B1 (en) | 1986-11-03 | 1987-11-02 | Pharmaceutical composition for use against hypertension and congestive heart failure |
Country Status (25)
| Country | Link |
|---|---|
| KR (1) | KR960005145B1 (en) |
| AT (1) | AT397343B (en) |
| AU (1) | AU615883B2 (en) |
| BE (1) | BE1002063A4 (en) |
| CA (1) | CA1314222C (en) |
| CH (1) | CH677189A5 (en) |
| DE (1) | DE3736505A1 (en) |
| DK (1) | DK574087A (en) |
| ES (1) | ES2010524A6 (en) |
| FI (1) | FI874823A7 (en) |
| FR (1) | FR2605885B1 (en) |
| GR (1) | GR871680B (en) |
| HK (1) | HK138893A (en) |
| HU (1) | HU199681B (en) |
| IE (1) | IE60496B1 (en) |
| IL (1) | IL84343A (en) |
| IT (1) | IT1212037B (en) |
| LU (1) | LU87034A1 (en) |
| MY (1) | MY102124A (en) |
| NL (1) | NL8702502A (en) |
| NO (1) | NO874539L (en) |
| NZ (1) | NZ222401A (en) |
| PH (1) | PH23249A (en) |
| PT (1) | PT86062B (en) |
| SE (1) | SE8704272L (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3818245A1 (en) * | 1988-05-28 | 1989-12-07 | Hoechst Ag | COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS WITH COLD CHANNEL MODULATORS AND THEIR USE IN MEDICINAL PRODUCTS |
| FR2733911B1 (en) * | 1995-05-09 | 1998-05-29 | Takeda Chemical Industries Ltd | PHARMACEUTICAL COMPOSITION FOR RENAL OR CARDIOVASCULAR DISEASES |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4470972A (en) * | 1981-04-28 | 1984-09-11 | Schering Corporation | 7-Carboxyalkylaminoacyl-1,4-dithia-7-azaspiro[4.4]-nonane-8-carboxylic acids |
| US4520021A (en) * | 1982-07-02 | 1985-05-28 | Merck & Co., Inc. | Substituted caprolactam derivatives as antihypertensives |
| DE3437917A1 (en) * | 1984-10-17 | 1986-04-17 | Bayer Ag, 5090 Leverkusen | COMBINATION OF DIHYDROPYRIDINE WITH ACE INHIBITORS AND THEIR USE IN MEDICINAL PRODUCTS |
| DE3633496A1 (en) * | 1986-10-02 | 1988-04-14 | Hoechst Ag | COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS WITH CALCIUMANTAGONISTS AND THEIR USE IN MEDICINAL PRODUCTS |
| GB2198641B (en) * | 1986-11-03 | 1990-09-19 | Sandoz Ltd | Pharmaceutical composition for use against hypertension and congestive heart failure |
| IL88502A (en) * | 1987-12-14 | 1993-04-04 | Squibb & Sons Inc | Pharmaceutical compositions containing an angiotensin converting enzyme inhibitor |
-
1987
- 1987-10-20 HU HU874712A patent/HU199681B/en not_active IP Right Cessation
- 1987-10-20 NL NL8702502A patent/NL8702502A/en not_active Application Discontinuation
- 1987-10-28 DE DE19873736505 patent/DE3736505A1/en not_active Ceased
- 1987-10-28 CH CH4224/87A patent/CH677189A5/de not_active IP Right Cessation
- 1987-10-30 FR FR8715186A patent/FR2605885B1/en not_active Expired - Fee Related
- 1987-10-30 IT IT8748553A patent/IT1212037B/en active
- 1987-10-30 CA CA000551575A patent/CA1314222C/en not_active Expired - Fee Related
- 1987-10-30 BE BE8701236A patent/BE1002063A4/en not_active IP Right Cessation
- 1987-10-30 LU LU87034A patent/LU87034A1/en unknown
- 1987-11-02 PT PT86062A patent/PT86062B/en not_active IP Right Cessation
- 1987-11-02 AU AU80576/87A patent/AU615883B2/en not_active Ceased
- 1987-11-02 IL IL84343A patent/IL84343A/en unknown
- 1987-11-02 DK DK574087A patent/DK574087A/en not_active Application Discontinuation
- 1987-11-02 NO NO874539A patent/NO874539L/en unknown
- 1987-11-02 KR KR1019870012319A patent/KR960005145B1/en not_active Expired - Lifetime
- 1987-11-02 NZ NZ222401A patent/NZ222401A/en unknown
- 1987-11-02 FI FI874823A patent/FI874823A7/en not_active Application Discontinuation
- 1987-11-02 IE IE295187A patent/IE60496B1/en not_active IP Right Cessation
- 1987-11-02 GR GR871680A patent/GR871680B/en unknown
- 1987-11-02 AT AT0286987A patent/AT397343B/en not_active IP Right Cessation
- 1987-11-02 MY MYPI87003005A patent/MY102124A/en unknown
- 1987-11-02 SE SE8704272A patent/SE8704272L/en unknown
- 1987-11-03 PH PH36019A patent/PH23249A/en unknown
- 1987-11-03 ES ES8703141A patent/ES2010524A6/en not_active Expired
-
1993
- 1993-12-16 HK HK1388/93A patent/HK138893A/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |