[go: up one dir, main page]

IE812915L - ESTERS OF 7ß-SUBSTITUTED CEPH-3-EM-4-CARBOXYLIC ACIDS - Google Patents

ESTERS OF 7ß-SUBSTITUTED CEPH-3-EM-4-CARBOXYLIC ACIDS

Info

Publication number
IE812915L
IE812915L IE812915A IE291581A IE812915L IE 812915 L IE812915 L IE 812915L IE 812915 A IE812915 A IE 812915A IE 291581 A IE291581 A IE 291581A IE 812915 L IE812915 L IE 812915L
Authority
IE
Ireland
Prior art keywords
esters
carboxylic acids
ceph
substituted
substituted ceph
Prior art date
Application number
IE812915A
Other versions
IE52008B1 (en
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IE812915L publication Critical patent/IE812915L/en
Publication of IE52008B1 publication Critical patent/IE52008B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to novel 1- loweralkoxycarbonyl-oxy-lower alkyl esters of 7 beta -[2-(2-amino-4-thiazolyl)-2- (syn)-methoxyimino-acetamido]-3- cephem-4-carboxylic acid and N- protected derivatives thereof, which esters can be split under physiological conditions, to processes for producing them, and to pharmaceutical preparations containing such antibacterially active compounds. [EP0054512A2]
IE2915/81A 1980-12-12 1981-12-11 Novel esters IE52008B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH919680 1980-12-12

Publications (2)

Publication Number Publication Date
IE812915L true IE812915L (en) 1982-06-12
IE52008B1 IE52008B1 (en) 1987-05-13

Family

ID=4349398

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2915/81A IE52008B1 (en) 1980-12-12 1981-12-11 Novel esters

Country Status (18)

Country Link
EP (1) EP0054512A3 (en)
JP (1) JPS57123190A (en)
KR (1) KR830007683A (en)
AR (1) AR231984A1 (en)
AU (1) AU7846681A (en)
DD (1) DD208155A5 (en)
DK (1) DK550081A (en)
ES (6) ES507907A0 (en)
FI (1) FI813946L (en)
GB (1) GB2111043B (en)
GR (1) GR76967B (en)
HU (1) HU185985B (en)
IE (1) IE52008B1 (en)
IL (1) IL64506A (en)
NO (1) NO814232L (en)
NZ (1) NZ199255A (en)
PT (1) PT74119B (en)
ZA (1) ZA818622B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1142096B (en) * 1980-12-15 1986-10-08 Fujisawa Pharmaceutical Co 7-ACHYLAMINE CEPHALOSPORANIC ACID DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION
JPS57156495A (en) * 1981-03-23 1982-09-27 Kyoto Yakuhin Kogyo Kk Cephalosporin derivative and remedy for microbism used in oral administration
IT1190897B (en) * 1982-06-29 1988-02-24 Opos Biochimica Srl PROCEDURE FOR THE PREPARATION OF THE 1-ETHOXYCARBONYLOXYETHYL ACID ACID 6- (D (-) - ALPHA AMINOALPHA-PHENYLACETAMIDE) -PENICILLANIC
US4606865A (en) * 1982-09-20 1986-08-19 Astra Lakemedel Aktiebolag Methods for the preparation of α-bromodiethylcarbonate
JPS59116291A (en) * 1982-12-06 1984-07-05 Fujisawa Pharmaceut Co Ltd 7-substituted-3-cephem-4-carboxylic acid ester and its preparation
US5202454A (en) * 1986-07-11 1993-04-13 Societe Nationale Des Poudres Et Explosifs Process for the manufacture of 1-bromoalkyl hydrocarbyl carbonates
KR0173796B1 (en) * 1989-10-28 1999-02-01 기까미 기즈히꼬 Cephalosporin compound and preparation method thereof
DK0915894T3 (en) * 1996-07-26 2003-09-15 Gilead Sciences Inc nucleotide analogs
KR20080032014A (en) 2003-01-14 2008-04-11 길리애드 사이언시즈, 인코포레이티드 Compositions and Methods for Combination Antiviral Therapy
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (en) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc Unitary pharmaceutical dosage form

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3965099A (en) * 1974-06-26 1976-06-22 Smithkline Corporation Cephalosporin esters with antibacterial activity
JPS5321192A (en) * 1976-08-10 1978-02-27 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
ZA793391B (en) * 1978-07-07 1980-06-25 Ciba Geigy Ag Aminothiazole compounds
MA18686A1 (en) * 1978-07-07 1980-10-01 Ciba Geigy Ag AMINOTHIAZOLIC COMPOUNDS
JPS5543011A (en) * 1978-09-20 1980-03-26 Shionogi & Co Ltd 7-halothiazolylalkoxyiminoacetamido-3-cephem compound
GR78221B (en) * 1980-02-01 1984-09-26 Ciba Geigy Ag

Also Published As

Publication number Publication date
ES516593A0 (en) 1983-11-16
ES516592A0 (en) 1983-08-01
ES8401078A1 (en) 1983-11-16
GB2111043A (en) 1983-06-29
ES8401080A1 (en) 1983-11-16
HU185985B (en) 1985-04-28
PT74119B (en) 1983-12-19
ES8303424A1 (en) 1983-02-01
GR76967B (en) 1984-09-04
NO814232L (en) 1982-06-14
IE52008B1 (en) 1987-05-13
KR830007683A (en) 1983-11-04
FI813946A7 (en) 1982-06-13
ES8401079A1 (en) 1983-11-16
JPS57123190A (en) 1982-07-31
IL64506A (en) 1985-05-31
AU7846681A (en) 1982-06-17
NZ199255A (en) 1985-08-30
EP0054512A2 (en) 1982-06-23
ZA818622B (en) 1982-10-27
DD208155A5 (en) 1984-03-28
ES507907A0 (en) 1983-02-01
ES516594A0 (en) 1983-11-16
JPH0314038B2 (en) 1991-02-25
PT74119A (en) 1982-01-01
ES516591A0 (en) 1983-11-16
EP0054512A3 (en) 1983-08-03
DK550081A (en) 1982-06-13
FI813946L (en) 1982-06-13
IL64506A0 (en) 1982-03-31
GB2111043B (en) 1985-02-06
ES516590A0 (en) 1983-11-16
ES8307820A1 (en) 1983-08-01
AR231984A1 (en) 1985-04-30
ES8401077A1 (en) 1983-11-16

Similar Documents

Publication Publication Date Title
PT87474A (en) PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOUNDS WHICH CONTAIN ESTER 1-ACETOXY-ETHYLIC OF CEFUROXIME
HUT65278A (en) Process for producing pyrido-, pyrrolo-, thiazino-, oxazino- and pyrazino-benzazepine derivatives and pharmaceutical preparations containing them
IE782070L (en) Azabicyclo (3.2.0) hept-2-ene carboxylic acid derivatives
IE810348L (en) Cephalosporins.
IE812915L (en) ESTERS OF 7ß-SUBSTITUTED CEPH-3-EM-4-CARBOXYLIC ACIDS
IL57392A (en) 7-(2-(2-aminothiazolyl)-(2-methoxyimino))acetamido-3-(di-and tetrahydrotriazinyl)thiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
AU3003189A (en) 7(2-(2-aminothiazol-4-yl)-2-hydroxyimino-acetamido)-3- methoxymethyl-3-cephem-4-carboxylate ester derivatives
IE831648L (en) Cephalosporin compounds
IL78301A (en) 7-beta-(2-(2-amino-4-thiazolyl)-2-alkenoylamino)-3-cephem-4-carboxylic acid esters,processes for the preparation thereof and anti-bacterial compositions containing the same
AU6677981A (en) 7b-(2-)2-amino-4-huazolyl d-2-methaoryminoaretamido-3-cephem- 4-carboxylic acid pivaloyloxymethyl ester
IE811811L (en) Cephalosporins
FI853050A7 (en) Process for the preparation of pharmaceutically active quinolone carboxylic acid derivatives.
IL66776A (en) 2beta-substituted-2alpha-methyl-(5r)-penam-3alpha-carboxylic acid 1,1-dioxides,their preparation and pharmaceutical compositions containing them
AU4605279A (en) Oxime derivatives of 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanic acid, their process of preparation and pharmaceutical compositions containing them
JPS5246093A (en) 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof
IE802552L (en) Cephalosporins.
IE820914L (en) Controlling ureaplasma infections
FR2612173B1 (en) PROCESS FOR THE PREPARATION OF HIGH PURITY MANGANESE COMPOUNDS
AU3620089A (en) New process for the preparation of n-(23-vinblastinoyl) derivatives of 1-amino-methyl-phosphonic acid
HUT42492A (en) Process for producing cepheme-carboxylic acid derivatives and pharmaceutical compositions containing them as active agents
IE811951L (en) Oxazaphosphorins
IE820912L (en) Controlling ureaplasma infections
EP0128027A3 (en) Cephalosporin esters, their production and use
AU7993982A (en) Tetra-peptide
PL240238A1 (en) Process for preparing 6-alpha-methoxy-6-beta/2-(2-methylphenoxycarbonyl)-2-(thien-3-yl)-acetamido/penicillanic acid