IE812147L - Combination compositions - Google Patents
Combination compositionsInfo
- Publication number
- IE812147L IE812147L IE812147A IE214781A IE812147L IE 812147 L IE812147 L IE 812147L IE 812147 A IE812147 A IE 812147A IE 214781 A IE214781 A IE 214781A IE 812147 L IE812147 L IE 812147L
- Authority
- IE
- Ireland
- Prior art keywords
- antibiotic
- amino
- physiologically acceptable
- combination compositions
- combination
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- JBDGDEWWOUBZPM-UHFFFAOYSA-N 4-[(2-amino-3,5-dibromophenyl)methylamino]-1-cyclohexanol Chemical compound NC1=C(Br)C=C(Br)C=C1CNC1CCC(O)CC1 JBDGDEWWOUBZPM-UHFFFAOYSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004100 Oxytetracycline Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 abstract 1
- 229960005174 ambroxol Drugs 0.000 abstract 1
- 229960003022 amoxicillin Drugs 0.000 abstract 1
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 abstract 1
- 229960000723 ampicillin Drugs 0.000 abstract 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 229940106164 cephalexin Drugs 0.000 abstract 1
- ZAIPMKNFIOOWCQ-UEKVPHQBSA-N cephalexin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C)C(O)=O)=CC=CC=C1 ZAIPMKNFIOOWCQ-UEKVPHQBSA-N 0.000 abstract 1
- 229960005091 chloramphenicol Drugs 0.000 abstract 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 abstract 1
- 229960003722 doxycycline Drugs 0.000 abstract 1
- XQTWDDCIUJNLTR-CVHRZJFOSA-N doxycycline monohydrate Chemical compound O.O=C1C2=C(O)C=CC=C2[C@H](C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]1[C@H]2O XQTWDDCIUJNLTR-CVHRZJFOSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229960003276 erythromycin Drugs 0.000 abstract 1
- 229960000625 oxytetracycline Drugs 0.000 abstract 1
- IWVCMVBTMGNXQD-PXOLEDIWSA-N oxytetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3[C@H](O)[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-PXOLEDIWSA-N 0.000 abstract 1
- 235000019366 oxytetracycline Nutrition 0.000 abstract 1
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Pharmaceutical compositions comprising, in combination, an antibiotic or a physiologically acceptable salt thereof and trans-4-[(2-amino-3,5- dibromo-benzyl)-amino]cyclohexanol or a physiologically acceptable acid addition salt thereof (e.g. the hydrochloride, ambroxol), optionally in association with a pharmaceutical carrier or excipient for use in combating bacterial infections of the respiratory tract. The antibiotic is preferably erythromycin, doxycycline, oxytetracycline, chloramphenicol, cephalexin, ampicillin or amoxycillin.
[GB2083749A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3034975A DE3034975C2 (en) | 1980-09-17 | 1980-09-17 | Drug combination used to treat infectious respiratory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE812147L true IE812147L (en) | 1982-03-17 |
| IE51517B1 IE51517B1 (en) | 1987-01-07 |
Family
ID=6112126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2147/81A IE51517B1 (en) | 1980-09-17 | 1981-09-16 | Drug combination for the treatment of infectious diseases of the respiratory tract |
Country Status (8)
| Country | Link |
|---|---|
| CH (1) | CH648209A5 (en) |
| DE (1) | DE3034975C2 (en) |
| FR (1) | FR2493145A1 (en) |
| GB (1) | GB2083749B (en) |
| HK (1) | HK20785A (en) |
| IE (1) | IE51517B1 (en) |
| SG (1) | SG785G (en) |
| ZA (1) | ZA816417B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5888311A (en) * | 1981-11-20 | 1983-05-26 | Teijin Ltd | Remedy for respiratory disease |
| AUPN115095A0 (en) * | 1995-02-15 | 1995-03-09 | Butt, Henry Lawrence | Analysis of and compositions and methods for the treatment of disease |
| DE19933148A1 (en) | 1999-07-20 | 2001-01-25 | Boehringer Ingelheim Int | Lozenge containing ambroxol |
| US20030166732A1 (en) * | 2002-02-27 | 2003-09-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity |
| DE10208313A1 (en) * | 2002-02-27 | 2003-09-11 | Boehringer Ingelheim Pharma | Ambroxol for the treatment of painful conditions in the mouth and throat |
| CN1323662C (en) * | 2004-06-18 | 2007-07-04 | 江苏恒瑞医药股份有限公司 | Pharmaceutical composition containing ambroxol and erdosteine or acetylcysteine and application thereof |
| CN100434078C (en) * | 2005-05-16 | 2008-11-19 | 天津药物研究院 | Ambroxol hydrochloride compound slow-release tablet and its preparing method |
| RU2749902C2 (en) * | 2018-10-31 | 2021-06-18 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Pharmaceutical composition for treatment of infectious and inflammatory diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795585A (en) * | 1972-02-17 | 1973-08-16 | Thomae Gmbh Dr K | NEW PULMONARY MEDICINE |
-
1980
- 1980-09-17 DE DE3034975A patent/DE3034975C2/en not_active Expired
-
1981
- 1981-09-15 CH CH5962/81A patent/CH648209A5/en not_active IP Right Cessation
- 1981-09-16 GB GB8127983A patent/GB2083749B/en not_active Expired
- 1981-09-16 IE IE2147/81A patent/IE51517B1/en not_active IP Right Cessation
- 1981-09-16 ZA ZA816417A patent/ZA816417B/en unknown
- 1981-09-17 FR FR8117603A patent/FR2493145A1/en active Granted
-
1985
- 1985-01-04 SG SG7/85A patent/SG785G/en unknown
- 1985-03-21 HK HK207/85A patent/HK20785A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SG785G (en) | 1985-06-14 |
| GB2083749B (en) | 1984-05-23 |
| FR2493145A1 (en) | 1982-05-07 |
| IE51517B1 (en) | 1987-01-07 |
| FR2493145B1 (en) | 1984-12-21 |
| HK20785A (en) | 1985-03-29 |
| DE3034975A1 (en) | 1982-04-29 |
| CH648209A5 (en) | 1985-03-15 |
| ZA816417B (en) | 1983-05-25 |
| DE3034975C2 (en) | 1986-11-27 |
| GB2083749A (en) | 1982-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK9A | Patent expired |