IE43106L - Mocimycin derivatives - Google Patents
Mocimycin derivativesInfo
- Publication number
- IE43106L IE43106L IE761021A IE102176A IE43106L IE 43106 L IE43106 L IE 43106L IE 761021 A IE761021 A IE 761021A IE 102176 A IE102176 A IE 102176A IE 43106 L IE43106 L IE 43106L
- Authority
- IE
- Ireland
- Prior art keywords
- antibiotic
- dihydromocimycin
- mocimycin
- dehydrogenation
- properties
- Prior art date
Links
- HMSYAPGFKGSXAJ-PAHGNTJYSA-N Mocimycin Chemical class C(/[C@H]1O[C@H]([C@H]([C@H]1O)O)[C@H](C)[C@H](OC)C(/C)=C/C=C/CNC(=O)[C@@H](CC)[C@]1(O)[C@@H]([C@H](O)C(C)(C)[C@H](\C=C\C=C/C)O1)O)=C\C=C\C=C(/C)C(=O)C1=C(O)NC=CC1=O HMSYAPGFKGSXAJ-PAHGNTJYSA-N 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 3
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 2
- JPJALAQPGMAKDF-UHFFFAOYSA-N selenium dioxide Chemical compound O=[Se]=O JPJALAQPGMAKDF-UHFFFAOYSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000187409 Streptomyces ramocissimus Species 0.000 abstract 1
- 241000589886 Treponema Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000001848 dysentery Diseases 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229950008095 mocimycin Drugs 0.000 abstract 1
- HMSYAPGFKGSXAJ-KNHRXMRASA-N mocimycin Natural products C([C@H]1O[C@H]([C@H]([C@H]1O)O)[C@H](C)[C@H](OC)C(C)=CC=CCNC(=O)[C@@H](CC)[C@]1(O)[C@@H]([C@H](O)C(C)(C)[C@H](C=CC=CC)O1)O)=CC=CC=C(C)C(=O)C1=C(O)NC=CC1=O HMSYAPGFKGSXAJ-KNHRXMRASA-N 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000012153 swine disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Molecular Biology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
A new antibiotic (now called dihydromocimycin) being a yellow, salt-forming weak acid and its non-toxic, pharmaceutically acceptable salts produced by the microorganism Streptomyces ramocissimus or suitable mutants thereof. The antibiotic has antibacterial properties and has been found to be effective against Treponema dysentery, one of the most common swine diseases. Dihydromocimycin may also be converted into mocimycin, which is an antibiotic which possesses interesting growthpromoting properties when added to animal feed, by a dehydrogenation agent. The dehydrogenation may be carried out with selenium dioxide, preferably in the presence of an organic solvent.
[CA1070630A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB20926/75A GB1545474A (en) | 1975-05-16 | 1975-05-16 | Mocimycin derivatives |
| GB3064675 | 1975-07-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE43106L true IE43106L (en) | 1976-11-16 |
| IE43106B1 IE43106B1 (en) | 1980-12-17 |
Family
ID=26254986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1021/76A IE43106B1 (en) | 1975-05-16 | 1976-05-13 | Mocimycin derivatives |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS52277A (en) |
| AU (1) | AU499529B2 (en) |
| CA (1) | CA1070630A (en) |
| CH (1) | CH630411A5 (en) |
| DE (1) | DE2658977C3 (en) |
| DK (1) | DK143606C (en) |
| FI (1) | FI54308C (en) |
| FR (1) | FR2310760A1 (en) |
| IE (1) | IE43106B1 (en) |
| IT (1) | IT1070097B (en) |
| LU (1) | LU74958A1 (en) |
| NL (1) | NL162136C (en) |
| NZ (1) | NZ180860A (en) |
| SE (2) | SE435512B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55142039A (en) * | 1979-04-23 | 1980-11-06 | Tokuyama Soda Co Ltd | Polypropylene composition |
| JPS621987A (en) * | 1985-06-27 | 1987-01-07 | 積水化学工業株式会社 | Window frame |
| JPS621988A (en) * | 1985-06-27 | 1987-01-07 | 積水化学工業株式会社 | Window frame |
| JPH0815434B2 (en) * | 1987-02-03 | 1996-02-21 | 三菱化学株式会社 | Novel antibiotic vermisporin and method for producing the same |
| JPH02128783U (en) * | 1989-03-31 | 1990-10-24 |
-
1976
- 1976-05-13 NZ NZ180860A patent/NZ180860A/en unknown
- 1976-05-13 AU AU13930/76A patent/AU499529B2/en not_active Expired
- 1976-05-13 NL NL7605093.A patent/NL162136C/en not_active IP Right Cessation
- 1976-05-13 DK DK215176A patent/DK143606C/en not_active IP Right Cessation
- 1976-05-13 IE IE1021/76A patent/IE43106B1/en unknown
- 1976-05-14 FI FI761380A patent/FI54308C/en not_active IP Right Cessation
- 1976-05-14 JP JP51055985A patent/JPS52277A/en active Granted
- 1976-05-14 CH CH610676A patent/CH630411A5/en not_active IP Right Cessation
- 1976-05-14 SE SE7605536A patent/SE435512B/en not_active IP Right Cessation
- 1976-05-14 FR FR7614694A patent/FR2310760A1/en active Granted
- 1976-05-14 CA CA252,534A patent/CA1070630A/en not_active Expired
- 1976-05-14 DE DE2658977A patent/DE2658977C3/en not_active Expired
- 1976-05-14 LU LU74958A patent/LU74958A1/xx unknown
- 1976-05-14 IT IT68189/76A patent/IT1070097B/en active
-
1980
- 1980-08-07 SE SE8005599A patent/SE8005599L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ180860A (en) | 1978-04-03 |
| DE2658977A1 (en) | 1977-05-05 |
| SE435512B (en) | 1984-10-01 |
| DK215176A (en) | 1976-11-17 |
| JPS52277A (en) | 1977-01-05 |
| SE8005599L (en) | 1980-08-07 |
| NL7605093A (en) | 1976-11-18 |
| DK143606C (en) | 1982-02-22 |
| IE43106B1 (en) | 1980-12-17 |
| DE2621615A1 (en) | 1976-11-25 |
| FR2310760B1 (en) | 1978-11-17 |
| JPS5522479B2 (en) | 1980-06-17 |
| SE7605536L (en) | 1976-11-17 |
| IT1070097B (en) | 1985-03-25 |
| AU499529B2 (en) | 1979-04-26 |
| FI761380A7 (en) | 1976-11-17 |
| DE2621615B2 (en) | 1977-07-07 |
| CA1070630A (en) | 1980-01-29 |
| DK143606B (en) | 1981-09-14 |
| DE2658977B2 (en) | 1978-01-26 |
| NL162136C (en) | 1980-04-15 |
| FI54308C (en) | 1978-11-10 |
| NL162136B (en) | 1979-11-15 |
| DE2658977C3 (en) | 1978-09-28 |
| AU1393076A (en) | 1977-11-17 |
| LU74958A1 (en) | 1977-01-17 |
| FI54308B (en) | 1978-07-31 |
| CH630411A5 (en) | 1982-06-15 |
| FR2310760A1 (en) | 1976-12-10 |
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