IE42666L - Deoxyclavulanic acid and deoxyisoclavulanic acid and¹derivatives thereof - Google Patents
Deoxyclavulanic acid and deoxyisoclavulanic acid and¹derivatives thereofInfo
- Publication number
- IE42666L IE42666L IE760628A IE62876A IE42666L IE 42666 L IE42666 L IE 42666L IE 760628 A IE760628 A IE 760628A IE 62876 A IE62876 A IE 62876A IE 42666 L IE42666 L IE 42666L
- Authority
- IE
- Ireland
- Prior art keywords
- acid
- deoxyisoclavulanic
- deoxyclavulanic
- formula
- compounds
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 229930186147 Cephalosporin Chemical class 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical class N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D503/02—Preparation
- C07D503/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Cephalosporin Compounds (AREA)
Abstract
A N T I B I O T I C S The compounds of the formula: and salts and esters thereof are useful agents for the treatment of bacterial infections either alone or in combination with a penicillin or cephalosporin derivative. The proceeding compounds may be prepared by the hydrogenation of a compound of the formula: wherein R is a hydrogen atom or an acyl group or a salt or ester thereof.
[CA1074802A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB15209/75A GB1545467A (en) | 1975-04-14 | 1975-04-14 | Deoxyclavulanic acid and deoxyisoclavulanic acid and derivatives thereof |
| GB3967175 | 1975-09-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42666L true IE42666L (en) | 1976-10-14 |
| IE42666B1 IE42666B1 (en) | 1980-09-24 |
Family
ID=26251136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE628/76A IE42666B1 (en) | 1975-04-14 | 1976-03-25 | Deoxyclavulanic acid and deoxyisoclavulanic acid and derivatives thereof |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS51127093A (en) |
| AR (1) | AR208773A1 (en) |
| AT (1) | AT342199B (en) |
| AU (1) | AU497577B2 (en) |
| CA (1) | CA1074802A (en) |
| CH (1) | CH602742A5 (en) |
| DE (1) | DE2616088A1 (en) |
| DK (1) | DK144066C (en) |
| ES (1) | ES446468A1 (en) |
| FI (1) | FI760946A7 (en) |
| FR (1) | FR2336130A1 (en) |
| GR (1) | GR58256B (en) |
| HU (1) | HU175444B (en) |
| IE (1) | IE42666B1 (en) |
| IL (1) | IL49279A (en) |
| LU (1) | LU74749A1 (en) |
| MX (1) | MX3453E (en) |
| NL (1) | NL7603840A (en) |
| NO (1) | NO761241L (en) |
| PT (1) | PT64897B (en) |
| SE (1) | SE427037B (en) |
| YU (1) | YU69476A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2740526A1 (en) * | 1976-09-09 | 1978-03-16 | Glaxo Lab Ltd | CLAVULANIC ACID COMPONENTS AND THEIR PRODUCTION |
| IT1091113B (en) * | 1976-10-25 | 1985-06-26 | Glaxo Lab Ltd | THERAPEUTIC COMPOSITIONS BASED ON N-ACYL-DERIVATIVES OF CLAVULANIC ACID AND PROCEDURE TO PRODUCE THEM |
| GB9007143D0 (en) * | 1990-03-30 | 1990-05-30 | Beecham Group Plc | Veterinary composition |
-
1976
- 1976-03-12 GR GR50291A patent/GR58256B/en unknown
- 1976-03-12 PT PT64897A patent/PT64897B/en unknown
- 1976-03-18 YU YU00694/76A patent/YU69476A/en unknown
- 1976-03-24 IL IL49279A patent/IL49279A/en unknown
- 1976-03-24 AT AT215576A patent/AT342199B/en not_active IP Right Cessation
- 1976-03-25 IE IE628/76A patent/IE42666B1/en unknown
- 1976-03-29 FR FR7609025A patent/FR2336130A1/en active Granted
- 1976-03-29 ES ES446468A patent/ES446468A1/en not_active Expired
- 1976-03-31 AR AR262754A patent/AR208773A1/en active
- 1976-03-31 DK DK156576A patent/DK144066C/en not_active IP Right Cessation
- 1976-04-05 MX MX000141U patent/MX3453E/en unknown
- 1976-04-07 FI FI760946A patent/FI760946A7/fi not_active Application Discontinuation
- 1976-04-09 NO NO761241A patent/NO761241L/no unknown
- 1976-04-12 NL NL7603840A patent/NL7603840A/en not_active Application Discontinuation
- 1976-04-12 SE SE7604287A patent/SE427037B/en unknown
- 1976-04-12 LU LU74749A patent/LU74749A1/xx unknown
- 1976-04-13 DE DE19762616088 patent/DE2616088A1/en not_active Withdrawn
- 1976-04-13 CH CH470276A patent/CH602742A5/xx not_active IP Right Cessation
- 1976-04-13 CA CA250,165A patent/CA1074802A/en not_active Expired
- 1976-04-13 JP JP51042313A patent/JPS51127093A/en active Pending
- 1976-04-14 AU AU13020/76A patent/AU497577B2/en not_active Expired
- 1976-04-14 HU HU76BE1258A patent/HU175444B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2616088A1 (en) | 1976-10-28 |
| FR2336130B1 (en) | 1979-06-22 |
| FR2336130A1 (en) | 1977-07-22 |
| IL49279A0 (en) | 1976-06-30 |
| MX3453E (en) | 1980-12-03 |
| NO761241L (en) | 1976-10-15 |
| ES446468A1 (en) | 1977-11-01 |
| DK144066C (en) | 1982-05-10 |
| JPS51127093A (en) | 1976-11-05 |
| CA1074802A (en) | 1980-04-01 |
| AU1302076A (en) | 1977-10-20 |
| DK144066B (en) | 1981-11-30 |
| AT342199B (en) | 1978-03-28 |
| SE427037B (en) | 1983-02-28 |
| CH602742A5 (en) | 1978-07-31 |
| ATA215576A (en) | 1977-07-15 |
| AR208773A1 (en) | 1977-02-28 |
| LU74749A1 (en) | 1976-11-11 |
| HU175444B (en) | 1980-08-28 |
| NL7603840A (en) | 1976-10-18 |
| IE42666B1 (en) | 1980-09-24 |
| DK156576A (en) | 1976-10-15 |
| PT64897B (en) | 1977-08-18 |
| SE7604287L (en) | 1976-10-15 |
| GR58256B (en) | 1977-09-15 |
| IL49279A (en) | 1979-05-31 |
| YU69476A (en) | 1982-05-31 |
| AU497577B2 (en) | 1978-12-21 |
| PT64897A (en) | 1976-04-01 |
| FI760946A7 (en) | 1976-10-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE782070L (en) | Azabicyclo (3.2.0) hept-2-ene carboxylic acid derivatives | |
| MY131501A (en) | Process for the prepration of clavulanic acid | |
| IE45003L (en) | Oxiranylmethyltetrahydropyran derivatives | |
| IE45015L (en) | Cephalosporin derivatives. | |
| MY102919A (en) | Pleuromutilin derivatives process for their preparation and their use. | |
| IE43840L (en) | Clavulanic acid derivatives | |
| IE780899L (en) | Azetidinopyrrole derivatives | |
| IE782546L (en) | Amino-thiazolyl cephalosporins | |
| GB1427139A (en) | Penicillins | |
| IE44759L (en) | 1-aza-4-oxabicyclo [3,2,0] heptane derivatives | |
| IE42666L (en) | Deoxyclavulanic acid and deoxyisoclavulanic acid and¹derivatives thereof | |
| IE42957L (en) | Rosamicin (antibiotic 67-694) derivatives. | |
| IE44295L (en) | Preparation of clavulanic acid | |
| ES442217A1 (en) | 1,4-Dihydro-4-oxo-pyridylacetamido cephalosporins and their utilization as medicinal agents for combating bacterial infections | |
| GB1347598A (en) | Lincomycin derivatives and the manufacture thereof | |
| GB1501643A (en) | Antibacterial substituted azetidinones | |
| IE35032B1 (en) | Phenyl-azolyl-fatty acid derivatives,process for their production and their use as medicines | |
| IE771799L (en) | Cephalosporins. | |
| GB1507723A (en) | Acyloxymethyl cephalosporin esters | |
| IE46100L (en) | Clavulanic acid derivatives | |
| IE40528B1 (en) | Cephalosporin derivatives and the preparation thereof | |
| GB1410872A (en) | Tetrahydropyran and tetrahydrothiapyran derivatives | |
| IE42992L (en) | PYRIMIDO [1,2-a] QUINOLINE DERIVATIVES | |
| ES8104285A1 (en) | Clavulanic acid derivatives, their preparation and use in pharmaceutical compositions. | |
| IE782539L (en) | Penicillin derivatives |