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ID26665A - Antagonis vla-4 - Google Patents

Antagonis vla-4

Info

Publication number
ID26665A
ID26665A IDW20001404A ID20001404A ID26665A ID 26665 A ID26665 A ID 26665A ID W20001404 A IDW20001404 A ID W20001404A ID 20001404 A ID20001404 A ID 20001404A ID 26665 A ID26665 A ID 26665A
Authority
ID
Indonesia
Prior art keywords
vla
antagonists
Prior art date
Application number
IDW20001404A
Other languages
English (en)
Indonesian (id)
Inventor
Sompong Wattanasin
Peter Joseph Von Matt
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ID26665A publication Critical patent/ID26665A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IDW20001404A 1998-01-23 1999-01-21 Antagonis vla-4 ID26665A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1233698A 1998-01-23 1998-01-23
US11072398P 1998-12-03 1998-12-03

Publications (1)

Publication Number Publication Date
ID26665A true ID26665A (id) 2001-01-25

Family

ID=26683440

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001404A ID26665A (id) 1998-01-23 1999-01-21 Antagonis vla-4

Country Status (13)

Country Link
EP (1) EP1049665A1 (fr)
JP (1) JP4564654B2 (fr)
KR (1) KR20010034317A (fr)
CN (1) CN1294576A (fr)
AU (1) AU746174B2 (fr)
BR (1) BR9907733A (fr)
CA (1) CA2318639A1 (fr)
EE (1) EE200000428A (fr)
HU (1) HUP0100336A3 (fr)
ID (1) ID26665A (fr)
IL (1) IL137329A0 (fr)
NO (1) NO20003694L (fr)
WO (1) WO1999037605A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043372A1 (fr) * 1999-01-22 2000-07-27 Elan Pharmaceuticals, Inc. Derives d'acyle utiles pour traiter des affections associees a vla-4
ATE455106T1 (de) 1999-01-22 2010-01-15 Elan Pharm Inc Acyl derivate zur behandlung von krankheiten die in zusammenhang mit vla-4 stehen
US6436904B1 (en) 1999-01-25 2002-08-20 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
WO2000051974A1 (fr) 1999-03-01 2000-09-08 Elan Pharmaceuticals, Inc. Derives de l'acide alpha-aminoacetique antagonistes du recepteur alpha 4 beta 7
CA2388686A1 (fr) * 1999-12-07 2001-06-14 Sompong Wattanasin Antagonistes de l'integrine vla-4
EP1244656A1 (fr) * 1999-12-28 2002-10-02 Pfizer Products Inc. Inhibiteurs non peptidyle de liaison cellulaire dependant de vla-4 utiles pour le traitement de maladies inflammatoires, auto-immunes et respiratoires
DE10019755A1 (de) * 2000-04-20 2001-11-08 Bayer Ag Neue Aminoaryl/cycloalkylcarbonsäuren als Integrinantagonisten
GB2367816A (en) 2000-10-09 2002-04-17 Bayer Ag Urea- and thiourea-containing derivatives of beta-amino acids
GB2369357A (en) * 2000-10-09 2002-05-29 Bayer Ag Aliphatic, cyclic amino carboxylic acids as integrin antagonists
GB2377933A (en) 2001-07-06 2003-01-29 Bayer Ag Succinic acid derivatives useful as integrin antagonists
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
TW200610754A (en) * 2004-06-14 2006-04-01 Daiichi Seiyaku Co Vla-4 inhibitor
GB0523576D0 (en) * 2005-11-18 2005-12-28 Theradeas Ltd Drug composition and its use in therapy
JP5135235B2 (ja) 2006-02-27 2013-02-06 エラン ファーマシューティカルズ,インコーポレイテッド Val−4によって媒介される白血球の接着を阻害するピリミジニルスルホンアミド化合物
CA2714335A1 (fr) 2007-02-20 2008-08-28 Merrimack Pharmaceuticals, Inc. Methodes de traitement de la sclerose en plaques par administration d'une alpha-foetoproteine combinee a un antagoniste de l'integrine
NZ589086A (en) 2008-04-11 2012-09-28 Merrimack Pharmaceuticals Inc Human serum albumin (HSA) linkers and conjugates thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6306840B1 (en) * 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
CZ20002342A3 (cs) * 1997-12-23 2001-11-14 Aventis Pharma Limited Substituované ß-alaniny

Also Published As

Publication number Publication date
AU2829299A (en) 1999-08-09
KR20010034317A (ko) 2001-04-25
CA2318639A1 (fr) 1999-07-29
WO1999037605A1 (fr) 1999-07-29
CN1294576A (zh) 2001-05-09
AU746174B2 (en) 2002-04-18
HUP0100336A3 (en) 2002-11-28
EP1049665A1 (fr) 2000-11-08
IL137329A0 (en) 2001-07-24
NO20003694D0 (no) 2000-07-19
NO20003694L (no) 2000-09-20
JP4564654B2 (ja) 2010-10-20
JP2002501039A (ja) 2002-01-15
HUP0100336A2 (hu) 2001-07-30
EE200000428A (et) 2001-12-17
BR9907733A (pt) 2000-10-17

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