HUT61566A - Process for producing 2,2'-o-cyclonucleosides, nucleosides and their analogous compounds - Google Patents
Process for producing 2,2'-o-cyclonucleosides, nucleosides and their analogous compoundsInfo
- Publication number
- HUT61566A HUT61566A HU9202906A HU290692A HUT61566A HU T61566 A HUT61566 A HU T61566A HU 9202906 A HU9202906 A HU 9202906A HU 290692 A HU290692 A HU 290692A HU T61566 A HUT61566 A HU T61566A
- Authority
- HU
- Hungary
- Prior art keywords
- producing
- cyclonucleosides
- nucleosides
- nucleoside
- analogous compounds
- Prior art date
Links
- 239000002777 nucleoside Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 125000003835 nucleoside group Chemical group 0.000 title 1
- -1 cytarabine Chemical class 0.000 abstract 3
- UHDGCWIWMRVCDJ-CCXZUQQUSA-N Cytarabine Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-CCXZUQQUSA-N 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 229960000684 cytarabine Drugs 0.000 abstract 2
- 230000000118 anti-neoplastic effect Effects 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 239000003125 aqueous solvent Substances 0.000 abstract 1
- 229940127073 nucleoside analogue Drugs 0.000 abstract 1
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2012094 CA2012094C (en) | 1990-03-13 | 1990-03-13 | Process for producing cytarabine and analogues thereof |
| CA 2012093 CA2012093C (en) | 1990-03-13 | 1990-03-13 | Process for producing 2,2'-cyclocytidine and analogues thereof |
| PCT/CA1991/000077 WO1991013900A1 (en) | 1990-03-13 | 1991-03-13 | Process for producing 2,2'-o-cyclonucleosides, nucleosides, and analogs thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9202906D0 HU9202906D0 (en) | 1992-11-30 |
| HUT61566A true HUT61566A (en) | 1993-01-28 |
Family
ID=25674007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9202906A HUT61566A (en) | 1990-03-13 | 1991-03-13 | Process for producing 2,2'-o-cyclonucleosides, nucleosides and their analogous compounds |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5610292A (hu) |
| EP (1) | EP0521923B1 (hu) |
| AT (1) | ATE119541T1 (hu) |
| AU (1) | AU7473791A (hu) |
| BR (1) | BR9106158A (hu) |
| DE (1) | DE69108014T2 (hu) |
| HU (1) | HUT61566A (hu) |
| WO (1) | WO1991013900A1 (hu) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0767657A4 (en) * | 1994-06-22 | 1999-01-20 | Nexstar Pharmaceuticals Inc | NOVEL PROCESS FOR THE PRODUCTION OF KNOWN AND NEW NUCLEOSIDES, MODIFIED IN THE 2 'POSITION BY INTRAMOLECULAR NUCLEOPHILIC DISPLACEMENT |
| IT1277425B1 (it) | 1995-08-03 | 1997-11-10 | Pro Bio Sint Srl | Metodo per la preparazione della 1-b-d-arabinofuranosilcitosina |
| CA2277159A1 (en) | 1997-01-08 | 1998-07-16 | Wolfgang Pieken | Bioconjugation of macromolecules |
| US7427678B2 (en) | 1998-01-08 | 2008-09-23 | Sigma-Aldrich Co. | Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method |
| EP1186612B1 (en) * | 2000-04-13 | 2006-11-29 | Mitsui Chemicals, Inc. | Process for the preparation of cytidine derivatives |
| ATE445838T1 (de) | 2001-07-25 | 2009-10-15 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| AU2003210629A1 (en) | 2002-01-23 | 2003-09-02 | Proligo, Llc | Methods for the integrated synthesis and purification of oligonucleotides |
| WO2004058794A1 (en) | 2002-12-31 | 2004-07-15 | Proligo Llc | Methods and compositions for the tandem synthesis of two or more oligonuleotides on the same solid support |
| EP1668023A1 (de) * | 2003-09-12 | 2006-06-14 | Max-Delbrück-Centrum Für Molekulare Medizin | B-l-nucleoside und ihre verwendung als pharmazeutische mittel zur behandlung viraler erkrankungen |
| CN1300326C (zh) * | 2004-12-22 | 2007-02-14 | 华南理工大学 | 酶催化制备阿糖胞苷酯的方法 |
| CA2789097C (en) | 2005-04-28 | 2017-02-21 | Proteus Digital Health, Inc. | Pharma-informatics system |
| JP2010503710A (ja) | 2006-09-18 | 2010-02-04 | ラプトール ファーマシューティカル インコーポレイテッド | 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置 |
| US8404830B2 (en) | 2007-07-17 | 2013-03-26 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| EP2265274B1 (en) | 2008-03-03 | 2018-11-21 | Tosk, Inc. | Methotrexate adjuvants to reduce toxicity and methods for using the same |
| NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| MX2012011771A (es) | 2010-04-12 | 2012-12-17 | Somalogic Inc | Aptameros para beta-ngf y su uso en el tratamiento de enfermedades y trastornos mediados por beta-ngf. |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| JP7008405B2 (ja) | 2013-11-21 | 2022-01-25 | ソマロジック・インコーポレーテッド | シチジン－５－カルボキサミド修飾ヌクレオチド組成物及びそれに関連する方法 |
| US11446303B2 (en) | 2019-06-21 | 2022-09-20 | Tosk, Inc. | Uridine phosphorylase (UPase) inhibitors for treatment of liver conditions |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4652554A (en) * | 1982-02-22 | 1987-03-24 | St. Jude Children's Research Hospital | Nitro-substituted 1-β-D-arabinofuranosylcytosines |
| ATE125265T1 (de) * | 1990-03-13 | 1995-08-15 | Acic Canada Inc | 2,3'-o-cyclocytidine und verfahren zu deren herstellung. |
-
1991
- 1991-03-13 DE DE69108014T patent/DE69108014T2/de not_active Expired - Fee Related
- 1991-03-13 HU HU9202906A patent/HUT61566A/hu unknown
- 1991-03-13 AU AU74737/91A patent/AU7473791A/en not_active Abandoned
- 1991-03-13 BR BR919106158A patent/BR9106158A/pt not_active Application Discontinuation
- 1991-03-13 WO PCT/CA1991/000077 patent/WO1991013900A1/en not_active Ceased
- 1991-03-13 AT AT91906244T patent/ATE119541T1/de not_active IP Right Cessation
- 1991-03-13 EP EP91906244A patent/EP0521923B1/en not_active Expired - Lifetime
-
1994
- 1994-09-27 US US08/313,579 patent/US5610292A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE119541T1 (de) | 1995-03-15 |
| EP0521923B1 (en) | 1995-03-08 |
| WO1991013900A1 (en) | 1991-09-19 |
| AU7473791A (en) | 1991-10-10 |
| DE69108014D1 (de) | 1995-04-13 |
| BR9106158A (pt) | 1993-03-16 |
| EP0521923A1 (en) | 1993-01-13 |
| US5610292A (en) | 1997-03-11 |
| DE69108014T2 (de) | 1995-07-06 |
| HU9202906D0 (en) | 1992-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DFD9 | Temporary protection cancelled due to non-payment of fee |