HUS2500017I1 - Szöveti faktor bioszintézis út elleni ellenanyagok - Google Patents
Szöveti faktor bioszintézis út elleni ellenanyagokInfo
- Publication number
- HUS2500017I1 HUS2500017I1 HUS2500017C HUS2500017C HUS2500017I1 HU S2500017 I1 HUS2500017 I1 HU S2500017I1 HU S2500017 C HUS2500017 C HU S2500017C HU S2500017 C HUS2500017 C HU S2500017C HU S2500017 I1 HUS2500017 I1 HU S2500017I1
- Authority
- HU
- Hungary
- Prior art keywords
- antibodies against
- tissue factor
- pathway inhibitor
- against tissue
- factor pathway
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08172520 | 2008-12-22 | ||
| EP09793543.1A EP2379600B2 (en) | 2008-12-22 | 2009-12-18 | Antibodies against tissue factor pathway inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUS2500017I1 true HUS2500017I1 (hu) | 2025-04-28 |
Family
ID=40639722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUS2500017C HUS2500017I1 (hu) | 2008-12-22 | 2025-03-25 | Szöveti faktor bioszintézis út elleni ellenanyagok |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US8361469B2 (hu) |
| EP (3) | EP2746294A3 (hu) |
| JP (2) | JP5714505B2 (hu) |
| KR (2) | KR101745394B1 (hu) |
| CN (1) | CN102325795B (hu) |
| AU (1) | AU2009331570C1 (hu) |
| BR (1) | BRPI0924058B1 (hu) |
| CA (1) | CA2745317C (hu) |
| DK (1) | DK2379600T4 (hu) |
| ES (1) | ES2458665T5 (hu) |
| FI (1) | FIC20250014I1 (hu) |
| FR (2) | FR24C1008I1 (hu) |
| HU (1) | HUS2500017I1 (hu) |
| IL (1) | IL213356A (hu) |
| MX (1) | MX2011006501A (hu) |
| NL (1) | NL301310I2 (hu) |
| NO (1) | NO2025013I1 (hu) |
| PL (1) | PL2379600T5 (hu) |
| PT (1) | PT2379600E (hu) |
| RU (1) | RU2562114C2 (hu) |
| TW (1) | TWI476003B (hu) |
| WO (1) | WO2010072691A1 (hu) |
| ZA (1) | ZA201104599B (hu) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110039218A (ko) | 2008-06-30 | 2011-04-15 | 노보 노르디스크 에이/에스 | 항-인간 인터루킨-20 항체 |
| UA112050C2 (uk) * | 2008-08-04 | 2016-07-25 | БАЄР ХЕЛСКЕР ЛЛСі | Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi) |
| PT2379600E (pt) * | 2008-12-22 | 2014-04-29 | Novo Nordisk As | Anticorpos contra inibidor da via de fator tecidual |
| US8454956B2 (en) | 2009-08-31 | 2013-06-04 | National Cheng Kung University | Methods for treating rheumatoid arthritis and osteoporosis with anti-IL-20 antibodies |
| SI3409289T1 (sl) * | 2010-02-26 | 2020-12-31 | Novo Nordisk A/S | Stabilni sestavki, ki vsebujejo protitelo |
| PL2542257T3 (pl) | 2010-03-01 | 2018-01-31 | Bayer Healthcare Llc | Zoptymalizowane przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI) |
| AU2011257219B2 (en) * | 2010-05-28 | 2014-12-04 | Novo Nordisk A/S | Stable multi-dose compositions comprising an antibody and a preservative |
| JP2013533871A (ja) * | 2010-06-30 | 2013-08-29 | ノヴォ ノルディスク アー/エス | 組織因子経路インヒビターに特異的に結合することが可能な抗体 |
| US9228022B2 (en) | 2010-06-30 | 2016-01-05 | Novo Nordisk A/S | Antibodies that are capable of specifically binding tissue factor pathway inhibitor |
| WO2012135671A2 (en) * | 2011-04-01 | 2012-10-04 | Bayer Healthcare Llc | Monoclonal antibodies against tissue factor pathway inhibitor (tfpi) |
| WO2014015133A1 (en) | 2012-07-19 | 2014-01-23 | National Cheng Kung University | Treatment of osteoarthritis using il-20 antagonists |
| US8603470B1 (en) | 2012-08-07 | 2013-12-10 | National Cheng Kung University | Use of IL-20 antagonists for treating liver diseases |
| US8852588B2 (en) | 2012-08-07 | 2014-10-07 | National Cheng Kung University | Treating allergic airway disorders using anti-IL-20 receptor antibodies |
| US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
| CN105209496A (zh) * | 2013-03-15 | 2015-12-30 | 拜尔健康护理有限责任公司 | 针对组织因子途径抑制剂的前体药物抗体 |
| EP2970497B1 (en) | 2013-03-15 | 2017-10-25 | Bayer HealthCare LLC | Anti-tfpi antibody variants with differential binding across ph range for improved pharmacokinetics |
| WO2014140240A1 (en) | 2013-03-15 | 2014-09-18 | Novo Nordisk A/S | Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor |
| JP6584397B2 (ja) * | 2013-07-19 | 2019-10-02 | ノヴォ ノルディスク アー/エス | 凝血促進活性を誘発することができる組織因子経路インヒビターのn末端部分を認識する抗体 |
| CA2921652A1 (en) | 2013-08-21 | 2015-02-26 | Manuel A. Riquelme | Compositions and methods for targeting connexin hemichannels |
| SG10201804945WA (en) * | 2013-12-12 | 2018-07-30 | Shanghai hengrui pharmaceutical co ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| CN106573977B (zh) * | 2014-04-27 | 2020-08-07 | 菲姆威有限公司 | 针对ceacam1的人源化抗体 |
| EP3194447B1 (en) * | 2014-09-17 | 2021-12-01 | Novo Nordisk A/S | Antibodies capable of binding two epitopes on tissue factor pathway inhibitor (1-161) |
| MX388251B (es) * | 2015-02-25 | 2025-03-19 | Mogam Inst Biomedical Res | Nuevo anticuerpo que se una a tfpi y composicion que comprende el mismo. |
| KR102438650B1 (ko) * | 2015-08-19 | 2022-08-31 | 화이자 인코포레이티드 | 조직 인자 경로 억제제 항체 및 그의 용도 |
| US10889637B2 (en) | 2016-02-26 | 2021-01-12 | The Board Of Regents Of The University Of Texas System | Methods of treating an osteolytic tumor and spinal cord injury by administering connexin (Cx) 43 hemichannel-binding antibodies |
| TWI788321B (zh) | 2017-01-20 | 2023-01-01 | 美商健臻公司 | 骨靶向抗體 |
| TWI856437B (zh) | 2017-01-20 | 2024-09-21 | 法商賽諾菲公司 | 抗TGF-β抗體及其用途 |
| JP7094722B2 (ja) * | 2018-02-28 | 2022-07-04 | キヤノン株式会社 | 画像読取装置及び画像形成装置 |
| KR102337683B1 (ko) | 2018-09-21 | 2021-12-13 | 주식회사 녹십자 | 고효율 항-tfpi 항체 조성물 |
| US20210395391A1 (en) * | 2018-10-11 | 2021-12-23 | Pfizer Inc. | Dosage Regimen for TFPI Antagonists |
| JP7774293B2 (ja) * | 2019-07-24 | 2025-11-21 | 国立研究開発法人科学技術振興機構 | 抗体酵素の革新的製造技術 |
| CN112442127A (zh) * | 2019-08-29 | 2021-03-05 | 苏州康宁杰瑞生物科技有限公司 | 针对tfpi的单克隆抗体 |
| MX2022005836A (es) * | 2019-11-13 | 2022-06-09 | Pfizer | Formulacion estable de anticuerpos acuosos. |
| MX2022015959A (es) * | 2020-07-02 | 2023-01-24 | Beijing Tuo Jie Biopharmaceutical Co Ltd | Anticuerpo anti-fxi/fxia, fragmento de union a antigeno del mismo y uso farmaceutico del mismo. |
| JP7278503B2 (ja) * | 2020-09-24 | 2023-05-19 | ノヴォ・ノルディスク・ヘルス・ケア・アーゲー | コンシズマブの医薬製剤およびその生産方法 |
| CN116136537A (zh) * | 2021-11-16 | 2023-05-19 | 北京积水潭医院 | 组织因子途径抑制物抗凝活性的检测方法和试剂盒及其应用 |
| CN118613492A (zh) * | 2022-01-30 | 2024-09-06 | 西湖大学 | Tfpi结合多肽及其用途 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4966852A (en) † | 1987-07-23 | 1990-10-30 | Monsanto Company | DNA clone of human tissue factor inhibitor |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| DK261490D0 (da) | 1990-10-31 | 1990-10-31 | Novo Nordisk As | New pharmaceutical compound |
| EP0539975A1 (en) † | 1991-10-31 | 1993-05-05 | Teijin Limited | Method for immunological assay of free lipoprotein-associated coagulation inhibitor (LACI) and kit therefor |
| JPH06153985A (ja) * | 1992-11-16 | 1994-06-03 | Teijin Ltd | モノクローナル抗体 |
| JPH06153981A (ja) | 1992-11-30 | 1994-06-03 | Teijin Ltd | Laciの免疫学的測定方法、それに用いるキット並びにモノクローナル抗体 |
| US5455338A (en) * | 1993-11-05 | 1995-10-03 | Zymogenetics, Inc. | DNA encoding novel human kunitz-type inhibitors and methods relating thereto |
| US5589359A (en) | 1994-08-05 | 1996-12-31 | Chiron Corporation | Chimeric proteins |
| JPH0875736A (ja) | 1994-09-06 | 1996-03-22 | Chemo Sero Therapeut Res Inst | ヒト組織因子凝固系インヒビターの定量法 |
| US5902582A (en) * | 1995-09-05 | 1999-05-11 | Chiron Corporation | Use of TFPI inhibitor for treatment of cancer |
| JP3681206B2 (ja) | 1995-12-26 | 2005-08-10 | 株式会社三菱化学ヤトロン | 抗ファクターXa・ティシュファクターパスウェイインヒビター複合体モノクローナル抗体及びその使用 |
| JP2002505574A (ja) | 1997-04-30 | 2002-02-19 | エンゾン,インコーポレイテッド | ポリアルキレンオキシド修飾された単鎖ポリペプチド |
| AU785038B2 (en) * | 2000-01-27 | 2006-08-31 | Applied Molecular Evolution, Inc. | Ultra high affinity neutralizing antibodies |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| JP2007534631A (ja) | 2003-10-28 | 2007-11-29 | ノボ ノルディスク アクティーゼルスカブ | ラミニン−5γ2結合性ペプチド、その関連組成物およびその使用 |
| US7585842B2 (en) | 2004-04-16 | 2009-09-08 | The Reagents Of The University Of California | Human kunitz-type inhibitor with enhanced antifibrinolytic activity |
| US7015746B1 (en) * | 2004-05-06 | 2006-03-21 | National Semiconductor Corporation | Bootstrapped bias mixer with soft start POR |
| DE602006021290D1 (de) † | 2005-03-04 | 2011-05-26 | Univ Illinois | Modulator von coagulationskaskaden und fibrinolytischen kaskaden |
| UA112050C2 (uk) * | 2008-08-04 | 2016-07-25 | БАЄР ХЕЛСКЕР ЛЛСі | Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi) |
| EP2379096B1 (en) * | 2008-12-19 | 2019-10-30 | Baxalta GmbH | Tfpi inhibitors and methods of use |
| CN102300876A (zh) * | 2008-12-22 | 2011-12-28 | 诺沃—诺迪斯克有限公司 | 针对组织因子途径抑制剂(tfpi)的抗体 |
| PT2379600E (pt) * | 2008-12-22 | 2014-04-29 | Novo Nordisk As | Anticorpos contra inibidor da via de fator tecidual |
| US8965454B2 (en) | 2009-03-04 | 2015-02-24 | Andrew Llc | Amplifier system for cell sites and other suitable applications |
| US8598327B2 (en) | 2009-08-18 | 2013-12-03 | Baxter International Inc. | Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics |
| MX2012002133A (es) | 2009-08-18 | 2013-02-15 | Baxter Healthcare Sa | Aptameros para inhibidor de trayectoria de factor de tejido y su uso como terapeuticos para trastorno de sangrado. |
| PL2542257T3 (pl) † | 2010-03-01 | 2018-01-31 | Bayer Healthcare Llc | Zoptymalizowane przeciwciała monoklonalne przeciwko inhibitorowi szlaku czynnika tkankowego (TFPI) |
| US8598008B2 (en) † | 2010-10-20 | 2013-12-03 | Texas Instruments Incorporated | Stacked ESD clamp with reduced variation in clamp voltage |
| AU2012214148A1 (en) † | 2011-02-11 | 2013-08-29 | Baxter Healthcare S.A. | Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics |
| WO2012135671A2 (en) † | 2011-04-01 | 2012-10-04 | Bayer Healthcare Llc | Monoclonal antibodies against tissue factor pathway inhibitor (tfpi) |
| EP2827910A2 (en) † | 2012-03-22 | 2015-01-28 | Baxter International Inc | Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics |
| WO2014140240A1 (en) | 2013-03-15 | 2014-09-18 | Novo Nordisk A/S | Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor |
| MX388251B (es) † | 2015-02-25 | 2025-03-19 | Mogam Inst Biomedical Res | Nuevo anticuerpo que se una a tfpi y composicion que comprende el mismo. |
| KR102438650B1 (ko) † | 2015-08-19 | 2022-08-31 | 화이자 인코포레이티드 | 조직 인자 경로 억제제 항체 및 그의 용도 |
-
2009
- 2009-12-18 PT PT97935431T patent/PT2379600E/pt unknown
- 2009-12-18 ES ES09793543T patent/ES2458665T5/es active Active
- 2009-12-18 MX MX2011006501A patent/MX2011006501A/es active IP Right Grant
- 2009-12-18 EP EP14151704.5A patent/EP2746294A3/en not_active Withdrawn
- 2009-12-18 RU RU2011129068/10A patent/RU2562114C2/ru active
- 2009-12-18 WO PCT/EP2009/067598 patent/WO2010072691A1/en not_active Ceased
- 2009-12-18 AU AU2009331570A patent/AU2009331570C1/en active Active
- 2009-12-18 BR BRPI0924058-6A patent/BRPI0924058B1/pt active IP Right Grant
- 2009-12-18 EP EP09793543.1A patent/EP2379600B2/en active Active
- 2009-12-18 PL PL09793543T patent/PL2379600T5/pl unknown
- 2009-12-18 CA CA2745317A patent/CA2745317C/en active Active
- 2009-12-18 US US13/140,296 patent/US8361469B2/en active Active
- 2009-12-18 KR KR1020167005204A patent/KR101745394B1/ko active Active
- 2009-12-18 DK DK09793543.1T patent/DK2379600T4/da active
- 2009-12-18 EP EP17176891.4A patent/EP3260466A1/en not_active Withdrawn
- 2009-12-18 KR KR1020117016958A patent/KR101600308B1/ko active Active
- 2009-12-18 CN CN200980157157.2A patent/CN102325795B/zh active Active
- 2009-12-18 JP JP2011541494A patent/JP5714505B2/ja active Active
- 2009-12-22 TW TW098144133A patent/TWI476003B/zh active
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2011
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2012
- 2012-12-20 US US13/721,802 patent/US8652471B2/en active Active
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2015
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2017
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2019
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2024
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2025
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- 2025-04-10 FR FR25C1014C patent/FR25C1014I1/fr active Active
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