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HUP9904180A3 - Thio acid derived monocyclic n-heteroaromatics and pharmaceutical compositions containing them - Google Patents

Thio acid derived monocyclic n-heteroaromatics and pharmaceutical compositions containing them

Info

Publication number
HUP9904180A3
HUP9904180A3 HU9904180A HUP9904180A HUP9904180A3 HU P9904180 A3 HUP9904180 A3 HU P9904180A3 HU 9904180 A HU9904180 A HU 9904180A HU P9904180 A HUP9904180 A HU P9904180A HU P9904180 A3 HUP9904180 A3 HU P9904180A3
Authority
HU
Hungary
Prior art keywords
heteroaromatics
pharmaceutical compositions
compositions containing
acid derived
thio acid
Prior art date
Application number
HU9904180A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of HUP9904180A2 publication Critical patent/HUP9904180A2/hu
Publication of HUP9904180A3 publication Critical patent/HUP9904180A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU9904180A 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heteroaromatics and pharmaceutical compositions containing them HUP9904180A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/731,128 US6004985A (en) 1996-10-09 1996-10-09 Thio acid derived monocylic N-heterocyclics as anticoagulants
PCT/EP1997/005231 WO1998015547A1 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heterocyclics as anticoagulants

Publications (2)

Publication Number Publication Date
HUP9904180A2 HUP9904180A2 (hu) 2000-09-28
HUP9904180A3 true HUP9904180A3 (en) 2000-11-28

Family

ID=24938188

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9904180A HUP9904180A3 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heteroaromatics and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (6) US6004985A (hu)
EP (1) EP0934310B1 (hu)
JP (1) JP3768244B2 (hu)
KR (1) KR20000048966A (hu)
CN (1) CN1111159C (hu)
AT (1) ATE288908T1 (hu)
AU (1) AU730060B2 (hu)
CA (1) CA2268172A1 (hu)
CZ (1) CZ122799A3 (hu)
DE (1) DE69732490T2 (hu)
DK (1) DK0934310T3 (hu)
ES (1) ES2236828T3 (hu)
HK (1) HK1020958A1 (hu)
HU (1) HUP9904180A3 (hu)
IL (1) IL129056A0 (hu)
NO (1) NO991594L (hu)
NZ (1) NZ334758A (hu)
PL (1) PL332602A1 (hu)
PT (1) PT934310E (hu)
SK (1) SK46499A3 (hu)
WO (1) WO1998015547A1 (hu)

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US6998515B1 (en) 1997-01-27 2006-02-14 Cornell Research Foundation, Inc. Use of a nucleic acid encoding a hypersensitive response elicitor polypeptide to enhance growth in plants
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US6262018B1 (en) 1997-08-06 2001-07-17 Cornell Research Foundation, Inc. Hypersensitive response elicitor from Erwinia amylovora and its use
US6228644B1 (en) 1997-08-06 2001-05-08 Cornell Research Foundation, Inc. Hypersensitive response elicitor from Erwinia amylovora, its use, and encoding gene
US6686364B2 (en) 1997-12-08 2004-02-03 Berlex Laboratories, Inc. Benzamidine derivatives and their use as anti-coagulants
US6140351A (en) * 1997-12-19 2000-10-31 Berlex Laboratories, Inc. Ortho-anthranilamide derivatives as anti-coagulants
SK9432000A3 (en) 1997-12-19 2001-02-12 Schering Ag Ortho-anthranilamide derivatives as anti-coagulants, pharmaceutical composition containing such derivatives and use thereof
US6713651B1 (en) * 1999-06-07 2004-03-30 Theravance, Inc. β2-adrenergic receptor agonists
US6960705B2 (en) 1998-10-05 2005-11-01 Eden Bioscience Corporation Nucleic acid encoding a hypersensitive response elicitor from Xanthomonas campestris
US6858707B1 (en) 1998-10-05 2005-02-22 Eden Bioscience Corporation Hypersensitive response elicitor fragments which are active but do not elicit a hypersensitive response
US6624139B1 (en) 1998-11-05 2003-09-23 Eden Bioscience Corporation Hypersensitive response elicitor-induced stress resistance
US6262088B1 (en) 1998-11-19 2001-07-17 Berlex Laboratories, Inc. Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants
US6127376A (en) 1998-12-04 2000-10-03 Berlex Laboratories, Inc. Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
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US6350761B1 (en) 1999-07-30 2002-02-26 Berlex Laboratories, Inc. Benzenamine derivatives as anti-coagulants
WO2003037346A1 (en) * 2001-10-31 2003-05-08 Cell Therapeutics, Inc. 6-phenyl-n-phenyl-(1,3,5) -triazine-2,4-diamine derivatives and related compounds with lysophphosphatidic acid acyltransferase beta (lpaat-beta) inhibitory activity for use in the treatment of cancer
TWI329105B (en) * 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
GB0206215D0 (en) 2002-03-15 2002-05-01 Novartis Ag Organic compounds
TW200409629A (en) 2002-06-27 2004-06-16 Bristol Myers Squibb Co 2,4-disubstituted-pyridine N-oxides useful as HIV reverse transcriptase inhibitors
US7517886B2 (en) 2002-07-29 2009-04-14 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
US7419984B2 (en) * 2002-10-17 2008-09-02 Cell Therapeutics, Inc. Pyrimidines and uses thereof
KR20040042071A (ko) * 2002-11-12 2004-05-20 박영민 인터넷 홈페이지를 활용한 경조사 자동알림 및 게시판 자동등록 방법
CA2507707C (en) 2002-12-03 2011-06-21 Axys Pharmaceuticals, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
US6875781B2 (en) * 2003-04-04 2005-04-05 Cell Therapeutics, Inc. Pyridines and uses thereof
EP1656372B1 (en) 2003-07-30 2013-04-10 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
EP1814878B1 (en) 2004-11-24 2012-01-04 Rigel Pharmaceuticals, Inc. Spiro-2, 4-pyrimidinediamine compounds and their uses
BRPI0606318B8 (pt) 2005-01-19 2021-05-25 Rigel Pharmaceuticals Inc composto, composição, e, uso de um composto
CA2604551A1 (en) * 2005-05-03 2007-03-08 Rigel Pharmaceuticals, Inc. Jak kinase inhibitors and their uses
US20070015834A1 (en) * 2005-07-18 2007-01-18 Moshe Flashner-Barak Formulations of fenofibrate containing PEG/Poloxamer
EA019973B1 (ru) * 2008-04-16 2014-07-30 Портола Фармасьютиклз, Инк. ИНГИБИТОРЫ Syk ПРОТЕИНКИНАЗ
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
EP3210609A1 (en) 2008-05-21 2017-08-30 Ariad Pharmaceuticals, Inc. Phosphorous derivatives as kinase inhibitors
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
US9834518B2 (en) 2011-05-04 2017-12-05 Ariad Pharmaceuticals, Inc. Compounds for inhibiting cell proliferation in EGFR-driven cancers
AU2012340555B2 (en) 2011-11-23 2016-10-20 Portola Pharmaceuticals, Inc. Pyrazine kinase inhibitors
WO2013169401A1 (en) 2012-05-05 2013-11-14 Ariad Pharmaceuticals, Inc. Compounds for inhibiting cell proliferation in egfr-driven cancers
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
US10487057B1 (en) * 2018-07-05 2019-11-26 Landos Biopharma, Inc. NLRX1 ligands
US10676436B2 (en) 2018-07-05 2020-06-09 Landos Biopharma, Inc. NLRX1 ligands
CN113527193B (zh) * 2020-04-18 2022-06-10 中国科学院精密测量科学与技术创新研究院 一种用于核磁氟谱检测的探针及其在检测巯基类化合物中的应用

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JPS5922697B2 (ja) * 1976-01-13 1984-05-28 エーザイ株式会社 ビス−（メタ−アミジノフエノキシ）−化合物
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WO1996028427A1 (en) * 1995-03-10 1996-09-19 Berlex Laboratories, Inc. Benzamidine derivatives their preparation and their use as anti-coagulants
US5691364A (en) * 1995-03-10 1997-11-25 Berlex Laboratories, Inc. Benzamidine derivatives and their use as anti-coagulants
US5663381A (en) * 1995-04-21 1997-09-02 Hexal Pharmaceuticals, Inc. Process for preparing form 1 ranitidine hydrochloride
US5612363A (en) * 1995-06-02 1997-03-18 Berlex Laboratories, Inc. N,N-di(aryl) cyclic urea derivatives as anti-coagulants
US5849759A (en) * 1995-12-08 1998-12-15 Berlex Laboratories, Inc. Naphthyl-substituted benzimidazole derivatives as anti-coagulants
US5994375A (en) * 1996-02-12 1999-11-30 Berlex Laboratories, Inc. Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants
US5693641A (en) * 1996-08-16 1997-12-02 Berlex Laboratories Inc. Bicyclic pyrimidine derivatives and their use as anti-coagulants
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US6008234A (en) * 1996-09-12 1999-12-28 Berlex Laboratories, Inc. Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants
CA2264521A1 (en) * 1996-09-12 1998-03-19 Schering Aktiengesellschaft Benzamidine derivatives substituted by cyclic amino acid or cyclic hydroxy acid derivatives and their use as anti-coagulants
US6004985A (en) * 1996-10-09 1999-12-21 Berlex Laboratories, Inc. Thio acid derived monocylic N-heterocyclics as anticoagulants
SK9432000A3 (en) * 1997-12-19 2001-02-12 Schering Ag Ortho-anthranilamide derivatives as anti-coagulants, pharmaceutical composition containing such derivatives and use thereof

Also Published As

Publication number Publication date
US6221886B1 (en) 2001-04-24
CA2268172A1 (en) 1998-04-16
AU730060B2 (en) 2001-02-22
PT934310E (pt) 2005-06-30
NO991594D0 (no) 1999-03-31
JP2001501632A (ja) 2001-02-06
DE69732490T2 (de) 2006-04-27
HK1020958A1 (en) 2004-03-19
ATE288908T1 (de) 2005-02-15
IL129056A0 (en) 2000-02-17
DK0934310T3 (da) 2005-05-30
US6004985A (en) 1999-12-21
DE69732490D1 (en) 2005-03-17
CN1233247A (zh) 1999-10-27
AU4624097A (en) 1998-05-05
NO991594L (no) 1999-06-08
JP3768244B2 (ja) 2006-04-19
PL332602A1 (en) 1999-09-27
WO1998015547A1 (en) 1998-04-16
KR20000048966A (ko) 2000-07-25
SK46499A3 (en) 2000-04-10
ES2236828T3 (es) 2005-07-16
NZ334758A (en) 2000-11-24
EP0934310A1 (en) 1999-08-11
CZ122799A3 (cs) 1999-09-15
US6166014A (en) 2000-12-26
EP0934310B1 (en) 2005-02-09
HUP9904180A2 (hu) 2000-09-28
US6162807A (en) 2000-12-19
US6034084A (en) 2000-03-07
CN1111159C (zh) 2003-06-11
US6150382A (en) 2000-11-21

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