HUP9903829A1 - RNS-vírusok fertőző klónjai,belőlük kifejlesztett vakcinák és diagnosztikai eljárások - Google Patents
RNS-vírusok fertőző klónjai,belőlük kifejlesztett vakcinák és diagnosztikai eljárásokInfo
- Publication number
- HUP9903829A1 HUP9903829A1 HU9903829A HUP9903829A HUP9903829A1 HU P9903829 A1 HUP9903829 A1 HU P9903829A1 HU 9903829 A HU9903829 A HU 9903829A HU P9903829 A HUP9903829 A HU P9903829A HU P9903829 A1 HUP9903829 A1 HU P9903829A1
- Authority
- HU
- Hungary
- Prior art keywords
- rna viruses
- vaccines
- infectious clones
- diagnostic assays
- assays derived
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 230000002458 infectious effect Effects 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- 238000003556 assay Methods 0.000 title 1
- 241001493065 dsRNA viruses Species 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
A találmány tárgya eljárás fertőző klónők előállítására RNS-vírűsőkgenőmjaiból kiindűlva. A találmány tárgyát képezik a találmányszerinti eljárásban alkalmazható rekőmbináns mőlekűlák, a rekőmbinánsmőlekűlákat tartalmazó módősítőtt RNS-vírűsők, a módősítőtt RNS-vírűsőkkal fertőzött sejtek és a módősítőtt RNS-vírűsőkat tartalmazóvakcinák is. A találmány szerinti megőldás alkalmas vakcinák ésdiagnősztikai eljárás kifejlesztésére kiválasztőtt RNS-vírűsőkgenőmjának felhasználása és módősítása útján. ŕ
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96203024A EP0839912A1 (en) | 1996-10-30 | 1996-10-30 | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| PCT/NL1997/000593 WO1998018933A1 (en) | 1996-10-30 | 1997-10-29 | Infectious clones of rna viruses and vaccines and diagnostic assays derived thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9903829A1 true HUP9903829A1 (hu) | 2000-03-28 |
| HUP9903829A3 HUP9903829A3 (en) | 2001-06-28 |
Family
ID=8224533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9903829A HUP9903829A3 (en) | 1996-10-30 | 1997-10-29 | Infectious clones of rna viruses and vaccines and diagnostic assays derived thereof |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US6268199B1 (hu) |
| EP (2) | EP0839912A1 (hu) |
| JP (1) | JP3921552B2 (hu) |
| KR (1) | KR100437254B1 (hu) |
| CN (1) | CN1138859C (hu) |
| AT (1) | ATE366314T1 (hu) |
| AU (1) | AU719991B2 (hu) |
| BR (1) | BR9712592A (hu) |
| CA (1) | CA2272046C (hu) |
| CZ (1) | CZ294781B6 (hu) |
| DE (1) | DE69737886T2 (hu) |
| DK (1) | DK0935660T3 (hu) |
| ES (1) | ES2290973T3 (hu) |
| HU (1) | HUP9903829A3 (hu) |
| ID (1) | ID22208A (hu) |
| MY (1) | MY117686A (hu) |
| PL (1) | PL191258B1 (hu) |
| PT (1) | PT935660E (hu) |
| SI (1) | SI0935660T1 (hu) |
| SK (1) | SK286231B6 (hu) |
| UA (1) | UA72433C2 (hu) |
| WO (1) | WO1998018933A1 (hu) |
| ZA (1) | ZA979732B (hu) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0839912A1 (en) * | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| EP0974660A1 (en) * | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Newcastle disease virus infectious clones, vaccines and diagnostic assays |
| US7618797B2 (en) * | 1998-12-22 | 2009-11-17 | Pfizer Inc | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| CA2440933A1 (en) * | 1998-12-22 | 2000-06-22 | Pfizer Products Inc. | An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof |
| US7691389B2 (en) | 1998-12-22 | 2010-04-06 | Pfizer Inc | Infectious cDNA clone of north american porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| US7132106B2 (en) * | 1998-12-22 | 2006-11-07 | Pfizer Inc. | Infectious cDNA clone of North American porcine reproductive and respiratory syndrome (PRRS) virus and uses thereof |
| EP1157121B1 (en) | 1999-03-08 | 2013-04-24 | Boehringer Ingelheim Vetmedica GmbH | Prrsv replicon |
| JP4778620B2 (ja) | 1999-04-22 | 2011-09-21 | ユナイテッド ステイツ デパートメント オブ アグリカルチャー | 分離株ja−142に基づく、豚繁殖・呼吸障害症候群ワクチン |
| JP2003520601A (ja) * | 2000-01-26 | 2003-07-08 | ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング | Prrsvの組み換え弱毒化 |
| EP1156111A1 (en) * | 2000-05-19 | 2001-11-21 | Stichting Dienst Landbouwkundig Onderzoek | Chimeric arterivirus-like particles |
| ES2340499T3 (es) | 2001-06-05 | 2010-06-04 | Curevac Gmbh | Arnm de antigeno tumoral estabilizado con un contenido de g/c aumentado. |
| DE10162480A1 (de) | 2001-12-19 | 2003-08-07 | Ingmar Hoerr | Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen |
| US6841364B2 (en) * | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
| DE10229872A1 (de) * | 2002-07-03 | 2004-01-29 | Curevac Gmbh | Immunstimulation durch chemisch modifizierte RNA |
| DE10347710B4 (de) | 2003-10-14 | 2006-03-30 | Johannes-Gutenberg-Universität Mainz | Rekombinante Impfstoffe und deren Verwendung |
| EP1781327A4 (en) | 2004-06-18 | 2009-02-25 | Univ Minnesota | IDENTIFICATION OF VIRAL INFECTED AND VACCINATED ORGANISMS |
| KR100872840B1 (ko) | 2004-07-09 | 2008-12-22 | (주)씨아이디 | 돼지생식기호흡기증후군 바이러스에 대한 전체-길이의감염성이 있는 cDNA 클론 및 이의 용도 |
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| PL2369001T3 (pl) | 2005-06-24 | 2017-06-30 | Regents Of The University Of Minnesota | Wirusy PRRS, ich klony zakaźne, mutanty i sposoby stosowania |
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| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
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