HUP9901717A3 - A process for the optical purification of enantiomerically enriched benzimidazole derivatives - Google Patents

A process for the optical purification of enantiomerically enriched benzimidazole derivatives

Info

Publication number: HUP9901717A3
Authority: HU; Hungary
Prior art keywords: enantiomerically enriched; benzimidazole derivatives; optical purification; enriched benzimidazole; purification
Prior art date: 1995-07-03

Application number

HU9901717A

Other languages

English (en)

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-03

Filing date

1996-06-26

Publication date

2002-03-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20397468&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9901717(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-06-26 Application filed by Astra Ab filed Critical Astra Ab

2000-04-28 Publication of HUP9901717A2 publication Critical patent/HUP9901717A2/hu

2002-03-28 Publication of HUP9901717A3 publication Critical patent/HUP9901717A3/hu

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HU9901717A 1995-07-03 1996-06-26 A process for the optical purification of enantiomerically enriched benzimidazole derivatives HUP9901717A3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9500817		1995-07-03

Publications (2)

Publication Number	Publication Date
HUP9901717A2 HUP9901717A2 (hu)	2000-04-28
HUP9901717A3 true HUP9901717A3 (en)	2002-03-28

Family

ID=20397468

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9901717A HUP9901717A3 (en)	1995-07-03	1996-06-26	A process for the optical purification of enantiomerically enriched benzimidazole derivatives

Country Status (36)

Country	Link
US (1)	US5929244A (hu)
EP (2)	EP1498416A1 (hu)
JP (1)	JP4195507B2 (hu)
KR (1)	KR100451078B1 (hu)
CN (1)	CN1098261C (hu)
AT (1)	ATE418549T1 (hu)
AU (1)	AU698638B2 (hu)
BR (1)	BR9609450A (hu)
CA (1)	CA2226184C (hu)
CZ (1)	CZ295430B6 (hu)
DE (1)	DE69637788D1 (hu)
DK (1)	DK0836601T3 (hu)
DZ (1)	DZ2057A1 (hu)
EE (1)	EE03444B1 (hu)
ES (1)	ES2318850T3 (hu)
HR (1)	HRP960232A2 (hu)
HU (1)	HUP9901717A3 (hu)
IL (1)	IL122811A (hu)
IS (1)	IS2666B (hu)
MA (1)	MA23921A1 (hu)
MY (1)	MY114018A (hu)
NO (1)	NO313008B1 (hu)
NZ (1)	NZ311842A (hu)
PL (1)	PL186702B1 (hu)
PT (1)	PT836601E (hu)
RS (1)	RS49826B (hu)
RU (1)	RU2144031C1 (hu)
SA (1)	SA96170103B1 (hu)
SI (1)	SI0836601T1 (hu)
SK (1)	SK284780B6 (hu)
TN (1)	TNSN96090A1 (hu)
TR (1)	TR199701754T1 (hu)
TW (1)	TW444010B (hu)
UA (1)	UA49838C2 (hu)
WO (1)	WO1997002261A1 (hu)
ZA (1)	ZA965205B (hu)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP960232A2 (en) *	1995-07-03	1998-02-28	Astra Ab	A process for the optical purification of compounds
US6489346B1 (en)	1996-01-04	2002-12-03	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) *	1996-01-04	2003-11-11	Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US5840737A (en)	1996-01-04	1998-11-24	The Curators Of The University Of Missouri	Omeprazole solution and method for using same
US6699885B2 (en)	1996-01-04	2004-03-02	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and methods of using same
AU6551198A (en) *	1997-05-30	1998-12-30	Dr. Reddy's Research Foundation	Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
AU742620B2 (en) *	1998-01-30	2002-01-10	Sepracor, Inc.	R-lansoprazole compositions and methods
SE9900274D0 (sv)	1999-01-28	1999-01-28	Astra Ab	New compound
TWI275587B (en)	1999-06-17	2007-03-11	Takeda Chemical Industries Ltd	A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
CA2375091A1 (en)	1999-06-30	2001-01-11	Takeda Chemical Industries, Ltd.	Crystals of benzimidazole compounds
US6316020B1 (en)	1999-08-26	2001-11-13	Robert R. Whittle	Pharmaceutical formulations
US6326384B1 (en)	1999-08-26	2001-12-04	Robert R. Whittle	Dry blend pharmaceutical unit dosage form
US6312712B1 (en)	1999-08-26	2001-11-06	Robert R. Whittle	Method of improving bioavailability
US6262085B1 (en)	1999-08-26	2001-07-17	Robert R. Whittle	Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262086B1 (en)	1999-08-26	2001-07-17	Robert R. Whittle	Pharmaceutical unit dosage form
US6312723B1 (en)	1999-08-26	2001-11-06	Robert R. Whittle	Pharmaceutical unit dosage form
US6268385B1 (en)	1999-08-26	2001-07-31	Robert R. Whittle	Dry blend pharmaceutical formulations
US6369087B1 (en)	1999-08-26	2002-04-09	Robert R. Whittle	Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6780880B1 (en)	1999-08-26	2004-08-24	Robert R. Whittle	FT-Raman spectroscopic measurement
EP1293507B1 (en)	2000-05-15	2007-11-28	Takeda Pharmaceutical Company Limited	Process for producing crystal
ATE342263T1 (de)	2000-08-04	2006-11-15	Takeda Pharmaceutical	Salze von benzimidazol-derivaten und deren verwendung
AU2002218506A1 (en)	2000-12-01	2002-06-11	Takeda Chemical Industries Ltd.	Process for the crystallization of (r)- or (s)-lansoprazole
KR100433735B1 (ko) *	2001-06-27	2004-06-04	주식회사 씨트리	결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0104295D0 (sv) *	2001-12-18	2001-12-18	Astrazeneca Ab	New process
JP2005521662A (ja) *	2002-01-25	2005-07-21	サンタラスインコーポレイティッド	プロトンポンプ阻害剤の経粘膜送達
AU2003273000A1 (en)	2002-10-16	2004-05-04	Takeda Pharmaceutical Company Limited	Stable solid preparations
MY148805A (en)	2002-10-16	2013-05-31	Takeda Pharmaceutical	Controlled release preparation
DE10254167A1 (de)	2002-11-20	2004-06-09	Icon Genetics Ag	Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen
ME00563A (en)	2002-12-06	2011-12-20		Process for preparing optically pure active compounds
BR0316702A (pt)	2002-12-06	2005-10-18	Altana Pharma Ag	xprocesso para preparação de (s)-pantoprazol
WO2004073654A2 (en) *	2003-02-20	2004-09-02	Santarus, Inc.	A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid
BRPI0407906A (pt) *	2003-02-28	2006-02-14	Ranbaxy Lab Ltd	polimorfos de s-omeprazol
US8993599B2 (en)	2003-07-18	2015-03-31	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2531566C (en) *	2003-07-18	2013-05-07	Santarus, Inc.	Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US7005732B2 (en) *	2003-10-21	2006-02-28	Honeywell International Inc.	Methods and systems for providing MEMS devices with a top cap and upper sense plate
FR2863609A1 (fr) *	2003-12-15	2005-06-17	Isochem Sa	Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides
SE0400410D0 (sv) *	2004-02-20	2004-02-20	Astrazeneca Ab	New compounds
US8906940B2 (en) *	2004-05-25	2014-12-09	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) *	2004-05-25	2014-08-26	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2006009602A2 (en)	2004-06-16	2006-01-26	Tap Pharmaceutical Products, Inc.	Multiple ppi dosage form
FR2876101B1 (fr) *	2004-10-05	2007-03-02	Sidem Pharma Sa Sa	Procede de preparation enantioselective de derives de sulfoxydes
EP1801110A1 (en)	2005-12-22	2007-06-27	KRKA, tovarna zdravil, d.d., Novo mesto	Esomeprazole arginine salt
US7553857B2 (en)	2005-12-23	2009-06-30	Lek Pharmaceuticals D.D.	S-omeprazole magnesium
US7786309B2 (en) *	2006-06-09	2010-08-31	Apotex Pharmachem Inc.	Process for the preparation of esomeprazole and salts thereof
FR2909380B1 (fr) *	2006-12-04	2009-02-20	Sidem Pharma Sa Sa	Conglomerats de sels de potassium de tenatoprazole
EP1947099A1 (en)	2007-01-18	2008-07-23	LEK Pharmaceuticals D.D.	Process for solvent removal from omeprazole salts
KR101432866B1 (ko) *	2007-06-15	2014-08-26	엠큐어 파마슈티컬즈 리미티드	생활성 화합물의 설폭사이드화 방법
CN101323609B (zh) *	2007-06-15	2013-05-01	成都福瑞生物工程有限公司	不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法
FR2920428B1 (fr) *	2007-08-29	2012-06-15	Univ Rouen	Procede de dedoublement de sels de l'omeprazole
ES2638463T3 (es)	2008-03-10	2017-10-20	Takeda Pharmaceutical Company Limited	Cristal de compuesto de bencimidazol
EP2346854A4 (en)	2008-11-18	2012-10-17	Hetero Research Foundation	OPTICAL PURIFICATION OF ESOMEPRAZOLE
KR101001646B1 (ko) *	2008-12-12	2010-12-17	한미약품 주식회사	(ｒ)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체
WO2011004387A2 (en)	2009-06-18	2011-01-13	Matrix Laboratories Ltd	Process for the preparation of dexlansoprazole polymorphic forms
WO2011058569A1 (en)	2009-11-12	2011-05-19	Hetero Research Foundation	Process for the resolution of omeprazole
US20130197232A1 (en)	2010-01-29	2013-08-01	Ranbaxy Laboratories Limited	Process for the preparation of crystalline forms of dexlansoprazole
JP6574773B2 (ja) *	2014-07-30	2019-09-11	株式会社アエタスファルマ	１，４−ベンゾチアゼピン−１−オキシド誘導体の光学異性体、及びそれを用いた医薬組成物
EP3064495B1 (en) *	2015-03-06	2016-12-14	F.I.S.- Fabbrica Italiana Sintetici S.p.A.	Improved process for the preparation of optically pure esomeprazole

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE7804231L (sv) *	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
JPS6150978A (ja) *	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
AU4640985A (en) *	1984-08-31	1986-03-06	Nippon Chemiphar Co. Ltd.	Benzimidazole derivatives
FI90544C (fi) *	1986-11-13	1994-02-25	Eisai Co Ltd	Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
DE69011645T2 (de) *	1989-11-29	1995-01-12	Toa Eiyo Ltd	Cycloheptenopyridinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Antiulkusmitteln.
DE4035455A1 (de) *	1990-11-08	1992-05-14	Byk Gulden Lomberg Chem Fab	Enantiomerentrennung
SE9301830D0 (sv) *	1993-05-28	1993-05-28	Ab Astra	New compounds
IS4232A (is) *	1993-12-06	1995-06-07	Astra Aktiebolag	Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
HRP960232A2 (en) *	1995-07-03	1998-02-28	Astra Ab	A process for the optical purification of compounds

1996
- 1996-05-21 HR HRPCT/SE95/00817A patent/HRP960232A2/hr not_active Application Discontinuation
- 1996-06-19 SA SA96170103A patent/SA96170103B1/ar unknown
- 1996-06-19 ZA ZA965205A patent/ZA965205B/xx unknown
- 1996-06-19 RS YUP-376/96A patent/RS49826B/sr unknown
- 1996-06-22 TW TW085107517A patent/TW444010B/zh not_active IP Right Cessation
- 1996-06-26 US US08/676,215 patent/US5929244A/en not_active Expired - Lifetime
- 1996-06-26 HU HU9901717A patent/HUP9901717A3/hu not_active Application Discontinuation
- 1996-06-26 ES ES96922339T patent/ES2318850T3/es not_active Expired - Lifetime
- 1996-06-26 NZ NZ311842A patent/NZ311842A/xx not_active IP Right Cessation
- 1996-06-26 SK SK1793-97A patent/SK284780B6/sk not_active IP Right Cessation
- 1996-06-26 DZ DZ960101A patent/DZ2057A1/fr active
- 1996-06-26 DE DE69637788T patent/DE69637788D1/de not_active Expired - Lifetime
- 1996-06-26 EP EP04024339A patent/EP1498416A1/en not_active Withdrawn
- 1996-06-26 CN CN96196465A patent/CN1098261C/zh not_active Expired - Lifetime
- 1996-06-26 AT AT96922339T patent/ATE418549T1/de active
- 1996-06-26 PT PT96922339T patent/PT836601E/pt unknown
- 1996-06-26 BR BR9609450A patent/BR9609450A/pt not_active Application Discontinuation
- 1996-06-26 CA CA002226184A patent/CA2226184C/en not_active Expired - Lifetime
- 1996-06-26 DK DK96922339T patent/DK0836601T3/da active
- 1996-06-26 IL IL12281196A patent/IL122811A/xx not_active IP Right Cessation
- 1996-06-26 EP EP96922339A patent/EP0836601B1/en not_active Expired - Lifetime
- 1996-06-26 KR KR1019970709953A patent/KR100451078B1/ko not_active Expired - Fee Related
- 1996-06-26 SI SI9630766T patent/SI0836601T1/sl unknown
- 1996-06-26 TR TR97/01754T patent/TR199701754T1/xx unknown
- 1996-06-26 RU RU98101727A patent/RU2144031C1/ru not_active IP Right Cessation
- 1996-06-26 PL PL96324394A patent/PL186702B1/pl not_active IP Right Cessation
- 1996-06-26 EE EE9700368A patent/EE03444B1/xx not_active IP Right Cessation
- 1996-06-26 WO PCT/SE1996/000841 patent/WO1997002261A1/en not_active Ceased
- 1996-06-26 AU AU63240/96A patent/AU698638B2/en not_active Expired
- 1996-06-26 JP JP50506397A patent/JP4195507B2/ja not_active Expired - Lifetime
- 1996-06-26 CZ CZ19974211A patent/CZ295430B6/cs not_active IP Right Cessation
- 1996-06-26 UA UA97126300A patent/UA49838C2/uk unknown
- 1996-06-28 MA MA24295A patent/MA23921A1/fr unknown
- 1996-07-02 TN TNPCT/SE1995/000817A patent/TNSN96090A1/fr unknown
- 1996-07-03 MY MYPI96002734A patent/MY114018A/en unknown
1997
- 1997-01-21 IS IS4638A patent/IS2666B/is unknown
- 1997-12-22 NO NO19976030A patent/NO313008B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0836601A1 (en)	1998-04-22
SA96170103B1 (ar)	2006-07-30
IS2666B (is)	2010-08-15
IL122811A (en)	2000-11-21
UA49838C2 (uk)	2002-10-15
WO1997002261A1 (en)	1997-01-23
CZ421197A3 (cs)	1998-06-17
ATE418549T1 (de)	2009-01-15
MA23921A1 (fr)	1996-12-31
HRP960232A2 (en)	1998-02-28
RS49826B (sr)	2008-08-07
TNSN96090A1 (fr)	2005-03-15
DE69637788D1 (de)	2009-02-05
EP0836601B1 (en)	2008-12-24
MX9800160A (es)	1998-03-31
PT836601E (pt)	2009-02-17
EE9700368A (et)	1998-06-15
ZA965205B (en)	1997-01-03
SI0836601T1 (sl)	2009-04-30
CN1193971A (zh)	1998-09-23
YU37696A (sh)	1999-03-04
DZ2057A1 (fr)	2002-10-20
EP1498416A1 (en)	2005-01-19
JP4195507B2 (ja)	2008-12-10
KR19990028631A (ko)	1999-04-15
AU698638B2 (en)	1998-11-05
PL186702B1 (pl)	2004-02-27
NO313008B1 (no)	2002-07-29
PL324394A1 (en)	1998-05-25
CA2226184C (en)	2008-08-05
NZ311842A (en)	1998-12-23
HUP9901717A2 (hu)	2000-04-28
ES2318850T3 (es)	2009-05-01
SK179397A3 (en)	1998-09-09
HK1010193A1 (en)	1999-06-17
CZ295430B6 (cs)	2005-08-17
NO976030L (no)	1998-02-09
IL122811A0 (en)	1998-08-16
KR100451078B1 (ko)	2004-11-16
JPH11508590A (ja)	1999-07-27
TW444010B (en)	2001-07-01
TR199701754T1 (xx)	1998-04-21
BR9609450A (pt)	1999-03-02
IS4638A (is)	1997-12-22
CA2226184A1 (en)	1997-01-23
NO976030D0 (no)	1997-12-22
CN1098261C (zh)	2003-01-08
RU2144031C1 (ru)	2000-01-10
MY114018A (en)	2002-07-31
EE03444B1 (et)	2001-06-15
SK284780B6 (sk)	2005-11-03
DK0836601T3 (da)	2009-03-16
US5929244A (en)	1999-07-27
AU6324096A (en)	1997-02-05

Publication	Publication Date	Title
HUP9901717A3 (en)	2002-03-28	A process for the optical purification of enantiomerically enriched benzimidazole derivatives
PL323475A1 (en)	1998-03-30	Large-scale paragene purification process
EP0764673A3 (en)	1997-10-08	Process for the production of polycarbonate
EP0693513A3 (en)	1997-01-02	Process for polyether cleaning
LTIP417A (en)	1994-10-25	A process for the purification of water
PL321596A1 (en)	1997-12-08	Melamine purification process
AU5546796A (en)	1996-10-30	A simple method for the purification of a bioelastic polymer
GR3032600T3 (en)	2000-05-31	Process for the production of imidazo-benzodiazepine derivatives
EP0857790A4 (en)	1999-08-18	METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUNDS
AU6821396A (en)	1997-03-12	Purification process
EE03393B1 (et)	2001-04-16	Protsess enantiomeerselt puhta asetidiin-2-karboksüülhappe saamiseks
AU681215B2 (en)	1997-08-21	A process for the purification of fullerenes
IL117849A0 (en)	1996-08-04	Process for the purification of glycoproteins
EP0474182A3 (en)	1992-08-12	Method for the purification of a bifidobacteria-proliferating substance
IL115564A0 (en)	1996-01-19	A process for the production of ascorbic acid
IL123617A0 (en)	1998-10-30	Process for the purification of diphenyl ether compounds
EP0864597A4 (en)	1999-07-21	METHOD FOR PRODUCING POLYCARBONATE
EP0783039A4 (en)	1999-11-17	METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ALKOXYCYCLOHEXANOL DERIVATIVES
EP0728722A3 (de)	1997-01-08	Verfahren zur Herstellung von Hydroxymethyl-cyclopropan
IL131765A0 (en)	2001-03-19	Process for the purification of substituted p-nitrodiphenylethers
GB2305874B (en)	1998-06-10	Production of purified water process systems
AU3218993A (en)	1994-08-18	A method for the purification of water
ZA962914B (en)	1996-10-17	Process for the purification of glycoproteins
HU9601362D0 (en)	1996-07-29	Process for producing optically active compounds
IL110901A0 (en)	1994-11-28	A process for the purification of sewage

Legal Events

Date	Code	Title	Description
2012-07-30	FC4A	Lapse of provisional application due to refusal