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HUP0103707A2 - Stabil oxaliplatinaoldat-formuláció - Google Patents

Stabil oxaliplatinaoldat-formuláció

Info

Publication number
HUP0103707A2
HUP0103707A2 HU0103707A HUP0103707A HUP0103707A2 HU P0103707 A2 HUP0103707 A2 HU P0103707A2 HU 0103707 A HU0103707 A HU 0103707A HU P0103707 A HUP0103707 A HU P0103707A HU P0103707 A2 HUP0103707 A2 HU P0103707A2
Authority
HU
Hungary
Prior art keywords
oxalyplatinum
formulation
stable
solution
stable oxalyplatinum
Prior art date
Application number
HU0103707A
Other languages
English (en)
Inventor
Nicholas Hugh Anderson
Ross Blundell
Stephen Brown
David Alan England
Martin Robert Gray
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10827600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0103707(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of HUP0103707A2 publication Critical patent/HUP0103707A2/hu
Publication of HUP0103707A3 publication Critical patent/HUP0103707A3/hu
Publication of HU224611B1 publication Critical patent/HU224611B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HU0103707A 1998-02-25 1999-02-25 Stabil oxaliplatinaoldat-formuláció HU224611B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9804013.2A GB9804013D0 (en) 1998-02-25 1998-02-25 Formulations
PCT/GB1999/000572 WO1999043355A2 (en) 1998-02-25 1999-02-25 Formulations containing oxaliplatin

Publications (3)

Publication Number Publication Date
HUP0103707A2 true HUP0103707A2 (hu) 2002-02-28
HUP0103707A3 HUP0103707A3 (en) 2004-07-28
HU224611B1 HU224611B1 (hu) 2005-11-28

Family

ID=10827600

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103707A HU224611B1 (hu) 1998-02-25 1999-02-25 Stabil oxaliplatinaoldat-formuláció

Country Status (27)

Country Link
US (1) US6306902B1 (hu)
EP (1) EP0943331B1 (hu)
JP (1) JP4430229B2 (hu)
KR (1) KR20010041182A (hu)
CN (1) CN1152718C (hu)
AR (1) AR015524A1 (hu)
AT (1) ATE202472T1 (hu)
AU (1) AU757101B2 (hu)
BR (1) BR9908273A (hu)
CA (1) CA2261500C (hu)
CZ (1) CZ302196B6 (hu)
DE (1) DE69900162T2 (hu)
DK (1) DK0943331T3 (hu)
ES (1) ES2161085T3 (hu)
GB (1) GB9804013D0 (hu)
GR (1) GR3036646T3 (hu)
GT (1) GT199900019A (hu)
HU (1) HU224611B1 (hu)
IL (1) IL137772A (hu)
MX (1) MXPA00008195A (hu)
NO (1) NO329900B1 (hu)
PL (1) PL197948B1 (hu)
PT (1) PT943331E (hu)
RU (1) RU2207857C2 (hu)
UA (1) UA70316C2 (hu)
WO (1) WO1999043355A2 (hu)
ZA (1) ZA991489B (hu)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9804013D0 (en) 1998-02-25 1998-04-22 Sanofi Sa Formulations
HK1039280B (zh) * 1998-10-14 2003-02-14 Debiopharm S.A. 奥沙利铂制剂包装
US7070796B1 (en) 1999-08-30 2006-07-04 Debiopharm S.A. Pharmaceutically stable oxaliplatinum preparation for parenteral administration
JP4890711B2 (ja) * 1999-08-30 2012-03-07 デビオファーム ソシエテ アノニム 非経口投与のための医薬として安定なオキザリプラチナム製剤
WO2002047725A2 (fr) * 2000-12-12 2002-06-20 Debiopharm S.A. Preparation pharmaceutique d'oxaliplatine pour administration par voie parenterale et procede d'obtention de ladite preparation
ES2287238T3 (es) 2001-03-02 2007-12-16 Debiopharm S.A. Utilizacion de un vial que contiene una solucion de oxaliplatino.
US20040186172A1 (en) 2001-07-02 2004-09-23 Houssam Ibrahim Oxaliplatin active substance with a very low content of oxalic acid
US6476068B1 (en) * 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
US20050020556A1 (en) * 2003-05-30 2005-01-27 Kosan Biosciences, Inc. Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
CA2537170A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
CZ300795B6 (cs) * 2003-09-02 2009-08-12 Pliva-Lachema A. S. Farmaceutická kompozice a zpusob její výroby
JP2007504177A (ja) * 2003-09-02 2007-03-01 プリヴァ−ラケマ，エー．エス． 医薬組成物、その製造方法及び治療上の使用
WO2005051966A1 (en) 2003-11-25 2005-06-09 Platco Technologies (Proprietary) Limited Platinum(ii) complexes, preparation and use
RU2335512C2 (ru) * 2003-12-10 2008-10-10 Тоудаи Тло, Лтд. Координационный комплекс диаминоциклогексана платины (ii) с блоксополимером, содержащим сегмент поли(карбоновой кислоты), и включающий его противораковый агент
CN100471493C (zh) * 2003-12-17 2009-03-25 梅比欧法姆股份有限公司 含有奥沙利铂的脂质体制剂
WO2005102312A1 (en) * 2004-04-27 2005-11-03 Mayne Pharma Limited Concentrated oxaliplatin solutions
CA2576834A1 (en) 2004-09-01 2006-03-09 Platco Technologies (Proprietary) Limited Preparation of platinum(ii) complexes
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
EP1879568B1 (en) * 2005-03-28 2009-05-06 Dabur Pharma Limited Stable pharmaceutical compositions of platinum (ii) antitumour agents
US7605282B2 (en) * 2005-04-09 2009-10-20 Vuab Pharma A.S. Process for the preparation of an oxaliplatin preparation
RU2292210C1 (ru) * 2005-05-03 2007-01-27 Институт химии и химической технологии СО РАН (ИХХТ СО РАН) Способ получения стерилизованной микрокристаллической цис-дихлородиамминплатины (ii)
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (en) * 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
KR20080096682A (ko) 2006-01-30 2008-10-31 플라트코 테크놀로지스 (프로프라이어터리) 리미티드 백금(ⅱ) 착물의 제조법
KR100913063B1 (ko) 2006-09-13 2009-08-21 주식회사유한양행 옥살리플라틴-함유 주사용 용액
BRPI0806728A2 (pt) * 2007-01-22 2011-09-13 Pliva Lachema As composição farmacêutica, e, método de produzir a mesma
RU2340347C2 (ru) * 2007-01-24 2008-12-10 Институт химии и химической технологии СО РАН (ИХХТ СО РАН) Способ получения стерилизованной микрокристаллической соли цис-дихлороамминизопропиламинплатины (ii)
US20100267824A1 (en) * 2007-11-12 2010-10-21 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
US20090130017A1 (en) * 2007-11-19 2009-05-21 Searete Llc Targeted short-lived drug delivery
US9023834B2 (en) * 2008-11-13 2015-05-05 Taigen Biotechnology Co., Ltd. Lyophilization formulation
CN101461801B (zh) * 2008-12-26 2013-05-15 辰欣药业股份有限公司 一种奥沙利铂药物组合物及其制备方法
EP2481396A4 (en) 2009-09-21 2014-03-05 Jw Pharmaceutical Corp OXALIPLATIN NANOPARTICLES AND MANUFACTURING METHOD THEREFOR
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
CN104523674B (zh) * 2014-12-11 2017-10-24 广州市上为医药科技有限公司 一种以奥沙利铂为主药成分的注射用组合物
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
CN104829653B (zh) * 2015-05-06 2016-03-23 山东罗欣药业集团股份有限公司 一种奥沙利铂水合物晶体及其冻干粉针剂
CA3251941A1 (en) 2018-01-12 2025-02-24 Metimedi Pharmaceuticals Co., Ltd. Methods of treating chronic inflammatory diseases

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JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
PT93772A (pt) 1989-04-17 1991-01-08 Searle & Co Processo para a preparacao de composicoes para o tratamento de neoplasias, contendo um agente anti-neoplastico, por exemplo doxorubicina e um agente protector para reduzir os efeitos secundarios, por exemplo carbetimer
WO1991009042A1 (fr) 1989-12-15 1991-06-27 Tsumura & Co. Nouveau complexe de platine et medicament antitumoral le contenant comme ingredient actif
JPH04185601A (ja) * 1990-11-20 1992-07-02 Unitika Ltd 白金抗癌剤徐放性製剤
ZA928771B (en) * 1991-11-15 1993-09-08 Smithkline Beecham Corp Combination chemotherapy
JPH0776230B2 (ja) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
JPH05238936A (ja) 1992-02-27 1993-09-17 Dainippon Pharmaceut Co Ltd カルシトリオールの水性液剤
JP2673331B2 (ja) * 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
JPH06287021A (ja) * 1992-04-22 1994-10-11 Tanaka Kikinzoku Kogyo Kk 光学活性な白金錯化合物の光学的分割方法
AU5416394A (en) * 1992-11-24 1994-06-22 Debiopharm S.A. Cisplatinum/oxaliplatinum combination
JP3025602B2 (ja) * 1993-05-21 2000-03-27 デビオファーム エス．アー． 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法
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ES2152412T3 (es) * 1994-08-08 2001-02-01 Debiopharm Sa Preparacion farmaceuticamente estable de oxaliplatino.
EP0715854B1 (en) * 1994-11-11 2003-09-10 Debiopharm S.A. Carcinostatic compositions containing cis-oxaliplatinum and one or more other compatible carcinostatic substances
FR2740686B1 (fr) * 1995-11-03 1998-01-16 Sanofi Sa Formulation pharmaceutique lyophilisee stable
EP0801070B1 (en) 1996-04-10 2003-04-16 Debiopharm S.A. Process of preparing platinum compound
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GB9804013D0 (en) 1998-02-25 1998-04-22 Sanofi Sa Formulations

Also Published As

Publication number Publication date
HK1036405A1 (en) 2002-01-04
WO1999043355A3 (en) 1999-11-04
NO329900B1 (no) 2011-01-24
US6306902B1 (en) 2001-10-23
DE69900162T2 (de) 2002-04-18
JP2002504524A (ja) 2002-02-12
GB9804013D0 (en) 1998-04-22
HU224611B1 (hu) 2005-11-28
PT943331E (pt) 2001-12-28
KR20010041182A (ko) 2001-05-15
AR015524A1 (es) 2001-05-02
JP4430229B2 (ja) 2010-03-10
BR9908273A (pt) 2000-10-24
IL137772A (en) 2006-04-10
ZA991489B (en) 1999-09-30
GT199900019A (es) 2000-08-04
CA2261500C (en) 2001-07-17
AU2632499A (en) 1999-09-15
CN1291886A (zh) 2001-04-18
DE69900162D1 (de) 2001-08-02
CZ302196B6 (cs) 2010-12-15
EP0943331B1 (en) 2001-06-27
UA70316C2 (uk) 2004-10-15
DK0943331T3 (da) 2001-10-15
NO20004240L (no) 2000-10-18
GR3036646T3 (en) 2001-12-31
HUP0103707A3 (en) 2004-07-28
ATE202472T1 (de) 2001-07-15
PL343021A1 (en) 2001-07-30
CA2261500A1 (en) 1999-08-25
EP0943331A2 (en) 1999-09-22
MXPA00008195A (es) 2004-11-22
ES2161085T3 (es) 2001-11-16
AU757101B2 (en) 2003-01-30
CZ20003089A3 (cs) 2000-12-13
RU2207857C2 (ru) 2003-07-10
PL197948B1 (pl) 2008-05-30
NO20004240D0 (no) 2000-08-24
CN1152718C (zh) 2004-06-09
WO1999043355A2 (en) 1999-09-02
EP0943331A3 (en) 1999-11-03

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Legal Events

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HFG4 Patent granted, date of granting

Effective date: 20051006