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HUP0102622A3 - Biphenyl derivatives, process for producing them and pharmaceutical compositions containing them - Google Patents

Biphenyl derivatives, process for producing them and pharmaceutical compositions containing them

Info

Publication number
HUP0102622A3
HUP0102622A3 HU0102622A HUP0102622A HUP0102622A3 HU P0102622 A3 HUP0102622 A3 HU P0102622A3 HU 0102622 A HU0102622 A HU 0102622A HU P0102622 A HUP0102622 A HU P0102622A HU P0102622 A3 HUP0102622 A3 HU P0102622A3
Authority
HU
Hungary
Prior art keywords
producing
pharmaceutical compositions
compositions containing
biphenyl derivatives
biphenyl
Prior art date
Application number
HU0102622A
Other languages
Hungarian (hu)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HUP0102622A2 publication Critical patent/HUP0102622A2/en
Publication of HUP0102622A3 publication Critical patent/HUP0102622A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/101,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/192Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU0102622A 1998-07-20 1999-07-08 Biphenyl derivatives, process for producing them and pharmaceutical compositions containing them HUP0102622A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98113488 1998-07-20
PCT/EP1999/004803 WO2000005225A1 (en) 1998-07-20 1999-07-08 Biphenyl derivatives

Publications (2)

Publication Number Publication Date
HUP0102622A2 HUP0102622A2 (en) 2001-12-28
HUP0102622A3 true HUP0102622A3 (en) 2002-12-28

Family

ID=8232308

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102622A HUP0102622A3 (en) 1998-07-20 1999-07-08 Biphenyl derivatives, process for producing them and pharmaceutical compositions containing them

Country Status (15)

Country Link
EP (1) EP1098892A1 (en)
JP (1) JP2002521377A (en)
KR (1) KR20010070997A (en)
CN (1) CN1309654A (en)
AR (1) AR019415A1 (en)
AU (1) AU5033899A (en)
BR (1) BR9912299A (en)
CA (1) CA2338209A1 (en)
HU (1) HUP0102622A3 (en)
ID (1) ID27846A (en)
NO (1) NO20010333D0 (en)
PL (1) PL345283A1 (en)
SK (1) SK492001A3 (en)
WO (1) WO2000005225A1 (en)
ZA (1) ZA200101379B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60131675T2 (en) * 2000-11-14 2008-11-20 Merck Patent Gmbh NEW UTILIZATION OF SUBSTANCES WITH COMBINED 5-HT1A AGONISTIC AND SEROTONINE REUPTAKE INHIBITOR ACTIVITIES
US6706724B2 (en) 2000-12-21 2004-03-16 Nitromed, Inc. Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
US7718650B2 (en) 2001-05-11 2010-05-18 Biovitrum Ab Aryl sulfonamide compounds for treating obesity
PL366619A1 (en) 2001-05-11 2005-02-07 Biovitrum Ab Novel, arylsusfonamide compounds for the treatment of obesity, type ii diabetes and cns-disorders
KR20100107509A (en) 2001-09-14 2010-10-05 9222-9129 퀘벡 인코포레이티드 Inhibitors of histone deacetylase
SE0103644D0 (en) * 2001-11-01 2001-11-01 Astrazeneca Ab Therapeutic isoquinoline compounds
PE20060574A1 (en) 2004-07-28 2006-06-24 Glaxo Group Ltd ARILPIPERAZINE SULFONAMIDE DERIVATIVES AS AGONISTS OF GROWTH HORMONE SECRETAGOG RECEPTORS (GHS)
ES2364488T3 (en) * 2004-10-14 2011-09-05 ABBOTT GMBH & CO. KG SUITABLE HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISORDERS THAT RESPOND TO THE MODULATION OF THE DOPAMINE RECEIVER.
WO2007077457A2 (en) * 2006-01-06 2007-07-12 The Royal Veterinary College Treatment of equine laminitis with 5-ht1b/ 1d antagonists
PE20080176A1 (en) 2006-03-31 2008-04-25 Glaxo Group Ltd ARILPIPERAZINE SULFONAMIDE COMPOUNDS AS AGONIST OF GROWTH HORMONE SECRETAGOGUE (GHS) RECEPTORS
CN101421234A (en) 2006-04-19 2009-04-29 艾博特股份有限两合公司 Heterocyclic aryl sulfones suitable for the treatment of conditions responsive to modulation of serotonin 5HT6 receptors
MX2008013206A (en) 2006-04-19 2008-10-22 Abbott Gmbh & Co Kg Heterocyclic compounds suitable for treating disorders that respond to modulation of the serotonin 5ht6 receptor.
ATE533744T1 (en) 2006-05-19 2011-12-15 Wyeth Llc N-BENZOYPYRROLIDINE-3-YLAMINE AS HISTAMINE-3 ANTAGONISTS
CN101679381A (en) 2007-03-23 2010-03-24 艾博特股份有限两合公司 Azetidin compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor
US8188301B2 (en) 2007-06-05 2012-05-29 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission
AU2008258549B2 (en) 2007-06-08 2013-11-14 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
CN101678019B (en) 2007-06-08 2016-03-30 詹森药业有限公司 Piperidine/piperazine derivatives
ES2483898T3 (en) 2007-06-08 2014-08-08 Janssen Pharmaceutica, N.V. Piperidine / Piperazine Derivatives
JO2972B1 (en) 2007-06-08 2016-03-15 جانسين فارماسوتيكا ان. في Piperidine/Piperazine derivatives
ES2617619T3 (en) 2008-06-05 2017-06-19 Janssen Pharmaceutica, N.V. Drug combinations comprising a DGAT inhibitor and a PPAR agonist
PT4225753T (en) * 2020-10-08 2024-08-30 Leukos Biotech S L Potent and selctive compounds as serotonin 1b receptor modulators

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9119920D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
PT533268E (en) * 1991-09-18 2002-02-28 Glaxo Group Ltd BENZANILIDA DERIVATIVES AS 5-HT1D ANTAGONISTS
GB2273930A (en) * 1992-12-30 1994-07-06 Glaxo Group Ltd Benzanilide derivatives
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
CA2338209A1 (en) 2000-02-03
NO20010333L (en) 2001-01-19
HUP0102622A2 (en) 2001-12-28
PL345283A1 (en) 2001-12-03
BR9912299A (en) 2001-11-20
ZA200101379B (en) 2002-05-20
ID27846A (en) 2001-04-26
SK492001A3 (en) 2001-08-06
CN1309654A (en) 2001-08-22
JP2002521377A (en) 2002-07-16
NO20010333D0 (en) 2001-01-19
EP1098892A1 (en) 2001-05-16
KR20010070997A (en) 2001-07-28
AU5033899A (en) 2000-02-14
WO2000005225A1 (en) 2000-02-03
AR019415A1 (en) 2002-02-20

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