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HUP0001395A3 - Novel screening methods to identify agents that selectively inhibit hepatitis c virus replication - Google Patents

Novel screening methods to identify agents that selectively inhibit hepatitis c virus replication

Info

Publication number
HUP0001395A3
HUP0001395A3 HU0001395A HUP0001395A HUP0001395A3 HU P0001395 A3 HUP0001395 A3 HU P0001395A3 HU 0001395 A HU0001395 A HU 0001395A HU P0001395 A HUP0001395 A HU P0001395A HU P0001395 A3 HUP0001395 A3 HU P0001395A3
Authority
HU
Hungary
Prior art keywords
screening methods
virus replication
selectively inhibit
identify agents
novel screening
Prior art date
Application number
HU0001395A
Other languages
English (en)
Original Assignee
Univ Washington Seattle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington Seattle filed Critical Univ Washington Seattle
Publication of HUP0001395A1 publication Critical patent/HUP0001395A1/hu
Publication of HUP0001395A3 publication Critical patent/HUP0001395A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU0001395A 1997-03-05 1998-03-05 Novel screening methods to identify agents that selectively inhibit hepatitis c virus replication HUP0001395A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3859697P 1997-03-05 1997-03-05

Publications (2)

Publication Number Publication Date
HUP0001395A1 HUP0001395A1 (en) 2000-07-28
HUP0001395A3 true HUP0001395A3 (en) 2001-09-28

Family

ID=21900807

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001395A HUP0001395A3 (en) 1997-03-05 1998-03-05 Novel screening methods to identify agents that selectively inhibit hepatitis c virus replication

Country Status (14)

Country Link
US (3) US6030785A (hu)
EP (1) EP0975809A4 (hu)
JP (1) JP2001514508A (hu)
KR (1) KR20000075983A (hu)
CN (1) CN1268980A (hu)
AU (1) AU726374B2 (hu)
CA (1) CA2283379A1 (hu)
HU (1) HUP0001395A3 (hu)
IL (1) IL131730A (hu)
NO (1) NO994295L (hu)
NZ (1) NZ337703A (hu)
PL (1) PL335721A1 (hu)
TR (1) TR199902561T2 (hu)
WO (1) WO1998039487A1 (hu)

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US6593456B1 (en) * 1996-11-06 2003-07-15 The Regents Of The University Of California Tumor necrosis factor receptor releasing enzyme
US20050191661A1 (en) * 1996-11-06 2005-09-01 Tetsuya Gatanaga Treatment of inflammatory disease by cleaving TNF receptors
PL335721A1 (en) * 1997-03-05 2000-05-08 Ribogene Novel methods of screening serving the purpose of identifying the factors of selective hepatitis c virus replication inhibition
CA2334895C (en) 1998-06-12 2016-01-19 Mount Sinai School Of Medicine Attenuated negative strand viruses with altered interferon antagonist activity for use as vaccines and pharmaceuticals
WO2001053355A1 (en) * 2000-01-24 2001-07-26 The Trustees Of Columbia University In The City Of New York An in vivo screen using chemical inducers of dimerization
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US7138376B2 (en) * 2001-09-28 2006-11-21 Idenix Pharmaceuticals, Inc. Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides
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AU2003241335A1 (en) * 2002-05-09 2003-11-11 The Regents Of The University Of California Method of analyzing ataxia-telangiectasia protein
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US20050069522A1 (en) * 2002-08-12 2005-03-31 Richard Colonno Combination pharmaceutical agents as inhibitors of HCV replication
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DE602005002673T2 (de) * 2004-04-29 2008-07-24 F. Hoffmann-La Roche Ag Nukleotidsequenzvariation im Gen NS5A als Marker
DK2497492T3 (en) * 2004-06-01 2018-11-26 Icahn School Med Mount Sinai Genetically modified swine influenza virus and its applications
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ATE474587T1 (de) * 2004-09-29 2010-08-15 Univ Tulane Inhibitoren des hepatitis-c-virus
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WO2007058384A1 (en) * 2005-11-17 2007-05-24 Osaka University Method of suppressing replication of hepatitis c virus, inhibitor of replication of the virus and method of screening for the same
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WO1994023041A2 (en) * 1993-04-02 1994-10-13 Ribogene, Inc. Method for selective inactivation of viral replication
PL335721A1 (en) 1997-03-05 2000-05-08 Ribogene Novel methods of screening serving the purpose of identifying the factors of selective hepatitis c virus replication inhibition

Also Published As

Publication number Publication date
PL335721A1 (en) 2000-05-08
US6030785A (en) 2000-02-29
NO994295L (no) 1999-11-02
NO994295D0 (no) 1999-09-03
EP0975809A4 (en) 2002-10-30
IL131730A0 (en) 2001-03-19
CN1268980A (zh) 2000-10-04
NZ337703A (en) 2001-05-25
IL131730A (en) 2004-06-20
AU726374B2 (en) 2000-11-02
CA2283379A1 (en) 1998-09-11
KR20000075983A (ko) 2000-12-26
TR199902561T2 (xx) 2000-02-21
HUP0001395A1 (en) 2000-07-28
US6326151B1 (en) 2001-12-04
US7148006B2 (en) 2006-12-12
US20020155431A1 (en) 2002-10-24
WO1998039487A1 (en) 1998-09-11
EP0975809A1 (en) 2000-02-02
AU6684098A (en) 1998-09-22
JP2001514508A (ja) 2001-09-11

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