HN2006014095A - Forma cristalina ortorrombica del maleato de asenapina - Google Patents
Forma cristalina ortorrombica del maleato de asenapinaInfo
- Publication number
- HN2006014095A HN2006014095A HN2006014095A HN2006014095A HN2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A
- Authority
- HN
- Honduras
- Prior art keywords
- orthromby
- crystal form
- asenapine maleate
- asenapine
- maleate
- Prior art date
Links
- GMDCDXMAFMEDAG-CHHFXETESA-N (S,S)-asenapine maleate Chemical compound OC(=O)\C=C/C(O)=O.O1C2=CC=CC=C2[C@H]2CN(C)C[C@@H]2C2=CC(Cl)=CC=C21 GMDCDXMAFMEDAG-CHHFXETESA-N 0.000 title 1
- 229960001615 asenapine maleate Drugs 0.000 title 1
- VSWBSWWIRNCQIJ-GJZGRUSLSA-N (R,R)-asenapine Chemical compound O1C2=CC=CC=C2[C@@H]2CN(C)C[C@H]2C2=CC(Cl)=CC=C21 VSWBSWWIRNCQIJ-GJZGRUSLSA-N 0.000 abstract 1
- 229960005245 asenapine Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
La invencion se refiere a una nueva forma cristalina de asenapina, a metodos para su preparacion y a composiciones farmaceuticas que comprenden dicha forma cristalina.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05102742 | 2005-04-07 | ||
| EP05102969 | 2005-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HN2006014095A true HN2006014095A (es) | 2010-08-19 |
Family
ID=36617328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HN2006014095A HN2006014095A (es) | 2005-04-07 | 2006-04-06 | Forma cristalina ortorrombica del maleato de asenapina |
Country Status (31)
| Country | Link |
|---|---|
| EP (2) | EP1917267B1 (es) |
| JP (1) | JP5058151B2 (es) |
| KR (1) | KR101422843B1 (es) |
| AR (1) | AR056306A1 (es) |
| AT (2) | ATE418556T1 (es) |
| AU (1) | AU2006231617B2 (es) |
| BR (1) | BRPI0609741A8 (es) |
| CA (1) | CA2603509C (es) |
| CY (2) | CY1106902T1 (es) |
| DE (2) | DE602006004463D1 (es) |
| DK (2) | DK1710245T3 (es) |
| DO (1) | DOP2006000082A (es) |
| ES (2) | ES2318742T3 (es) |
| GT (1) | GT200600135A (es) |
| HN (1) | HN2006014095A (es) |
| HR (1) | HRP20070429T3 (es) |
| IL (1) | IL186355A (es) |
| MX (1) | MX2007012445A (es) |
| MY (1) | MY137969A (es) |
| NO (1) | NO340520B1 (es) |
| NZ (1) | NZ562124A (es) |
| PE (1) | PE20061311A1 (es) |
| PL (2) | PL1710245T3 (es) |
| PT (2) | PT1917267E (es) |
| RS (1) | RS50532B (es) |
| RU (1) | RU2405786C2 (es) |
| SI (2) | SI1917267T1 (es) |
| SV (1) | SV2006002473A (es) |
| TW (1) | TWI364423B (es) |
| UY (1) | UY29459A1 (es) |
| WO (1) | WO2006106135A1 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2078024A1 (en) * | 2006-10-06 | 2009-07-15 | N.V. Organon | Amorphous asenapine and processes for preparing same |
| CA2766291C (en) * | 2009-06-24 | 2016-06-21 | Msd Oss B.V. | Injectable formulations containing asenapine and method of treatment using same |
| US8779161B2 (en) | 2010-06-18 | 2014-07-15 | Dr. Reddy's Laboratories Limited | Asenapine maleate |
| WO2012066565A2 (en) * | 2010-11-16 | 2012-05-24 | Cadila Healthcare Limited | Asenapine maleate amorphous and crystalline form and process for preparation thereof |
| EP2468750A1 (en) | 2010-12-13 | 2012-06-27 | Chemo Ibérica, S.A. | Polymorphic forms of asenapine maleate and processes for their preparation |
| WO2012123325A1 (en) | 2011-03-11 | 2012-09-20 | Medichem S.A. | NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID |
| ITMI20110734A1 (it) * | 2011-05-02 | 2012-11-03 | Olon Spa | Sali cristallini di asenapina |
| EP2524919A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids |
| EP2524921A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Salts of Asenapine |
| EP2524920A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Asenapine Hydrochloride Salt Forms |
| JP6014656B2 (ja) * | 2011-05-18 | 2016-10-25 | ラビラトリオス レスビ エス エレ | 化合物の多形体 |
| EP2709615A1 (en) | 2011-05-18 | 2014-03-26 | Laboratorios Lesvi, S.L. | Monoclinic crystalline form of asenapine maleate with a specific particle size distribution |
| EP2572703A1 (en) | 2011-09-21 | 2013-03-27 | Hexal AG | Compressed oral dosage form for asenapine maleate |
| WO2013041604A1 (en) | 2011-09-21 | 2013-03-28 | Sandoz Ag | Crystal form of asenapine maleate |
| CN104487071B (zh) * | 2012-07-26 | 2017-06-13 | 久光制药株式会社 | 贴附剂 |
| ITMI20121810A1 (it) | 2012-10-24 | 2014-04-25 | Chemo Iberica Sa | Poliformi di maleato di asenapina e processo per la loro preparazione |
| WO2014090386A1 (en) | 2012-12-11 | 2014-06-19 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Orally disintegrating tablet containing asenapine |
| WO2014127786A1 (en) | 2013-02-22 | 2014-08-28 | Zentiva, K.S. | Orally disintegrating pharmaceutical composition comprising asenapine |
| US10786520B2 (en) | 2015-09-02 | 2020-09-29 | Eloxx Pharmaceuticals Ltd. | Aminoglycoside derivatives and uses thereof in treating genetic disorders |
| CA3047354A1 (en) | 2016-12-20 | 2018-06-28 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
| WO2018115001A1 (en) | 2016-12-20 | 2018-06-28 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| WO2019002204A1 (en) | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | TRANSDERMAL THERAPEUTIC SYSTEM CONTAINING ASENAPINE AND SILICONE-TYPE ACRYLIC HYBRID POLYMER |
| US12329862B2 (en) | 2018-06-20 | 2025-06-17 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| WO2019243452A1 (en) | 2018-06-20 | 2019-12-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7605526A (nl) * | 1976-05-24 | 1977-11-28 | Akzo Nv | Nieuwe tetracyclische derivaten. |
| DE69502939T2 (de) * | 1994-03-02 | 1998-10-22 | Akzo Nobel Nv | Sublinguales oder bukkales arzneimittel |
| AU2418499A (en) * | 1997-12-19 | 1999-07-12 | Akzo Nobel N.V. | Org-5222 in the treatment of depression |
| TWI327915B (en) * | 2003-06-12 | 2010-08-01 | Organon Nv | Pharmaceutical composition comprising antipsychotic agent and use of the antipsychotic agent for treating patients with overweight |
-
2006
- 2006-04-06 WO PCT/EP2006/061408 patent/WO2006106135A1/en not_active Ceased
- 2006-04-06 UY UY29459A patent/UY29459A1/es not_active Application Discontinuation
- 2006-04-06 MY MYPI20061554A patent/MY137969A/en unknown
- 2006-04-06 AR ARP060101358A patent/AR056306A1/es not_active Application Discontinuation
- 2006-04-06 ES ES06725622T patent/ES2318742T3/es active Active
- 2006-04-06 DK DK06112332T patent/DK1710245T3/da active
- 2006-04-06 JP JP2008504776A patent/JP5058151B2/ja active Active
- 2006-04-06 GT GT200600135A patent/GT200600135A/es unknown
- 2006-04-06 AU AU2006231617A patent/AU2006231617B2/en active Active
- 2006-04-06 RS RSP-2007/0436A patent/RS50532B/sr unknown
- 2006-04-06 PL PL06112332T patent/PL1710245T3/pl unknown
- 2006-04-06 EP EP06725622A patent/EP1917267B1/en active Active
- 2006-04-06 SI SI200630190T patent/SI1917267T1/sl unknown
- 2006-04-06 EP EP06112332A patent/EP1710245B1/en active Active
- 2006-04-06 PL PL06725622T patent/PL1917267T3/pl unknown
- 2006-04-06 PT PT06725622T patent/PT1917267E/pt unknown
- 2006-04-06 PE PE2006000377A patent/PE20061311A1/es active IP Right Grant
- 2006-04-06 DO DO2006P000082A patent/DOP2006000082A/es unknown
- 2006-04-06 RU RU2007141198/04A patent/RU2405786C2/ru active Protection Beyond IP Right Term
- 2006-04-06 NZ NZ562124A patent/NZ562124A/en unknown
- 2006-04-06 ES ES06112332T patent/ES2293626T3/es active Active
- 2006-04-06 CA CA2603509A patent/CA2603509C/en active Active
- 2006-04-06 SI SI200630006T patent/SI1710245T1/sl unknown
- 2006-04-06 DE DE602006004463T patent/DE602006004463D1/de active Active
- 2006-04-06 KR KR1020077025428A patent/KR101422843B1/ko active Active
- 2006-04-06 TW TW095112187A patent/TWI364423B/zh active
- 2006-04-06 DE DE602006000080T patent/DE602006000080T2/de active Active
- 2006-04-06 HN HN2006014095A patent/HN2006014095A/es unknown
- 2006-04-06 BR BRPI0609741A patent/BRPI0609741A8/pt not_active IP Right Cessation
- 2006-04-06 PT PT06112332T patent/PT1710245E/pt unknown
- 2006-04-06 AT AT06725622T patent/ATE418556T1/de active
- 2006-04-06 MX MX2007012445A patent/MX2007012445A/es active IP Right Grant
- 2006-04-06 DK DK06725622T patent/DK1917267T3/da active
- 2006-04-06 AT AT06112332T patent/ATE370954T1/de active
- 2006-04-06 SV SV2006002473A patent/SV2006002473A/es unknown
-
2007
- 2007-09-19 HR HR20070429T patent/HRP20070429T3/xx unknown
- 2007-10-02 CY CY20071101258T patent/CY1106902T1/el unknown
- 2007-10-07 IL IL186355A patent/IL186355A/en active IP Right Grant
- 2007-10-10 NO NO20075142A patent/NO340520B1/no unknown
-
2009
- 2009-01-30 CY CY20091100111T patent/CY1108742T1/el unknown
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