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HK173896A - Carrier-bound multicomponent detection system for the colorimetric determination of esterolytic or/and proteolytic substances of body fluids - Google Patents

Carrier-bound multicomponent detection system for the colorimetric determination of esterolytic or/and proteolytic substances of body fluids Download PDF

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Publication number
HK173896A
HK173896A HK173896A HK173896A HK173896A HK 173896 A HK173896 A HK 173896A HK 173896 A HK173896 A HK 173896A HK 173896 A HK173896 A HK 173896A HK 173896 A HK173896 A HK 173896A
Authority
HK
Hong Kong
Prior art keywords
steamed steamed
carrier
detection system
component
esterolytically
Prior art date
Application number
HK173896A
Other languages
German (de)
English (en)
Inventor
Dr Backhaus Juergen
Dr Mangold Dieter
Dr Knappe Wolfgang-Reinhold
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6352593&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK173896(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of HK173896A publication Critical patent/HK173896A/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/50—Indoles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/70—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Claims (3)

1. Système de détection à plusieurs composants, lié à un support, pour la détermination colorimétrique de substances ayant une activité estérolytique et/ou protéolytique, contenues dans des fluides corporels, comportant un composant pouvant être coupé par estérolyse et/ou protéolyse, et un composant transformant le produit de cette réaction, en réagissant avec lui, en une substance colorée, caractérisé en ce que les composants sont disposés sur des supports de réactifs différents, permettant un échange de liquide entre eux.
2. Système de détection selon la revendication 1, caractérisé en ce que comme composant on applique, sur des supports de réactif séparés, au moins un ester pouvant être coupé par estérolyse et/ou protéolyse, et au moins un sel de diazonium.
3. Procédé pour la détection de leucocytes dans l'urine, consistant à :
- mettre en contact l'urine avec au moins un composant pouvant être coupé par estérolyse et/ou protéolyse, et au moins un sel de diazonium, et
- faire réagir le composant coupé par les leucocytes avec le sel de diazonium, caractérisé en ce que le sel de diazonium est dissous au moins partiellement à partir d'un premier support de réactif et le composant pouvant être coupé est dissous au moins partiellement à partir d'un second support de réactif, et que les composants sont mélangés entre eux.
HK173896A 1988-04-22 1996-09-12 Carrier-bound multicomponent detection system for the colorimetric determination of esterolytic or/and proteolytic substances of body fluids HK173896A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3813503A DE3813503A1 (de) 1988-04-22 1988-04-22 Traegergebundenes mehrkomponentiges nachweissystem zur kolorimetrischen bestimmung esterolytisch oder/und proteolytisch aktiver inhaltsstoffe von koerperfluessigkeiten

Publications (1)

Publication Number Publication Date
HK173896A true HK173896A (en) 1996-09-20

Family

ID=6352593

Family Applications (1)

Application Number Title Priority Date Filing Date
HK173896A HK173896A (en) 1988-04-22 1996-09-12 Carrier-bound multicomponent detection system for the colorimetric determination of esterolytic or/and proteolytic substances of body fluids

Country Status (9)

Country Link
US (1) US5015572A (fr)
EP (1) EP0340511B2 (fr)
JP (1) JPH0724599B2 (fr)
KR (1) KR910008570B1 (fr)
AT (1) ATE85127T1 (fr)
DE (2) DE3813503A1 (fr)
ES (1) ES2053853T5 (fr)
GR (2) GR3007606T3 (fr)
HK (1) HK173896A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69512263T2 (de) * 1994-11-07 2000-05-31 Litmus Concepts, Inc. Assay für prolin-iminopeptidase und andere hydrolytische aktivitäten
US5716831A (en) * 1995-05-24 1998-02-10 Board Of Trustees Operating Michigan State University Method and test kit for detecting insecticide resistance
US6528652B1 (en) * 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
JP4714565B2 (ja) 2005-11-17 2011-06-29 パイオニア株式会社 スピーカ装置
JP2014011974A (ja) * 2012-07-04 2014-01-23 Sony Corp 化学反応用マイクロチップ及びその製造方法
EP3848708A1 (fr) 2020-01-13 2021-07-14 Roche Diagnostics GmbH Formulation de réactif pour bande d'essai de leucocytes

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3017721A1 (de) * 1980-05-09 1981-11-26 Boehringer Mannheim Gmbh, 6800 Mannheim Mittel zum nachweis esterolytischer und/oder proteolytischer enzyme und dafuer geeignete substrate
JPS57144996A (en) * 1981-02-27 1982-09-07 Fuji Photo Film Co Ltd Film for quantitative analysis
DE3118381A1 (de) * 1981-05-09 1982-11-25 Boehringer Mannheim Gmbh, 6800 Mannheim Mehrschichtiges testmittel zum nachweis einer komponente einer fluessigen probe
JPS57208997A (en) * 1981-06-17 1982-12-22 Fuji Photo Film Co Ltd Liquid analyzing material for oxidase enzyme reaction system
JPS57208998A (en) * 1981-06-17 1982-12-22 Fuji Photo Film Co Ltd Multi-layered analytical film for determination of transaminase
DE3332144A1 (de) * 1982-09-06 1984-03-08 Konishiroku Photo Industry Co., Ltd., Tokyo Analytisches element
US4637979A (en) * 1984-04-06 1987-01-20 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent
DE3413078A1 (de) * 1984-04-06 1985-10-24 Miles Laboratories, Inc., Elkhart, Ind. Chromogene aminosaeure- und peptidester, verfahren zu deren herstellung, verwendung dieser verbindungen in analysenverfahren sowie mittel zum nachweis esterolytischer und/oder proteolytischer enzyme
DE3413119A1 (de) * 1984-04-06 1985-10-24 Miles Laboratories, Inc., Elkhart, Ind. Analysenverfahren und mittel zum nachweis esterolytischer und/oder proteolytischer enzyme
JPS60222770A (ja) * 1984-04-19 1985-11-07 Fuji Photo Film Co Ltd 一体型多層分析要素
JPS62182652A (ja) * 1985-06-20 1987-08-11 Fuji Photo Film Co Ltd 酵素活性測定用乾式分析要素
DE3616496A1 (de) * 1986-05-16 1987-11-19 Boehringer Mannheim Gmbh Analyseelement zur bestimmung von gerinnungsparametern
JPS63219397A (ja) * 1986-05-28 1988-09-13 Fuji Photo Film Co Ltd 酵素活性測定用乾式分析要素

Also Published As

Publication number Publication date
JPH0724599B2 (ja) 1995-03-22
KR910008570B1 (ko) 1991-10-19
EP0340511B2 (fr) 1997-01-29
ES2053853T5 (es) 1997-06-01
DE58903378D1 (de) 1993-03-11
ATE85127T1 (de) 1993-02-15
US5015572A (en) 1991-05-14
EP0340511B1 (fr) 1993-01-27
ES2053853T3 (es) 1994-08-01
GR3007606T3 (en) 1993-08-31
JPH0213398A (ja) 1990-01-17
EP0340511A1 (fr) 1989-11-08
DE3813503A1 (de) 1989-11-02
KR890016386A (ko) 1989-11-29
GR3022696T3 (en) 1997-05-31

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Effective date: 20090413