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HK1228388B - 作为dna-pk抑制剂的(s)-n-甲基-8-(1-((2'-甲基-[4，5'-联嘧啶]-6-基)氨基)丙-2-基)喹啉-4-甲酰胺及其氘化衍生物的共晶 - Google Patents

作为dna-pk抑制剂的(s)-n-甲基-8-(1-((2'-甲基-[4，5'-联嘧啶]-6-基)氨基)丙-2-基)喹啉-4-甲酰胺及其氘化衍生物的共晶 Download PDF

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Publication number
HK1228388B
HK1228388B HK17101924.0A HK17101924A HK1228388B HK 1228388 B HK1228388 B HK 1228388B HK 17101924 A HK17101924 A HK 17101924A HK 1228388 B HK1228388 B HK 1228388B
Authority
HK
Hong Kong
Prior art keywords
compound
crystal
methyl
adipic acid
cancer
Prior art date
Application number
HK17101924.0A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1228388A1 (zh
Inventor
Kwame Wiredu NTI-ADDAE
Simon Adam O'NEIL
Yuegang Zhang
Praveen Mudunuri
John Gregg Van Alsten
Bin Song
Kathy Stavropoulos
Mark STROHMEIER
Michael Waldo
Mettachit Navamal
Irina Nikolaevna Kadiyala
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of HK1228388A1 publication Critical patent/HK1228388A1/zh
Publication of HK1228388B publication Critical patent/HK1228388B/zh

Links

HK17101924.0A 2013-10-17 2014-10-17 作为dna-pk抑制剂的(s)-n-甲基-8-(1-((2'-甲基-[4，5'-联嘧啶]-6-基)氨基)丙-2-基)喹啉-4-甲酰胺及其氘化衍生物的共晶 HK1228388B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61/892002 2013-10-17

Publications (2)

Publication Number Publication Date
HK1228388A1 HK1228388A1 (zh) 2017-11-03
HK1228388B true HK1228388B (zh) 2019-06-06

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