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HK1219959B - 三型金属蛋白酶(timp-3)组织抑制剂的变体、组合物和方法 - Google Patents

三型金属蛋白酶(timp-3)组织抑制剂的变体、组合物和方法 Download PDF

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Publication number
HK1219959B
HK1219959B HK16108002.1A HK16108002A HK1219959B HK 1219959 B HK1219959 B HK 1219959B HK 16108002 A HK16108002 A HK 16108002A HK 1219959 B HK1219959 B HK 1219959B
Authority
HK
Hong Kong
Prior art keywords
timp
seq
mutein
cell
polypeptide
Prior art date
Application number
HK16108002.1A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1219959A1 (zh
Inventor
Jeonghoon Sun
Jason Charles O'NEILL
Randal R. Ketchem
Randy Ira Hecht
Edward J. BELOUSKI
Mark Leo Michaels
Original Assignee
美国安进公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美国安进公司 filed Critical 美国安进公司
Priority claimed from PCT/US2014/026811 external-priority patent/WO2014152012A2/en
Publication of HK1219959A1 publication Critical patent/HK1219959A1/zh
Publication of HK1219959B publication Critical patent/HK1219959B/zh

Links

HK16108002.1A 2013-03-14 2014-03-13 三型金属蛋白酶(timp-3)组织抑制剂的变体、组合物和方法 HK1219959B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201361782613P 2013-03-14 2013-03-14
US61/782,613 2013-03-14
US201361798160P 2013-03-15 2013-03-15
US61/798,160 2013-03-15
US201361802988P 2013-03-18 2013-03-18
US61/802,988 2013-03-18
US201461940673P 2014-02-17 2014-02-17
US61/940,673 2014-02-17
PCT/US2014/026811 WO2014152012A2 (en) 2013-03-14 2014-03-13 Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods

Publications (2)

Publication Number Publication Date
HK1219959A1 HK1219959A1 (zh) 2017-04-21
HK1219959B true HK1219959B (zh) 2024-02-02

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HK1219959B (zh) 三型金属蛋白酶(timp-3)组织抑制剂的变体、组合物和方法