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HK1218139A1 - Cell compositions derived from dedifferentiated reprogrammed cells - Google Patents

Cell compositions derived from dedifferentiated reprogrammed cells Download PDF

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Publication number
HK1218139A1
HK1218139A1 HK16106057.9A HK16106057A HK1218139A1 HK 1218139 A1 HK1218139 A1 HK 1218139A1 HK 16106057 A HK16106057 A HK 16106057A HK 1218139 A1 HK1218139 A1 HK 1218139A1
Authority
HK
Hong Kong
Prior art keywords
cell compositions
reprogrammed cells
compositions derived
cell culture
dedifferentiated reprogrammed
Prior art date
Application number
HK16106057.9A
Other languages
Chinese (zh)
Inventor
Alan D. Agulnick
Olivia Kelly
Yuki OHI
Allan Robins
Thomas Schultz
Original Assignee
Viacyte, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/761,078 external-priority patent/US9109245B2/en
Application filed by Viacyte, Inc. filed Critical Viacyte, Inc.
Publication of HK1218139A1 publication Critical patent/HK1218139A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Disclosed herein are cell culture compositions, for example, pancreatic cell culture compositions, derived from dedifferentiated human reprogrammed pluripotent stem cells, such as induced pluripotent stem (iPS) cells, and methods for producing and using such cell culture compositions.
HK16106057.9A 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells HK1218139A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/761,078 2013-02-06
US13/761,078 US9109245B2 (en) 2009-04-22 2013-02-06 Cell compositions derived from dedifferentiated reprogrammed cells
PCT/US2014/015156 WO2014124172A1 (en) 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells

Publications (1)

Publication Number Publication Date
HK1218139A1 true HK1218139A1 (en) 2017-02-03

Family

ID=50239931

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16106057.9A HK1218139A1 (en) 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells

Country Status (8)

Country Link
EP (1) EP2954045A1 (en)
JP (5) JP6517702B2 (en)
AU (4) AU2014214879A1 (en)
CA (2) CA3212301A1 (en)
HK (1) HK1218139A1 (en)
IL (5) IL311689B2 (en)
RU (2) RU2754089C2 (en)
WO (1) WO2014124172A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9109245B2 (en) 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
CN106795487B (en) 2014-08-04 2021-11-19 武田药品工业株式会社 Method for proliferating pancreatic progenitor cells
MA45479A (en) * 2016-04-14 2019-02-20 Janssen Biotech Inc DIFFERENTIATION OF PLURIPOTENT STEM CELLS IN ENDODERMAL CELLS OF MIDDLE INTESTINE
JP7367951B2 (en) * 2016-05-18 2023-10-24 慶應義塾 Cell culture medium for organoid culture
EP4194549A1 (en) 2017-01-27 2023-06-14 Kaneka Corporation Endodermal cell population, and method for producing cell population of any of three germ layers from pluripotent cell
IL313825B2 (en) 2017-06-14 2025-07-01 Vertex Pharma Devices and methods for delivering therapeutics
EP4488363A3 (en) * 2017-07-21 2025-03-26 Vertex Pharmaceuticals Incorporated Re-aggregation of stem cell-derived pancreatic beta cells
TW202014514A (en) * 2018-08-03 2020-04-16 國立大學法人京都大學 Cell manufacturing
SG11202102748WA (en) * 2018-09-19 2021-04-29 Takeda Pharmaceuticals Co Insulin-producing cells
CN114173837A (en) 2019-05-31 2022-03-11 W.L.戈尔及同仁股份有限公司 Biocompatible film composite
JP7555975B2 (en) 2019-05-31 2024-09-25 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド Biocompatible Membrane Composites
CA3139585C (en) 2019-05-31 2024-01-23 W. L. Gore & Associates, Inc. A biocompatible membrane composite
JP7328362B2 (en) 2019-05-31 2023-08-16 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド Cell encapsulation device with controlled oxygen diffusion distance
AU2021319209A1 (en) 2020-07-31 2023-03-02 Vertex Pharmaceuticals Incorporated Differentiation of pancreatic endocrine cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE397959T1 (en) * 1999-04-06 2008-07-15 Genentech Inc USE OF ERBB RECEPTOR LIGANDS TO TREAT DIABETES
US6759039B2 (en) * 2000-06-30 2004-07-06 Amcyte, Inc. Culturing pancreatic stem cells having a specified, intermediate stage of development
JP2005503759A (en) * 2001-01-24 2005-02-10 アメリカ合衆国 Differentiation of stem cells into pancreatic endocrine cells
SG169324A1 (en) * 2005-10-14 2011-03-30 Univ Minnesota Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
WO2007143193A1 (en) * 2006-06-02 2007-12-13 University Of Georgia Research Foundation, Inc. Pancreatic and liver endoderm cells and tissue by differentiation of definitive endoderm cells obtained from human embryonic stems
EP2356227B1 (en) 2008-11-14 2018-03-28 Viacyte, Inc. Encapsulation of pancreatic cells derived from human pluripotent stem cells
EP3904505A1 (en) * 2009-04-22 2021-11-03 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
US9109245B2 (en) * 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
SG175367A1 (en) * 2009-04-27 2011-11-28 Viacyte Inc Small molecules supporting pluripotent cell growth and methods thereof

Also Published As

Publication number Publication date
AU2022200075B2 (en) 2023-02-02
IL311689B1 (en) 2025-08-01
AU2014214879A1 (en) 2015-07-30
CA3212301A1 (en) 2014-08-14
JP2023017838A (en) 2023-02-07
IL239953A0 (en) 2015-08-31
IL290717A (en) 2022-04-01
AU2023202507B2 (en) 2025-12-04
AU2022200075A1 (en) 2022-02-03
EP2954045A1 (en) 2015-12-16
RU2675928C2 (en) 2018-12-25
AU2019201314B2 (en) 2021-10-14
JP2020178694A (en) 2020-11-05
RU2018144412A (en) 2019-03-25
IL239953B (en) 2021-05-31
JP7550830B2 (en) 2024-09-13
RU2018144412A3 (en) 2020-02-14
AU2022200075C1 (en) 2023-07-06
JP7250731B2 (en) 2023-04-03
IL311689B2 (en) 2025-12-01
IL311689A (en) 2024-05-01
CA2898431A1 (en) 2014-08-14
IL290717B1 (en) 2024-06-01
JP6517702B2 (en) 2019-05-22
JP2019146578A (en) 2019-09-05
AU2019201314A1 (en) 2019-03-14
AU2023202507A1 (en) 2023-05-11
RU2015131279A (en) 2017-03-13
IL283088B (en) 2022-04-01
JP2025000625A (en) 2025-01-07
RU2754089C2 (en) 2021-08-26
IL321825A (en) 2025-08-01
JP6721752B2 (en) 2020-07-15
WO2014124172A1 (en) 2014-08-14
IL290717B2 (en) 2024-10-01
CA2898431C (en) 2023-10-17
JP2016506736A (en) 2016-03-07
IL283088A (en) 2021-06-30

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