[go: up one dir, main page]

HK1212889A1 - Sustained release oral dosage forms comprising low melting propionic acid derivative particles - Google Patents

Sustained release oral dosage forms comprising low melting propionic acid derivative particles Download PDF

Info

Publication number
HK1212889A1
HK1212889A1 HK16100785.1A HK16100785A HK1212889A1 HK 1212889 A1 HK1212889 A1 HK 1212889A1 HK 16100785 A HK16100785 A HK 16100785A HK 1212889 A1 HK1212889 A1 HK 1212889A1
Authority
HK
Hong Kong
Prior art keywords
dosage forms
propionic acid
acid derivative
low melting
derivative particles
Prior art date
Application number
HK16100785.1A
Other languages
Chinese (zh)
Inventor
Saumitra Bagchi
Murali K. VUPPALA
Original Assignee
Mcneil-Ppc, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil-Ppc, Inc. filed Critical Mcneil-Ppc, Inc.
Publication of HK1212889A1 publication Critical patent/HK1212889A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Low melting propionic acid derivative particles that are free flowing and have significantly reduced or eliminated throat burn are disclosed. A method of manufacturing the low melting propionic acid derivative particles; dosage forms containing the low melting propionic acid derivative particles; methods of manufacturing the dosage forms; and methods of treatment using the dosage forms are also disclosed.
HK16100785.1A 2012-09-18 2013-09-16 Sustained release oral dosage forms comprising low melting propionic acid derivative particles HK1212889A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261702412P 2012-09-18 2012-09-18
US201261702412P 2012-09-18
PCT/US2013/059929 WO2014047005A1 (en) 2012-09-18 2013-09-16 Sustained release oral dosage forms comprising low melting propionic acid derivative particles

Publications (1)

Publication Number Publication Date
HK1212889A1 true HK1212889A1 (en) 2016-06-24

Family

ID=49231644

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16100785.1A HK1212889A1 (en) 2012-09-18 2013-09-16 Sustained release oral dosage forms comprising low melting propionic acid derivative particles

Country Status (9)

Country Link
US (1) US20140079796A1 (en)
EP (1) EP2897646A1 (en)
CN (1) CN104640571A (en)
AU (2) AU2013318360A1 (en)
BR (1) BR112015005968A2 (en)
CA (1) CA2884270A1 (en)
HK (1) HK1212889A1 (en)
RU (1) RU2015114433A (en)
WO (1) WO2014047005A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112826798B (en) * 2019-11-25 2023-04-07 上海博志研新药物技术有限公司 Ibuprofen pharmaceutical composition, preparation method and application

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
DE3440288C2 (en) 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmaceutical preparation containing ibuprofen and process for its preparation
US4923898A (en) 1984-12-26 1990-05-08 Analgesic Associates Analgesic, anti-inflammatory and skeletal muscle relaxant compositions comprising non-steroidal anti-inflammatory drugs and musculoskeletal relaxants and methods of using same
US4873231A (en) 1986-04-08 1989-10-10 Smith Walton J Decreasing the toxicity of an ibuprofen salt
CA2063141C (en) 1989-08-04 1997-03-04 Edward J. Roche Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
IT1246383B (en) 1990-04-17 1994-11-18 Eurand Int METHOD FOR MASKING THE TASTE OF DRUGS
CA2061520C (en) 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
US5405617A (en) 1991-11-07 1995-04-11 Mcneil-Ppc, Inc. Aliphatic or fatty acid esters as a solventless carrier for pharmaceuticals
CA2143439A1 (en) 1992-09-03 1994-03-17 Seang H. Yiv Taste-masking pharmaceutical compostiions and methods for making the same
IT1264855B1 (en) 1993-06-21 1996-10-17 Zambon Spa PHARMACEUTICAL COMPOSITIONS CONTAINING S (+) - 2- (4-ISOBUTYLPHENYL) PROPIONIC ACID SALTS WITH BASIC AMINO ACIDS
US5866162A (en) * 1993-08-10 1999-02-02 Smithkline Beecham P.L.C. Pharmaceutical composition containing a drug/β-cyclodextrin complex in combination with an acid-base couple
GB9316580D0 (en) * 1993-08-10 1993-09-29 Smithkline Beecham Plc Pharmaceutical composition
ZA945944B (en) 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
TW442287B (en) 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
US6692767B2 (en) * 1997-09-19 2004-02-17 Shire Laboratories Inc. Solid solution beadlet
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US6117452A (en) 1998-08-12 2000-09-12 Fuisz Technologies Ltd. Fatty ester combinations
FR2811912B1 (en) 2000-07-21 2003-02-07 Gattefosse Ets Sa PROCESS FOR COATING SOLID PARTICLES WITH A HEAT-MELTING AGENT, AND SOLID PARTICLES THUS COATED
GB0113841D0 (en) 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US20030232097A1 (en) * 2002-06-17 2003-12-18 Strides Inc. Oily wax matrix suspension formulation comprising ibuprofen free acid and potassium salt of ibuprofen
US7423004B2 (en) * 2003-01-31 2008-09-09 Smithkline Beecham Corporation Solid dispersion compositions
EP2094248A2 (en) * 2006-10-25 2009-09-02 McNeil-PPC, Inc. Ibuprofen composition
EP1972336A1 (en) * 2007-03-19 2008-09-24 LEK Pharmaceuticals D.D. Hot-melt micropellets

Also Published As

Publication number Publication date
WO2014047005A1 (en) 2014-03-27
BR112015005968A2 (en) 2017-07-04
CA2884270A1 (en) 2014-03-27
AU2013318360A1 (en) 2015-03-26
EP2897646A1 (en) 2015-07-29
AU2018202909A1 (en) 2018-05-17
US20140079796A1 (en) 2014-03-20
CN104640571A (en) 2015-05-20
RU2015114433A (en) 2016-11-10

Similar Documents

Publication Publication Date Title
ZA201309617B (en) Method of administration of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and the salts thereof in the treatment of schizophrenia
WO2012083017A3 (en) Controlled release oral dosage forms of poorly soluble drugs and uses thereof
EP3003281A4 (en) Novel core-shell nanoparticles for oral drug delivery
WO2012104655A3 (en) Compostions and methods for treating chronic inflammation and inflammatory diseases
PT2604610T (en) Phthalazinone ketone derivative, preparation method thereof, and pharmaceutical use thereof
PT2726141T (en) Device, system and methods for the oral delivery of therapeutic compounds
HUE041553T2 (en) Methods and compositions for the treatment of monogenic diseases
WO2012129341A3 (en) Disease detection in plants
PT2563316T (en) Methods, articles and kits for allergic desensitization via the oral mucosa
EP2844185B8 (en) Method for producing dentures and articulator for carrying out the method
AP2014007804A0 (en) Compositions and methods for the treatment of hepatic diseases and disorders.
EP3069720A4 (en) Pharmaceutical composition containing glutarimide derivatives, and application thereof for treating eosinophilic diseases
EP2672981A1 (en) Multiparticulate l-menthol formulations and related methods
EP2985282A4 (en) Glutarimide derivatives, use thereof, pharmaceutical composition based thereon and methods for producing glutarimide derivatives
WO2012016683A3 (en) Oral dosage form of pregabalin
WO2014044794A3 (en) Pharmaceutical composition
IL232970A0 (en) Oral spray formulations and method for administration thereof
EP2671846A4 (en) Noble metal-oxide joined nanoparticles and method for high-purity production of the same
EP2709455A4 (en) Processes for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives
HK1212886A1 (en) Low melting propionic acid derivative particles for use in oral dosage forms
HK1216721A1 (en) Uses and methods for the treatment of liver diseases or conditions
EP2698150A4 (en) Oral solid preparation of compound antituberculosis drug and preparation method thereof
HK1212889A1 (en) Sustained release oral dosage forms comprising low melting propionic acid derivative particles
EP3187187A4 (en) Adsorbent for oral administration, therapeutic agent for renal diseases and therapeutic agent for hepatic diseases
PL399613A1 (en) Derivatives of 1-aminalkanephosphonic acid diaryl esters, process for the preparation of derivative of 1-aminalkanephosphonic acid diaryl esters and their use