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HK1210011B - Association of n-{[(7s)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl)-n-methyl-3-oxo-1-propanamine and perindopril - Google Patents

Association of n-{[(7s)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl)-n-methyl-3-oxo-1-propanamine and perindopril Download PDF

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Publication number
HK1210011B
HK1210011B HK15110660.1A HK15110660A HK1210011B HK 1210011 B HK1210011 B HK 1210011B HK 15110660 A HK15110660 A HK 15110660A HK 1210011 B HK1210011 B HK 1210011B
Authority
HK
Hong Kong
Prior art keywords
methyl
perindopril
dimethoxybicyclo
octa
dimethoxy
Prior art date
Application number
HK15110660.1A
Other languages
English (en)
French (fr)
Chinese (zh)
Other versions
HK1210011A1 (zh
Inventor
Christian Thuillez
Paulus Mulder
Jean-Paul Vilaine
Marie-Dominique Fratacci
Guy Lerebours-Pigeonniere
Luc Feldmann
Jérôme Roussel
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR1002525A external-priority patent/FR2961105B1/fr
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of HK1210011A1 publication Critical patent/HK1210011A1/zh
Publication of HK1210011B publication Critical patent/HK1210011B/xx

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Claims (3)

  1. Kombination aus N-{[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxo-1-propanamin oder eines seiner Additionssalze mit einer pharmazeutisch annehmbaren Säure, deren Hydrate oder Kristallformen, und Perindopril oder eines seiner Additionssalze mit einer pharmazeutisch annehmbaren Base, deren Hydrate oder Kristallformen.
  2. Kombination nach Anspruch 1, dadurch gekennzeichnet, dass N-{[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxo-1-propanamin in Form des Hydrochlorids oder Fumarats oder eines ihrer Hydrate oder Kristallformen vorliegt.
  3. Kombination nach einem der Ansprüche 1 oder 2, dadurch gekennzeichnet, dass Perindopril in Form des tert.-Butylamin- oder Argininsalzes oder eines ihrer Hydrate oder Kristallformen vorliegt.
HK15110660.1A 2010-06-15 2015-10-28 Association of n-{[(7s)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3h-3-benzazepin-3-yl)-n-methyl-3-oxo-1-propanamine and perindopril HK1210011B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1002525 2010-06-15
FR1002525A FR2961105B1 (fr) 2010-06-15 2010-06-15 Utilisation de l'association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion de l'angiotensine pour le traitement de l'insuffisance cardiaque

Publications (2)

Publication Number Publication Date
HK1210011A1 HK1210011A1 (zh) 2016-04-15
HK1210011B true HK1210011B (en) 2017-02-17

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