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HK1201207A1 - Acc抑制劑和其用途 - Google Patents

Acc抑制劑和其用途 Download PDF

Info

Publication number
HK1201207A1
HK1201207A1 HK15101877.9A HK15101877A HK1201207A1 HK 1201207 A1 HK1201207 A1 HK 1201207A1 HK 15101877 A HK15101877 A HK 15101877A HK 1201207 A1 HK1201207 A1 HK 1201207A1
Authority
HK
Hong Kong
Prior art keywords
compound
nitrogen
sulfur
oxygen
independently selected
Prior art date
Application number
HK15101877.9A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1201207B (zh
Inventor
Geraldine C. Harriman
Craig E. Masse
James Harwood
Sathesh Bhat
Jeremy Robert Greenwood
Original Assignee
Gilead Apollo, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Apollo, Llc filed Critical Gilead Apollo, Llc
Publication of HK1201207A1 publication Critical patent/HK1201207A1/zh
Publication of HK1201207B publication Critical patent/HK1201207B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK15101877.9A 2011-11-11 2012-11-09 Acc抑制劑和其用途 HK1201207B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161559023P 2011-11-11 2011-11-11
US61/559,023 2011-11-11
US201261615092P 2012-03-23 2012-03-23
US61/615,092 2012-03-23
US201261651878P 2012-05-25 2012-05-25
US61/651,878 2012-05-25
US201261675513P 2012-07-25 2012-07-25
US61/675,513 2012-07-25
PCT/US2012/064528 WO2013071169A1 (en) 2011-11-11 2012-11-09 Acc inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
HK1201207A1 true HK1201207A1 (zh) 2015-08-28
HK1201207B HK1201207B (zh) 2018-06-22

Family

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Also Published As

Publication number Publication date
KR20190041027A (ko) 2019-04-19
ES2912574T3 (es) 2022-05-26
CN109970760B (zh) 2022-04-26
AU2012335088A1 (en) 2014-05-29
EP3329919A1 (en) 2018-06-06
DK2776038T3 (en) 2018-04-23
PL3329919T3 (pl) 2020-05-18
EP3329919B1 (en) 2019-11-06
RS57157B1 (sr) 2018-07-31
MX370976B (es) 2020-01-10
JP6114297B2 (ja) 2017-04-12
TW201720831A (zh) 2017-06-16
JP2018052989A (ja) 2018-04-05
TWI582095B (zh) 2017-05-11
CY1120224T1 (el) 2018-12-12
UA114901C2 (uk) 2017-08-28
MX344490B (es) 2016-12-16
CN106905346B (zh) 2019-05-28
NZ738735A (en) 2019-08-30
TW201930310A (zh) 2019-08-01
EP2776038A4 (en) 2015-04-01
US9944655B2 (en) 2018-04-17
CN106905346A (zh) 2017-06-30
NZ723933A (en) 2018-03-23
SMT201800191T1 (it) 2018-05-02
WO2013071169A1 (en) 2013-05-16
JP2014533281A (ja) 2014-12-11
TW201831492A (zh) 2018-09-01
KR20140106554A (ko) 2014-09-03
PL2776038T3 (pl) 2018-06-29
AU2019253834B2 (en) 2021-04-29
ES2665580T3 (es) 2018-04-26
ZA201704192B (en) 2021-10-27
US20190016732A1 (en) 2019-01-17
HRP20180534T1 (hr) 2018-05-04
MX2014005693A (es) 2014-11-26
SI3329919T1 (sl) 2020-02-28
MX390746B (es) 2025-03-21
TW201350489A (zh) 2013-12-16
PL3628320T3 (pl) 2022-07-25
ZA201704173B (en) 2021-08-25
ZA201403633B (en) 2021-10-27
BR112014011351A2 (pt) 2017-06-06
KR102060290B1 (ko) 2019-12-27
BR122019026836B1 (pt) 2021-02-23
LT2776038T (lt) 2018-04-25
JP2017114910A (ja) 2017-06-29
CA2855372A1 (en) 2013-05-16
US8969557B2 (en) 2015-03-03
JP6276442B2 (ja) 2018-02-07
TWI655193B (zh) 2019-04-01
LT3329919T (lt) 2020-02-10
MX2020000331A (es) 2022-03-16
HUE037444T2 (hu) 2018-09-28
EA033598B1 (ru) 2019-11-07
ES2767956T3 (es) 2020-06-19
KR20190143473A (ko) 2019-12-30
EA030264B1 (ru) 2018-07-31
US20130123231A1 (en) 2013-05-16
NZ624819A (en) 2016-10-28
EP2776038B1 (en) 2018-01-10
CL2014001241A1 (es) 2014-11-28
BR112014011351B1 (pt) 2021-02-17
CN104105485A (zh) 2014-10-15
KR102033806B1 (ko) 2019-10-17
CA2855372C (en) 2022-03-22
PT2776038T (pt) 2018-04-18
DK3329919T3 (da) 2019-12-09
EA201692104A1 (ru) 2017-08-31
TWI701253B (zh) 2020-08-11
SI2776038T1 (en) 2018-06-29
HUE047049T2 (hu) 2020-04-28
EP3628320B1 (en) 2022-03-16
EP3628320A1 (en) 2020-04-01
AU2012335088B2 (en) 2017-08-24
TWI612050B (zh) 2018-01-21
EP2776038A1 (en) 2014-09-17
AU2019253834A1 (en) 2019-11-14
PT3329919T (pt) 2020-01-20
UA123760C2 (uk) 2021-06-02
CN109970760A (zh) 2019-07-05
US20150203510A1 (en) 2015-07-23
EP3329919A8 (en) 2020-10-07
CY1122657T1 (el) 2021-03-12
AU2017265088B2 (en) 2019-08-08
KR102172902B1 (ko) 2020-11-02
CN104105485B (zh) 2017-04-12
JP2019147847A (ja) 2019-09-05
JP6756014B2 (ja) 2020-09-16
AU2017265088A1 (en) 2017-12-14
US20200102323A1 (en) 2020-04-02
US9453026B2 (en) 2016-09-27
HRP20192202T1 (hr) 2020-03-06
JP6543358B2 (ja) 2019-07-10
EA201490826A1 (ru) 2015-01-30
US20160297834A1 (en) 2016-10-13
US10472374B2 (en) 2019-11-12

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