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HK1248128B - Mifepristone and octreotide for use in the treatment of cushing's syndrome in a patient having an adrenocorticotropic hormone (acth)-secreting pancreatic neuroendocrine tumor - Google Patents

Mifepristone and octreotide for use in the treatment of cushing's syndrome in a patient having an adrenocorticotropic hormone (acth)-secreting pancreatic neuroendocrine tumor Download PDF

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Publication number
HK1248128B
HK1248128B HK18107713.1A HK18107713A HK1248128B HK 1248128 B HK1248128 B HK 1248128B HK 18107713 A HK18107713 A HK 18107713A HK 1248128 B HK1248128 B HK 1248128B
Authority
HK
Hong Kong
Prior art keywords
acth
octreotide
somatostatin
cases
secreting
Prior art date
Application number
HK18107713.1A
Other languages
German (de)
English (en)
Chinese (zh)
Other versions
HK1248128A1 (en
Inventor
Andreas G. MORAITIS
Joseph K. Belanoff
Original Assignee
Corcept Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corcept Therapeutics, Inc. filed Critical Corcept Therapeutics, Inc.
Priority claimed from PCT/US2016/019646 external-priority patent/WO2016140867A1/fr
Publication of HK1248128A1 publication Critical patent/HK1248128A1/en
Publication of HK1248128B publication Critical patent/HK1248128B/en

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Claims (5)

  1. Mifépristone et octréotide destinés à être utilisés dans le traitement du syndrome de Cushing chez un patient comportant une tumeur neuroendocrine pancréatique sécrétant l'hormone adrénocorticotrope (ACTH), l'octréotide étant administré en premier, suivi d'une deuxième administration de mifépristone.
  2. Mifépristone et octréotide destinés à être utilisés selon la revendication 1, le sujet souffrant de la maladie de Cushing ou d'un syndrome ACTH ectopique.
  3. Mifépristone et octréotide destinés à être utilisés selon la revendication 1, l'octréotide devant être administré dans une formulation à libération prolongée.
  4. Mifépristone et octréotide destinés à être utilisés selon la revendication 1, l'octréotide comprenant un radionucléide thérapeutique.
  5. Mifépristone et octréotide destinés à être utilisés selon la revendication 4, le radionucléide thérapeutique étant sélectionné dans le groupe constitué de 111In, 90Y, 177Lu et 213Bi.
HK18107713.1A 2015-03-02 2016-02-25 Mifepristone and octreotide for use in the treatment of cushing's syndrome in a patient having an adrenocorticotropic hormone (acth)-secreting pancreatic neuroendocrine tumor HK1248128B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562127153P 2015-03-02 2015-03-02
US62/127,153 2015-03-02
PCT/US2016/019646 WO2016140867A1 (fr) 2015-03-02 2016-02-25 Utilisation d'un antagoniste du récepteur des glucocorticoïdes et d'analogues de la somatostatine pour le traitement de tumeurs secrétant de l'hormone adrénocorticotrope (acth)

Publications (2)

Publication Number Publication Date
HK1248128A1 HK1248128A1 (en) 2018-10-12
HK1248128B true HK1248128B (en) 2024-04-19

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