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HK1129292A - A method of deriving central aortic systolic pressure and a method of analysing arterial waveform data to derive central aortic systolic pressure values - Google Patents

A method of deriving central aortic systolic pressure and a method of analysing arterial waveform data to derive central aortic systolic pressure values Download PDF

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Publication number
HK1129292A
HK1129292A HK09109025.1A HK09109025A HK1129292A HK 1129292 A HK1129292 A HK 1129292A HK 09109025 A HK09109025 A HK 09109025A HK 1129292 A HK1129292 A HK 1129292A
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Hong Kong
Prior art keywords
blood pressure
value
aortic systolic
arterial waveform
central aortic
Prior art date
Application number
HK09109025.1A
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Chinese (zh)
Inventor
陈崇铭
蔡岳辉
Original Assignee
健资国际私人有限公司
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Publication date
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Publication of HK1129292A publication Critical patent/HK1129292A/en

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Description

Method for obtaining central aortic systolic pressure and method for analyzing arterial waveform data to obtain central aortic systolic pressure value
Technical Field
The invention relates to a method for obtaining central aortic systolic pressure and a method for analyzing arterial waveform data to obtain a central aortic systolic pressure value. According to a first method of the invention, the invention is particularly applicable to deriving central aortic systolic pressure from an arterial waveform. However, according to the second method of the present invention, the present invention is adapted to analyze the set of arterial waveform data to obtain a corresponding set of central aortic systolic pressure data.
Background
The following discussion of the background to the invention is intended to facilitate an understanding of the present invention. However, it should be understood that this discussion is not an admission that any of the material referred to herein was published, known or part of the common general knowledge as at the time of priority of the invention, in accordance with any judicial interpretation.
In developed countries, heart disease is a serious health problem. Currently, one indication of heart disease is the deviation of the blood pressure of a human body from a predetermined normal range of values.
A common method of determining human blood pressure is to read the blood pressure (systolic and diastolic) of the human arm using a pressure cuff. These values are then typically used to replace central arterial blood pressure values. While this assumption has proven to be very beneficial in predicting potential heart disease, current research indicates that normal arm blood pressure values measured in this manner may mask abnormal central aortic systolic pressure values.
One solution to this problem has been found by Atcor Medical Pty Ltd of West Ryde, New Nanwester, Australia. The Atcor solution uses a unique conversion formula to convert the radial pressure waveform to the central arterial pressure waveform. However, this formula is only available through proprietary software available commercially from Atcor, as is SphygmocorTMBlood pressure monitoring systems are used together. More importantly, the formula is based on correlation values determined by measurements on the patient cross representation, and thus may result in patient central arterial pressure readings that fall outside the range of the cross representation sampling points.
Disclosure of Invention
Throughout this document, unless otherwise indicated, the words "comprise", "comprising", and the like are to be construed as non-exclusive or, in other words, mean "including but not limited to".
In the description of the embodiments of the present invention, the term "human body" refers to the body when arterial waveforms are generated. The present invention is not to be considered as limited to the exclusion of calculating central arterial pressure from the arterial waveform of a deceased patient.
According to a first aspect of the present invention, there is provided a method of deriving central aortic systolic pressure, including the steps of:
a) creating a set of a predetermined number of blood pressure measurements, the set representing an arterial waveform;
b) determining an integer interval value;
c) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
d) storing the average in a central aortic systolic pressure set; and
e) setting the central aortic systolic pressure to the highest value in the set of central arterial pressures, where the f-value starts at 1, repeating steps c and d, and incrementing the f-value by 1 each time until the f-value plus the integer interval value equals the predetermined number of blood pressure measurements in the set.
The set of blood pressure measurements should be substantially equivalent to a uniform distribution of the values of the arterial waveform. In particular, the method preferably comprises the step of determining the duration of said arterial waveform. The predetermined number is then determined using the waveform duration according to the following equation:
predetermined number sr × t
Wherein the content of the first and second substances,
sr ═ the sampling rate (hertz) of the measurement device used to record the blood pressure measurements in the set; and is
t is the duration of the arterial waveform.
The integer interval value is the result of a division of the sampling rate. Ideally, however, the integer interval value is the sampling rate divided by 4.
Alternatively, the integer interval value is the result of dividing a predetermined number of blood pressure measurements in the set of blood pressure measurements. Ideally, using this technique, the integer interval values are within a range whose boundaries are determined by the following equations:
iRange=n/(t×v)±(n/(t×30))
wherein
n is the predetermined number of blood pressure measurements in the set;
t is the duration of the waveform (in seconds); and
v is a predetermined division value.
Preferably, but not necessarily, the value of v is set to 4 when calculating the above range.
In another arrangement, the integer interval value is equal to 60 divided by a predetermined division value. In another setting, the integer interval value is 15.
The predetermined number of blood pressure measurements in the set is equal to or greater than 15. However, it is preferred that said predetermined number of blood pressure measurements in the set is at least 30.
In an optimized configuration, the predetermined number of blood pressure measurements in the set is at least 30 and the interval is 15.
According to a second aspect of the present invention, there is provided a method of analysing arterial waveform data to obtain central aortic systolic pressure values, comprising the steps of:
a) receiving an arterial waveform data set;
b) dividing each arterial waveform in the set of arterial waveform data into a representative set having a predetermined number of blood pressure measurements;
c) determining an integer interval value for the set of processes;
d) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
e) storing the average in a central aortic systolic pressure set; and
f) storing a highest value of the set of central arterial pressures at a location in a set of central aortic systolic pressure values corresponding to a location in the set of arterial waveform data occupied by the arterial waveform being processed,
wherein steps b to f are repeated for each arterial waveform in said set of arterial waveform data and for each such repetition, the value of f starts at 1 and is incremented by 1 each time, steps d and e are further repeated until the value of f plus said integer interval value equals said predetermined number of blood pressure measurements in said set processed.
According to a third aspect of the present invention, there is provided a method of analysing arterial waveform data to obtain central aortic systolic pressure values, comprising the steps of:
a) receiving a data set of arterial waveforms, wherein each arterial waveform in the data set comprises a representative set having a predetermined number of blood pressure measurements;
b) determining an integer interval value for the set of processes;
c) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
d) storing the average in a central aortic systolic pressure set; and
e) storing a highest value of the set of central arterial pressures at a location in a set of central aortic systolic pressure values corresponding to a location in the set of arterial waveform data occupied by the arterial waveform being processed,
wherein steps b to e are repeated for each arterial waveform in said set of arterial waveform data and for each such cycle f starts with 1 and is incremented by 1 each time, steps c and d are further repeated until f plus said integer interval value equals said predetermined number of blood pressure measurements in said set processed.
The predetermined number of blood pressure measurements for at least one arterial waveform in the data set is different from the predetermined number of blood pressure measurements for other arterial waveforms in the data set.
With regard to the second and third aspects of the invention, the set of blood pressure measurements should be substantially equal to a uniform distribution of the values of the arterial waveform.
Desirably, the method further comprises the step of determining the duration of said arterial waveform, wherein said predetermined number of blood pressure measurements is determined according to the following formula:
predetermined number sr × t
Wherein the content of the first and second substances,
sr ═ the sampling rate (hertz) of the measurement device used to record the blood pressure measurements in the set; and is
t is the duration of the arterial waveform.
The integer interval value may be the result of a division operation on said sampling rate (sr). Preferably, the integer interval value is the sampling rate divided by 4.
Alternatively, the integer interval value is the result of dividing a predetermined number of blood pressure measurements in the set of blood pressure measurements. Ideally, using this technique, the integer interval values are within a range whose boundaries are determined by the following equations:
iRange=n/(t×v)±(n/(t×30))
wherein
n is the predetermined number of blood pressure measurements in the set;
t is the duration of the waveform (in seconds); and
v is a predetermined division value.
In this formula, it is further preferable that the value of v be set to 4.
In another alternative configuration, the integer interval value is equal to 60 divided by the predetermined fraction value. In another configuration, the integer separation value is 15.
The predetermined number of blood pressure measurements in the set should be equal to or greater than 15. It is preferred to have a set of 30 blood pressure measurements.
According to a fourth aspect of the present invention, there is provided a system for deriving central aortic systolic pressure, including:
an arterial waveform measuring device; and
a processing unit for processing the received data,
wherein the arterial waveform measuring device performs blood pressure measurements at predetermined intervals until at least one arterial waveform is represented by a resulting set of blood pressure measurements, and then transmits the set of blood pressure measurements representing one arterial waveform to the processing unit, the processing unit:
a) determining an integer interval value;
b) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
c) storing the average in a central aortic systolic pressure set; and
d) setting the central aortic systolic pressure to the highest value in the set of central arterial pressures,
wherein f is started at 1, steps b and c are repeated, and f is incremented by 1 each time until f plus the integer interval value equals the number of blood pressure measurements in the set.
According to a further aspect of the invention there is provided a computer readable medium having stored thereon software for performing the method as described in the first, second and third aspects of the invention.
Drawings
The invention will now be described, by way of example, with reference to the accompanying drawings, in which:
fig. 1 is a flow chart of a method for determining the central arterial pressure of a human body according to a first embodiment of the present invention.
Fig. 2 is a flow chart of a method of analyzing an arterial waveform data set to derive a corresponding central arterial pressure data set according to a second embodiment of the present invention.
Fig. 3 is an exemplary arterial waveform that may be processed by any particular embodiment of the present invention to obtain a central arterial pressure value.
Detailed Description
Specific embodiments of the present invention will now be described with reference to the accompanying drawings. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the scope of the present invention. In addition, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
According to a first embodiment of the present invention, a method of determining central arterial pressure 10 is disclosed. The method 10 is shown in flow chart form in fig. 1.
As shown in FIG. 1, the method 10 begins with the creation of a blood pressure measurement combination from a human representative of an arterial waveform (step 12). The set of blood pressure measurements has a predetermined number of measurements (n). At step 14, the predetermined number n is divided by the preset value (v) to determine an integer interval value (i). Thus, the integer interval value (i) may be obtained by an absolute value or a rounding function.
The following steps are then repeated starting from the first blood pressure measurement bp [ (f) ]:
adding the blood pressure measurement results { bp [ f ], bp [ f +1], bp [ f +2], bp [ f +3], bp [ f + i-1] } (step 16) to obtain a value s;
dividing the sum s by the interval value i to obtain a mean blood pressure value (a) (step 18);
the mean blood pressure value a is stored in the central arterial pressure set (step 20).
The above steps (steps 16 to 20) are repeated until f + i-1 equals n.
Step 22 analyzes the set of central arterial pressure values to determine the highest value (h) in the set. The highest value h is then used as a value that generally represents the systolic central arterial pressure of the body.
According to a second embodiment of the invention, there is a method of analyzing an arterial waveform data set to obtain a corresponding central arterial pressure data set 100. The generally prior method of this particular embodiment is for the medical professional to obtain an arterial waveform representative of the human blood pressure according to any technique known to those skilled in the art. The arterial waveform representation is then provided to a central processing station for determining a corresponding central arterial pressure. After receiving the representation of the arterial waveform, the central processing station operates as follows:
for each arterial waveform in the waveform data set, a corresponding central arterial pressure value a is determined and stored in the central arterial pressure data set according to the following procedure.
The processed arterial waveforms 102 are divided into a set of representative blood pressure measurements (step 10). The set of blood pressure measurements has a predetermined number of measurements (n). At step 112, the predetermined number n is divided by the preset value (v) to determine an integer interval value (i).
The following steps are then repeated starting from the first blood pressure measurement bp [ (f) ]:
adding the blood pressure measurement results { bp [ f ], bp [ f +1], bp [ f +2], bp [ f +3], bp [ f + i-1] } (step 114) to obtain a value s;
the summed value s is divided by the interval value i to obtain a set of mean blood pressures (a) (step 116).
The mean blood pressure value a is stored in the central arterial pressure set (step 118).
The above steps (steps 114 to 118) are repeated until f + i-1 equals n.
Step 120 analyzes the set of central arterial pressure values to determine the highest value (h) in the set. The highest value h is then stored in the central arterial pressure data set as the central aortic systolic pressure value corresponding to the processed arterial waveform.
The above steps are then repeated until the corresponding central arterial pressure value for each arterial waveform in the waveform data set has been calculated.
According to a third embodiment of the present invention, in which like numerals indicate like steps, there is a method (not shown) of analyzing the arterial waveform data set to obtain a corresponding central arterial pressure data set. This particular embodiment is based on experiments conducted by the applicant, wherein it has been found that the value of n can be any value exceeding 15.
In this particular embodiment, although a preferred value of v is 4 to determine the appropriate interval, a substantially accurate value of arterial pressure can be obtained within a range of interval values, the limits of which are determined by:
iRange=n/(t×v)±(n/(t×30))
wherein the variable t represents the duration of one waveform (in seconds) in this particular embodiment.
This embodiment will now be described in more detail with the following example as background:
according to step 12, a set of blood pressure measurements from the human body representing the arterial waveform is obtained. The measurements are as follows (sequential, left to right, top to bottom):
62.0 63.6 73.1 91.1 112.3 132.1 149.6 165.4 176.0 180.7
182.0 181.9 181.3 180.2 178.8 176.8 174.4 171.5 167.9 163.1
156.4 147.8 137.1 125.1 114.0 106.2 102.3 101.1 100.7 99.8
98.2 95.9 93.2 90.6 88.1 85.8 83.9 82.2 80.4 78.7
77.2 76.2 75.5 74.7 73.7 72.7 72.0 71.5 71.1 70.5
69.9 69.1 68.4 67.5 66.9 66.1 65.5 65.1 64.9 64.8
64.4 63.8 63.3 62.9 62.7 62.8 63.1 63.3 63.5 63.6
63.6 63.5 63.4 63.0 62.5 62.0
the duration used to complete the waveform is 1.27 seconds.
This sets n to 76. If v is 4, interval value range (i)range) Is determined by the following formula:
iRangen/(t × v) ± (n/(t × 30)), and thus
iRange76/(1.27 × 4) ± (76/(1.27 × 30)), and thus
iRange=14.96±(1.99)
Since the interval cannot be an integer valueOther values than irangeThe value is limited to 13 to 17
Within the range of (1). For this example, the value of i used is 15.
The central arterial pressure set values are generated as follows, as required in steps 16 to 20:
{140.7 148.3 155.7 162.3 167.4 170.8
172.4 172.3 170.4 167.0 162.5 157.5
152.2 146.8 141.5 136.3 131.0 125.8
120.6 115.4 110.4 105.7 101.5 97.8
94.8 92.5 90.5 88.8 87.1 85.4
83.6 81.9 80.3 78.9 77.6 76.4
75.3 74.4 73.4 72.6 71.8 71.1
70.3 69.6 69.0 68.4 67.8 67.3
66.7 66.2 65.7 65.2 64.8 64.5
64.2 64.0 63.8 63.7 63.6 64.5
63.3 63.1}
as can be seen, the central arterial pressure set has 62 elements whose values are equal to n-i + 1. It is clear from the set that the highest value (h) in the set is actually the 7 th data element (172.4). Thus, the central aortic systolic pressure of the human body was determined to be 172.4.
In a fourth and most preferred embodiment of the invention, there is a method of determining central arterial pressure as described in the first embodiment of the invention. However, in this particular embodiment, the predetermined number n is determined according to the following formula:
n=sr×t
wherein
sr-the sampling frequency (hertz) of the measuring device used to record the blood pressure measurements in the set bp; and
t is the time (seconds) taken to complete an arterial waveform.
In this particular embodiment, the blood pressure measurements in the set bp are measurements obtained by the measurement device at each repetition of the sampling rate. Additionally, in this particular embodiment of the invention, the spacing value is within a range, the limits of which are determined as follows:
iRange=sr/v±(sr/30)
thus sr also represents the sampling frequency (hertz) of the measuring device, which is used to record the blood pressure measurements in the set bp. Further, the value of v is preferably 4. And this formula can only be applied if the sr value exceeds 30.
The same set of blood pressure measurements as set forth above is used, but this time i is calculated in the case where the set is the peak of blood pressure values obtained by a sampling device having a sampling frequency (sr) of 60 measurements per secondRangeThe values are as follows:
iRange=sr/v±(sr/30)
iRange=60/4±(60/30)
iRange=15±2
this will result in iRangeThe value is between 13 and 17. The remainder of the method may then proceed as set forth above for the first embodiment.
It will be appreciated by persons skilled in the art that the above invention is not limited to the specific embodiments described above. In particular, the following changes and modifications may be made without departing from the scope of the invention:
the set of blood pressure measurements may be obtained from a device that is also used to perform the method of the invention. Alternatively, the blood pressure measurement may be obtained from a separate device and transmitted to a further device for performing the method of the invention.
The second specific embodiment of the invention may be modified so that the waveform data set does not contain waveforms-alternatively, the waveform data set data may contain data sets representative of these waveforms. Thus, the process of step 110 may be omitted.
The waveform data set may be provided to an entity that performs the method for the duration of each waveform in the data set. Alternatively, the entity performing the method may independently determine the duration of each waveform by another method (e.g., by receiving a graph of a predetermined length of the x-axis with a fixed time value and estimating the waveform duration given the time/distance relationship, or obtaining the duration from other complex values, such as the sampling rate used to generate the set of blood pressure measurements).
As the most representative result of the arterial waveform, the blood pressure values constituting the set bp should follow the uniform distribution of the arterial pulse shape.
It will also be appreciated by persons skilled in the art that the features described above are not mutually exclusive and may be combined to form other embodiments of the invention.

Claims (30)

1. A method of deriving central aortic systolic pressure comprising the steps of:
a. creating a set of a predetermined number of blood pressure measurements, the set representing an arterial waveform;
b. determining an integer interval value;
c. averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
d. storing the average in a central aortic systolic pressure set; and
e. setting the central aortic systolic pressure to the highest value in the set of central arterial pressures,
wherein f is started at 1, steps c and d are repeated, and f is incremented by 1 each time until f plus the integer interval value equals the predetermined number of blood pressure measurements in the set.
2. A method of deriving central aortic systolic pressure according to claim 1, where the set of blood pressure measurements is substantially equivalent to a uniform distribution of the arterial waveform values.
3. The method of deriving central aortic systolic pressure according to claim 2, further including the step of determining the duration of the arterial waveform, where the predetermined number of blood pressure measurements is determined according to the following equation:
predetermined number sr × t
Wherein the content of the first and second substances,
sr ═ the sampling rate (hertz) of the measurement device used to record the blood pressure measurements in the set; and is
t is the duration of the arterial waveform.
4. A method of deriving central aortic systolic pressure according to claim 3, where the integer interval value is the result of a division of the sampling rate.
5. A method of deriving central aortic systolic pressure according to claim 4, where the integer interval value is the sampling rate divided by 4.
6. A method of deriving central aortic systolic pressure according to claim 1 or 2, where the integer interval value is the result of a division of the predetermined number.
7. A method of deriving central aortic systolic pressure according to claim 6, where the integer interval value is within a range bounded by the following equation:
iRange=n/(t×v)±(n/(t×30))
wherein n is the predetermined number of blood pressure measurements in the set;
t is the duration of the waveform (in seconds); and
v is a predetermined division value.
8. The method of deriving central aortic systolic pressure according to claim 7, where v-4.
9. A method of deriving central aortic systolic pressure according to claim 1 or claim 2, where the integer interval value is equal to 60 divided by a predetermined segmentation value.
10. A method of deriving central aortic systolic pressure according to claim 9, where the integer interval value is 15.
11. Method of deriving central aortic systolic pressure according to any one of the preceding claims, where the predetermined number of blood pressure measurements in the set is equal to or greater than 15.
12. A method of deriving central aortic systolic pressure according to claim 11, where the predetermined number of blood pressure measurements in the set is at least 30.
13. A method of analyzing arterial waveform data to obtain central aortic systolic pressure values, comprising the steps of:
a) receiving an arterial waveform data set;
b) dividing each arterial waveform in the set of arterial waveform data into a representative set having a predetermined number of blood pressure measurements;
c) determining an integer interval value for the set of processes;
d) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
e) storing the average in a central aortic systolic pressure set; and
f) storing a highest value of the set of central arterial pressures at a location in a set of central aortic systolic pressure values corresponding to a location in the set of arterial waveform data occupied by the arterial waveform being processed,
wherein steps b to f are repeated for each arterial waveform in said set of arterial waveform data and for each such repetition, the value of f starts at 1 and is incremented by 1 each time, steps d and e are further repeated until the value of f plus said integer interval value equals said predetermined number of blood pressure measurements in said set processed.
14. A method of analyzing arterial waveform data to obtain central aortic systolic pressure values, comprising the steps of:
a) receiving a data set of arterial waveforms, wherein each arterial waveform in the data set comprises a representative set having a predetermined number of blood pressure measurements;
b) determining an integer interval value for the set of processes;
c) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
d) storing the average in a central aortic systolic pressure set; and
e) storing a highest value of the set of central arterial pressures at a location in a set of central aortic systolic pressure values corresponding to a location in the set of arterial waveform data occupied by the arterial waveform being processed,
wherein steps b to e are repeated for each arterial waveform in said set of arterial waveform data and for each such repetition, the f-value starts at 1 and is incremented by 1 each time, steps c and d are further repeated until the f-value plus said integer interval value equals said predetermined number of blood pressure measurements in said set processed.
15. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to claim 14, where the predetermined number of blood pressure measurements for at least one arterial waveform in the data set is different from the predetermined number of blood pressure measurements for other arterial waveforms in the data set.
16. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to any one of claims 13 to 15, where the set of blood pressure measurements is substantially equal to a uniform distribution of the arterial waveform values.
17. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to claim 16, further including the step of determining the duration of the arterial waveform, where the predetermined number of blood pressure measurements is determined according to the following equation:
predetermined number sr × t
Wherein the content of the first and second substances,
sr ═ the sampling rate (hertz) of the measurement device used to record the blood pressure measurements in the set; and is
t is the duration of the arterial waveform.
18. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to any one of claims 13 to 17, where the integer interval value is the result of a division of the sampling rate.
19. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to claim 18, where the integer interval value is the sampling rate divided by 4.
20. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to any one of claims 13 or 17, where the integer interval value is the result of a division of the predetermined number.
21. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to claim 20, where the integer interval value is within a range, the boundaries of which are determined by the following equation:
iRange=n/(t×v)±(n/(t×30))
wherein n is the predetermined number of blood pressure measurements in the set;
t is the duration of the waveform (in seconds); and
v is a predetermined division value.
22. A method of deriving central aortic systolic pressure according to claim 21, where v-4.
23. A method of deriving central aortic systolic pressure according to claim 13 or 14, where the integer interval value is equal to 60 divided by a predetermined segmentation value.
24. A method of deriving central aortic systolic pressure according to claim 23, where the integer interval value is 15.
25. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to any one of claims 13 to 24, where the predetermined number of blood pressure measurements in the set is equal to or greater than 15.
26. A method of analysing arterial waveform data to derive central aortic systolic pressure values according to claim 25, where the predetermined number of blood pressure measurements in the set is at least 30.
27. A system for deriving central aortic systolic pressure, comprising:
an arterial waveform measuring device; and
a processing unit for processing the received data,
wherein the arterial waveform measuring device performs blood pressure measurements at predetermined intervals until at least one arterial waveform is represented by a resulting set of blood pressure measurements, and then transmits the set of blood pressure measurements representing one arterial waveform to the processing unit, the processing unit:
a) determining an integer interval value;
b) averaging a series of consecutive blood pressure measurement readings in the set equal to the integer interval value, starting from the f-th blood pressure measurement in the set;
c) storing the average in a central aortic systolic pressure set; and
d) setting the central aortic systolic pressure to the highest value in the set of central arterial pressures,
wherein f is started at 1, steps b and c are repeated, and f is incremented by 1 each time until f plus the integer interval value equals the number of blood pressure measurements in the set.
28. A computer readable medium having software recorded thereon for deriving central aortic systolic pressure, the software comprising:
aggregation means for creating an aggregate having a predetermined number of blood pressure measurements, the aggregate representing an arterial waveform;
means for determining an integer interval value;
averaging means for averaging a series of successive blood pressure measurement readings in said set equal to said integer interval value, starting from the fth blood pressure measurement in said set;
a storage means for storing the average value in a central aortic systolic pressure set; and
a result means for setting the central aortic systolic pressure to the highest value in the set of central arterial pressures,
wherein the f-value starts at 1, the functions of the averaging means and the storage means are repeated and the f-value is incremented by 1 each time until the f-value plus the integer interval value equals the predetermined number of blood pressure measurements in the set.
29. A computer readable medium having software recorded thereon for analyzing arterial waveform data to obtain central aortic systolic pressure values, the software comprising:
a transmission device for receiving the set of arterial waveform data,
aggregating means for dividing each arterial waveform in said set of arterial waveform data into a representative set having a predetermined number of blood pressure measurements;
interval means for determining an integer interval value for said set of processes;
averaging means for averaging a series of successive blood pressure measurement readings in said set equal to said integer interval value, starting from the fth blood pressure measurement in said set;
a first storage means for storing the average value in a central aortic systolic pressure set; and
second storage means for storing the highest value of said set of central arterial pressures at a location in the set of central aortic systolic pressure values corresponding to the location in said set of arterial waveform data occupied by said processed arterial waveform,
wherein the functions of the aggregating means, the spacing means, the averaging means, the first storage means and the second storage means are repeated for each arterial waveform in the set of arterial waveform data, and for each such repetition, the f-value starts at 1 and is incremented by 1 each time, the functions of the averaging means and the first storage means being further repeated until the f-value plus the integer spacing value equals a predetermined number of blood pressure measurements in the processed set.
30. A computer readable medium having software recorded thereon for analyzing arterial waveform data to obtain central aortic systolic pressure values, the software comprising:
a) transmitting means for receiving a data set of arterial waveforms, wherein each arterial waveform in the data set comprises a representative set having a predetermined number of blood pressure measurements;
b) interval means for determining an integer interval value for said set of processes;
c) averaging means for averaging a series of successive blood pressure measurement readings in said set equal to said integer interval value, starting from the fth blood pressure measurement in said set;
d) a first storage means for storing the average value in a central aortic systolic pressure set; and
e) second storage means for storing the highest value of said set of central arterial pressures at a location in the set of central aortic systolic pressure values corresponding to the location in said set of arterial waveform data occupied by said processed arterial waveform,
wherein the functions of the spacing means, averaging means, first storage means and second storage means are repeated for each arterial waveform in the set of arterial waveform data and for each such repetition the value of f starts at 1 and is incremented by 1 each time, the functions of the averaging means and first storage means being further repeated until the value of f plus the integer spacing value equals the predetermined number of blood pressure measurements in the set processed.
HK09109025.1A 2007-06-07 A method of deriving central aortic systolic pressure and a method of analysing arterial waveform data to derive central aortic systolic pressure values HK1129292A (en)

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