HK1180928B - Lancing device having automatic triggering - Google Patents

Description

Automatically triggered puncture aid

The invention relates to a lancing aid for removing body fluids for diagnostic purposes, having a coupled clamping and triggering mechanism, wherein the triggering mechanism is mechanically coupled to the clamping mechanism such that a lancing process is automatically triggered by a continuous, continuous clamping movement when the clamping mechanism is actuated, wherein the lancing process thus triggered is carried out by a lancet.

For various diseases, it is necessary to examine analytes contained in body fluids, particularly human blood. In many cases, creating a small puncture wound is sufficient to remove a small amount of the desired bodily fluid from the body, particularly blood in the form of a blood drop. One particularly important case of this is diabetes, where the glucose content must be checked regularly. Other blood tests may be performed, for example, for coagulation parameters, triglycerides, HbA1c or lactate. In order to produce the required puncture wound, a blood lancet device is usually used, which is composed of a puncture device and a replaceable lancet adapted to the puncture device. In the housing of the lancing device there is a lancet holder in which each lancet can be inserted in a replaceable manner. During the pricking process, the lancet holder is moved rapidly in the pricking direction by means of a lancet actuator which is also integrated in the pricking device, until the lancet tip protrudes through an extension opening defined by the front end of the pricking device and a small puncture wound is produced in the body part against which the front end is pressed. The lancet holder together with the lancet is then moved back counter to the pricking direction.

Over time, small portable sampling devices, so-called piercing aids, have been built which can be operated easily and reliably by the user and which make possible as painless a penetration into a body part as possible. To avoid infection, particularly in wards, lancets are disposable (disposable) components that are intended for single use. After the single use lancet, the lancet is removed after the lancing process or is discarded from the device and disposed of.

In addition to the use of blood lancet devices by medical personnel, lancing aids are also used by laymen in the so-called home monitoring field. This is particularly suitable for therapeutic examinations of diabetic patients. Thus in treating a diabetic, it is determined that serious injuries associated with diabetes, such as blindness, can be critically reduced if the glucose concentration in the blood of the diabetic is determined frequently up to five times a day and the insulin injection amount can be accurately adjusted based on such measurements. In order to carry out such frequent measurements, puncture aids are used in the field of home monitoring, so that the diabetic can carry out a blood test himself. Thus, there is a demand for a blood lancet device that can be easily operated when a new lancet is used, and that can be safely discarded, in addition to the need for easy operation when the pricking process is triggered and the pricking is not painful. On the one hand, the lancet is to be changed as easily as possible, but on the other hand, the greatest degree of safety is to be ensured against undesired injuries of the user and also of third parties. In the field of home care, it is conceivable here for the user to use the disposable lancet for pricking several times; here, however, the discarded lancet is also prevented from being inadvertently reused after the user has decided to discard the lancet. In addition, protection of the discarded lancet is ensured, in particular for third parties, for example when removing waste.

For the foregoing reasons, there is therefore an increasing need for devices which enable a user to monitor his blood glucose level or also the concentration of other analytes in other body fluids in the field of home monitoring in as comfortable, uncomplicated and in particular as pain-free a manner as possible by measuring as frequently as possible.

EP0668049a1 discloses a self-clamping lancet mechanism comprising a trigger button which is acted upon by a trigger button spring and a drive spring, which connects the trigger button to a plunger. Upon triggering, the trigger button spring is compressed and, once the user releases the trigger button, the trigger button spring will bring the plunger and the trigger button back into the clamped position under the prestress of the trigger button spring. The disclosed lancet mechanism is automatically clamped, and thus independently clamped and unclamped. The lancet mechanism is thus gripped and triggered by two separate actuations of the trigger button.

US2008/0195132a1 discloses special lancing aids, each having a clamping and drive spring, wherein the drive spring is connected to a holding part for receiving a lancet. In one embodiment, the lancing aid has an automatic clamping and triggering system, wherein the lancing aid is first clamped by actuation of a clamping button and then automatically triggered by release of a trigger button, i.e., by relaxation of a clamping spring. By the extension of the clamped drive spring, the holding part and the lancet connected thereto are driven in the pricking direction, and are pulled back into the housing by the relaxation of said drive spring.

The subject matter of WO03/073936a2 is a single-use device for puncturing the skin of a patient, which has a pressing member with which both the drive spring can be clamped and the puncturing movement can be carried out by the puncturing unit as a function of the mechanical overstress of the internal holding member. For this purpose, the device is placed on the skin portion to be punctured and pressed by means of the pressure element. After the puncturing movement has been carried out, the released puncturing unit is pulled back into position within the device by means of a restoring spring.

WO02/05872A2 discloses a one-way lancing aid that can be gripped and fired by a single actuation of the trigger in only one direction. Here, the lancet is driven from the sterile environment into the pricking direction by means of a clamped spring within the device and is pulled back into the housing after the pricking. The device can neither be adapted individually to the penetration depth nor to the drive force or speed.

An automatic lancing aid is described in US6,986,777, which also has a single trigger button for both clamping and triggering. The puncture aid also has a mechanism that causes the guide pin to move in a guide, wherein the guide has a circumferential portion and a longitudinally extending section. When the trigger button is actuated, the lancing aid is clamped and the guide pin is moved in the guide, wherein the lancing movement is automatically triggered when the longitudinally extending section of the guide is reached. Here, the plunger, which is not initially engaged with the lancet, is accelerated towards the lancet, the plunger striking the lancet, thereby carrying out the pricking movement.

EP1384438a1 discloses a blood sampling system for taking a blood sample for diagnostic purposes, comprising a housing, a lancet guide and a lancet driver with a drive spring. The lancet drive comprises a clamping mechanism for clamping the drive spring, a drive rotor driven by the drive spring, and a coupling mechanism on the output side, by means of which the rotational movement of the drive rotor is converted into a puncturing movement. It is also specified that the lancet drive can be provided with a self-triggering catch.

Against this background, the object of the invention is to provide a puncture aid which makes it possible to provide

As little effort as possible to flower;

in as simple and intuitive a manner as possible, in particular with as few operating steps as possible;

in the case of a minimally invasive incision,

the handling is carried out in that it is easy to handle, in particular the external dimensions are as small as possible, and the number of additional components is as small as possible, and therefore economical to produce. Furthermore, the puncture aid assists the user in lowering the braking threshold for producing the puncture wound.

According to the present invention, a system for removing a body fluid for diagnostic purposes is proposed, whereby said purpose is achieved, the system comprising:

-a sampling device and at least one lancet matched to the sampling device, the lancet having a lancet body and a lancet tip;

-a housing with an extension opening for the lancet tip;

-a lancet holder movable within the housing along a predetermined puncture path for replaceably holding a lancet;

a lancet guide for guiding the lancet holder over a predetermined pricking path after triggering the pricking movement;

a lancet drive with an elastic drive part, which can be transferred by clamping from an undamped state to a clamped state, with which the relaxation movement of the clamped elastic drive part is converted into a pricking movement after triggering, wherein the lancet held by the lancet holder is moved along a predetermined pricking path in the pricking direction until the lancet tip at least partially protrudes from the protrusion opening, with which the lancet holder returns to the position of the lancet tip in the housing; and

a combined clamping and triggering mechanism with an activation part accessible from outside the housing, the activation part having an initial state and an activation state, wherein the combined clamping and triggering mechanism has a locking device which is mechanically coupled with the activation part and the lancet drive such that the lancet drive is initially clamped when the activation part is moved along an activation path and then triggered, wherein triggering of the lancet drive is allowed when a certain point is reached along the activation path.

The system of the invention is suitable for removing body fluids such as blood or interstitial fluid, preferably blood for diagnostic purposes. Since for diagnostic purposes usually only a small amount of the body fluid to be examined, preferably blood, is required, the system according to the invention is used to remove small amounts of the corresponding body fluid, preferably blood, wherein the amount to be removed is usually from about 0.5 to about 5. mu.l, often from about 1 to about 3. mu.l.

In order to remove said small amount of selected body fluid, preferably blood, it is usually performed on a previously selected skin portion, for example on a fingertip or on an earlobe, using the system of the invention. The lancet comprised in the system according to the invention is usually inserted as quickly as possible into the selected skin portion, whereby the desired incision is made. In this way, a desired small amount of the corresponding body fluid can be discharged from the selected skin portion.

The system of the invention is preferably a reusable system for sampling body fluids, preferably blood, i.e. such a system is not intended for single use. Accordingly, the system of the present invention, and in particular the sampling device comprised by the system, can be used once or several times in succession, preferably continuing after replacing each used lancet with an unused lancet.

The system of the present invention includes a sampling device and at least one lancet mated to the sampling device, the lancet having a lancet body and a lancet tip. As previously mentioned, the sampling device is suitable for both single use and multiple use, but multiple use is preferred. According to a preferred embodiment, the system of the present invention can be used multiple times, optionally with repeated use of used lancets, or preferably after replacement of a used lancet with an unused lancet. Here, a used lancet is a lancet with which one or more pricks have been made.

The system of the present invention includes a lancet having a lancet tip and a lancet body, which may be designed as a whole or in multiple parts. In the case of a multiple design, the lancet body and the lancet tip can be made of the same material or, preferably, of different materials. As suitable materials for the lancet tip, metals such as stainless steel or special spring steel need to be mentioned. The lancets used in the system of the present invention preferably comprise lancet tips made of stainless steel which are connected to a lancet body, particularly preferably made of acrylonitrile butadiene styrene, which is preferably made of a suitable material.

The lancet used in the system according to the invention preferably also has a protective body which surrounds the lancet tip for producing the skin incision, so that contamination of the lancet tip by dirt or bacteria can be avoided and the sterility of the unused lancet can be ensured. Such shields, also referred to as antibacterials, are well known to those skilled in the art and are described, for example, in EP1263320a 1. Such a protective body is usually made of a suitable plastic and can be removed either before use of the lancet or during use, i.e. during penetration of the lancet tip.

The system of the present invention, and more particularly the system includes a sampling device having a housing with an extended opening for the lancet tip. The housing preferably has an elongated shape, which preferably has a main axis (a). Here, the extension opening for the lancet tip is located at one end of the elongate housing. This end is referred to herein as the proximal end of the housing.

The system of the present invention further includes a lancet holder movable in the housing along a predetermined, generally linear, lancing path for replaceably holding the lancet. The predetermined piercing path is preferably oriented parallel to the main axis (a) of the housing. The lancet holder provided according to the invention serves to receive the lancet and is advantageously designed such that it holds the lancet during a movement along the pricking path for the purpose of carrying out the aforementioned skin incision, i.e. is permanently but releasably mechanically coupled to the lancet. Accordingly, in accordance with the understanding of the present invention, the term "replaceably held" means that the lancet holder is coupled to the lancet at least during the pricking process, so that the mechanical coupling between the lancets, preferably between the lancet body and the lancet holder, remains uninterrupted and is released or remains unchanged after the pricking process has ended. In this way, it is possible to selectively continue using the used lancet after the pricking process has been carried out, or to throw the lancet away and replace it with another, preferably unused, lancet.

The mechanical coupling between the lancet and the lancet holder can be achieved, for example, by press fitting or by gluing or snapping. Suitable lancet holders for the system according to the invention are described, for example, in EP0565970a 1. In this way, the lancet body can be surrounded by a form-fitting manner, for example by a lancet holder. The positive-locking coupling between the lancet body and the lancet holder can also be achieved in the following cases: the lancet holder is designed as a plunger which has a holding device with which a releasable form-fitting coupling with the holding region of the lancet is produced, as described, for example, in WO02/36010a1, see this document. In particular when using a plurality of lancets in the form of a lancet magazine in the system according to the invention, a form-fitting coupling between the lancet holder designed as a plunger and the lancet with holding section has proven to be advantageous in accordance with the latter solution.

The sampling device of the system of the present invention further comprises a lancet guide for guiding the lancet holder in a predetermined, generally straight, lancing path after triggering the lancing movement. The puncture path preferably runs along a straight line parallel to the main axis (a) of the housing. The lancet guide can advantageously be realized such that the lancet holder and thus the lancet held in the lancet holder or connected thereto can be mechanically coupled to the lancet drive at least during the entire pricking process. The term "pricking process" is used here in the sense of the present invention to mean the entire movement cycle of the lancet, whereby the lancet is initially moved from a rest position in the housing towards the extension opening on the proximal end of the housing, where at least a part of the lancet tip extends from the housing, and at the point of maximum movement the direction of movement is reversed, the lancet being moved back in the opposite direction until the lancet tip is again in a position inside the housing, preferably until the lancet tip has again reached its original rest position. The lancet can advantageously be permanently in contact with other guide elements, such as one or more guide rails. The guide elements or guide rails can be arranged, for example, on the inner side of the housing of the system according to the invention. They can preferably also be part of the lancet magazine as detailed above. They can be arranged, for example, on the inner surface of the magazine housing. Alternatively, the magazine housing itself can also be designed so that it serves as a guide element. In this way, for example, the lancets of the individual magazine can be arranged in individual compartments, preferably in individual cartridges, wherein the respective cartridge wall can serve as a guide. In this way, the movement of the lancet can be additionally stabilized during the pricking movement, and a permanent contact can also be achieved between the lancet drive and the lancet connected to the lancet holder, which is desirable in particular for painlessly performing skin incisions.

The system according to the invention further comprises a lancet drive with an elastic drive part, which can be transferred by clamping from an undamped state to a clamped state, with which the relaxation movement of the clamped elastic drive part is converted into a pricking movement after triggering, wherein the lancet held by the lancet holder is moved along a predetermined pricking path in the pricking direction until the lancet tip at least partially protrudes from the protrusion opening, whereby the lancet holder preferably returns to the position of the lancet tip in the housing.

As resilient drive part suitable within the scope of the invention, mention may in particular be made of springs, which can be made of all resilient materials which are suitable as seen by the person skilled in the art, in particular plastics, preferably metals, such as spring steel 1.4310, and which can be used in various different designs, for example as coil springs or leaf springs, preferably as coil springs. The elastic drive element can be clamped in various ways, for example by extending the helical spring along its axis of rotation or preferably by rotating the helical spring about its axis of rotation. Alternatively, the clamping can also be carried out by deflecting the leaf spring out of the rest position.

From the clamped state of the elastic drive part to be realized in this way, the release movement of the clamped elastic drive part is converted into a pricking movement of the lancet holder and thus of the lancet held in the lancet holder by the triggering thereof. During this pricking movement, the lancet held by the lancet holder is moved, as described above, along a predetermined pricking path in the pricking direction until the lancet tip at least partially protrudes from the protrusion opening, whereby the lancet holder preferably returns to the position of the lancet tip in the housing, preferably until the lancet holder or the lancet is again in the initial rest position. It has proven advantageous here if the lancet holder and thus also the lancet connected thereto are mechanically permanently coupled to the lancet drive, preferably during the entire pricking and return movement of the lancet, and the lancet drive thus continuously drives both the lancet holder or the lancet with a pricking movement and the lancet with a return movement. Such positively guided drives are known to the person skilled in the art, for example in the form of crank drives, lever drives, slide gates or cam drives.

As an actuating element that can be used within the scope of the invention, it has been found to be particularly suitable to use an actuating element having a transmission element, by means of which a torque introduced at the input end of the transmission element is converted into a longitudinal movement in the direction of the predetermined pricking path, wherein the longitudinal movement of the output end of the transmission element is transmitted to the lancet holder. Such drives are known, for example, from EP0565970a1 and EP1384438a1, see said documents. As in the above-mentioned documents, the term "transmission" is used within the scope of the invention to mean a movement device for coupling and translating the movement, in which case the movement when the elastic drive part, preferably the elastic drive spring, is relaxed is translated into a movement of the lancet holder or of the lancet replaceably held in the lancet holder.

In a preferred embodiment of the system according to the invention, the lancet drive has a rotary drive with a rotatable drive rotor, by means of which a torque introduced at the input of the rotary drive is converted into a longitudinal movement in the direction of the predetermined insertion path, wherein the drive rotor of the rotary drive is coupled to the elastic drive element and the longitudinal movement of the output of the rotary drive is transmitted to the lancet holder. Here, the drive rotor can be made to rotate both about an axis of rotation parallel to the predetermined puncturing path and about an axis of rotation perpendicular to the predetermined puncturing path. Within the scope of the invention, the drive rotor is preferably rotated about an axis of rotation parallel to the predetermined puncturing path, i.e. preferably about an axis of rotation parallel to the main axis (a) of the housing.

The rotational movement of the drive rotor is preferably converted by means of a curved control element into a translational movement parallel to its axis of rotation, wherein at least a part of the penetration movement, preferably also the return movement, particularly preferably the entire penetration and return movement, is determined by the relative movement of a control bolt in a recess forming a control curve, wherein the bolt passes through the control curve formed by the recess. Preferably, the carousel drive has a recess which can be rotated together with the drive rotor, into which recess a matching control bolt is inserted, wherein at least a part of the insertion and return movement is determined by the relative movement between the control bolt and the recess, wherein the control bolt passes through a control curve formed by the recess. In a particularly preferred embodiment of the system according to the invention, the recess which forms the control curve and is rotatable together with the drive rotor is designed such that, during the actuation of the operating element, the bolt passes completely or at least partially but preferably completely through said recess in a continuous, i.e. uninterrupted, movement. In a further preferred embodiment, the drive rotor is configured as a cylindrical sleeve, inside which a piston-shaped part is arranged, which slides with a cylindrical outer wall in the sleeve when being moved longitudinally towards the puncturing path.

According to one advantageous embodiment, the system according to the invention has a lancet drive with two rotors, the first rotor being referred to as the gripping rotor and the second rotor being referred to as the drive rotor. The rotors are also preferably coupled to each other by a drive spring as described above, and furthermore preferably have the same axis of rotation parallel to the main axis (a) of the system of the invention. According to this design, the clamping and driving rotors have the same direction of rotation and are each rotated 360 ° in succession. For this reason, this drive is also referred to as "360 ° drive". The drive is described in detail in EP1034740a1, for example.

The system of the invention further comprises a combined clamping and triggering mechanism with an activation part that can be moved from outside the housing, the activation part having an initial state and an activation state, wherein the combined clamping and triggering mechanism has a locking means that is mechanically coupled to the activation part and the lancet drive such that the lancet drive is initially clamped and then triggered when the activation part is moved along an activation path, preferably in the proximal direction of the system of the invention, wherein a certain point along the activation path is reached allowing the lancet drive to be triggered.

According to the invention, the combined clamping and triggering device is used both for clamping and for triggering the lancet drive as described above. The clamping and triggering device comprises an activation element which is accessible from outside the housing and which can be moved by activation from an initial state into an activated state. Here, according to a preferred embodiment, the activating member is suitably arranged such that it is at least partially inserted into the housing by being moved. It is furthermore preferred that the actuation member is at least partly inserted by movement into an end of the housing facing away from the penetration opening, which is referred to as "distal end" of the housing in the following. The activating member is here also preferably arranged such that said movement takes place along a preferably straight activating path. It is also preferred that the preferably straight activation path runs parallel to the pricking path of the lancet, i.e. preferably parallel to the main axis (a) of the housing. In a preferred embodiment of the invention, the activating member is an operating button that protrudes from the end, i.e., the distal end, of the rear face of the housing facing away from the lancet tip extension opening.

The activation member, preferably an operating button as described above, has an initial state and an activated state according to the invention and can be moved from the initial state into the activated state. In a particularly preferred embodiment of the invention, the operating button can be inserted or pressed into the housing towards the proximal end thereof.

According to the invention, the combined clamping and triggering device is preferably coupled to the lancet drive in such a way that the elastic drive part of the lancet drive initially passes from the undamped state to the clamped state by a continuous movement of the actuating part in one direction and then is preferably automatically triggered. The term "continuously" is intended to mean in the context of the present invention that the movement is continuous, that is to say that the moving parts have no intermediate standstill, in which case the speed of movement can be varied. The term "in one direction" means within the scope of the invention that the movement of the activation element takes place along an activation path without changing the direction of movement, wherein the activation path preferably runs linearly, particularly preferably parallel to the puncturing direction or the housing main axis (a).

In a particularly preferred embodiment of the invention, the sampling device has an operating button which projects from the distal end of the housing and is moved completely or at least partially into the housing as a result of being pressed in the proximal direction of the housing.

The actuation of the actuation part, which is preferably effected by pressing the operating button at the distal end of the housing towards the proximal end of the housing, makes it possible according to the invention for the elastic drive part of the lancet drive to initially pass from the undamped state to the clamped state and then to be triggered automatically, preferably subsequently. According to the invention, the piercing process is triggered when a predetermined point is reached, which point is reached by the activation member during the movement from the initial state to the activated state, which point is preferably predetermined by the configuration of the locking means. This makes it possible to trigger the puncturing operation independently of the force to be applied for spring clamping.

The term "automatically" is intended here to mean that the drive part, i.e. the pricking movement of the lancet or lancet holder, is triggered without further manipulation than when the trigger part is moved or pressed in the stated direction continuously.

Here, it is freely selectable which part of the movement of the actuation part along the actuation path is initially used for gripping the lancet driver, or which point on the actuation path is reached at which the lancet driver is triggered, depending on the specific design of the combined gripping and triggering mechanism. It is thus conceivable, for example, that the activation element must initially move along almost the entire activation path, the activation being effected when the maximum possible movement is completed or preferably shortly before this. Alternatively, for example, the lancet drive can already be triggered when half of the maximum activation path of the operating element is reached, but in this way the activation element is moved a short distance for the clamping of the lancet drive, which involves a large effort. It is advantageous here that it is not possible to determine when, i.e. at which moment during the movement or pressing-in of the activation member, the puncturing operation is triggered during the activation of the operating member. However, the system of the invention may also comprise suitable means for indicating that a puncturing movement is about to be triggered, if desired. These suitable means may be, for example, visible or tactile markings on the sampling system housing or on the surface of the operating element. It is particularly preferred that the means for indicating that a puncturing movement is to be triggered is part of the operating member, particularly preferably a visible or tactile marking on the surface of the operating member, for example a region which is different in color or surface condition from the rest of the operating member, preferably on the distal end of the trigger member.

According to the invention, the combined clamping and triggering device has a locking device. In principle, various technical embodiments of the locking device provided according to the invention are conceivable, in which the mechanical coupling between the actuating part and the lancet drive is designed such that the lancet drive is initially clamped and then triggered when the actuating part is moved along the actuating path. Wherein the lancet actuator is allowed to be triggered when a certain point is reached along the touch path, as previously described.

For example, a holding part which is firmly connected to the actuation part can be inserted into the lancet drive, so that the holding part at least partially engages with the drive rotor of the carousel drive when the actuation part is moved along the actuation path, thereby at least limiting, preferably preventing, the holding part from rotating.

According to a particularly preferred embodiment, the system of the invention, in particular the sampling device of the invention, comprises a locking device designed as a rail-like control, which locking device comprises as elements a control rail section and a control cam, wherein the control cam is moved relative to the control rail section during at least partial movement of the activation part along the activation path, wherein the control cam passes at least partially, preferably completely, over the control rail of the control rail section, thereby preferably controlling at least a part of the movement of the lancet driver.

In a preferred embodiment, the control cam is an integral part of the actuating element or is firmly connected to the actuating element. It is also preferred that the control rail section is an integral part of the lancet actuator or is firmly connected to an integral part of the lancet actuator. In a particularly preferred embodiment of the invention, the control rail section of the rail control is completely or at least partially but preferably completely an integral part of the drive rotor or is arranged on the drive rotor of the lancet drive as described above. It has proven advantageous here if the control rail is arranged on the outside of the drive rotor, wherein the control rail can in principle also be connected to the drive rotor in other ways, for example on an inwardly facing surface of the drive rotor, which is optionally hollow or of sleeve-like design.

According to the invention, the control cam preferably performs a relative movement with respect to the control track portion during the entire movement of the activation member from the starting position to the activation position. In this case, the control cam passes at least partially, but preferably completely, over the control rail. The control rail can be, for example, a recess in the surface of the respective component of the lancet drive. However, it is also possible to design the control rail in the form of a rail, which preferably projects beyond the surface of the respective component, preferably beyond the surface of the drive rotor, or in the form of two rails which are guided substantially parallel to one another. The control cam can then slide along one such rail or along a track formed by two rails. In a preferred embodiment, the control track comprises at least one straight section which preferably runs parallel to the rotational axis of the lancet drive or preferably parallel to the rotational axis of the drive rotor, if the control track is designed as an integral part of the drive rotor.

According to a further preferred embodiment, the control rail section comprises a preferably linear first section and a preferably linear second section, wherein the first section of the control rail section runs substantially parallel to the rotational axis of the carousel drive, preferably according to the invention, i.e. preferably parallel to the rotational axis of the drive rotor, and wherein the second section of the control rail section runs substantially perpendicular to the rotational axis of the carousel drive, preferably perpendicular to the rotational axis of the drive rotor. As used throughout this disclosure, the term "substantially parallel" or "substantially perpendicular" as used herein means that there is a small deviation from an ideal parallel or perpendicular orientation of at most about 10 °, preferably at most about 5 °, and particularly preferably at most about 2 ° (in both directions, respectively).

The first section of the control rail section preferably runs substantially parallel, preferably parallel, to the rotational axis of the carousel drive or of the drive rotor, as long as it is seated thereon, that is to say preferably parallel to the main axis (a) of the housing. The second section of the control rail section preferably extends substantially perpendicularly, preferably perpendicularly, to the axis of rotation of the carousel drive or of the drive rotor, as long as it is seated thereon. The two segments, i.e. the segments extending substantially parallel and substantially perpendicular to the rotational axis of the carousel drive or drive rotor, are preferably directly coupled to each other such that they can be successively passed by the control cam if the activation member transitions from the initial state to the activated state by a continuous movement in one direction along the activation path. In this design, the control track is formed with a substantially vertical extended trajectory. In this case, it is particularly preferred that the control track section is first passed over a section of the control track section which runs essentially parallel to the machine axis, preferably parallel to the rotational axis of the carousel drive or of the drive rotor, by the control cam. It is thereby ensured that the clamping of the drive part, which is brought about during the displacement of the activation part, is directly converted into the triggering of the lancet drive thus clamped and thus the pricking movement of the lancet holder or of the lancet held therein, which is effected only by reaching the end of the first section of the control track running substantially parallel to the axis of rotation of the drive rotor or by reaching the beginning of the second control track section running substantially perpendicular to the axis of rotation of the drive rotor, without further operating steps. In this embodiment, this is ensured in that the lancet drive, in particular the drive rotor, is first braked in rotation during the clamping as long as the control rail is seated thereon, since the control cam engages with a section of the control rail section running substantially parallel to the axis of rotation. The drive rotor is then only allowed to rotate when the end of the section running substantially parallel is reached, or when a second section running substantially perpendicular to the axis of rotation is reached. According to the invention, it is provided that the piercing movement is triggered when a predetermined point is reached along the path of movement of the activation element, in which case this trigger is determined by the end of a first section of the drive rotor running parallel to the rotational axis of the drive rotor, or by a point at which the first section of the control rail passes over into a second section of the control rail running perpendicular to the rotational axis of the drive rotor. The term "running perpendicular to the axis of rotation" or "perpendicular to the axis of rotation a" here also means, of course, a section of the control rail that runs along a circular path around the lancet drive, or a section of the control rail that runs circularly along the circumference of the drive rotor.

According to a further advantageous embodiment, the control rail may comprise, in addition to the aforementioned first and second sections, further sections which do not face substantially parallel or perpendicular to the axis of rotation of the drive rotor. It is thereby possible, for example, to advantageously provide segments which are not oriented parallel or perpendicular to the drive rotor axis of rotation, but rather form an angle with this axis of rotation of at most approximately 60 °, preferably at most approximately 40 °, particularly preferably at most approximately 20 °. Such a control rail section can be arranged, for example, between the aforementioned first section and second section of the control rail, so that when the activation element is activated, it is signaled that the drive rotor is about to be released, i.e. that penetration is about to take place.

As already mentioned, in a preferred embodiment the activation member is guided along an activation path without changing the direction of movement, wherein the activation path extends linearly, particularly preferably parallel to the puncturing direction or the housing main axis (a), particularly preferably in the direction of the housing proximal end. It is then common for the person skilled in the art that after the pricking movement of the lancet holder or the lancet releasably connected thereto, for example under the action of a suitable restoring spring, the actuating part is usually moved back into its starting position, preferably back in the direction of the distal end of the sampling device. In this case, the lancet drive, or the drive rotor, if provided, is moved back into its starting position again, so that the next pricking process can be carried out.

According to a further preferred embodiment, the system according to the invention comprises a lancet drive with a carousel drive having a transmission element with a rotatable input, by means of which a torque introduced at the input of the carousel drive is converted into a longitudinal movement in the direction of the intended puncturing path. The lancet drive is advantageously mechanically coupled to the actuation part in such a way that a movement of the actuation part along the actuation path is converted into a rotational movement of the rotatable transmission element at the input of the carousel drive in order to clamp the rotatable transmission element against the force of the elastic drive part. The rotational axis of the rotatable transmission element can be perpendicular or parallel to the puncturing direction or the housing main axis (a). The axis of rotation of the rotatable transmission element of the carousel transmission is preferably parallel to the puncturing direction or the housing main axis (a). This can be achieved, for example, by the input end of the rotary disk drive being formed by a screw element arranged on the rotatable drive element and by a clamping cam which is connected to the triggering part and can be moved along a triggering path and which can slide on a sliding surface of the screw element by means of a contact surface. Such a device is known, for example, from EP1034740a1, to which reference is made in this connection. According to a preferred embodiment, the clamping cam is firmly connected to the actuating element provided according to the invention.

As already mentioned, the system of the invention comprises a sampling device and at least one lancet matched to the sampling device. The term "at least one lancet" means here that the system comprises either one single lancet or a plurality of lancets. Within the scope of the present invention, "plurality" generally means from 2 to about 50, preferably from 3 to about 25, particularly preferably from 4 to 10, very particularly preferably from 5 to 8, further preferably 6 or 7, and most preferably 6 lancets. According to the invention, the lancets are held in a replaceable manner by the lancet holder, so that they can be removed from the lancet holder after one or, if necessary, more uses and replaced by another, preferably unused, lancet. In particular, it has proven advantageous in terms of improved operability to provide a plurality of lancets in the form of a magazine and to arrange such a magazine within the scope of the system according to the invention.

According to a preferred embodiment, the system of the invention therefore comprises a magazine with a plurality of lancets which can be coupled successively to a lancet holder. Such a magazine, often also referred to as "puncture unit", is well known to the person skilled in the art and is disclosed, for example, in WO02/36010a1, to which reference is made in particular. The magazines or pricking units preferably usable according to the invention usually comprise lancets which are often individually located in separate chambers surrounded by a magazine housing. The lancets are preferably located in the magazine housing in the rest position, i.e. before and preferably after the pricking movement. In this way, undesired injuries, in particular to used lancets, can be avoided.

The tool magazine is advantageously designed such that it can be inserted into the housing of the sampling device according to the invention. In addition, the lancet magazine is advantageously designed such that it can be mounted on the lancet drive. For this purpose, the magazine that can be used according to the invention can, for example, have the form of a cap that is fitted over the lancet drive. The magazine to be used preferably according to the invention generally has a plurality of chambers in each of which a lancet is arranged one behind the other relative to a lancet drive or lancet holder, so that the lancet can be coupled to the lancet holder designed as a plunger. For this purpose, the chambers can be arranged side by side in rows, for example. However, within the scope of the system according to the invention, it is preferred to use rotationally symmetrical tool magazines. Such a magazine, also referred to as a rotary magazine, has a chamber arranged parallel to its axis of rotation and is advantageously incorporated into the system according to the invention in such a way that its axis of rotation runs parallel to a main axis (a) of the system housing, particularly preferably coaxially. Like a turret drum, such a magazine can be repeatedly mounted on the drive unit either automatically or manually.

In a preferred embodiment of the invention, the magazine encloses at least a part of the lancet guide, particularly preferably the entire lancet guide, as disclosed in the aforementioned WO02/36010a1, see this document.

For constructional reasons, the aforementioned principle of lancet magazines often results in a considerable lengthening of the path of the lancet coupled to the lancet drive which is experienced during the pricking process compared with lancets without magazines. This also tends to make the size of such sampling systems undesirably large compared to systems without the magazine lancet.

In a further preferred embodiment, the lancets provided according to the invention or the lancets specified are each provided with a protective means which ensures that at least the respective lancet tip is sterile until a lancet which has not been used has been inserted. A suitable protector body can be pulled from the lancet, for example, prior to use. Such an antibacterially protective body is known, for example, from EP1263320, and it is particularly preferred within the scope of the present invention that it is generally made of an elastomeric material and that it is penetrated or shaved off by the lancet tip to be protected upon penetration, but preferably penetrated. A greater driving force is typically required in such systems because additional force needs to be introduced to shave off or penetrate the generally resilient guards.

The system according to the invention for removing body fluids can be constructed in a particularly compact manner, in particular with the locking device provided according to the invention, even when lancets of a magazine are used, in particular lancets additionally provided with a separate protective element.

A further advantage of the system according to the invention for removing body fluid is that, in contrast to the devices of the prior art, the lancet drive or drive part is first brought into the clamped state by clamping during use and remains in this clamped state permanently or for a freely determinable period of time until it is triggered in a separate operating step.

This latching or locking of the lancet drive in the clamped state usually entails the additional introduction of energy by the user in order to latch the lock reliably and to release the lock, i.e. in order to trigger the pricking process. In the case of a drive of preferably 360 °, this additional energy introduction is effected, for example, by an additional required angle of rotation. Since the clamping operation and the triggering operation are coupled according to the invention, an easy handling is possible, since the user does not need to exert any additional effort. Accordingly, the present invention also allows for the use of a drive component that is power-weakened in order to achieve the same drive force or speed. In particular when using a helical spring as the drive element, a helical spring with a low force constant can then be used. This brings the significant advantages of a reduction in the effort expended by the user, a reduction in the overall mechanical load of the system, and a reduction in the manufacturing costs.

It has also been shown that undesirable additional noise can be reduced, in particular when using a helical spring with a low force constant. This additional noise usually occurs when the clamped coil spring is relaxed and is generated during the relaxing movement by the spring turns striking one another, in particular on coil springs which are clamped or relaxed by axial twisting about the longitudinal axis of the coil spring.

Furthermore, the lancet drive does not latch any further in the clamped state, depending on the mechanical design chosen, which also generally leads to a considerable noise reduction during operation of the lancet system according to the invention. It has been shown that a reduction in the operating noise of the lancet system of the invention as described significantly increases the operating comfort, in particular with regard to careful use, and thus leads to significantly increased user acceptance.

Another aspect of the invention also relates to a sampling device (1) as described before, which is adapted to provide the system of the invention for taking out body fluid for diagnostic purposes. Such a sampling device preferably comprises:

-a housing (10) of a lancet that is adapted to the sampling device, the housing being provided with an extension opening for the lancet tip;

-a lancet holder (20) movable within the housing (10) along a predetermined pricking path for replaceably holding a lancet (91);

-a lancet guide (92) for guiding the lancet holder (20) over a predetermined pricking path after triggering the pricking movement;

-a lancet driver (30) with an elastic drive part (31), which can be transferred by clamping from an undamped state to a clamped state, with which the relaxing movement of the clamped elastic drive part (31) is converted into a pricking movement after triggering, wherein a lancet (91) held by a lancet holder (20) is moved along a predetermined pricking path in the pricking direction until the lancet tip at least partially protrudes from the protrusion opening, whereby the lancet holder (20) returns to the position of the lancet tip of the lancet (91) in the housing (10); and

-a combined grip and trigger mechanism with an activation part (40) accessible from outside the housing (10), the activation part having an initial state and an activated state, wherein the combined grip and trigger mechanism has a locking device (70) mechanically coupled with the activation part (40) and the lancet driver (30) such that the lancet driver (30) is initially gripped and then activated when the activation part (40) moves along an activation path, wherein the activation of the lancet driver (30) is allowed when a certain point along the activation path is reached.

The invention will be described in detail below with the aid of an embodiment shown in the drawing. The figures herein provide preferred embodiments of the invention, in which the features shown can be combined with each other at will.

FIG. 1a is a cross-sectional view of the system of the present invention with a lancet magazine inserted;

FIG. 1b is an enlarged partial view of the cross-sectional lancet magazine of FIG. 1 a;

FIG. 2 is a perspective cross-sectional view of the system of FIG. 1 a;

FIG. 3 is a perspective view of a sampling device of the system of the present invention without the housing;

FIG. 3a is an isolated view of the locking device;

FIG. 4 is a side view of the extraction system of FIG. 3 prior to movement of the actuation member, i.e., in an initial state;

FIG. 5 is a side view of the sampling device of FIG. 3 with the actuation member in an actuated state;

FIG. 6 is a side view of the sampling device of FIG. 3 with the drive rotor having been rotated and the lancet holder moved in the lancing direction;

FIG. 7 is a side view of the rear side of the sampling device shown in FIG. 6;

FIG. 8 is a detail of the drive of the output with the lancet holder of the sampling device shown in FIGS. 3 to 7;

FIG. 9 is a simplified detail of the drive of the output with the lancet holder of the sampling device shown in FIGS. 3 to 7 without the drive rotor;

FIG. 10 is a perspective view of the lancet holder shown in FIGS. 8 and 9;

FIG. 11 is a perspective view of the sampling device shown in FIG. 1a with the lancet magazine inserted, without the housing.

List of reference numerals:

1 sampling device

2 proximal end of extraction System

3 distal end of extraction System

10 casing

11 proximal end of the housing

12 distal end of the housing

20 lancet holder/pusher

Coupling body of lancet holder 21 (holding device)

30 lancet actuator

31 elastic drive part

40 touch part

50 driving rotor

60 curve type control part

61 puncture curve part/puncture trace part

62 control latch

63 locking sleeve

70 locking device

71 control cam

72 first section of control rail portion

73 second section of the control rail part

80 helical clamping pin

81 clamping cam

82 clamping sleeve

90 lancet magazine

91 lancet

92 lancet guide

93 lancet holding area

94 antibacterial protection.

Fig. 1 and 2 show cross-sectional views taken along the main axis of rotation or main device axis (a) of the system of the invention, which according to the form shown comprises a sampling device (1) and a lancet magazine (90). Fig. 3 to 11 show details of the sampling device in a partial side view, in a partial perspective view. The lancet magazine (90) forms the proximal end (2) of the system and is inserted into the proximal end (11) of the housing (10). An actuation member (40) forms the distal end (3) of the system and extends from the distal end (12) of the housing (10). The system has a lancet drive (30) in the form of a rotary disk drive, which is connected via a drive rotor (50) to a clamping spring designed as a torsion spring, which acts as an elastic drive part (31). The lancet drive is connected at the output to a lancet holder (20) which is designed as a plunger and which has a holding device (21) at its proximal end for releasably holding a lancet (91) by means of a positive-locking coupling to its holding region (93) and which is connected to the drive (50) of the input via a feed sleeve (63), see fig. 4 to 10). The lancet magazine (90) provided in this embodiment comprises a lancet guide (92) with which the lancet holder or a lancet (91) releasably connected thereto is guided over a predetermined pricking path parallel to the rotational axis (A) of the system. The lancets stored in the magazine each have a protective seal (94) which sealingly encloses at least the respective lancet tip. This detail is shown in the enlarged partial view of fig. 1 b. According to this embodiment, the lancet guide (92) is designed as an integral part of the lancet magazine (90). If no such magazine is provided, i.e. the system according to the invention has a plurality of individual lancets, the lancet guide can of course also be designed in other ways in this case, for example as a component of the housing, i.e. for example arranged on the inside of the housing.

The drive rotor (50) of the carousel drive is supported (at the output) in an axial position fixed with reference to the machine axis (a) and is coupled, by means of a drive spring (31), to the drive designed as the input of a helical clamping pin (80). The clamping pin (80) has a screw with a contact surface on which a clamping cam (81) connected to the trigger part is slidingly supported. The clamping cam (81) can also be coupled with the triggering part (40) by means of a clamping sleeve (82) as shown in fig. 2.

Before the pricking movement is carried out, the lancet (91) is coupled to the lancet drive (30) each time. According to the embodiment shown, this is achieved by means of a lancet holder (20) which is designed as a plunger. A thickened holding device (coupling body) (21) is provided at the end of the plunger (20) facing the lancet (91), and for coupling the lancet (91), the holding device is inserted into the corresponding holding device in a holding section (93) of the lancet body (91). The holding device of the lancet body (91) is designed such that it geometrically couples with the holding part (21) of the plunger (20) when the plunger (20) is moved a certain distance in the pricking direction such that its front end contacts the lancet body and the lancet (91) is moved in the pricking direction. Thereby the lancet (91) is positively coupled with the lancet drive (30). Specific details and alternative embodiments of suitable coupling mechanisms are described in international patent application WO02/36010a1, the contents of which are incorporated herein by reference.

According to the preferred embodiment shown, the lancet (91) is "guided directly", that is to say it is located immediately in the part of the housing (10) which forms the required guide (92) during the pricking movement, in the present case a magazine (90) containing a plurality of lancets. The following embodiments of the lancet driver (30) of the invention are particularly suitable for such directly guided lancets (91) of a magazine. It is also possible to use indirect lancet guides, which were used in the past, in which the lancet drive is permanently coupled to the lancet holder, into which a new lancet is manually inserted each time blood is removed. During the pricking process, the lancet holder (20) is guided by means of a housing or magazine part (92) which serves as a guide and is thus indirectly responsible for guiding the lancet (91) as required in the pricking path.

Fig. 3 shows a perspective view of the inventive sampling device (1) from fig. 1 and 2, wherein the housing (10) and the lancet magazine (90) are omitted for the sake of illustration of the operating mode. The sampling device (1) shown has a locking device (70) designed as a rail-like control (72, 73) connected to the triggering part (40). The locking device has, on its side facing the interior of the apparatus (not visible in fig. 3), a control cam (71) which is mounted so as to be movable along a control rail (72, 73), wherein the control rail or a control rail section (72, 73) is mounted on a rotatable drive rotor (50) of the carousel drive. The control cam (71) can thereby be moved relative to the control rails (72, 73) when the triggering part (40) is moved parallel to the main axis (A) of the device, wherein the control cam slides over or along the respective section of the control rails. According to this embodiment, the control rail of the control rail section has two sections (72, 73), wherein a first section (72) extends substantially parallel to the main machine axis (a), i.e. parallel to the rotational axis of the drive rotor (50) of the carousel drive. The first section (72) of the control rail directly merges into a second section (73), wherein the second section (73) extends substantially perpendicularly to the main device axis (A), i.e. perpendicularly to the rotational axis of the drive rotor (50) of the carousel drive. The locking device (70) is shown in isolation again in fig. 3 a. Here, the activating member (40) is shown transparent so that the control cam (71) facing the drive rotor (50) can be seen.

As can be seen in particular from fig. 4 to 7, the drive rotor (50) which is rotatable about the main unit axis (a) is under the influence of a resilient drive element (31) which is designed as a torsion spring (referred to below as drive spring). One end of the drive spring (31) is connected to the drive rotor (50) and the other end is connected to a transmission element designed as the input end of a helical clamping pin (80). In this embodiment, the drive spring (31) is clamped by rotation of a helical clamping pin (80) against the action of its spring force, wherein the actuation part (40) is moved towards the proximal end (2) of the extraction system, causing rotation of the helical clamping pin (80). A clamping cam (81) is slidably supported on the screw of a helical clamping pin (80), which is supported in a rotationally fixed manner and is firmly connected to the trigger part (40), and is axially displaced, i.e. parallel to the main device axis (A) towards the housing proximal end, thereby causing the transmission member, which is designed as the input end of the helical clamping pin (80), to rotate and thus the drive spring (31) to clamp.

Fig. 4 to 6 show the operation of the sampling device shown in fig. 1 to 3 over time. The components shown in connection with the above figures are labeled with the same reference numerals throughout the disclosure, and thus are not described again. In fig. 4, the sampling device of the present invention is shown in an initial state, i.e. prior to movement of the trigger member (40). The clamping cam is located inside (not visible) the clamping sleeve (82). The control cam (71) is located at the start of a first section (72) of the control rail portion of the rail-type control member extending parallel to the axis of rotation of the drive rotor. The activating member (40) is shown transparent. The drive rotor (50) of the carousel and the lancet holder (20) are in their initial positions. The actuation member (40) is then moved towards the proximal end (2) of the extraction system, thereby transitioning from the initial state shown in fig. 4 to the actuated state. In this case, a clamping cam (81), which is not visible in fig. 4, which is arranged in the clamping sleeve (82), slides along the spiral of the helical clamping pin (80), which rotates as a result, so that the drive spring (31) is clamped against the stationary drive rotor (50) held by the control cam (71) of the rail-type control element. At the same time, a control cam (71) firmly connected to the activation member (40) by means of a locking device (70) passes, towards the proximal end of the extraction system, through a first section (72) of the control rail extending parallel to the axis of rotation of the drive rotor, until the control cam (71) reaches the beginning of a second section (73) extending perpendicular to the axis of rotation of the carousel drive or of the drive rotor. The trigger member (40) is maximally moved towards the proximal end (2) of the sampling device, which state is shown in fig. 5. In this state, the drive rotor (50) starts to rotate about its rotational axis (A) by the elastic force of the clamped drive spring (31). At this time, the feed sleeve (63) and the lancet holder (20) firmly connected thereto are still at the initial position at which the pricking movement is started.

Fig. 6 shows a temporally subsequent state of the sampling device according to the invention, in which the drive rotor (50) has been rotated approximately 90 ° about its axis of rotation and the lancet holder (20) guided by the curve is already in a position deflected into the pricking direction. Fig. 7 shows the same state of the sampling device, however, viewed from the opposite side. Here too, the coupling mechanism on the output side, which is designed as a curved control element (60), can be seen.

With the coupling mechanism on the output side shown in fig. 8 to 10, the rotary movement of the drive rotor (50) is converted into a pricking movement, which is transmitted via the lancet holder (20) to the lancet (91) coupled thereto. In the illustrated case, the coupling means on the output side are formed by a curved control element (60) having a control curve or control path (61) and a control bolt (62) which passes through the control curve or control path (61) during the puncturing movement. According to the embodiment shown, the control cam (61) is formed by a recess running around the circumference of the feed sleeve (63). The control bolt (62) is formed on a drive rotor (50) which is surrounded by the section of the feed sleeve (63) provided with the piercing curve/piercing path (61).

The feed sleeve (63) is guided in a rotationally fixed manner by means of longitudinal grooves, not shown, so that it can only move in a translatory manner. The front end of the lancet holder (20) is rigidly fixed.

The operation of the curved control member (60) is substantially the same as that described in US5,318,584 and EP1034740a 1. The main difference, however, is that the drive rotor (50) does not have to be rotated back during the clamping of the drive spring (31). On the one hand, this ensures a very simple design of the lancet curve/lancet track (61) and, on the other hand, a full rotation angle of 360 ° can be used for converting the rotational movement of the drive rotor (50) into a translational movement of the lancet holder (20) and of the lancet (91) connected thereto.

This can be achieved in that the clamping mechanism is preferably designed according to the invention according to the OWADAC principle (onewayalternative driving and clamping), as disclosed in EP1384438a1, see this document for the sake of clarity. The end of the drive spring (31) facing away from the drive rotor (50) bears against a transmission element, which is designed as the input end of a helical clamping pin (80) and which can be rotated in the same rotational direction in which the drive rotor (50) is rotated during the puncturing movement, in order to clamp the drive spring (31) when the drive rotor (50) is prevented from rotating. During the pricking movement, the helical clamping pin (80) is locked against rotation back, so that the drive rotor (50) performs a rotational movement after the locking means preventing its rotation has been released, which rotational movement is converted into a pricking movement of the lancet (91).

Finally, fig. 11 shows a perspective view of the sampling device (1) shown in fig. 1a with the lancet magazine (90) inserted, but without the housing (10).

Claims (13)

1. A system for removing body fluid for diagnostic purposes, comprising:

-a sampling device (1) and at least one lancet (91) matched to the sampling device (1), with a lancet body and a lancet tip;

-a housing (10) with an extension opening for the lancet tip;

-a lancet holder (20) movable within the housing (10) along a predetermined pricking path for replaceably holding a lancet (91);

-a magazine (90) with a plurality of lancets (91) which can be coupled one after the other to the lancet holder (20) and which is adapted to the sampling device (1) and which has a lancet body and a lancet tip, wherein the lancets provided are each provided with a protective shield (94) which ensures the sterility of the lancet which has not been used until the insertion, is composed of an elastomer material and is penetrated or chipped off by the lancet tip to be protected during the insertion;

-a lancet guide (92) for guiding the lancet holder (20) over a predetermined pricking path after triggering the pricking movement;

-a lancet driver (30) with an elastic drive part (31), which can be transferred by clamping from an undamped state to a clamped state, with which the relaxing movement of the clamped elastic drive part (31) is converted into a pricking movement after triggering, wherein a lancet (91) held by a lancet holder (20) is moved along a predetermined pricking path in the pricking direction until the lancet tip at least partially protrudes from the protrusion opening, whereby the lancet holder (20) returns to the position of the lancet tip of the lancet (91) in the housing (10); and

-a combined grip and trigger mechanism with an activation part (40) accessible from outside the housing (10), the activation part having an initial state and an activated state, wherein the combined grip and trigger mechanism has a locking device (70) mechanically coupled with the activation part (40) and the lancet driver (30) such that the lancet driver (30) is initially gripped and then activated when the activation part (40) moves along an activation path, wherein the activation of the lancet driver (30) is allowed when a certain point along the activation path is reached.

2. A system according to claim 1, wherein the locking device (70) is designed as a rail-like control, which locking device comprises as elements a control rail portion and a control cam (71), wherein the control cam (71) is relatively movable with respect to the control rail portion during at least partial movement of the activation member (40) along the activation path, wherein the control cam at least partially passes the control rail of the control rail portion.

3. A system as claimed in claim 1, characterized in that the lancet drive (30) has a carousel drive with a rotatable drive rotor (50) with which a torque introduced at the input of the carousel drive is converted into a longitudinal movement in the direction of the predetermined pricking path, wherein the drive rotor (50) is coupled to an elastic drive part (31) and the longitudinal movement of the output of the carousel drive is transmitted to the lancet holder (20).

4. A system as claimed in claim 2, characterized in that the lancet drive (30) has a carousel drive with a rotatable drive rotor (50) with which a torque introduced at the input of the carousel drive is converted into a longitudinal movement in the direction of the predetermined pricking path, wherein the drive rotor (50) is coupled to an elastic drive part (31) and the longitudinal movement of the output of the carousel drive is transmitted to the lancet holder (20).

5. System according to claim 4, characterized in that the control rail part of the rail-like control is at least partly arranged on the drive rotor (50).

6. System according to claim 4, wherein the control rail part comprises a first section (72) and a second section (73), wherein the first section (72) of the control rail part extends substantially parallel to the rotational axis of the carousel drive, wherein the second section (73) of the control rail part extends substantially perpendicular to the rotational axis of the carousel drive.

7. A system according to any of the preceding claims 1-2, characterized in that the resilient drive member of the lancet drive is initially transferred from the undamped to the clamped state by a continued movement of the actuation member in one direction, followed by triggering.

8. A system according to any of the preceding claims 1-2, characterized in that the activating member (40) is an operating button protruding from the end of the housing (10) facing away from the rear of the protrusion opening of the lancet tip.

9. System according to claim 3 or 4, characterized in that the rotary disk drive has a curved control element (60) with a recess which forms a control curve (61) and is rotatable together with the drive rotor (50), in which recess a matching control bolt (62) is inserted, wherein at least a part of the penetration and return movement is determined by the relative movement between the control bolt (62) and the recess, wherein the control bolt (62) passes through the control curve formed by the recess.

10. System according to claim 3 or 4, characterized in that the input of the carousel drive is constituted by a screw element arranged on the carousel drive and by a clamping cam (81) connected to the actuation member (40) and movable along an actuation path on a sliding surface of the screw element by means of a contact surface.

11. The system of any of the preceding claims 1-2, wherein the magazine (90) encloses at least a portion of the lancet guide (92).

12. A system according to any of the preceding claims 1-2, characterized in that the lancet (91) is mechanically coupled to the lancet driver (30) during the entire pricking process.

13. A system according to any of the preceding claims 1-2, characterized in that the system comprises means for indicating that a puncturing movement is about to be triggered.