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Application filed by The Regents Of The University Of CaliforniafiledCriticalThe Regents Of The University Of California
Publication of HK1176965ApublicationCriticalpatent/HK1176965A/en
Publication of HK1176965BpublicationCriticalpatent/HK1176965B/en
The present disclosure provides variant Csy4 endoribonucleases, nucleic acids encoding the variant Csy4 endoribonucleases, and host cells genetically modified with the nucleic acids. The variant Csy4 endoribonucleases find use in a variety of applications, which are also provided. The present disclosure also provides methods of detecting a specific sequence in a target polyribonucleotide and methods of regulating production of a target RNA in a eukaryotic cell.
HK13103830.3A2010-05-102011-05-09Endoribonuclease compositions and methods of use thereof
HK1176965B
(en)
Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof
Pharmaceutical compositions with resistance to soluble cea, bispecific antibodies binding cea, nucleic acid sequences encoding the antibodies and vectors and host cells comprising the nucleic acids as well as processes for the production thereof, uses thereof and corresponding kits
Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same